Kinesin-12 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6953 GW406108X GW406108X (GW108X) is an inhibitor of Kif15 (Kinesin-12) with an IC50 of 0.82 μM in the ATPase assay. GW406108X inhibits recombinant ULK1 kinase activity with a pIC50 of 6.37 and blocks autophagy in cells, without affecting the upstream signalling kinases mTORC1 and AMPK. Selective Kif15, IC50: 0.82 μM
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