PTEN
- 抑制剂选择性比较
- 溶解性比较
| 目录号 | 产品目录 | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | 酒精 | ||
| S7310 | SF1670 | <1 mg/mL | 29 mg/mL | 1 mg/mL |
| S8651 | bpV (HOpic) | 69 mg/mL | <1 mg/mL | <1 mg/mL |
| S8174 | VO-Ohpic trihydrate | <1 mg/mL | 72 mg/mL | <1 mg/mL |
- PTEN抑制剂（3）
- 新PTEN产品
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S7310 |
SF1670SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。 |
Adiponectin (APN) combined with SF1670 promotes osteogenesis of human bone marrow stromal cells (hBMSCs). Cells were cultured in proliferation medium (PM) and osteoinduction conditioned medium (OM). The expression of osteogenic differentiation-related genes in hBMSCs cultured in OM with 1.0 μg/mL APN combined with 5 μM SF1670 at day 7 (a, b) and day 14 (c, d).
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| S8651New |
bpV (HOpic)bpV (HOpic)是一种有效的PTEN抑制剂，IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。 |
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| S8174 |
VO-Ohpic trihydrateVO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。 |
