ADC Linker

抑制剂选择性比较

ADC Linker产品

目录号 产品描述 文献引用 实验数据
S0627

PDEC-NB

PDEC-NB 是一种二硫键可切割接头,可用于合成抗体药物偶联物 (ADC)。

S0671

Propargyl-PEG4-C2-acid

Propargyl-PEG5-acid is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can to used to synthesize ADC inhibitors of Galectin-3.

S6832

MC-VC-PAB-PNP

MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) 是一种可裂解组织蛋白酶的 ADC peptide linker,可用于合成抗体偶联药物(ADCs)。

S0620

DBCO-​C6-​acid

DBCO-C6-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be applied into the synthesis of carmaphycin analogues.

S3141

Maleimide

Maleimide 显示出荧光猝灭能力,并且可以作为荧光探针用于硫醇分析物的特异性检测。Maleimide 还用于生产抗体偶联药物(ADC),用于癌症研究。

S0091

Fmoc-Val-Ala-PAB

Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) 是一种有用且可裂解的linker,可用于制备用于靶向药物递送的 Antibody-Drug-Conjugation (ADC) 抗体偶联药物。

S9795New

Deruxtecan

Deruxtecan是一种 ADC 药物-接头偶联物,由可切割的甘氨酸-甘氨酸-苯丙氨酸-甘氨酸四肽基接头、自我牺牲氨基亚甲基间隔物和新型拓扑异构酶 1 抑制剂有效载荷组成,它是 exatecan (DX-8951) 的衍生物。

S0335

Boc-Val-Cit-PAB-PNP

Boc-Val-Cit-PAB-PNP 是一种可裂解的ADC linker,用于抗体偶联药物 (ADCs)的合成。

S0564

SPDP

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with cysteine sulfhydryls. SPDP is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

S0565

DBCO-NHS ester

DBCO-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0566

Sulfo-SMCC sodium

Sulfo-SMCC sodium is a commonly-used hetero-bifunctional, noncleavable ADC crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

S0567

Amino-PEG4-alcohol

Amino-PEG4-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. Amino-PEG4-alcohol is a non-cleavable 4-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

S0568

DBCO-acid

DBCO-acid is a cleavable ADC linker applied into the synthesis of ADC linker DBCO-NHS ester and drug-linker conjugates DBCO-PEG-MMAE.

S0569

Fmoc-8-amino-3,6-dioxaoctanoic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0570

Boc-NH-C6-Br

Boc-NH-C6-Br is a cleavable linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0571

SPDB

SPDB is a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugate (ADCs).

S0572

SMCC

SMCC (Succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate) 是一种杂双功能交联剂,包含 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,允许含胺和巯基的分子共价结合。SMCC 结合的抗原偶联脾细胞以诱导抗原特异性免疫反应。

S0573

N-Hydroxysulfosuccinimide sodium

N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0574

Fmoc-NH-PEG4-CH2CH2COOH

Fmoc-NH-PEG4-CH2CH2COOH (Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0575

Boc-NH-PEG4-CH2CH2NH2

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0576

NH2-PEG2-C2-Boc

NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG2-C2-Boc is a non-cleavable 2-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

S0577

6-Maleimidohexanoic acid N-hydroxysuccinimide ester

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (ECMS) is a useful protective group in antibody drug conjugates (ADCs).

S0578

Hydroxy-PEG4-(CH2)2-Boc

Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0579

Boc-Gly-Gly-Phe-Gly-OH

Boc-Gly-Gly-Phe-Gly-OH (GGFG) is a self-assembly of N- and C-protected tetrapeptide, a protease cleavable linker used for the antibody-drug conjugates (ADCs).

