Fatty Acid Synthase
抑制剂选择性比较
Fatty Acid Synthase产品
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S2697 |
A-769662A-769662是一种有效的，可逆的AMPK激活剂，在无细胞试验中EC50为0.8 μM，对GPPase/FBPase活性几乎没有作用。 |
Cells were treated with CP, DOXO, SRT1720 (100 nM), EX527 (100 nM), A769662 (10 μM) and Compound C (1 μM) under normoxic or hypoxic conditions for 48 hours, and then their viabilities were measured by MTT. |
|
| S1629 |
OrlistatOrlistat是一种通用的脂肪酶抑制剂，作用于人体十二指肠液的PL，IC50为122 ng/ml。 |
||
| S1937 |
IsoniazidIsoniazid是一种前体药物，通过与KatG 相互作用阻断了脂肪酸合成酶的作用，用于结核的预防和治疗。 |
||
| S8284 |
Fatostatin HBrFatostatin是固醇调节元件结合蛋白(SREBP)的抑制剂。它损害SREBP-1和SREBP-2的激活。 |
||
| S6666New |
FT113FT113是一种fatty acid synthase (FAS/FASN)抑制剂，ic50为213 nM。 |
||
| S8915New |
C75C75 是一种 fatty acid synthase (FAS/FASN) 的新型有效的合成抑制剂，在成株试验和球体生长测定中的IC50值分别为35 μM和50 μM。C75 可用作研究代谢紊乱和癌症中脂肪酸合成的工具。 |
||
| S8563New |
TVB-3664TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor. |
||
| S2250 |
(-)-Epigallocatechin Gallate(-)-Epigallocatechin Gallate是从绿茶中分离的一种有效的抗氧化剂Polyphenol flavonoid。抑制telomerase和DNA methyltransferase， 阻滞EGF受体和HER-2受体的激活，抑制脂肪酸合成酶以及谷氨酸脱氢酶的活性。 |
|
|
| S4754 |
BetulinBetulin (BE), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity. |
||
| S8588 |
ACSS2 inhibitorACSS2 inhibitor是有效的、特异性的乙酰辅酶A合成酶2 (ACSS2)抑制剂。 |
||
| S2314 |
KaempferolKaempferol是一种黄酮，是ERRα和ERRγ的反向激动剂。抑制topoisomerase I催化的DNA再连接和fatty acid synthase的活性。 |
Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).
|
|
| S9392 |
Praeruptorin BPraeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities. |
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S2697 |
A-769662A-769662是一种有效的，可逆的AMPK激活剂，在无细胞试验中EC50为0.8 μM，对GPPase/FBPase活性几乎没有作用。 |
Cells were treated with CP, DOXO, SRT1720 (100 nM), EX527 (100 nM), A769662 (10 μM) and Compound C (1 μM) under normoxic or hypoxic conditions for 48 hours, and then their viabilities were measured by MTT. |
|
| S1629 |
OrlistatOrlistat是一种通用的脂肪酶抑制剂，作用于人体十二指肠液的PL，IC50为122 ng/ml。 |
||
| S1937 |
IsoniazidIsoniazid是一种前体药物，通过与KatG 相互作用阻断了脂肪酸合成酶的作用，用于结核的预防和治疗。 |
||
| S8284 |
Fatostatin HBrFatostatin是固醇调节元件结合蛋白(SREBP)的抑制剂。它损害SREBP-1和SREBP-2的激活。 |
||
| S6666New |
FT113FT113是一种fatty acid synthase (FAS/FASN)抑制剂，ic50为213 nM。 |
||
| S8915New |
C75C75 是一种 fatty acid synthase (FAS/FASN) 的新型有效的合成抑制剂，在成株试验和球体生长测定中的IC50值分别为35 μM和50 μM。C75 可用作研究代谢紊乱和癌症中脂肪酸合成的工具。 |
||
| S8563New |
TVB-3664TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor. |
||
| S2250 |
(-)-Epigallocatechin Gallate(-)-Epigallocatechin Gallate是从绿茶中分离的一种有效的抗氧化剂Polyphenol flavonoid。抑制telomerase和DNA methyltransferase， 阻滞EGF受体和HER-2受体的激活，抑制脂肪酸合成酶以及谷氨酸脱氢酶的活性。 |
|
|
| S4754 |
BetulinBetulin (BE), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity. |
||
| S8588 |
ACSS2 inhibitorACSS2 inhibitor是有效的、特异性的乙酰辅酶A合成酶2 (ACSS2)抑制剂。 |
||
| S2314 |
KaempferolKaempferol是一种黄酮，是ERRα和ERRγ的反向激动剂。抑制topoisomerase I催化的DNA再连接和fatty acid synthase的活性。 |
Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).
|
|
| S9392 |
Praeruptorin BPraeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities. |
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