Parasite
抑制剂选择性比较
Parasite产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S2468 |
FenbendazoleFenbendazole 是一种广谱苯并咪唑类驱虫药,作用于胃肠道寄生虫,IC50为0.01 μg/ml。 |
||
S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680)是一种驱虫剂,作用于MDAY-D2 细胞,IC50为3 nM。 |
![]() ![]() Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
|
|
S7379 |
E-64E-64是一种非可逆的、选择性的半胱氨酸蛋白酶抑制剂,同样也抑制木瓜蛋白酶、钙蛋白酶和cathepsins B、H,但不抑制丝氨酸蛋白酶或天冬氨酸蛋白酶。抑制木瓜蛋白酶的IC50为9nM。E-64 可在丝虫的寄生虫中诱导氧化应激和凋亡。 |
||
S3079 |
AtovaquoneAtovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。 |
||
S2028 |
DiclazurilDiclazuril 是一种抗球虫药。 |
||
S1851 |
OxibendazoleOxibendazole是一种广谱驱虫药。 |
||
S2501 |
Pyrantel PamoatePyrantel pamoate (Pyrantel Embonate)是一种广谱驱虫剂,用于治疗一些寄生虫感染。 |
||
S1691 |
PraziquantelPraziquantel是一种驱虫药,有效作用于扁形虫。 |
![]() ![]() Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development. |
|
S4141 |
DinitolmideDinitolmide (Zoalene) 是一种广谱抗球虫的药物。 |
||
S4044 |
ToltrazurilToltrazuril 是一种抗原生动物药剂,对球虫寄生虫有活性。 |
||
S4094 |
Tetramisole HClTetramisole是右旋和左旋异构体的混合物,用作驱虫剂。 |
||
S1830 |
OxfendazoleOxfendazole (RS-8858)是Fenbendazole的亚砜形式,是一种广谱的苯并咪唑类驱虫药。 |
||
S3999 |
α-santoninα-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent. |
||
S3741 |
BenznidazoleBenznidazole (Radanil)是一种硝基咪唑衍生物,能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用,因而具有抗原虫活性。 |
||
S4866 |
NicarbazinNicarbazin是一种有效的抗球虫试剂,是一种广谱的寄生虫药物。 |
||
S4876 |
Robenidine HydrochlorideRobenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) 是一种应用于家禽中的抗球虫剂。 |
||
S4145 |
DecoquinateDecoquinate是一种球虫抑制药。 |
||
S4599 |
Benzyl benzoateBenzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) 是治疗疥疮的旧制剂之一。 |
||
S4422 |
NitenpyramNitenpyram是一个nicotinic acetylcholine receptor (AchR)激动剂,用于兽医对家畜和宠物寄生虫的治疗。 |
||
S0081 |
DDD107498DDD107498 (M-5717, DDD-498) 是一种 P. falciparum translation elongation factor 2 的抑制剂。DDD107498 具有针对疟原虫寄生虫的多个生命周期阶段的有效地抗疟疾的活性。 |
||
S4610 |
MebendazoleMebendazole (Vermox, Telmin, Pantelmin, Mebenvet) 是一种合成的苯并咪唑衍生物,还是一种驱虫药物。它能通过抑制寄生虫的胞质微管的形成,干扰它们的生殖和生存,有选择性的、不可逆的抑制糖吸收。 |
||
S4167 |
CyromazineCyromazine是一种三嗪类昆虫生长调节剂,作为杀虫剂和杀螨剂。 |
||
S5722 |
Oxantel PamoateOxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting. |
||
S5345 |
NerolidolNerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties. |
||
S4898 |
Sulfalozine sodiumSulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) 是一种抗原生动物药,用于球虫病的研究。 |
||
S4068 |
TinidazoleTinidazole (CP12574)是抗寄生药。 |
||
S5816 |
PyrviniumPyrvinium是一种驱虫剂,对蛲虫有效。 |
||
S4882 |
ResorantelResorantel是一种安全的抗绦虫药,对莫尼茨绦虫和Thysaniezia spp.十分有效,对Paramphistomum spp.有一定效力。 |
||
S5017 |
OxyclozanideOxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox)是N-水杨酰苯胺驱虫剂,也是线粒体解偶联驱虫剂。兽用。 |
||
S5948 |
AmodiaquineAmodiaquine是一种合成的氨基喹啉,通过与原生动物或寄生DNA结合、阻止DNA和RNA的生成以及后续蛋白质的合成。它被用于治疗疟疾。 |
||
S3713 |
MoxidectinMoxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari. |
||
S3707 |
