RNR

抑制剂选择性比较

RNR产品

目录号 产品描述 文献引用 实验数据
S1218

Clofarabine

Clofarabine 抑制 ribonucleotide reductase (RNR) (IC50 = 65 nM)和 DNA polymerase 的酶活性。Clofarabine 可诱导自噬和凋亡。

S7470

Triapine

Triapine (3-AP) 是一种强效的ribonucleotide reductase (RNR)抑制剂,通过抑制DNA的合成而具有广谱抗肿瘤活性。

S0283New

COH-29

COH29 is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50 of 16 μM.

S3641

Osalmid

Osalmid suppresses ribonucleotide reductase (RR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.

目录号 产品描述 文献引用 实验数据
S1218

Clofarabine

Clofarabine 抑制 ribonucleotide reductase (RNR) (IC50 = 65 nM)和 DNA polymerase 的酶活性。Clofarabine 可诱导自噬和凋亡。

S7470

Triapine

Triapine (3-AP) 是一种强效的ribonucleotide reductase (RNR)抑制剂,通过抑制DNA的合成而具有广谱抗肿瘤活性。

S0283New

COH-29

COH29 is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50 of 16 μM.

S3641

Osalmid

Osalmid suppresses ribonucleotide reductase (RR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.