SUMO
抑制剂选择性比较
SUMO产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S4922New |
NSC 632839NSC 632839不仅是一种DUB抑制剂,也是一种deSUMOylase抑制剂,作用于USP2, USP7,和SENP2, EC50分别为45 μM, 37 μM和9.8 μM。 |
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S8829New |
TAK-981TAK-981 是一种新型的 SUMOylation enzymatic cascade 的选择性抑制剂,具有潜在的免疫激活和抗肿瘤活性。 |
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S8696 |
2-D082-D08 (2',3',4'-trihydroxy flavone) 是一种具有细胞透性的蛋白类泛素化(protein sumoylation)抑制剂。它还能抑制Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR和PI3Kα,IC50分别为0.49, 3.9, 5.3, 9.8, 11, 11, 17和35 nM。 |
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S9432 |
Ginkgolic AcidGinkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT). |
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S9445 |
Ginkgolic Acid (C13:0)Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂,对变形链球菌(S. mutans)具有抗菌活性,并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂,据报道可抑制 histone acetylation transferase (HAT) 。 |
||
S9159 |
momordin-IcMomordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo. |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S4922New |
NSC 632839NSC 632839不仅是一种DUB抑制剂,也是一种deSUMOylase抑制剂,作用于USP2, USP7,和SENP2, EC50分别为45 μM, 37 μM和9.8 μM。 |
||
S8829New |
TAK-981TAK-981 是一种新型的 SUMOylation enzymatic cascade 的选择性抑制剂,具有潜在的免疫激活和抗肿瘤活性。 |
||
S8696 |
2-D082-D08 (2',3',4'-trihydroxy flavone) 是一种具有细胞透性的蛋白类泛素化(protein sumoylation)抑制剂。它还能抑制Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR和PI3Kα,IC50分别为0.49, 3.9, 5.3, 9.8, 11, 11, 17和35 nM。 |
||
S9432 |
Ginkgolic AcidGinkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT). |
||
S9445 |
Ginkgolic Acid (C13:0)Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂,对变形链球菌(S. mutans)具有抗菌活性,并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂,据报道可抑制 histone acetylation transferase (HAT) 。 |
||
S9159 |
momordin-IcMomordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo. |