BChE

抑制剂选择性比较

BChE产品

目录号 产品描述 文献引用 实验数据
S0924New

Pteryxin

Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物,也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂,IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生,其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。

S3245New

Nodakenetin

Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素,可抑制 α-glucosidasePTP1Brat lens aldose reductase (RLAR)AChEBChEβ-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 BaxBcl-2 的蛋白质表达,并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。

S5665

Drofenine Hydrochloride

Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.

S3835

Loganin

Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.

S5511

Ethyl (triphenylphosphoranylidene) acetate

Ethyl (triphenylphosphoranylidene) acetate may act as an inhibitor of cholinesterase that inhibits AChE and BChE.

目录号 产品描述 文献引用 实验数据
S0924New

Pteryxin

Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物,也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂,IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生,其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。

S3245New

Nodakenetin

Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素,可抑制 α-glucosidasePTP1Brat lens aldose reductase (RLAR)AChEBChEβ-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 BaxBcl-2 的蛋白质表达,并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。

S5665

Drofenine Hydrochloride

Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.

S3835

Loganin

Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.

S5511

Ethyl (triphenylphosphoranylidene) acetate

Ethyl (triphenylphosphoranylidene) acetate may act as an inhibitor of cholinesterase that inhibits AChE and BChE.