• MAP4K2
  • MAP4K4
  • MAP4K6
  • MAP4K7

MAP4K7 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S8392 NCB-0846 NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase, MAP4K7) with an IC50 value of 21 nM. Selective TNIK, IC50: 21 nM
S0268 DMX-5084 DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. Pan TNIK/MAP4K7, pIC50: 7.96
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