WDR5
抑制剂选择性比较
WDR5产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
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S7833 |
OICR-9429OICR-9429是一种有效的WDR5-MLL、WDR5-Histone3相互作用的拮抗剂,能在体外实验中降低急性髓性白血病细胞的活性。它与WDR5高亲和结合,Kd值为93 ± 28 nM。 |
![]() ![]() (F) Real-time PCR analysis showed the VEGFA mRNA expression in the HOXC10-overexpressing glioma cells treated with vehicle or 1 μM OICR-9429 for 2 days. (G) ChIP-qPCR enrichments of H3K4me3, polymerase II or IgG on VEGFA promoter region 3 in the HOXC10-overexpressing glioma cells treated with vehicle or 1 μM OICR-9429 for 2 days. All the assays shown in the figure were independently replicated three times. Error bars, SD. * P < 0.05.
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S2184 |
WDR5-0103WDR5-0103 (WD-Repeat Protein 5-0103)是一种WDR5 (WD40 repeat protein 5)的小分子拮抗剂,Kd值为450 nM。 |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S7833 |
OICR-9429OICR-9429是一种有效的WDR5-MLL、WDR5-Histone3相互作用的拮抗剂,能在体外实验中降低急性髓性白血病细胞的活性。它与WDR5高亲和结合,Kd值为93 ± 28 nM。 |
![]() ![]() (F) Real-time PCR analysis showed the VEGFA mRNA expression in the HOXC10-overexpressing glioma cells treated with vehicle or 1 μM OICR-9429 for 2 days. (G) ChIP-qPCR enrichments of H3K4me3, polymerase II or IgG on VEGFA promoter region 3 in the HOXC10-overexpressing glioma cells treated with vehicle or 1 μM OICR-9429 for 2 days. All the assays shown in the figure were independently replicated three times. Error bars, SD. * P < 0.05.
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S2184 |
WDR5-0103WDR5-0103 (WD-Repeat Protein 5-0103)是一种WDR5 (WD40 repeat protein 5)的小分子拮抗剂,Kd值为450 nM。 |