Substance P

抑制剂选择性比较

Substance P产品

新Substance P产品
产品目录 产品描述 文献引用 实验数据
S1189

Aprepitant

Aprepitant是一种有效的选择性neurokinin-1 receptor拮抗剂,IC50为0.1 nM。

S5476New

Rolapitant

Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.

S4654

Netupitant

Netupitant是一种选择性的神经激肽1(NK1)受体拮抗剂,具有潜在的止吐剂活性。

产品目录 产品描述 文献引用 实验数据
S1189

Aprepitant

Aprepitant是一种有效的选择性neurokinin-1 receptor拮抗剂,IC50为0.1 nM。

S5476New

Rolapitant

Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.

S4654

Netupitant

Netupitant是一种选择性的神经激肽1(NK1)受体拮抗剂,具有潜在的止吐剂活性。