Aldose Reductase

抑制剂选择性比较

Aldose Reductase产品

所有产品 Aldose Reductase抑制剂(6)

目录号	产品描述	文献引用	实验数据
S2035	Epalrestat Epalrestat (ONO-2235) 是一种醛糖还原酶 aldose reductase抑制剂，IC50为72 nM。	Int J Med Sci, 2020, 17(9):1246-1256 Mol Biol Rep, 2020, 10.1007/s11033-020-05685-z
S9196	Calceolarioside B Calceolarioside B, found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S3245^New	Nodakenetin Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素，可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 Bax 和 Bcl-2 的蛋白质表达，并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。
S5803	Alrestatin Alrestatin是aldose reductase (醛糖还原酶)抑制剂。醛糖还原酶参与了糖尿病并发症，包括糖尿病神经病变的发病机理。
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S2404	Isoliquiritigenin Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮，能抑制醛糖还原酶，IC50为320 nM。具有抗肿瘤活性。	Transl Vis Sci Technol, 2020, 9(9):39 Biomed Res Int, 2020, 2020:9259852 Int J Biol Sci, 2019, 15(11):2497-2508	Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.

目录号	产品描述	文献引用	实验数据
S2035	Epalrestat Epalrestat (ONO-2235) 是一种醛糖还原酶 aldose reductase抑制剂，IC50为72 nM。	Int J Med Sci,2020, 17(9):1246-1256 Mol Biol Rep,2020, 10.1007/s11033-020-05685-z
S9196	Calceolarioside B Calceolarioside B, found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S3245^New	Nodakenetin Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素，可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 Bax 和 Bcl-2 的蛋白质表达，并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。
S5803	Alrestatin Alrestatin是aldose reductase (醛糖还原酶)抑制剂。醛糖还原酶参与了糖尿病并发症，包括糖尿病神经病变的发病机理。
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S2404	Isoliquiritigenin Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮，能抑制醛糖还原酶，IC50为320 nM。具有抗肿瘤活性。	Transl Vis Sci Technol,2020, 9(9):39 Biomed Res Int,2020, 2020:9259852 Int J Biol Sci,2019, 15(11):2497-2508	Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.