RORalpha 选择性激动剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S2654 Neoruscogenin

Neoruscogenin, a natural sapogenin isolated from R. rhizoma, is a potent and high-affinity agonist of RAR-related orphan receptor alpha (RORα or nuclear receptor NR1F1).

Selective
S5775 SR1078

SR1078, a synthetic ligand for RORα and RORγ, functions as a RORα/γ agonist.

Pan
S6724 SR1001

SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively.

Pan RORα, Ki: 172 nM