S0580

N-Boc-diethanolamine

N-Boc-diethanolamine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0582

BMPS

BMPS is a noncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0583

Hydroxy-PEG3-(CH2)2-Boc

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0584

Fmoc-NH-PEG1-CH2COOH

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0585

Boc-Val-Cit-OH

Boc-Val-Cit-OH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0586

Succinic anhydride

Succinic anhydride (SA, Succinyl Oxide, Butanedioic Anhydride) 是一种环状酸酐,可用于纤维素的均相化学改性,并用作不可裂解的ADC接头,可与其他化合物反应以将前药连接至靶向多肽的胺或羟基1组。

S0587

Mal-amido-PEG8-C2-acid

Mal-amido-PEG8-C2-acid is a noncleavable ADC linker.

S0588

Propargyl-PEG6-acid

Propargyl-PEG6-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0589

Mal-PEG3-NHS ester

Mal-PEG3-NHS ester is a noncleavable ADC linker with a Maleimide group that is used for making antibody-drug conjugates (ADCs).

S0590

Propargyl-PEG5-amine

Propargyl-PEG5-amine is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker applied into the synthesis of PROTACs.

S0591

Propargyl-PEG1-NHS ester

Propargyl-PEG1-NHS ester is a noncleavable 1-unit PEG linker that can be used in antibody-drug-conjugation (ADC).

S0592

NH-bis(C1-Boc)

NH-bis(C1-Boc) is an uncleavable linker that can be used for antibody-drug conjugates (ADCs).

S0593

Amino-PEG4-CH2COOH

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0594

Azido-PEG7-amine

Azido-PEG7-amine is a non-cleavable 7-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0595

Hydroxy-PEG2-(CH2)2-Boc

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0596

Amino-PEG8-Boc

Amino-PEG8-Boc is a cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0597

m-PEG6-NHS ester

m-PEG6-NHS ester is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0598

Mal-PEG2-acid

Mal-PEG2-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin and its derivative cytotoxic molecule.

S0599

m-PEG7-CH2COOH

m-PEG7-CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0600

Phe-Lys(Trt)-PAB

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker that can be used for the antibody-drug conjugates (ADCs).

S0601

N3-PEG2-C2-NHS ester

N3-PEG2-C2-NHS ester is a noncleavable 2-unit PEG linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0602

Ald-Ph-NHS ester

Ald-Ph-NHS ester is an uncleavable linker for antibody-drug-conjugation (ADC).

S0603

m-PEG12-amine

m-PEG12-amine 是一种基于PEG的 PROTAC linker,可用于PROTAC的合成。m-PEG12-amine 也是一种不可裂解的12个单元的PEG ADC linker,可用于抗体偶联药物(ADCs)的合成。

S0604

m-PEG11-Amine

m-PEG11-Amino is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0605

Azido-PEG4-CH2-Boc

Azido-PEG4-CH2-Boc is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0606

Fmoc-NH-PEG3-CH2CH2COOH

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0607

Fmoc-NH-PEG2-CH2CH2COOH

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0608

Fmoc-NH-PEG6-CH2CH2COOH

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0609

SPDV

SPDV is a cleavable ADC linker that can be applied into the diagnosis and treatment of cancer or B cell proliferative disease.

S0610

SPDB-sulfo

SPDB-sulfo is a glutathione cleavable ADC linker applied into the synthesis the antibody-drug conjugates (ADCs).

S0612

Propargyl-PEG7-acid

Propargyl-PEG7-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0613

Bis-​PEG4-​NHS ester

Bis-​PEG4-​NHS ester is a noncleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).

S0616

Azido-PEG2-C2-amine

Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG2-C2-amine is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0618

N-Boc-PEG2-bromide

N-Boc-PEG2-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0621

Tr-PEG5-OH

Tr-PEG5-OH is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0622

m-PEG4-Br

m-PEG4-Br is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency.

S0623

Bis-PEG1-NHS ester

Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker for antibody-drug-conjugation (ADC).

S0625

m-PEG7-Amine

m-PEG7-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0626

DSP Crosslinker

DSP Crosslinker 是一种可裂解的 ADC linker,可用于抗体-药物偶联物(ADC)的合成。

S0629

Ald-Ph-amido-PEG4-C2-NHS ester

Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).

