Tyrosinase

  • 抑制剂选择性比较
  • 溶解性比较
目录号 产品目录 溶解度(25°C)
DMSO 酒精
S4921 MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN) <1 mg/mL 39 mg/mL <1 mg/mL
S1652 Monobenzone <1 mg/mL 40 mg/mL 40 mg/mL
S4132 Deoxyarbutin <1 mg/mL 39 mg/mL 39 mg/mL
S4571 Hexylresorcinol <1 mg/mL 38 mg/mL 38 mg/mL
S2375 Aloin 83 mg/mL 83 mg/mL 2 mg/mL
S4997 4-Butylresorcinol -1 mg/mL 34 mg/mL -1 mg/mL
S5174 Kojic acid -1 mg/mL 28 mg/mL -1 mg/mL
S2263 Arbutin 55 mg/mL 55 mg/mL <1 mg/mL
产品目录 产品描述 文献引用 实验数据
S4921

MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)

MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)是一种酪氨酸激酶抑制剂,抑制SykSrcp97IC50分别为2.5 μM, 29.3 μM和1.7 μM。

S1652

Monobenzone

Monobenzone是一种外用药,用于治疗皮肤色素脱失。它能特异性地抑制tyrosinase

S4132

Deoxyarbutin

DeoxyArbutin 是一种可逆的酪氨酸酶抑制剂,抑制酪氨酸酶活性,IC50为50 nM。

S4571

Hexylresorcinol

Hexylresorcinol是一种具有局部麻醉效果、抗菌和驱虫剂特性的有机化合物。是酪氨酸酶的有效抑制剂。hexylresorcinol对单酚酶的IC50为1.24 μM,对二酚酶的IC50值为0.85 μM。

S2375

Aloin

Aloin是有效的酪氨酸酶抑制剂,作用于HeLaS3细胞,IC50为97 μM。

S4997New

4-Butylresorcinol

4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent.

S9284New

Aloesin

Aloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.

S9089New

Magnoflorine

Magnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.

S9111New

Isorhamnetin

Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.

S5174New

Kojic acid

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

S2263

Arbutin

Arbutin是一种酪氨酸酶抑制剂,IC50为1.09 mM。