Recombinant Human Kallikrein 5/KLK5 Protein, CF (HEK293) is expressed from HEK293 cells with an His tag at the C-terminus.
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Recombinant Human Kallikrein 5/KLK5 Protein , C-His, CF (HEK293) on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
使用信息
物种
Human
标签
His tag at the C-terminus.
来源
HEK293-drived Human Kallikrein 5/KLK5 Protein AA Ile67-Ser293.
预测分子量
26.5 kDa
实际分子量
35-50 kDa, reducing conditions
纯度
>95% as determined by Bis-Tris PAGE.
内毒素
< 0.1 EU/ug by the LAL method
制剂
Lyophilized from 0.22 μm filtered solution in 50mM MES, 150mM NaCl (pH 5.5). Normally 8% trehalose is added as protectant before lyophilization.
储存条件 (自收到货起)
For long-term storage, keep the product lyophilized at -20°C or below. Please avoid repeated freeze-thaw cycles.
Stability:
Lyophilized: 12 months (-20°C to -80°C)
Reconstituted: 3 months at -80°C under sterile conditions.
生物描述
产品信息
Recombinant Human Kallikrein 5/KLK5 Protein, CF (HEK293)：由 HEK293 细胞表达，C 端带有 His 标签。
Accession
Q9Y337
别名
KLK-L2, KLK5, SCTE
背景
人组织激肽释放酶 5（hK5，又称角质层胰蛋白酶）是人组织激肽释放酶基因家族的丝氨酸蛋白酶。人 KLK5 推导氨基酸序列包含信号肽（Met1～Gly22）、前肽区（Val23～Arg66）以及成熟活性酶区（Ile67～Ser293）。KLK5 主要在皮肤、乳腺、脑和睾丸中表达，在其他多种组织中低水平表达。KLK5 过表达是卵巢癌预后不良的标志物。
参考文献
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