S0630

Mal-PEG6-NHS ester

Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

S0631

Fmoc-NH-PEG4-CH2COOH

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0632

SIA Crosslinker

SIA Crosslinker is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0633

Ald-Ph-amido-PEG4-C2-acid

Ald-Ph-amido-PEG4-C2-acid is a non-cleavable linker used for the antibody-drug conjugates (ADCs).

S0634

Propargyl-PEG8-acid

Propargyl-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). The ADCs can be applied into bacterial infections caused by Gram-negative bacteria.

S0635

DBCO-amine

DBCO-amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0638

Bis-​PEG2-​NHS ester

Bis-PEG2-NHS ester is a non-cleavable 2-unit PEG linker used for antibody-drug-conjugation (ADC).

S0639

m-PEG2-Amine

m-PEG2-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0640

NH2-PEG5-OH

NH2-PEG5-OH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0641

Mal-amido-PEG2-NHS ester

Mal-amido-PEG2-NHS ester is a non-cleavable ADC linker containing a maleimide group and an NHS ester. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

S0642

Azido-PEG6-amine

Azido-PEG6-amine is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0643

4-N3Pfp-NHS ester

4-N3Pfp-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0644

Mal-C2-NHS ester

Mal-C2-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0645

NHPI-PEG4-C2-NHS ester

NHPI-PEG4-C2-NHS ester is used as a linker for antibody-drug conjugates (ADCs).

S0647

Propargyl-PEG8-NH2

Propargyl-PEG8-NH2 is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0648

Fmoc-Asp-NH2

Fmoc-Asp-NH2 is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0649

Fmoc-NH-PEG8-CH2CH2COOH

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0650

m-PEG3-CH2CH2COOH

m-PEG3-CH2CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0651

N-Butanoyl-L-homoserine lactone

N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) 是一种可切割的ADC接头,用于合成抗体药物偶联物(ADC)。N-Butyryl-L-homoserine lactone是一种小的可扩散信号分子,参与群体感应、控制基因表达和细胞代谢。

S0652

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0653

m-PEG9-Amine

m-PEG9-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0654

Mal-​PEG4-​NHS ester

Mal-PEG4-NHS ester 是一种不可切割的 ADC 接头(ADC linker),包含一个马来酰亚胺基团、4 单元 PEG 和一个 NHS 酯。

S0655

Propargyl-PEG4-NHS ester

Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker used for antibody-drug-conjugations (ADCs).

S0656

Azido-PEG9-acid

Azido-PEG9-acid is a non-cleavable 9-unit PEG ADC linker applied in the synthesis of antibody-drug conjugates (ADCs).

S0657

DSS Crosslinker

DSS Crosslinker (Disuccinimidyl suberate) 是一种膜可渗透的同双功能交联剂,也是一种不可裂解的ADC linker,可用于抗体药物偶联药物(ADCs)的合成。

S0658

LC-PEG8-SPDP

LC-PEG8-SPDP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0662

m-PEG8-Amine

m-PEG8-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0664

m-PEG10-alcohol

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0665

m-PEG2-Tos

m-PEG2-Tos is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0667

m-PEG3-Amine

m-PEG3-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0668

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0669

Amino-PEG2-C2-acid

Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0670

N3-PEG3-CH2CH2-Boc

N3-PEG3-CH2CH2-Boc is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0672

AMAS

AMAS is a non-cleavable heterobifunctional crosslinker with an NHS ester and maleimide groups. AMAS allows covalent conjugation of amine- and sulfhydryl-containing molecules.

S0673

Propargyl-C2-NHS ester

Propargyl-C2-NHS ester is a non-cleavable linker used for antibody-drug-conjugation (ADC).

S0674

Amino-PEG3-C2-acid

Amino-PEG3-C2-acid is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0675

Azide-PEG5-Tos

Azide-PEG5-Tos (Azido-PEG5-OTs) 是一种可裂解的5-unit PEG ADC linker,应用于抗体-药物偶联物(ADCs)的合成。

S0676

m-PEG6-Amine

m-PEG6-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0677

Fmoc-Phe-Lys(Trt)-PAB-PNP

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0678

BnO-PEG6-OH

BnO-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0680

PDP-C1-Ph-Val-Cit

PDP-C1-Ph-Val-Cit is a cleavable ADC linker that can be used for antibody-drug conjugates (ADCs).

