ADC Linker

ADC Linker抑制剂选择性比较

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目录号 产品名 产品描述 文献引用 实验数据
S0627 PDEC-NB PDEC-NB 是一种二硫键可切割接头,可用于合成抗体药物偶联物 (ADC)。
S0671 Propargyl-PEG4-C2-acid Propargyl-PEG5-acid is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can to used to synthesize ADC inhibitors of Galectin-3.
S6832 MC-VC-PAB-PNP MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) 是一种可裂解组织蛋白酶的 ADC peptide linker,可用于合成抗体偶联药物(ADCs)。
S0620 DBCO-​C6-​acid DBCO-C6-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be applied into the synthesis of carmaphycin analogues.
S3141 Maleimide Maleimide 显示出荧光猝灭能力,并且可以作为荧光探针用于硫醇分析物的特异性检测。Maleimide 还用于生产抗体偶联药物(ADC),用于癌症研究。
S0091 Fmoc-Val-Ala-PAB Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) 是一种有用且可裂解的linker,可用于制备用于靶向药物递送的 Antibody-Drug-Conjugation (ADC) 抗体偶联药物。
S9795New Deruxtecan Deruxtecan是一种 ADC 药物-接头偶联物,由可切割的甘氨酸-甘氨酸-苯丙氨酸-甘氨酸四肽基接头、自我牺牲氨基亚甲基间隔物和新型拓扑异构酶 1 抑制剂有效载荷组成,它是 exatecan (DX-8951) 的衍生物。
S0335 Boc-Val-Cit-PAB-PNP Boc-Val-Cit-PAB-PNP 是一种可裂解的ADC linker,用于抗体偶联药物 (ADCs)的合成。
S0564 SPDP SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with cysteine sulfhydryls. SPDP is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
S0565 DBCO-NHS ester DBCO-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0566 Sulfo-SMCC sodium Sulfo-SMCC sodium is a commonly-used hetero-bifunctional, noncleavable ADC crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
S0567 Amino-PEG4-alcohol Amino-PEG4-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. Amino-PEG4-alcohol is a non-cleavable 4-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
S0568 DBCO-acid DBCO-acid is a cleavable ADC linker applied into the synthesis of ADC linker DBCO-NHS ester and drug-linker conjugates DBCO-PEG-MMAE.
S0569 Fmoc-8-amino-3,6-dioxaoctanoic acid Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0570 Boc-NH-C6-Br Boc-NH-C6-Br is a cleavable linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0571 SPDB SPDB is a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugate (ADCs).
S0572 SMCC SMCC (Succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate) 是一种杂双功能交联剂,包含 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,允许含胺和巯基的分子共价结合。SMCC 结合的抗原偶联脾细胞以诱导抗原特异性免疫反应。
S0573 N-Hydroxysulfosuccinimide sodium N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0574 Fmoc-NH-PEG4-CH2CH2COOH Fmoc-NH-PEG4-CH2CH2COOH (Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0575 Boc-NH-PEG4-CH2CH2NH2 Boc-NH-PEG4-CH2CH2NH2 a cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0576 NH2-PEG2-C2-Boc NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG2-C2-Boc is a non-cleavable 2-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
S0577 6-Maleimidohexanoic acid N-hydroxysuccinimide ester 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (ECMS) is a useful protective group in antibody drug conjugates (ADCs).
S0578 Hydroxy-PEG4-(CH2)2-Boc Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0579 Boc-Gly-Gly-Phe-Gly-OH Boc-Gly-Gly-Phe-Gly-OH (GGFG) is a self-assembly of N- and C-protected tetrapeptide, a protease cleavable linker used for the antibody-drug conjugates (ADCs).
S0580 N-Boc-diethanolamine N-Boc-diethanolamine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0582 BMPS BMPS is a noncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0583 Hydroxy-PEG3-(CH2)2-Boc Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0584 Fmoc-NH-PEG1-CH2COOH Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0585 Boc-Val-Cit-OH Boc-Val-Cit-OH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0586 Succinic anhydride Succinic anhydride (SA, Succinyl Oxide, Butanedioic Anhydride) 是一种环状酸酐,可用于纤维素的均相化学改性,并用作不可裂解的ADC接头,可与其他化合物反应以将前药连接至靶向多肽的胺或羟基1组。
S0587 Mal-amido-PEG8-C2-acid Mal-amido-PEG8-C2-acid is a noncleavable ADC linker.
S0588 Propargyl-PEG6-acid Propargyl-PEG6-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0589 Mal-PEG3-NHS ester Mal-PEG3-NHS ester is a noncleavable ADC linker with a Maleimide group that is used for making antibody-drug conjugates (ADCs).
S0590 Propargyl-PEG5-amine Propargyl-PEG5-amine is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker applied into the synthesis of PROTACs.
S0591 Propargyl-PEG1-NHS ester Propargyl-PEG1-NHS ester is a noncleavable 1-unit PEG linker that can be used in antibody-drug-conjugation (ADC).
