MAP4K7 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S8392 NCB-0846

NCB-0846是一种新型的、口服的Wnt小分子化合物抑制剂,抑制TNIK (TRAF2 and NCK-Interacting Kinase)的IC50为21 nM。

Selective TNIK, IC50: 21 nM
S0268 DMX-5084

DMX-5804 is a potent, orally active and selective inhibitor of MAP4K4 with IC50 of 3 nM. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.

Pan TNIK/MAP4K7, pIC50: 7.96