S0681

Amino-PEG6-alcohol

Amino-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0683

Aminoethyl-SS-ethylalcohol

Aminoethyl-SS-ethylalcohol is an Alkyl-Chain-based PROTAC linker can be applied into the synthesis of PROTACs. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0684

Propargyl-PEG4-Tos

Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0685

Propargyl-PEG2-acid

Propargyl-PEG2-acid is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0686

NH2-PEG4-CH2CH2COOH

NH2-PEG4-CH2CH2COOH is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0687

NH2-PEG6-Boc

NH2-PEG6-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0688

m-PEG8-NHS ester

m-PEG8-NHS ester is a non-cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0689

Bis-PEG8-acid

Bis-PEG8-acid is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0691

N-Boc-PEG4-bromide

N-Boc-PEG4-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0692

N3-Ph-NHS ester

N3-Ph-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0693

Bis-PEG3-NHS ester

Bis-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used for antibody-drug-conjugation (ADC).

S0694

Bis-PEG5-NHS ester

Bis-PEG5-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0695

5-Maleimidovaleric acid

5-Maleimidovaleric acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0696

Propargyl-PEG2-NHBoc

Propargyl-PEG2-NHBoc is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs.

S0697

Mal-PEG2-NHS ester

Mal-PEG2-NHS ester is a non-cleavable ADC linker consists of a Maleimide group, 2-unit PEG and an NHS ester.

S0698

Boc-NH-PEG4-CH2CH2COOH

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be applied into the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

S0700

GMBS

GMBS is a cross-linker with heterobifunction.

S2982

DM1-SMCC

DM1-SMCC (SMCC-DM1) 是一种 抗体药物偶联物 (ADC)-接头 (antibody drug conjugate (ADC)-linker),由有效的微管破坏剂 DM1 和接头 SMCC 组成。

目录号 产品描述 文献引用 实验数据
S0627

PDEC-NB

PDEC-NB 是一种二硫键可切割接头,可用于合成抗体药物偶联物 (ADC)。

目录号 产品描述 文献引用 实验数据
S0671

Propargyl-PEG4-C2-acid

Propargyl-PEG5-acid is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can to used to synthesize ADC inhibitors of Galectin-3.

目录号 产品描述 文献引用 实验数据
S6832

MC-VC-PAB-PNP

MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) 是一种可裂解组织蛋白酶的 ADC peptide linker,可用于合成抗体偶联药物(ADCs)。

S0620

DBCO-​C6-​acid

DBCO-C6-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be applied into the synthesis of carmaphycin analogues.

S3141

Maleimide

Maleimide 显示出荧光猝灭能力,并且可以作为荧光探针用于硫醇分析物的特异性检测。Maleimide 还用于生产抗体偶联药物(ADC),用于癌症研究。

S0091

Fmoc-Val-Ala-PAB

Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) 是一种有用且可裂解的linker,可用于制备用于靶向药物递送的 Antibody-Drug-Conjugation (ADC) 抗体偶联药物。

S9795New

Deruxtecan

Deruxtecan是一种 ADC 药物-接头偶联物,由可切割的甘氨酸-甘氨酸-苯丙氨酸-甘氨酸四肽基接头、自我牺牲氨基亚甲基间隔物和新型拓扑异构酶 1 抑制剂有效载荷组成,它是 exatecan (DX-8951) 的衍生物。

S0335

Boc-Val-Cit-PAB-PNP

Boc-Val-Cit-PAB-PNP 是一种可裂解的ADC linker,用于抗体偶联药物 (ADCs)的合成。

S0564

SPDP

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with cysteine sulfhydryls. SPDP is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

S0565

DBCO-NHS ester

DBCO-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0566

Sulfo-SMCC sodium

Sulfo-SMCC sodium is a commonly-used hetero-bifunctional, noncleavable ADC crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

S0567

Amino-PEG4-alcohol

Amino-PEG4-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. Amino-PEG4-alcohol is a non-cleavable 4-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

S0568

DBCO-acid

DBCO-acid is a cleavable ADC linker applied into the synthesis of ADC linker DBCO-NHS ester and drug-linker conjugates DBCO-PEG-MMAE.

