MALT
抑制剂选择性比较
特异性亚型抑制剂
MALT产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
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S8898 |
MLT-748MLT-748 是一种有效的、选择性的 MALT1 的变构抑制剂,IC50值为5 nM。MLT-748 通过置换 Trp580 而结合在半胱天冬酶和免疫球蛋白 (Ig3) 域之间的交界面上并将催化位点锁定在非活性的状态。 |
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S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) 是不可逆的MALT1抑制剂,其IC50为 5.84 μM。 |
![]() ![]() (a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
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S9896New |
JNJ-67856633JNJ-67856633 (JNJ-6633) 是一种有效的、选择性的 MALT1 protease 变构抑制剂。 |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S8898 |
MLT-748MLT-748 是一种有效的、选择性的 MALT1 的变构抑制剂,IC50值为5 nM。MLT-748 通过置换 Trp580 而结合在半胱天冬酶和免疫球蛋白 (Ig3) 域之间的交界面上并将催化位点锁定在非活性的状态。 |
||
S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) 是不可逆的MALT1抑制剂,其IC50为 5.84 μM。 |
![]() ![]() (a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
|
|
S9896New |
JNJ-67856633JNJ-67856633 (JNJ-6633) 是一种有效的、选择性的 MALT1 protease 变构抑制剂。 |