AdipoR
- 抑制剂选择性比较
- 溶解性比较
| 目录号 | 产品目录 | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | 酒精 | ||
| S7365 | AdipoRon | <1 mg/mL | 86 mg/mL | 50 mg/mL |
| S3822 | Schisandrin A | -1 mg/mL | 83 mg/mL | -1 mg/mL |
| S4738 | Arctiin | 40 mg/mL | 100 mg/mL | 100 mg/mL |
- AdipoR抑制剂（3）
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S7365 |
AdipoRonAdiporon 是一种新型的口服作用于脂联素受体的激动剂，针对脂联素受体1和脂联素受体2的KD分别为1.8 和 3.1 μM。 |
AdipoRon attenuates Ang II-induced vascular injury. (A) Immunofluorescence analysis of p-p38 and quantification of its protein expression levels, in Sham, Ang II and Ang II+ AdipoRon-treated mice (scale bar, 100 µm). Representative images of (B) Sirius Red (scale bar, 200 µm) and (C) hematoxylin and eosin staining (scale bar, 50 µM) of aorta cross sections from sham, Ang II and Ang II+ AdipoRon-treated mice. Data are expressed as the mean ± standard deviation (n=5). *P<0.05 vs. sham, #P<0.05 vs. Ang II. Ang II, angiotensin; p-p38, phosphorylated-p38
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| S3822 |
Schisandrin ASchisandrin A (Sch A) is an active component of Schisandrae Fructus with liver-protective, antitumor, and antioxidant activities. It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM. |
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| S4738 |
ArctiinArctiin是脂联素受体1的激动剂，具有抗肿瘤活性。 |