S0569

Fmoc-8-amino-3,6-dioxaoctanoic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0570

Boc-NH-C6-Br

Boc-NH-C6-Br is a cleavable linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0571

SPDB

SPDB is a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugate (ADCs).

S0572

SMCC

SMCC (Succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate) 是一种杂双功能交联剂,包含 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,允许含胺和巯基的分子共价结合。SMCC 结合的抗原偶联脾细胞以诱导抗原特异性免疫反应。

S0573

N-Hydroxysulfosuccinimide sodium

N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0574

Fmoc-NH-PEG4-CH2CH2COOH

Fmoc-NH-PEG4-CH2CH2COOH (Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0575

Boc-NH-PEG4-CH2CH2NH2

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0576

NH2-PEG2-C2-Boc

NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG2-C2-Boc is a non-cleavable 2-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

S0577

6-Maleimidohexanoic acid N-hydroxysuccinimide ester

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (ECMS) is a useful protective group in antibody drug conjugates (ADCs).

S0578

Hydroxy-PEG4-(CH2)2-Boc

Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0579

Boc-Gly-Gly-Phe-Gly-OH

Boc-Gly-Gly-Phe-Gly-OH (GGFG) is a self-assembly of N- and C-protected tetrapeptide, a protease cleavable linker used for the antibody-drug conjugates (ADCs).

S0580

N-Boc-diethanolamine

N-Boc-diethanolamine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0582

BMPS

BMPS is a noncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0583

Hydroxy-PEG3-(CH2)2-Boc

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0584

Fmoc-NH-PEG1-CH2COOH

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0585

Boc-Val-Cit-OH

Boc-Val-Cit-OH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0586

Succinic anhydride

Succinic anhydride (SA, Succinyl Oxide, Butanedioic Anhydride) 是一种环状酸酐,可用于纤维素的均相化学改性,并用作不可裂解的ADC接头,可与其他化合物反应以将前药连接至靶向多肽的胺或羟基1组。

S0587

Mal-amido-PEG8-C2-acid

Mal-amido-PEG8-C2-acid is a noncleavable ADC linker.

S0588

Propargyl-PEG6-acid

Propargyl-PEG6-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0589

Mal-PEG3-NHS ester

Mal-PEG3-NHS ester is a noncleavable ADC linker with a Maleimide group that is used for making antibody-drug conjugates (ADCs).

S0590

Propargyl-PEG5-amine

Propargyl-PEG5-amine is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker applied into the synthesis of PROTACs.

S0591

Propargyl-PEG1-NHS ester

Propargyl-PEG1-NHS ester is a noncleavable 1-unit PEG linker that can be used in antibody-drug-conjugation (ADC).

S0592

NH-bis(C1-Boc)

NH-bis(C1-Boc) is an uncleavable linker that can be used for antibody-drug conjugates (ADCs).

S0593

Amino-PEG4-CH2COOH

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0594

Azido-PEG7-amine

Azido-PEG7-amine is a non-cleavable 7-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0595

Hydroxy-PEG2-(CH2)2-Boc

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0596

Amino-PEG8-Boc

Amino-PEG8-Boc is a cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0597

m-PEG6-NHS ester

m-PEG6-NHS ester is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0598

Mal-PEG2-acid

Mal-PEG2-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin and its derivative cytotoxic molecule.

S0599

m-PEG7-CH2COOH

m-PEG7-CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0600

Phe-Lys(Trt)-PAB

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker that can be used for the antibody-drug conjugates (ADCs).

S0601

N3-PEG2-C2-NHS ester

N3-PEG2-C2-NHS ester is a noncleavable 2-unit PEG linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0602

Ald-Ph-NHS ester

Ald-Ph-NHS ester is an uncleavable linker for antibody-drug-conjugation (ADC).

