HSV

HSV产品

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  • HSV抑制剂 (5)
目录号 产品名 产品描述 文献引用 实验数据
S4701 2-DG (2-Deoxy-D-glucose) 2-DG (2-Deoxy-D-glucose), 一种葡萄糖类似物,是具有抗病毒活性的糖酵解抑制剂。2-Deoxy-D-glucose 可诱导凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表达。
Int J Biol Sci, 2024, 20(3):848-863
Cell Stem Cell, 2023, 30(8):1028-1042.e7
Nat Cancer, 2023, 4(10):1508-1525
S8047 Dynasore Dynasore 是一种细胞渗透性的,可逆的,非竞争性dynamin抑制剂,抑制dynamin 1/2的GTPase活性,无细胞试验中IC50为15 μM,也抑制线粒体dynamin Drp1,对其他小GTP酶没有作用效果。Dynasore 可抑制 mTORC1 活性并诱导自噬。Dynasore 抑制多种病毒的入侵,包括HSV。
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
J Exp Med, 2023, 220(3)e20221316
S7546 Pritelivir (BAY 57-1293) Pritelivir (BAY 57-1293, AIC316)是一种强效的helicase primase抑制剂, 其对单纯性疱疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用,IC50为20 nM。
PLoS Pathog, 2021, 17(11):e1010117
J Virol, 2021, JVI0166621
S8428 FSL-1 FSL-1是一种细菌来源的toll样受体2/6 (toll-like receptor 2/6, TLR2/6)激动剂,可增强对实验性HSV-2感染的抵抗力。
S9070 Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S4701 2-DG (2-Deoxy-D-glucose) 2-DG (2-Deoxy-D-glucose), 一种葡萄糖类似物,是具有抗病毒活性的糖酵解抑制剂。2-Deoxy-D-glucose 可诱导凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表达。
Int J Biol Sci, 2024, 20(3):848-863
Cell Stem Cell, 2023, 30(8):1028-1042.e7
Nat Cancer, 2023, 4(10):1508-1525
S8047 Dynasore Dynasore 是一种细胞渗透性的,可逆的,非竞争性dynamin抑制剂,抑制dynamin 1/2的GTPase活性,无细胞试验中IC50为15 μM,也抑制线粒体dynamin Drp1,对其他小GTP酶没有作用效果。Dynasore 可抑制 mTORC1 活性并诱导自噬。Dynasore 抑制多种病毒的入侵,包括HSV。
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
J Exp Med, 2023, 220(3)e20221316
S7546 Pritelivir (BAY 57-1293) Pritelivir (BAY 57-1293, AIC316)是一种强效的helicase primase抑制剂, 其对单纯性疱疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用,IC50为20 nM。
PLoS Pathog, 2021, 17(11):e1010117
J Virol, 2021, JVI0166621
S8428 FSL-1 FSL-1是一种细菌来源的toll样受体2/6 (toll-like receptor 2/6, TLR2/6)激动剂,可增强对实验性HSV-2感染的抵抗力。
S9070 Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).

HSV抑制剂选择性比较

Tags: HSV inhibitor|HSV agonist|HSV activator|HSV inducer|HSV antagonist|HSV signaling pathway|HSV assay kit
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