GLUT

特异性亚型抑制剂

• GLUT1 Selective

GLUT产品

目录号	产品描述	文献引用	实验数据
S7931	STF-31 STF-31是一种选择性葡萄糖转运蛋白GLUT1抑制剂。	Cell Metab, 2020, 31(3):564-579 Sci Adv, 2020, 6;6(19):eaay9466 Theranostics, 2020, 6;10(12):5259-5275	NP69 cells were transfected with LMP1 expression plasmid and treated with STF-31 or infected with lentivirus expressing shGlut-1 for 48 h. The cells were then lysed and subjected to Western blotting using specific antibodies against Glut-1 and cleaved caspase 3. β-Actin expression was used as the loading control.
S7927	WZB117 WZB117是GLUT1的抑制剂，它可以抑制肺癌细胞A549和乳腺癌MCF7细胞的细胞增殖，IC50约为10 μM。	Neurosci Bull, 2021, 10.1007/s12264-020-00624-1 J Cell Physiol, 2020, 10.1002 Nat Commun, 2019, 10(1):3981
S8452	BAY-876 BAY-876是有效的、选择性的GLUT1抑制剂（IC50=0.002 μM），对GLUT1的选择性比对GLUT2, GLUT3和GLUT4的选择性高100倍。	SSRN, 2021, 10.2139/ssrn.3862792 Biomaterials, 2020, 239:119839 Elife, 2020, 9e56749
S9636	DRB18 DRB18 是一种 pan-GLUT (glucose transporters) 的抑制剂，可高活性地抑制几种癌症类型的生长和增殖。
S5748	4′-Deoxyphlorizin 4'-Deoxyphlorizin is an inhibitor of the glucose transport system.
S0235	Lavendustin B Lavendustin B 抑制 HIV-1 integrase (IN) 与其同源的细胞辅助因子 lens epithelium-derived growth factor (LEDGF/p75) 的相互作用。Lavendustin B 是 Tyrosine Kinase 的抑制剂，也是 glucose transporter 1 (Glut1) 的竞争性抑制剂。

目录号	产品描述	文献引用	实验数据
S7931	STF-31 STF-31是一种选择性葡萄糖转运蛋白GLUT1抑制剂。	Cell Metab,2020, 31(3):564-579 Sci Adv,2020, 6;6(19):eaay9466 Theranostics,2020, 6;10(12):5259-5275	NP69 cells were transfected with LMP1 expression plasmid and treated with STF-31 or infected with lentivirus expressing shGlut-1 for 48 h. The cells were then lysed and subjected to Western blotting using specific antibodies against Glut-1 and cleaved caspase 3. β-Actin expression was used as the loading control.
S7927	WZB117 WZB117是GLUT1的抑制剂，它可以抑制肺癌细胞A549和乳腺癌MCF7细胞的细胞增殖，IC50约为10 μM。	Neurosci Bull,2021, 10.1007/s12264-020-00624-1 J Cell Physiol,2020, 10.1002 Nat Commun,2019, 10(1):3981
S8452	BAY-876 BAY-876是有效的、选择性的GLUT1抑制剂（IC50=0.002 μM），对GLUT1的选择性比对GLUT2, GLUT3和GLUT4的选择性高100倍。	SSRN,2021, 10.2139/ssrn.3862792 Biomaterials,2020, 239:119839 Elife,2020, 9e56749
S9636	DRB18 DRB18 是一种 pan-GLUT (glucose transporters) 的抑制剂，可高活性地抑制几种癌症类型的生长和增殖。
S5748	4′-Deoxyphlorizin 4'-Deoxyphlorizin is an inhibitor of the glucose transport system.
S0235	Lavendustin B Lavendustin B 抑制 HIV-1 integrase (IN) 与其同源的细胞辅助因子 lens epithelium-derived growth factor (LEDGF/p75) 的相互作用。Lavendustin B 是 Tyrosine Kinase 的抑制剂，也是 glucose transporter 1 (Glut1) 的竞争性抑制剂。