Aldose Reductase
抑制剂选择性比较
Aldose Reductase产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
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S2035 |
EpalrestatEpalrestat (ONO-2235) 是一种醛糖还原酶 aldose reductase抑制剂,IC50为72 nM。 |
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S9196 |
Calceolarioside BCalceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property. |
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S3245New |
NodakenetinNodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素,可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 Bax 和 Bcl-2 的蛋白质表达,并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。 |
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S5803 |
AlrestatinAlrestatin是aldose reductase (醛糖还原酶)抑制剂。醛糖还原酶参与了糖尿病并发症,包括糖尿病神经病变的发病机理。 |
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S5446 |
2-Chloro-1-(4-fluorobenzyl)benzimidazole2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative. |
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S2404 |
IsoliquiritigeninIsoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮,能抑制醛糖还原酶,IC50为320 nM。具有抗肿瘤活性。 |
![]() ![]() Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.
|
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S2035 |
EpalrestatEpalrestat (ONO-2235) 是一种醛糖还原酶 aldose reductase抑制剂,IC50为72 nM。 |
||
S9196 |
Calceolarioside BCalceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property. |
||
S3245New |
NodakenetinNodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素,可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 Bax 和 Bcl-2 的蛋白质表达,并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。 |
||
S5803 |
AlrestatinAlrestatin是aldose reductase (醛糖还原酶)抑制剂。醛糖还原酶参与了糖尿病并发症,包括糖尿病神经病变的发病机理。 |
||
S5446 |
2-Chloro-1-(4-fluorobenzyl)benzimidazole2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative. |
||
S2404 |
IsoliquiritigeninIsoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮,能抑制醛糖还原酶,IC50为320 nM。具有抗肿瘤活性。 |
![]() ![]() Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.
|