CD88 选择性拮抗剂
| 目录号 |
产品名 |
产品描述 |
Selective / Pan |
IC50 / Ki |
| S0474 |
Avacopan |
Avacopan is an orally administered and selective C5a receptor (C5aR) antagonist. |
Selective |
|
| S6239 |
PMX-53 |
PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2). |
Selective |
|
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