Chloride Channel

  • 抑制剂选择性比较
  • 溶解性比较
目录号 产品目录 溶解度(25°C)
DMSO 酒精
S8279 Shikonin <1 mg/mL 57 mg/mL 23 mg/mL
S3807 Dehydroandrographolide -1 mg/mL 66 mg/mL -1 mg/mL
S1675 Lubiprostone <1 mg/mL 78 mg/mL 78 mg/mL
S1351 Ivermectin <1 mg/mL 100 mg/mL 28 mg/mL
产品目录 产品描述 文献引用 实验数据
S8279

Shikonin

Shikonin,是一种Pyruvate kinase M2 (PKM2)有效的、特异的抑制剂。它是紫草的主要成分,紫草是一种中草药,具有多种生物活性。在细胞荧光淬灭试验中,Shikonin也是TMEM16A氯离子通道的抑制剂。

S3807New

Dehydroandrographolide

Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.

S1675

Lubiprostone

Lubiprostone是ClC-2氯离子通道的激活剂。一种胃肠药,用于治疗突发性慢性便秘。

S1351

Ivermectin

Ivermectin是一种chloride channel激活剂,用作广谱抗寄生虫药。

Tags: Chloride Channel inhibitor | Chloride Channel activator | Chloride Channel blocker