Parasite
抑制剂选择性比较
Parasite产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S2468 |
FenbendazoleFenbendazole 是一种广谱苯并咪唑类驱虫药,作用于胃肠道寄生虫,IC50为0.01 μg/ml。 |
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S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680)是一种驱虫剂,作用于MDAY-D2 细胞,IC50为3 nM。 |
![]() ![]() Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
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S7379 |
E-64E-64是一种非可逆的、选择性的半胱氨酸蛋白酶抑制剂,同样也抑制木瓜蛋白酶、钙蛋白酶和cathepsins B、H,但不抑制丝氨酸蛋白酶或天冬氨酸蛋白酶。抑制木瓜蛋白酶的IC50为9nM。E-64 可在丝虫的寄生虫中诱导氧化应激和凋亡。 |
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S4044 |
ToltrazurilToltrazuril 是一种抗原生动物药剂,对球虫寄生虫有活性。 |
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S3741 |
BenznidazoleBenznidazole (Radanil)是一种硝基咪唑衍生物,能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用,因而具有抗原虫活性。 |
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S0081New |
DDD107498 succinateDDD107498 succinate (M-5717, DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2. |
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S4422 |
NitenpyramNitenpyram是一个nicotinic acetylcholine receptor (AchR)激动剂,用于兽医对家畜和宠物寄生虫的治疗。 |
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S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
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S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
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S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂,对几种寄生虫高度特异,不含任何有毒金属元素。 |
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S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S2468 |
FenbendazoleFenbendazole 是一种广谱苯并咪唑类驱虫药,作用于胃肠道寄生虫,IC50为0.01 μg/ml。 |
||
S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680)是一种驱虫剂,作用于MDAY-D2 细胞,IC50为3 nM。 |
![]() ![]() Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
|
|
S7379 |
E-64E-64是一种非可逆的、选择性的半胱氨酸蛋白酶抑制剂,同样也抑制木瓜蛋白酶、钙蛋白酶和cathepsins B、H,但不抑制丝氨酸蛋白酶或天冬氨酸蛋白酶。抑制木瓜蛋白酶的IC50为9nM。E-64 可在丝虫的寄生虫中诱导氧化应激和凋亡。 |
||
S4044 |
ToltrazurilToltrazuril 是一种抗原生动物药剂,对球虫寄生虫有活性。 |
||
S3741 |
BenznidazoleBenznidazole (Radanil)是一种硝基咪唑衍生物,能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用,因而具有抗原虫活性。 |
||
S0081New |
DDD107498 succinateDDD107498 succinate (M-5717, DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2. |
||
S4422 |
NitenpyramNitenpyram是一个nicotinic acetylcholine receptor (AchR)激动剂,用于兽医对家畜和宠物寄生虫的治疗。 |
||
S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
||
S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
||
S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂,对几种寄生虫高度特异,不含任何有毒金属元素。 |
||
S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |