| S5771 |
Sulforaphane
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Sulforaphane 是一种天然存在的异硫氰酸盐，存在于十字花科蔬菜如西兰花、卷心菜、羽衣甘蓝。它是 Nrf2 的诱导物。Sulforaphane 也是 histone deacetylase (HDAC) 和 NF-κB 的抑制剂。Sulforaphane 可增加 heme oxygenase-1 (HO-1)，并降低 reactive oxygen species (ROS) 的水平。Sulforaphane 诱导细胞周期停滞和凋亡。 |
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J Clin Invest, 2025, 135(14)e176655
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Sci Rep, 2025, 15(1):21271
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BMC Cancer, 2025, 25(1):1050
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| S5645 |
Hemin
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Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.This product has poor solubility, animal experiments are available, cell experiments please choose carefully! |
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Sci Rep, 2025, 15(1):13159
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Biochem J, 2025, 482(12):859-75
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Hum Cell, 2024, 10.1007/s13577-024-01034-5
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| S7880 |
Protoporphyrin IX Zinc
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Zinc Protoporphyrin (Zn(II)-protoporphyrin IX)是一种有效的、具有口服活性和竞争性的 血红素加氧酶-1(heme oxygenase-1, HO-1)抑制剂，可显着降低间苯三酚(Phloroglucinol, PG)对过氧化氢的保护作用。此产品溶解度不佳，动物实验可用，细胞实验请谨慎选择！ |
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Sci Rep, 2025, 15(1):18949
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Nat Commun, 2024, 15(1):9050
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| S9503 |
Fraxetin
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Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity. |
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Life (Basel), 2023, 13(5)1112
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Life (Basel), 2023, 1112
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| S9221 |
Ferulaldehyde
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Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora. |
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| S7879 |
Tin protoporphyrin IX dichloride
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Tin Protoporphyrin IX (NSC 267099, SnPPIX, Sn-Protoporphyrin) 是 血红素加氧酶-1 (HO-1) 的强效抑制剂，可减轻臭氧引起的肺部炎症和 BAL 细胞坏死，从而突出其保护作用。它还能在小鼠模型中增强胰腺导管腺癌 (PDAC) 肿瘤对化疗的敏感性，表明其具有治疗 PDAC 的潜力。 |
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| E3438 |
Momordica grosvenori Extract
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Momordica Grosvenori Extract从罗汉果Siraitia grosvenorii中提取，通过上调HO-1而具有抗糖尿病作用，可用于治疗糖尿病。 |
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| E0526 |
sappanone A
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Sappanone A是从豆科苏木心材中分离得到的一种异黄酮类化合物，通过p38 MAPK通路激活Nrf2，诱导HO-1表达，并通过抑制RelA/p65在Ser536位点的磷酸化来抑制脂多糖诱导的NF-κB的激活，发挥其抗炎作用。 |
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| S7880 |
Protoporphyrin IX Zinc
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Zinc Protoporphyrin (Zn(II)-protoporphyrin IX)是一种有效的、具有口服活性和竞争性的 血红素加氧酶-1(heme oxygenase-1, HO-1)抑制剂，可显着降低间苯三酚(Phloroglucinol, PG)对过氧化氢的保护作用。此产品溶解度不佳，动物实验可用，细胞实验请谨慎选择！ |
- Sci Rep, 2025, 15(1):18949
- Nat Commun, 2024, 15(1):9050
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| S9503 |
Fraxetin
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Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity. |
- Life (Basel), 2023, 13(5)1112
- Life (Basel), 2023, 1112
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| S7879 |
Tin protoporphyrin IX dichloride
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Tin Protoporphyrin IX (NSC 267099, SnPPIX, Sn-Protoporphyrin) 是 血红素加氧酶-1 (HO-1) 的强效抑制剂，可减轻臭氧引起的肺部炎症和 BAL 细胞坏死，从而突出其保护作用。它还能在小鼠模型中增强胰腺导管腺癌 (PDAC) 肿瘤对化疗的敏感性，表明其具有治疗 PDAC 的潜力。 |
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