S0592 NH-bis(C1-Boc) NH-bis(C1-Boc) is an uncleavable linker that can be used for antibody-drug conjugates (ADCs).
S0593 Amino-PEG4-CH2COOH Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0594 Azido-PEG7-amine Azido-PEG7-amine is a non-cleavable 7-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0595 Hydroxy-PEG2-(CH2)2-Boc Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0596 Amino-PEG8-Boc Amino-PEG8-Boc is a cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0597 m-PEG6-NHS ester m-PEG6-NHS ester is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0598 Mal-PEG2-acid Mal-PEG2-acid is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin and its derivative cytotoxic molecule.
S0599 m-PEG7-CH2COOH m-PEG7-CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0600 Phe-Lys(Trt)-PAB Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker that can be used for the antibody-drug conjugates (ADCs).
S0601 N3-PEG2-C2-NHS ester N3-PEG2-C2-NHS ester is a noncleavable 2-unit PEG linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0602 Ald-Ph-NHS ester Ald-Ph-NHS ester is an uncleavable linker for antibody-drug-conjugation (ADC).
S0603 m-PEG12-amine m-PEG12-amine 是一种基于PEG的 PROTAC linker,可用于PROTAC的合成。m-PEG12-amine 也是一种不可裂解的12个单元的PEG ADC linker,可用于抗体偶联药物(ADCs)的合成。
S0604 m-PEG11-Amine m-PEG11-Amino is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0605 Azido-PEG4-CH2-Boc Azido-PEG4-CH2-Boc is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.
S0606 Fmoc-NH-PEG3-CH2CH2COOH Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0607 Fmoc-NH-PEG2-CH2CH2COOH Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0608 Fmoc-NH-PEG6-CH2CH2COOH Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0609 SPDV SPDV is a cleavable ADC linker that can be applied into the diagnosis and treatment of cancer or B cell proliferative disease.
S0610 SPDB-sulfo SPDB-sulfo is a glutathione cleavable ADC linker applied into the synthesis the antibody-drug conjugates (ADCs).
S0612 Propargyl-PEG7-acid Propargyl-PEG7-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0613 Bis-​PEG4-​NHS ester Bis-​PEG4-​NHS ester is a noncleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).
S0616 Azido-PEG2-C2-amine Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG2-C2-amine is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0618 N-Boc-PEG2-bromide N-Boc-PEG2-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0621 Tr-PEG5-OH Tr-PEG5-OH is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0622 m-PEG4-Br m-PEG4-Br is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency.
S0623 Bis-PEG1-NHS ester Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker for antibody-drug-conjugation (ADC).
S0625 m-PEG7-Amine m-PEG7-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0626 DSP Crosslinker DSP Crosslinker 是一种可裂解的 ADC linker,可用于抗体-药物偶联物(ADC)的合成。
S0629 Ald-Ph-amido-PEG4-C2-NHS ester Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker for antibody-drug-conjugation (ADC).
S0630 Mal-PEG6-NHS ester Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
S0631 Fmoc-NH-PEG4-CH2COOH Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0632 SIA Crosslinker SIA Crosslinker is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0633 Ald-Ph-amido-PEG4-C2-acid Ald-Ph-amido-PEG4-C2-acid is a non-cleavable linker used for the antibody-drug conjugates (ADCs).
S0634 Propargyl-PEG8-acid Propargyl-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). The ADCs can be applied into bacterial infections caused by Gram-negative bacteria.
S0635 DBCO-amine DBCO-amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0638 Bis-​PEG2-​NHS ester Bis-PEG2-NHS ester is a non-cleavable 2-unit PEG linker used for antibody-drug-conjugation (ADC).
S0639 m-PEG2-Amine m-PEG2-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0640 NH2-PEG5-OH NH2-PEG5-OH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0641 Mal-amido-PEG2-NHS ester Mal-amido-PEG2-NHS ester is a non-cleavable ADC linker containing a maleimide group and an NHS ester. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
S0642 Azido-PEG6-amine Azido-PEG6-amine is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0643 4-N3Pfp-NHS ester 4-N3Pfp-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0644 Mal-C2-NHS ester Mal-C2-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0645 NHPI-PEG4-C2-NHS ester NHPI-PEG4-C2-NHS ester is used as a linker for antibody-drug conjugates (ADCs).
S0647 Propargyl-PEG8-NH2 Propargyl-PEG8-NH2 is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0648 Fmoc-Asp-NH2 Fmoc-Asp-NH2 is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0649 Fmoc-NH-PEG8-CH2CH2COOH Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0650 m-PEG3-CH2CH2COOH m-PEG3-CH2CH2COOH is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0651 N-Butanoyl-L-homoserine lactone N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) 是一种可切割的ADC接头,用于合成抗体药物偶联物(ADC)。N-Butyryl-L-homoserine lactone是一种小的可扩散信号分子,参与群体感应、控制基因表达和细胞代谢。
S0652 Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0653 m-PEG9-Amine m-PEG9-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0654 Mal-​PEG4-​NHS ester Mal-PEG4-NHS ester 是一种不可切割的 ADC 接头(ADC linker),包含一个马来酰亚胺基团、4 单元 PEG 和一个 NHS 酯。
S0655 Propargyl-PEG4-NHS ester Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker used for antibody-drug-conjugations (ADCs).
