PDHK

AZD7545 mediated growth suppression of BRAFV600E mutant and NRASmut melanoma cells. Twenty-four hours after plating, both A375 and IGR37 cell lines (BRAFV600E) (a) and SKMel30, IPC298 and MelJuso cell lines (NRASmut) (b) were treated with 10 μM of AZD7545. The plates were imaged using an IncuCyte ZOOM live cell microscope (Essen BioScience) and images were taken every 3 h for a total of 90 h (BRAFV600E) and 120 h (NRASmut). Results are shown for one representative of three biological replicates

AZD7545 mediated growth suppression of BRAFV600E mutant and NRASmut melanoma cells. Twenty-four hours after plating, both A375 and IGR37 cell lines (BRAFV600E) (a) and SKMel30, IPC298 and MelJuso cell lines (NRASmut) (b) were treated with 10 μM of AZD7545. The plates were imaged using an IncuCyte ZOOM live cell microscope (Essen BioScience) and images were taken every 3 h for a total of 90 h (BRAFV600E) and 120 h (NRASmut). Results are shown for one representative of three biological replicates