Tyrosinase
抑制剂选择性比较
Tyrosinase产品
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S4921 |
MNS (3,4-Methylenedioxy-β-nitrostyrene)MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)是一种酪氨酸激酶抑制剂，抑制Syk， Src和p97， IC50分别为2.5 μM， 29.3 μM和1.7 μM。 |
WT mouse primary macrophages were untreated as control (lane 1) or treated with 0.1μg/ml E. coli LPS (lane 5-8), 10μM E-64 (lane 2 and 6), 250μM PMSF (lane 3 and 7), or 20μM MNS (lane 4 and 8). The cells were continuously cultured for 16 hrs. Extracts from whole cells or nuclei were separately purified and subjected to WB analysis with antibody against pERK2, LITAF, or actin/tubulin as control.
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| S1652 |
MonobenzoneMonobenzone是一种外用药，用于治疗皮肤色素脱失。它能特异性地抑制tyrosinase。 |
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| S4132 |
DeoxyarbutinDeoxyArbutin 是一种可逆的酪氨酸酶抑制剂,抑制酪氨酸酶活性，IC50为50 nM。 |
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| S6237 |
2-Ketoglutaric acid2-Ketoglutaric acid是三羧酸循环中的关键分子，是该代谢过程的限速节点。在三羧酸循环中，2-Ketoglutaric acid脱羧基生成琥珀酰辅酶和二氧化碳。 |
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| S4571 |
HexylresorcinolHexylresorcinol是一种具有局部麻醉效果、抗菌和驱虫剂特性的有机化合物。是酪氨酸酶的有效抑制剂。hexylresorcinol对单酚酶的IC50为1.24 μM，对二酚酶的IC50值为0.85 μM。 |
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| S6272 |
Glycolic acidGlycolic acid (or hydroxyacetic acid)是一种果酸。由于它能很好地穿透皮肤，经常被用于护肤品中，用作美容换肤。 |
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| S2375 |
AloinAloin是有效的酪氨酸酶抑制剂，作用于HeLaS3细胞，IC50为97 μM。 |
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| S2263 |
ArbutinArbutin是一种酪氨酸酶抑制剂，IC50为1.09 mM。 |
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| S4739 |
OxyresveratrolOxyresveratrol是从Morus alba L.发现的天然化合物，对酪氨酸酶的多巴氧化酶活性具有有效抑制作用，能催化黑色素生物合成的限速步骤。 |
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| S9284 |
AloesinAloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro. |
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| S4997 |
4-Butylresorcinol4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. |
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| S3691 |
4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid4-Chlorosalicylic acid被用于混合稀土中对铽放入灵敏性荧光法测定以及利用甲醛缩合制备poly(4-chlorosalicylic acid-formaldehyde)中。 |
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| S9089 |
MagnoflorineMagnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase. |
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| S5174 |
Kojic acidKojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives. |
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| S9111 |
IsorhamnetinIsorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity. |
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| S9376 |
BenzylacetoneBenzylacetone is an attractant compound in flowers. |
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| S6221 |
Methyl cinnamateMethyl cinnamate 是花椒(Zanthoxylum armatum)的活性成分，是一种广泛使用的具有抗菌和 tyrosinase 抑制剂活性的天然香料化合物。Methyl cinnamate 通过激活3T3-L1前脂肪细胞中的 CaMKK2--AMPK 信号通路来抑制脂肪细胞分化。 |
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| S3783 |
EchinacosideEchinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions. |
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S4921 |
MNS (3,4-Methylenedioxy-β-nitrostyrene)MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)是一种酪氨酸激酶抑制剂，抑制Syk， Src和p97， IC50分别为2.5 μM， 29.3 μM和1.7 μM。 |
WT mouse primary macrophages were untreated as control (lane 1) or treated with 0.1μg/ml E. coli LPS (lane 5-8), 10μM E-64 (lane 2 and 6), 250μM PMSF (lane 3 and 7), or 20μM MNS (lane 4 and 8). The cells were continuously cultured for 16 hrs. Extracts from whole cells or nuclei were separately purified and subjected to WB analysis with antibody against pERK2, LITAF, or actin/tubulin as control.
|
|
| S1652 |
MonobenzoneMonobenzone是一种外用药，用于治疗皮肤色素脱失。它能特异性地抑制tyrosinase。 |
||
| S4132 |
DeoxyarbutinDeoxyArbutin 是一种可逆的酪氨酸酶抑制剂,抑制酪氨酸酶活性，IC50为50 nM。 |
||
| S6237 |
2-Ketoglutaric acid2-Ketoglutaric acid是三羧酸循环中的关键分子，是该代谢过程的限速节点。在三羧酸循环中，2-Ketoglutaric acid脱羧基生成琥珀酰辅酶和二氧化碳。 |
||
| S4571 |
HexylresorcinolHexylresorcinol是一种具有局部麻醉效果、抗菌和驱虫剂特性的有机化合物。是酪氨酸酶的有效抑制剂。hexylresorcinol对单酚酶的IC50为1.24 μM，对二酚酶的IC50值为0.85 μM。 |
||
| S6272 |
Glycolic acidGlycolic acid (or hydroxyacetic acid)是一种果酸。由于它能很好地穿透皮肤，经常被用于护肤品中，用作美容换肤。 |
||
| S2375 |
AloinAloin是有效的酪氨酸酶抑制剂，作用于HeLaS3细胞，IC50为97 μM。 |
||
| S2263 |
ArbutinArbutin是一种酪氨酸酶抑制剂，IC50为1.09 mM。 |
||
| S4739 |
OxyresveratrolOxyresveratrol是从Morus alba L.发现的天然化合物，对酪氨酸酶的多巴氧化酶活性具有有效抑制作用，能催化黑色素生物合成的限速步骤。 |
||
| S9284 |
AloesinAloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro. |
||
| S4997 |
4-Butylresorcinol4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. |
||
| S3691 |
4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid4-Chlorosalicylic acid被用于混合稀土中对铽放入灵敏性荧光法测定以及利用甲醛缩合制备poly(4-chlorosalicylic acid-formaldehyde)中。 |
||
| S9089 |
MagnoflorineMagnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase. |
||
| S5174 |
Kojic acidKojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives. |
||
| S9111 |
IsorhamnetinIsorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity. |
||
| S9376 |
BenzylacetoneBenzylacetone is an attractant compound in flowers. |
||
| S6221 |
Methyl cinnamateMethyl cinnamate 是花椒(Zanthoxylum armatum)的活性成分，是一种广泛使用的具有抗菌和 tyrosinase 抑制剂活性的天然香料化合物。Methyl cinnamate 通过激活3T3-L1前脂肪细胞中的 CaMKK2--AMPK 信号通路来抑制脂肪细胞分化。 |
| 目录号 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S3783 |
EchinacosideEchinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions. |
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