cGAS

cGAS产品

目录号	产品描述	文献引用	实验数据
S6841New	RU.521 RU.521 是一种活跃的 cyclic GMP-AMP synthase (cGAS) 的有效的选择性抑制剂，可抑制cGAS介导的信号传导，其IC50值为700 nM。RU.521 与cGAS/dsDNA 复合物结合的Kd值为36.2 nM。
S9615New	PF-06928215 PF-06928215 is a high affinity active site-targeting, substrate-competitive cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 4.9 μM.
S0775New	IRAK4-IN-4 IRAK4-IN-4 is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) with IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with IC50 of 2.1 nM.
S8944New	G150 G150是一种有效的、高选择性的 human cyclic GMP-AMP synthase (cGAS) 抑制剂，IC50为10.2 nM。

目录号	产品描述	文献引用	实验数据
S6841New	RU.521 RU.521 是一种活跃的 cyclic GMP-AMP synthase (cGAS) 的有效的选择性抑制剂，可抑制cGAS介导的信号传导，其IC50值为700 nM。RU.521 与cGAS/dsDNA 复合物结合的Kd值为36.2 nM。
S9615New	PF-06928215 PF-06928215 is a high affinity active site-targeting, substrate-competitive cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 4.9 μM.
S0775New	IRAK4-IN-4 IRAK4-IN-4 is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) with IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with IC50 of 2.1 nM.
S8944New	G150 G150是一种有效的、高选择性的 human cyclic GMP-AMP synthase (cGAS) 抑制剂，IC50为10.2 nM。