PTEN

PTEN产品

  • 所有产品(7)
  • PTEN抑制剂 (3)
  • PTEN抗体 (2)
  • PTEN激活剂 (2)
目录号 产品名 产品描述 文献引用 实验数据
S7310 SF1670 SF1670是一种高度有效且专一的PTEN的抑制剂,其IC50 为 2 μM。
Fish Shellfish Immunol, 2024, 146:109384
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂,IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。
Protein Cell, 2023, 14(5):350-368
Adv Sci (Weinh), 2023, 10(13):e2205436
Cell Death Discov, 2023, 9(1):82
S8174 VO-Ohpic trihydrate VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂,IC50为35 nM。
Aging (Albany NY), 2023, 15(6):2275-2292
Stem Cell Res Ther, 2020, 11(1):140
Life Sci, 2020, 25;253:117718
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。
A5040 PTEN Rabbit Recombinant mAb
A5085 PTEN Rabbit Recombinant mAb
S7310 SF1670 SF1670是一种高度有效且专一的PTEN的抑制剂,其IC50 为 2 μM。
Fish Shellfish Immunol, 2024, 146:109384
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂,IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。
Protein Cell, 2023, 14(5):350-368
Adv Sci (Weinh), 2023, 10(13):e2205436
Cell Death Discov, 2023, 9(1):82
S8174 VO-Ohpic trihydrate VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂,IC50为35 nM。
Aging (Albany NY), 2023, 15(6):2275-2292
Stem Cell Res Ther, 2020, 11(1):140
Life Sci, 2020, 25;253:117718
A5040 PTEN Rabbit Recombinant mAb
A5085 PTEN Rabbit Recombinant mAb
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。

PTEN抑制剂选择性比较

Tags: PTEN inhibitor|PTEN agonist|PTEN activator|PTEN inducer|PTEN antagonist|PTEN signaling pathway|PTEN assay kit
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