VMAT
抑制剂选择性比较
VMAT产品
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S1601 |
ReserpineReserpine是一种吲哚类生物碱抗精神病药和抗高血压药物，已被用于控制高血压，及缓解精神病症状。 |
(A) Changes of cAMP levels measured by the cAMP-Glo assay (Promega). Gpr52 siRNAs were tranfected for 3 days, whereas the compound treatment (forskolin: 1 μM; reserpine: 10 μM) lasts for 24 hr; statistical analyses performed by the twotailed Mann-Whitney U test. (B) Htt level measured by the 2B7/2166 HTRF upon treatment of different doses of the Gpr52 agonist reserpine for 48 hr, with transfection of Gpr52 siRNA (Gpr52_si1) vs the non-targeting control (Neg_si), n = 4. |
|
| S9500 |
Valbenazine tosylateValbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM）. |
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S1601 |
ReserpineReserpine是一种吲哚类生物碱抗精神病药和抗高血压药物，已被用于控制高血压，及缓解精神病症状。 |
(A) Changes of cAMP levels measured by the cAMP-Glo assay (Promega). Gpr52 siRNAs were tranfected for 3 days, whereas the compound treatment (forskolin: 1 μM; reserpine: 10 μM) lasts for 24 hr; statistical analyses performed by the twotailed Mann-Whitney U test. (B) Htt level measured by the 2B7/2166 HTRF upon treatment of different doses of the Gpr52 agonist reserpine for 48 hr, with transfection of Gpr52 siRNA (Gpr52_si1) vs the non-targeting control (Neg_si), n = 4. |
|
| S9500 |
Valbenazine tosylateValbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM）. |
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