EthopabateEthopabate (ETP, Ethyl pabate)是一种球虫抑制剂,常被用于治疗鸡类球虫病。 |
||
S4104 |
Diminazene AceturateDiminazene是一种二脒,也称4,4-(1-三氮烯-1,3-二取代基)双(苯甲脒),用作有效的杀锥虫剂。 |
||
S5055 |
Milbemycin OximeMilbemycin Oxime是广谱性抗寄生虫药物,对蠕虫和螨虫具有活性作用。 |
||
S5031 |
Sulfaquinoxaline sodiumSulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na)是sulfaquinoxaline的钠盐形式,通过抑制微生物的核酸、蛋白的合成,用于治疗家禽、猪、羊的球虫病。 |
||
S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
||
S3591 |
EprinomectinEprinomectin (EPM, MK-397) 是一种极好的具有抗蠕虫、杀虫和杀螨活性的广谱杀菌剂。 |
||
S5094 |
Maduramycin AmmoniumMaduramicin,可分离来源于放射菌类Actinomadura rubra,是一种抗原虫剂,用于阻止球虫病,兽用。 |
||
S5093 |
RafoxanideRafoxanide (Disalan, Ranide, Flukanide, Bovanide)是一类N-水杨酰苯胺,被用作驱虫剂,在治疗和控制动物体内吸虫感染中有效。 |
||
S5092 |
FebantelFebantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) 是一种前体药物,可代谢成为fenbendazole和oxfendazole,它们是活性驱虫剂。 |
||
S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
||
S0467 |
EmodepsideEmodepside (QHT06, BAY 44-4400, PF 1022-221) 是一种PF1022A的半合成衍生物,是一种具有广谱的驱虫活性的环八肽。 Emodepside 可激活 Ca-dependent SLO-1-like K channels。 |
||
S4389 |
Bephenium HydroxynaphthoateBephenium 是一种 B-type Acetylcholine receptor (AChR) 的激活剂。Bephenium 可选择性地激活由Hco-UNC-29.1,Hco-UNC-38,Hco-UNC-63,Hco-ACR-8亚基组成的Hco-L-AChR1亚型。Bephenium hydroxynaphthoate 是一种驱虫药,以前用于治疗钩虫感染和蛔虫病。 |
||
S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂,对几种寄生虫高度特异,不含任何有毒金属元素。 |
||
S4999 |
Avermectin B1Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. |
||
S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S2468 |
FenbendazoleFenbendazole 是一种广谱苯并咪唑类驱虫药,作用于胃肠道寄生虫,IC50为0.01 μg/ml。 |
||
S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680)是一种驱虫剂,作用于MDAY-D2 细胞,IC50为3 nM。 |
![]() ![]() Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
|
|
S7379 |
E-64E-64是一种非可逆的、选择性的半胱氨酸蛋白酶抑制剂,同样也抑制木瓜蛋白酶、钙蛋白酶和cathepsins B、H,但不抑制丝氨酸蛋白酶或天冬氨酸蛋白酶。抑制木瓜蛋白酶的IC50为9nM。E-64 可在丝虫的寄生虫中诱导氧化应激和凋亡。 |
||
S3079 |
AtovaquoneAtovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。 |
||
S2028 |
DiclazurilDiclazuril 是一种抗球虫药。 |
||
S1851 |
OxibendazoleOxibendazole是一种广谱驱虫药。 |
||
S2501 |
Pyrantel PamoatePyrantel pamoate (Pyrantel Embonate)是一种广谱驱虫剂,用于治疗一些寄生虫感染。 |
||
S1691 |
PraziquantelPraziquantel是一种驱虫药,有效作用于扁形虫。 |
![]() ![]() Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development. |
|
S4141 |
DinitolmideDinitolmide (Zoalene) 是一种广谱抗球虫的药物。 |
||
S4044 |
ToltrazurilToltrazuril 是一种抗原生动物药剂,对球虫寄生虫有活性。 |
||
S4094 |
Tetramisole HClTetramisole是右旋和左旋异构体的混合物,用作驱虫剂。 |
||
S1830 |
OxfendazoleOxfendazole (RS-8858)是Fenbendazole的亚砜形式,是一种广谱的苯并咪唑类驱虫药。 |
||
S3999 |
α-santoninα-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent. |
||
S3741 |
BenznidazoleBenznidazole (Radanil)是一种硝基咪唑衍生物,能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用,因而具有抗原虫活性。 |
||
S4866 |
NicarbazinNicarbazin是一种有效的抗球虫试剂,是一种广谱的寄生虫药物。 |
||
S4876 |
Robenidine HydrochlorideRobenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) 是一种应用于家禽中的抗球虫剂。 |
