MALT
抑制剂选择性比较
MALT产品
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S8898New |
MLT-748MLT-748 是一种有效的、选择性的 MALT1 的变构抑制剂，IC50值为5 nM。MLT-748 通过置换 Trp580 而结合在半胱天冬酶和免疫球蛋白 (Ig3) 域之间的交界面上并将催化位点锁定在非活性的状态。 |
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| S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) 是不可逆的MALT1抑制剂，其IC50为 5.84 μM。 |
(a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
|
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S8898New |
MLT-748MLT-748 是一种有效的、选择性的 MALT1 的变构抑制剂，IC50值为5 nM。MLT-748 通过置换 Trp580 而结合在半胱天冬酶和免疫球蛋白 (Ig3) 域之间的交界面上并将催化位点锁定在非活性的状态。 |
||
| S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) 是不可逆的MALT1抑制剂，其IC50为 5.84 μM。 |
(a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
|
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