S0656 Azido-PEG9-acid Azido-PEG9-acid is a non-cleavable 9-unit PEG ADC linker applied in the synthesis of antibody-drug conjugates (ADCs).
S0657 DSS Crosslinker DSS Crosslinker (Disuccinimidyl suberate) 是一种膜可渗透的同双功能交联剂,也是一种不可裂解的ADC linker,可用于抗体药物偶联药物(ADCs)的合成。
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S0658 LC-PEG8-SPDP LC-PEG8-SPDP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0662 m-PEG8-Amine m-PEG8-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0664 m-PEG10-alcohol m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.
S0665 m-PEG2-Tos m-PEG2-Tos is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0667 m-PEG3-Amine m-PEG3-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0668 Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs.
S0669 Amino-PEG2-C2-acid Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0670 N3-PEG3-CH2CH2-Boc N3-PEG3-CH2CH2-Boc is a cleavable 3-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.
S0672 AMAS AMAS is a non-cleavable heterobifunctional crosslinker with an NHS ester and maleimide groups. AMAS allows covalent conjugation of amine- and sulfhydryl-containing molecules.
S0673 Propargyl-C2-NHS ester Propargyl-C2-NHS ester is a non-cleavable linker used for antibody-drug-conjugation (ADC).
S0674 Amino-PEG3-C2-acid Amino-PEG3-C2-acid is a cleavable PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0675 Azide-PEG5-Tos Azide-PEG5-Tos (Azido-PEG5-OTs) 是一种可裂解的5-unit PEG ADC linker,应用于抗体-药物偶联物(ADCs)的合成。
S0676 m-PEG6-Amine m-PEG6-Amine is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0677 Fmoc-Phe-Lys(Trt)-PAB-PNP Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0678 BnO-PEG6-OH BnO-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0680 PDP-C1-Ph-Val-Cit PDP-C1-Ph-Val-Cit is a cleavable ADC linker that can be used for antibody-drug conjugates (ADCs).
S0681 Amino-PEG6-alcohol Amino-PEG6-OH is a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0683 Aminoethyl-SS-ethylalcohol Aminoethyl-SS-ethylalcohol is an Alkyl-Chain-based PROTAC linker can be applied into the synthesis of PROTACs. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0684 Propargyl-PEG4-Tos Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0685 Propargyl-PEG2-acid Propargyl-PEG2-acid is a non-cleavable 2-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0686 NH2-PEG4-CH2CH2COOH NH2-PEG4-CH2CH2COOH is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0687 NH2-PEG6-Boc NH2-PEG6-Boc is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0688 m-PEG8-NHS ester m-PEG8-NHS ester is a non-cleavable 8-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0689 Bis-PEG8-acid Bis-PEG8-acid is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0691 N-Boc-PEG4-bromide N-Boc-PEG4-bromide is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0692 N3-Ph-NHS ester N3-Ph-NHS ester is a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0693 Bis-PEG3-NHS ester Bis-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used for antibody-drug-conjugation (ADC).
S0694 Bis-PEG5-NHS ester Bis-PEG5-NHS ester is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0695 5-Maleimidovaleric acid 5-Maleimidovaleric acid is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0696 Propargyl-PEG2-NHBoc Propargyl-PEG2-NHBoc is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be applied into the synthesis of PROTACs.
S0697 Mal-PEG2-NHS ester Mal-PEG2-NHS ester is a non-cleavable ADC linker consists of a Maleimide group, 2-unit PEG and an NHS ester.
S0698 Boc-NH-PEG4-CH2CH2COOH Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be applied into the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
S0700 GMBS GMBS is a cross-linker with heterobifunction.
S2982 DM1-SMCC DM1-SMCC (SMCC-DM1) 是一种 抗体药物偶联物 (ADC)-接头 (antibody drug conjugate (ADC)-linker),由有效的微管破坏剂 DM1 和接头 SMCC 组成。
S0627 PDEC-NB PDEC-NB 是一种二硫键可切割接头,可用于合成抗体药物偶联物 (ADC)。
S0671 Propargyl-PEG4-C2-acid Propargyl-PEG5-acid is a non-cleavable 5-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can to used to synthesize ADC inhibitors of Galectin-3.
S9795New Deruxtecan Deruxtecan是一种 ADC 药物-接头偶联物,由可切割的甘氨酸-甘氨酸-苯丙氨酸-甘氨酸四肽基接头、自我牺牲氨基亚甲基间隔物和新型拓扑异构酶 1 抑制剂有效载荷组成,它是 exatecan (DX-8951) 的衍生物。
Tags: ADC Linker inhibitor|ADC Linker agonist|ADC Linker activator|ADC Linker inducer|ADC Linker antagonist|ADC Linker signaling pathway|ADC Linker assay kit