PTEN
抑制剂选择性比较
PTEN产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
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S7310 |
SF1670SF1670是一种高度有效且专一的PTEN的抑制剂,其IC50 为 2 μM。 |
![]() ![]() A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
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S8651 |
bpV (HOpic)bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂,IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。 |
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S8174 |
VO-Ohpic trihydrateVO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂,IC50为35 nM。 |
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S9190 |
Oroxin BOroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment. |
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S0918 |
Ginkgolic acid C17:1Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2 和 Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。 |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S7310 |
SF1670SF1670是一种高度有效且专一的PTEN的抑制剂,其IC50 为 2 μM。 |
![]() ![]() A、total of 1.5 μM PTEN inhibitor SF1670 inhibited the expression of PTEN and decreased the level of CD11b
|
|
S8651 |
bpV (HOpic)bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂,IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。 |
||
S8174 |
VO-Ohpic trihydrateVO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂,IC50为35 nM。 |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S9190 |
Oroxin BOroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment. |
||
S0918 |
Ginkgolic acid C17:1Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2 和 Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。 |