PI4KIIIbeta 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S0041 UCB9608

UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor with IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. UCB9608 is a potent immunosuppressive agent that improves metabolic stability and exhibits excellent pharmacokinetic profile.

Selective PI4KIIIβ, IC50: 11 nM
S1489 PIK-93

PIK-93是第一个有效的,人工合成的PI4K(PI4KIIIβ)抑制剂,IC50为19 nM;抑制PI3KαIC50为39 nM。

Selective PI4KIIIβ, IC50: 19 nM
S6571 BQR695

BQR695 (NVP-BQR695) is a quinoxaline that displays sub-micromolar potency against human PI4KIIIβ (IC50~90 nM).

Selective PI4KIIIβ, IC50: ~90 nM