• KLF4
  • KLF5

KLF4 选择性激活剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6963 APTO-253

APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4).

Selective
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