Dynamin
抑制剂选择性比较
Dynamin产品
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S8047 |
DynasoreDynasore是一种细胞渗透性的，可逆的，非竞争性dynamin抑制剂，抑制dynamin 1/2的GTPase活性，无细胞试验中IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。 |
Effects of dynasore on active caspase-3 expression at 3 days after SCI. c) Active caspase-3/NeuN/DAPI double labeling. Scale bars = 100 μm. |
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| S7162 |
Mdivi-1Mdivi-1是一个具有选择性和细胞穿膜性的线粒体分裂抑制剂，抑制了DRP1（发动蛋白相关GTP酶）和Dynamin I (Dnm1)的IC50为1-10 μM。 |
Cell necroptosis were detected in cells transfected with PCYT1A siRNA or treated with mitophagy inhibitor Mdivi-1 (50 μm).
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| S7163 |
Dyngo-4aDyngo-4a是一种有效的dynamin抑制剂，作用于DynI (brain)，DynI (rec)，和DynII (rec)，IC50分别为0.38 μM，1.1 μM，和 2.3 μM 。 |
Immunofluorescence analysis of EGFR distribution in HCC827 and H1650 cells treated with dynasore, dyngo-4a, or control reagents. Images were captured using a fluorescent microscope (Olympus BX63, 40X objective). Scale bar = 10 μm.
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| S5422New |
Trimethyloctadecylammonium bromideTrimethyloctadecylammonium bromide is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ. |
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S8047 |
DynasoreDynasore是一种细胞渗透性的，可逆的，非竞争性dynamin抑制剂，抑制dynamin 1/2的GTPase活性，无细胞试验中IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。 |
Effects of dynasore on active caspase-3 expression at 3 days after SCI. c) Active caspase-3/NeuN/DAPI double labeling. Scale bars = 100 μm. |
|
| S7162 |
Mdivi-1Mdivi-1是一个具有选择性和细胞穿膜性的线粒体分裂抑制剂，抑制了DRP1（发动蛋白相关GTP酶）和Dynamin I (Dnm1)的IC50为1-10 μM。 |
Cell necroptosis were detected in cells transfected with PCYT1A siRNA or treated with mitophagy inhibitor Mdivi-1 (50 μm).
|
|
| S7163 |
Dyngo-4aDyngo-4a是一种有效的dynamin抑制剂，作用于DynI (brain)，DynI (rec)，和DynII (rec)，IC50分别为0.38 μM，1.1 μM，和 2.3 μM 。 |
Immunofluorescence analysis of EGFR distribution in HCC827 and H1650 cells treated with dynasore, dyngo-4a, or control reagents. Images were captured using a fluorescent microscope (Olympus BX63, 40X objective). Scale bar = 10 μm.
|
|
| S5422New |
Trimethyloctadecylammonium bromideTrimethyloctadecylammonium bromide is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ. |