||
S4145 |
DecoquinateDecoquinate是一种球虫抑制药。 |
||
S4599 |
Benzyl benzoateBenzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) 是治疗疥疮的旧制剂之一。 |
||
S4422 |
NitenpyramNitenpyram是一个nicotinic acetylcholine receptor (AchR)激动剂,用于兽医对家畜和宠物寄生虫的治疗。 |
||
S0081 |
DDD107498DDD107498 (M-5717, DDD-498) 是一种 P. falciparum translation elongation factor 2 的抑制剂。DDD107498 具有针对疟原虫寄生虫的多个生命周期阶段的有效地抗疟疾的活性。 |
||
S4610 |
MebendazoleMebendazole (Vermox, Telmin, Pantelmin, Mebenvet) 是一种合成的苯并咪唑衍生物,还是一种驱虫药物。它能通过抑制寄生虫的胞质微管的形成,干扰它们的生殖和生存,有选择性的、不可逆的抑制糖吸收。 |
||
S4167 |
CyromazineCyromazine是一种三嗪类昆虫生长调节剂,作为杀虫剂和杀螨剂。 |
||
S5722 |
Oxantel PamoateOxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting. |
||
S5345 |
NerolidolNerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties. |
||
S4898 |
Sulfalozine sodiumSulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) 是一种抗原生动物药,用于球虫病的研究。 |
||
S4068 |
TinidazoleTinidazole (CP12574)是抗寄生药。 |
||
S5816 |
PyrviniumPyrvinium是一种驱虫剂,对蛲虫有效。 |
||
S4882 |
ResorantelResorantel是一种安全的抗绦虫药,对莫尼茨绦虫和Thysaniezia spp.十分有效,对Paramphistomum spp.有一定效力。 |
||
S5017 |
OxyclozanideOxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox)是N-水杨酰苯胺驱虫剂,也是线粒体解偶联驱虫剂。兽用。 |
||
S5948 |
AmodiaquineAmodiaquine是一种合成的氨基喹啉,通过与原生动物或寄生DNA结合、阻止DNA和RNA的生成以及后续蛋白质的合成。它被用于治疗疟疾。 |
||
S3713 |
MoxidectinMoxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari. |
||
S3707 |
EthopabateEthopabate (ETP, Ethyl pabate)是一种球虫抑制剂,常被用于治疗鸡类球虫病。 |
||
S4104 |
Diminazene AceturateDiminazene是一种二脒,也称4,4-(1-三氮烯-1,3-二取代基)双(苯甲脒),用作有效的杀锥虫剂。 |
||
S5055 |
Milbemycin OximeMilbemycin Oxime是广谱性抗寄生虫药物,对蠕虫和螨虫具有活性作用。 |
||
S5031 |
Sulfaquinoxaline sodiumSulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na)是sulfaquinoxaline的钠盐形式,通过抑制微生物的核酸、蛋白的合成,用于治疗家禽、猪、羊的球虫病。 |
||
S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
||
S3591 |
EprinomectinEprinomectin (EPM, MK-397) 是一种极好的具有抗蠕虫、杀虫和杀螨活性的广谱杀菌剂。 |
||
S5094 |
Maduramycin AmmoniumMaduramicin,可分离来源于放射菌类Actinomadura rubra,是一种抗原虫剂,用于阻止球虫病,兽用。 |
||
S5093 |
RafoxanideRafoxanide (Disalan, Ranide, Flukanide, Bovanide)是一类N-水杨酰苯胺,被用作驱虫剂,在治疗和控制动物体内吸虫感染中有效。 |
||
S5092 |
FebantelFebantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) 是一种前体药物,可代谢成为fenbendazole和oxfendazole,它们是活性驱虫剂。 |
||
S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
||
S0467 |
EmodepsideEmodepside (QHT06, BAY 44-4400, PF 1022-221) 是一种PF1022A的半合成衍生物,是一种具有广谱的驱虫活性的环八肽。 Emodepside 可激活 Ca-dependent SLO-1-like K channels。 |
||
S4389 |
Bephenium HydroxynaphthoateBephenium 是一种 B-type Acetylcholine receptor (AChR) 的激活剂。Bephenium 可选择性地激活由Hco-UNC-29.1,Hco-UNC-38,Hco-UNC-63,Hco-ACR-8亚基组成的Hco-L-AChR1亚型。Bephenium hydroxynaphthoate 是一种驱虫药,以前用于治疗钩虫感染和蛔虫病。 |
||
S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂,对几种寄生虫高度特异,不含任何有毒金属元素。 |
||
S4999 |
Avermectin B1Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. |
||
S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |