• FLT3-WT
  • FLT3-ITD
  • FLT3-D835Y

FLT3-WT 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S9892 HM43239

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.

Pan FLT3-WT, IC50: 1.1 nM
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