Tyrosinase

抑制剂选择性比较

Tyrosinase产品

所有产品 Tyrosinase抑制剂(11)

产品目录	产品描述	文献引用	实验数据
S4921	MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN) MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)是一种酪氨酸激酶抑制剂，抑制Syk， Src和p97， IC50分别为2.5 μM， 29.3 μM和1.7 μM。	J Biomol Struct Dyn, 2019, 10.1080/07391102.2019.1640133 Toxicol Res (Camb), 2016, 5(1):188-196	WT mouse primary macrophages were untreated as control (lane 1) or treated with 0.1μg/ml E. coli LPS (lane 5-8), 10μM E-64 (lane 2 and 6), 250μM PMSF (lane 3 and 7), or 20μM MNS (lane 4 and 8). The cells were continuously cultured for 16 hrs. Extracts from whole cells or nuclei were separately purified and subjected to WB analysis with antibody against pERK2, LITAF, or actin/tubulin as control.
S1652	Monobenzone Monobenzone是一种外用药，用于治疗皮肤色素脱失。它能特异性地抑制tyrosinase。
S4132	Deoxyarbutin DeoxyArbutin 是一种可逆的酪氨酸酶抑制剂,抑制酪氨酸酶活性，IC50为50 nM。
S4571	Hexylresorcinol Hexylresorcinol是一种具有局部麻醉效果、抗菌和驱虫剂特性的有机化合物。是酪氨酸酶的有效抑制剂。hexylresorcinol对单酚酶的IC50为1.24 μM，对二酚酶的IC50值为0.85 μM。
S2375	Aloin Aloin是有效的酪氨酸酶抑制剂，作用于HeLaS3细胞，IC50为97 μM。	Drug Des Devel Ther, 2019, 13:1221-1231
S2263	Arbutin Arbutin是一种酪氨酸酶抑制剂，IC50为1.09 mM。
S9284	Aloesin Aloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.
S4997	4-Butylresorcinol 4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent.
S9089	Magnoflorine Magnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.
S5174	Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
S9111	Isorhamnetin Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.

产品目录	产品描述	文献引用	实验数据
S4921	MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN) MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)是一种酪氨酸激酶抑制剂，抑制Syk， Src和p97， IC50分别为2.5 μM， 29.3 μM和1.7 μM。	J Biomol Struct Dyn,2019, 10.1080/07391102.2019.1640133 Toxicol Res (Camb),2016, 5(1):188-196	WT mouse primary macrophages were untreated as control (lane 1) or treated with 0.1μg/ml E. coli LPS (lane 5-8), 10μM E-64 (lane 2 and 6), 250μM PMSF (lane 3 and 7), or 20μM MNS (lane 4 and 8). The cells were continuously cultured for 16 hrs. Extracts from whole cells or nuclei were separately purified and subjected to WB analysis with antibody against pERK2, LITAF, or actin/tubulin as control.
S1652	Monobenzone Monobenzone是一种外用药，用于治疗皮肤色素脱失。它能特异性地抑制tyrosinase。
S4132	Deoxyarbutin DeoxyArbutin 是一种可逆的酪氨酸酶抑制剂,抑制酪氨酸酶活性，IC50为50 nM。
S4571	Hexylresorcinol Hexylresorcinol是一种具有局部麻醉效果、抗菌和驱虫剂特性的有机化合物。是酪氨酸酶的有效抑制剂。hexylresorcinol对单酚酶的IC50为1.24 μM，对二酚酶的IC50值为0.85 μM。
S2375	Aloin Aloin是有效的酪氨酸酶抑制剂，作用于HeLaS3细胞，IC50为97 μM。	Drug Des Devel Ther,2019, 13:1221-1231
S2263	Arbutin Arbutin是一种酪氨酸酶抑制剂，IC50为1.09 mM。
S9284	Aloesin Aloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.
S4997	4-Butylresorcinol 4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent.
S9089	Magnoflorine Magnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.
S5174	Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
S9111	Isorhamnetin Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.