ASK1 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S0067 GS-444217 GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM. Selective ASK1, IC50: 2.87 nM
S8292 Selonsertib (GS-4997) Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selective ASK1, pIC50: 8.3
S8289 NQDI-1 NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death. Selective ASK1, IC50: 3 μM
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