PTEN
- 抑制剂选择性比较
- 溶解性比较
| 目录号 | 产品目录 | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | 酒精 | ||
| S7310 | SF1670 | <1 mg/mL | 29 mg/mL | 1 mg/mL |
| S8651 | bpV (HOpic) | 69 mg/mL | <1 mg/mL | <1 mg/mL |
| S8174 | VO-Ohpic trihydrate | <1 mg/mL | 72 mg/mL | <1 mg/mL |
- PTEN抑制剂（3）
- 新PTEN产品
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S7310 |
SF1670SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。 |
Adiponectin (APN) combined with SF1670 promotes osteogenesis of human bone marrow stromal cells (hBMSCs). Cells were cultured in proliferation medium (PM) and osteoinduction conditioned medium (OM). The expression of osteogenic differentiation-related genes in hBMSCs cultured in OM with 1.0 μg/mL APN combined with 5 μM SF1670 at day 7 (a, b) and day 14 (c, d).
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| S8651New |
bpV (HOpic)bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively. |
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| S8174 |
VO-Ohpic trihydrateVO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。 |
