免费电话：400-668-6834 | 技术支持：400-168-6834 | 邮箱：info@selleck.cn

PD-1/PD-L1治疗性抗体（Pembrolizumab，Atezolizumab，Nivolumab）重磅上市！

首页
抑制剂
- 研究领域
- PI3K/Akt/mTOR
  - PI3K
  - mTOR
  - Akt
  - GSK-3
  - ATM/ATR
  - PDK
  - S6 Kinase
  - AMPK
  - DNA-PK
  - MELK
  - PIKfyve
  - PI4K
- Epigenetics
- Methylation
  - DNA Methyltransferase
  - LSD1
  - DOT1
  - COMT
  - EZH1/2
  - PPMTase
  - MLL
  - SAM MTase
  - SETD
  - WDR5
  - PRMT
  - G9a/GLP
  - SMYD2
  - JMJD
  - HNMT
- Immunology & Inflammation
  - PD-1/PD-L1
  - COX
  - CCR
  - Histamine Receptor
  - IL Receptor
  - ROS
  - IDO/TDO
  - TLR
  - NOS
  - NADPH-oxidase
  - Leukotriene Receptor
  - MALT
  - CXCR
  - gp120/CD4
  - Nrf2
  - Immunology & Inflammation related
  - Prostaglandin Receptor
  - STING
  - Galectin
- Protein Tyrosine Kinase
  - VEGFR
  - EGFR
  - PDGFR
  - c-Met
  - HER2
  - IGF-1R
  - FLT3
  - FGFR
  - c-Kit
  - Src
  - ALK
  - Tie-2
  - c-RET
  - ACK
  - Axl
  - Ephrin Receptor
  - CSF-1R
  - Trk receptor
  - BTK
- Angiogenesis
  - VEGFR
  - JAK
  - EGFR
  - PDGFR
  - HER2
  - FLT3
  - FGFR
  - HIF
  - VDA
  - Bcr-Abl
  - Src
  - ALK
  - Syk
  - FAK
  - BTK
- Apoptosis
  - PD-1/PD-L1
  - Bcl-2
  - Caspase
  - p53
  - TNF-alpha
  - Mdm2
  - Survivin
  - c-RET
  - IAP
  - PERK
  - ASK
  - Serine/threonin kinase
  - Bcl-6
- Autophagy
  - Autophagy
  - CXCR
  - LRRK2
- ER stress & UPR
  - JNK
  - HSP e.g. HSP90
  - PERK
  - ASK
  - IRE1
  - PDI
- JAK/STAT
  - JAK
  - STAT
  - EGFR
  - Pim
- MAPK
  - MEK
  - Raf
  - p38 MAPK
  - JNK
  - TOPK
  - MNK
  - ERK
  - TAK1
  - Mixed Lineage Kinase
- Cytoskeletal Signaling
  - Akt
  - Wnt/beta-catenin
  - Bcr-Abl
  - PKC
  - FAK
  - HSP e.g. HSP90
  - Kinesin
  - Microtubule Associated
  - Integrin
  - PAK
  - Dynamin
- Cell Cycle
  - CDK
  - PD-1/PD-L1
  - Aurora Kinase
  - Chk
  - ROCK
  - PLK
  - APC
  - Wee1
  - Rho
  - c-Myc
  - DYRK
  - BMI-1
- TGF-beta/Smad
  - TGF-beta/Smad
  - Bcr-Abl
  - PKC
  - ROCK
- DNA Damage
  - HDAC
  - ATM/ATR
  - PARP
  - DNA/RNA Synthesis
  - Sirtuin
  - Topoisomerase
  - DNA-PK
  - Telomerase
  - MTH1
  - High-mobility Group
  - DNA alkylator
  - RAD51
  - CRISPR/Cas9
  - BMI-1
- Stem Cells & Wnt
- Ubiquitin
  - Proteasome
  - DUB
  - p97
  - SUMO
  - E2 conjugating
  - E1 Activating
  - E3 Ligase
- Neuronal Signaling
  - Beta Amyloid
  - 5-HT Receptor
  - COX
  - Gamma-secretase
  - GluR
  - Adrenergic Receptor
  - AChR
  - Histamine Receptor
  - Dopamine Receptor
  - Opioid Receptor
  - GABA Receptor
  - P-gp
  - P2 Receptor
  - OX Receptor
  - MT Receptor
  - GlyT
  - NMDAR
  - CaMK
  - Trk receptor
  - Substance P
  - BACE
- NF-κB
  - HDAC
  - NF-κB
  - IκB/IKK
  - NOD1
- GPCR & G Protein
- Endocrinology & Hormones
- Transmembrane Transporters
  - Calcium Channel
  - Sodium Channel
  - ATPase
  - Chloride Channel
  - Potassium Channel
  - GABA Receptor
  - P-gp
  - Proton Pump
  - CFTR
  - TRPV
  - CRM1
  - OCT
  - MCT
  - Amino acid transporter
- Metabolism
  - PPAR
  - P450 (e.g. CYP17)
  - HSP e.g. HSP90
  - PDE
  - Hydroxylase
  - Factor Xa
  - DHFR
  - Dehydrogenase
  - Procollagen C Proteinase
  - Phospholipase (e.g. PLA)
  - Carbonic Anhydrase
  - MAO
  - Liver X Receptor
  - FAAH
  - AhR
  - FXR
  - Vitamin
  - PKM
  - Ferroptosis
  - Thioredoxin
  - FOX
  - Lipoxygenase
  - HMG-CoA Reductase
  - Lipase
  - Fatty Acid Synthase
  - NAMPT
  - LDL
  - Casein Kinase
  - GLUT
  - CETP
  - IDO/TDO
  - Retinoid Receptor
  - Decarboxylase
  - Transferase
  - AdipoR
  - ATP-citrate lyase
  - Carbohydrate Metabolism
- Proteases
- Microbiology
- Others
  - Phosphorylase
  - Thrombin
  - PTEN
  - phosphatase
  - Others
- 产品类型
- Pfizer辉瑞授权化合物
- API
- 天然产物
- 抑制剂组合
- 多肽合成
- Eukaryotic Selection Antibiotics
- 所有靶点(A-Z)
- 所有产品(A-Z)
化合物分子库
动物实验抗体
新产品
联系我们

TOPK

抑制剂选择性比较

TOPK产品

所有产品 TOPK抑制剂(2)

产品目录

产品描述

文献引用

实验数据

S7652

OTS514 hydrochloride

OTS514是一种有效的TOPK抑制剂，IC50为2.6 nM.

Mol Imaging Biol, 2018, 10.1007/s11307-018-1288-6

S7648

OTS964

OTS964是一种有效的TOPK抑制剂，对TOPK具有高的亲和力和选择性，IC50为28 nM。

产品目录

产品描述

文献引用

实验数据

S7652

OTS514 hydrochloride

OTS514是一种有效的TOPK抑制剂，IC50为2.6 nM.

Mol Imaging Biol,2018, 10.1007/s11307-018-1288-6

S7648

OTS964

OTS964是一种有效的TOPK抑制剂，对TOPK具有高的亲和力和选择性，IC50为28 nM。

Tags: TOPK Inhibition | TOPK Inhibitor | TOPK activity | TOPK activation | TOPK phosphorylation