PTEN

PTEN产品

目录号	产品描述	文献引用	实验数据
S7310	SF1670 SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。	Cell Mol Immunol, 2020, 10.1038/s41423-020-0363-5 Aging (Albany NY), 2020, 13;12(7):6352-6369 Biochem Pharmacol, 2020, 171:113674	A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
S8651	bpV (HOpic) bpV (HOpic)是一种有效的PTEN抑制剂，IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。	J Cell Mol Med, 2020, 24(1):61-78 J Diabetes Res, 2020, 31;2020:9481720 J Cell Mol Med, 2020, 10.1111/jcmm.15648
S8174	VO-Ohpic trihydrate VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。	Aging (Albany NY), 2020, 24;12(2):1213-1236 Life Sci, 2020, 25;253:117718 Eur Rev Med Pharmacol Sci, 2020, 24(6):2811-2819
S9190	Oroxin B Oroxin B, one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.

目录号	产品描述	文献引用	实验数据
S7310	SF1670 SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。	Cell Mol Immunol,2020, 10.1038/s41423-020-0363-5 Aging (Albany NY),2020, 13;12(7):6352-6369 Biochem Pharmacol,2020, 171:113674	A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
S8651	bpV (HOpic) bpV (HOpic)是一种有效的PTEN抑制剂，IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。	J Cell Mol Med,2020, 24(1):61-78 J Diabetes Res,2020, 31;2020:9481720 J Cell Mol Med,2020, 10.1111/jcmm.15648
S8174	VO-Ohpic trihydrate VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。	Aging (Albany NY),2020, 24;12(2):1213-1236 Life Sci,2020, 25;253:117718 Eur Rev Med Pharmacol Sci,2020, 24(6):2811-2819

目录号	产品描述	文献引用	实验数据
S9190	Oroxin B Oroxin B, one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.