Y2 选择性拮抗剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6416 JNJ 31020028

JNJ 31020028 is a novel neuropeptide Y Y2 receptor antagonist which bound with high affinity with human and rat Y2 receptor (pIC50=8.07±0.05 for human Y2 receptor, and pIC50=8.22±0.06 for rat Y2 receptor) and >100-fold selective versus human Y1, Y4, and Y5 receptors.

Selective rat Y2 receptor, pIC50: 8.22; human Y2 receptor, pIC50: 8.07