S0603

m-PEG12-amine

m-PEG12-amine 是一种基于PEG的 PROTAC linker,可用于PROTAC的合成。m-PEG12-amine 也是一种不可裂解的12个单元的PEG ADC linker,可用于抗体偶联药物(ADCs)的合成。

S0604

m-PEG11-Amine

m-PEG11-Amino is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0605

Azido-PEG4-CH2-Boc

Azido-PEG4-CH2-Boc is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0606

Fmoc-NH-PEG3-CH2CH2COOH

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0607

Fmoc-NH-PEG2-CH2CH2COOH

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0608

Fmoc-NH-PEG6-CH2CH2COOH

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0609

SPDV

SPDV is a cleavable ADC linker that can be applied into the diagnosis and treatment of cancer or B cell proliferative disease.

S0610

SPDB-sulfo

SPDB-sulfo is a glutathione cleavable ADC linker applied into the synthesis the antibody-drug conjugates (ADCs).

S0612

Propargyl-PEG7-acid

Propargyl-PEG7-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0613

Bis-​PEG4-​NHS ester

Bis-​PEG4-​NHS ester is a noncleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).

S0616

Azido-PEG2-C2-amine

Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG2-C2-amine is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0618

N-Boc-PEG2-bromide

N-Boc-PEG2-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0621

Tr-PEG5-OH

Tr-PEG5-OH is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0622

m-PEG4-Br

m-PEG4-Br is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency.

S0623

Bis-PEG1-NHS ester

Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker for antibody-drug-conjugation (ADC).

S0625

m-PEG7-Amine

m-PEG7-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0626

DSP Crosslinker

DSP Crosslinker 是一种可裂解的 ADC linker,可用于抗体-药物偶联物(ADC)的合成。

S0629

Ald-Ph-amido-PEG4-C2-NHS ester

Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).

S0630

Mal-PEG6-NHS ester

Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

S0631

Fmoc-NH-PEG4-CH2COOH

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0632

SIA Crosslinker

SIA Crosslinker is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0633

Ald-Ph-amido-PEG4-C2-acid

Ald-Ph-amido-PEG4-C2-acid is a non-cleavable linker used for the antibody-drug conjugates (ADCs).

S0634

Propargyl-PEG8-acid

Propargyl-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). The ADCs can be applied into bacterial infections caused by Gram-negative bacteria.

S0635

DBCO-amine

DBCO-amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0638

Bis-​PEG2-​NHS ester

Bis-PEG2-NHS ester is a non-cleavable 2-unit PEG linker used for antibody-drug-conjugation (ADC).

S0639

m-PEG2-Amine

m-PEG2-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0640

NH2-PEG5-OH

NH2-PEG5-OH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0641

Mal-amido-PEG2-NHS ester

Mal-amido-PEG2-NHS ester is a non-cleavable ADC linker containing a maleimide group and an NHS ester. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

S0642

Azido-PEG6-amine

Azido-PEG6-amine is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0643

4-N3Pfp-NHS ester

4-N3Pfp-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0644

Mal-C2-NHS ester

Mal-C2-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0645

NHPI-PEG4-C2-NHS ester

NHPI-PEG4-C2-NHS ester is used as a linker for antibody-drug conjugates (ADCs).

S0647

Propargyl-PEG8-NH2

Propargyl-PEG8-NH2 is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0648

Fmoc-Asp-NH2

Fmoc-Asp-NH2 is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0649

Fmoc-NH-PEG8-CH2CH2COOH

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0650

m-PEG3-CH2CH2COOH

m-PEG3-CH2CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0651

N-Butanoyl-L-homoserine lactone

N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) 是一种可切割的ADC接头,用于合成抗体药物偶联物(ADC)。N-Butyryl-L-homoserine lactone是一种小的可扩散信号分子,参与群体感应、控制基因表达和细胞代谢。

S0652

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0653

m-PEG9-Amine

m-PEG9-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0654

Mal-​PEG4-​NHS ester

Mal-PEG4-NHS ester 是一种不可切割的 ADC 接头(ADC linker),包含一个马来酰亚胺基团、4 单元 PEG 和一个 NHS 酯。

S0655

Propargyl-PEG4-NHS ester

Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker used for antibody-drug-conjugations (ADCs).

S0656

Azido-PEG9-acid

Azido-PEG9-acid is a non-cleavable 9-unit PEG ADC linker applied in the synthesis of antibody-drug conjugates (ADCs).

S0657

DSS Crosslinker

DSS Crosslinker (Disuccinimidyl suberate) 是一种膜可渗透的同双功能交联剂,也是一种不可裂解的ADC linker,可用于抗体药物偶联药物(ADCs)的合成。

S0658

LC-PEG8-SPDP

LC-PEG8-SPDP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0662

m-PEG8-Amine

m-PEG8-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0664

m-PEG10-alcohol

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0665

m-PEG2-Tos

m-PEG2-Tos is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0667

m-PEG3-Amine

m-PEG3-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0668

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0669

Amino-PEG2-C2-acid

Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0670

N3-PEG3-CH2CH2-Boc

N3-PEG3-CH2CH2-Boc is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.

S0672

AMAS

AMAS is a non-cleavable heterobifunctional crosslinker with an NHS ester and maleimide groups. AMAS allows covalent conjugation of amine- and sulfhydryl-containing molecules.

S0673

Propargyl-C2-NHS ester

Propargyl-C2-NHS ester is a non-cleavable linker used for antibody-drug-conjugation (ADC).

S0674

Amino-PEG3-C2-acid

Amino-PEG3-C2-acid is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0675

Azide-PEG5-Tos

Azide-PEG5-Tos (Azido-PEG5-OTs) 是一种可裂解的5-unit PEG ADC linker,应用于抗体-药物偶联物(ADCs)的合成。

S0676

m-PEG6-Amine

m-PEG6-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0677

Fmoc-Phe-Lys(Trt)-PAB-PNP

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0678

BnO-PEG6-OH

BnO-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0680

PDP-C1-Ph-Val-Cit

PDP-C1-Ph-Val-Cit is a cleavable ADC linker that can be used for antibody-drug conjugates (ADCs).

S0681

Amino-PEG6-alcohol

Amino-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0683

Aminoethyl-SS-ethylalcohol

Aminoethyl-SS-ethylalcohol is an Alkyl-Chain-based PROTAC linker can be applied into the synthesis of PROTACs. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0684

Propargyl-PEG4-Tos

Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0685

Propargyl-PEG2-acid

Propargyl-PEG2-acid is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0686

NH2-PEG4-CH2CH2COOH

NH2-PEG4-CH2CH2COOH is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0687

NH2-PEG6-Boc

NH2-PEG6-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0688

m-PEG8-NHS ester

m-PEG8-NHS ester is a non-cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0689

Bis-PEG8-acid

Bis-PEG8-acid is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0691

N-Boc-PEG4-bromide

N-Boc-PEG4-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0692

N3-Ph-NHS ester

N3-Ph-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0693

Bis-PEG3-NHS ester

Bis-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used for antibody-drug-conjugation (ADC).

S0694

Bis-PEG5-NHS ester

Bis-PEG5-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0695

5-Maleimidovaleric acid

5-Maleimidovaleric acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

S0696

Propargyl-PEG2-NHBoc

Propargyl-PEG2-NHBoc is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs.

S0697

Mal-PEG2-NHS ester

Mal-PEG2-NHS ester is a non-cleavable ADC linker consists of a Maleimide group, 2-unit PEG and an NHS ester.

S0698

Boc-NH-PEG4-CH2CH2COOH

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be applied into the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

S0700

GMBS

GMBS is a cross-linker with heterobifunction.

S2982

DM1-SMCC

DM1-SMCC (SMCC-DM1) 是一种 抗体药物偶联物 (ADC)-接头 (antibody drug conjugate (ADC)-linker),由有效的微管破坏剂 DM1 和接头 SMCC 组成。