Phosphorylase

抑制剂选择性比较

Phosphorylase产品

所有产品(5) Phosphorylase抑制剂(4) Phosphorylase激活剂(1)

目录号	产品描述	文献引用	实验数据
S2717	CP-91149 CP-91149在有葡萄糖存在时，选择性抑制糖原磷酸化酶，IC50为0.13 μM，在无葡萄糖存在时，作用效果低5到10倍。	Cells, 2020, 9(3) Cells, 2020, 9(3)E715 J Biol Chem, 2020, 295(1):83-98	C, experimental design illustrating the time points in which PYGL inhibitor CP-91149 (GPi) and 2DG were added to the groups depicted in D to J. D, representative images of cell invasion through the Boyden chamber from control, 2DG and recovery GBM1 treated with GPi or DMSO. E to G, comparison of the invasive capacity of EV or shG6PC in the presence or absence of GPi.
S0031	Ingliforib Ingliforib(CP 368296)是一种糖原磷酸化酶(glycogen phosphorylase, GP)抑制剂，对肝、肌肉和脑糖原磷酸化酶的IC50值分别为52 nM、352 nM和150 nM，具有心脏保护活性。
S6510	Iso-H7 dihydrochloride Iso-H7 dihydrochloride是磷酸激酶C抑制剂。
S3731	Tipiracil hydrochloride Tipiracil (MA-1)是一种 thymidine phosphorylase的抑制剂，该酶可将三氟吡啶降解为三氟胸苷。它与三氟吡啶的组合可增加三氟吡啶的生物利用度。	Cell Mol Immunol, 2022, 10.1038/s41423-022-00842-9
S2045	Doxifluridine Doxifluridine (5'-DFUR, AMC 0101) 是一种胸苷磷酸化酶激活剂，作用于PC9-DPE2细胞，IC50为0.62 μM。	Cell Metab, 2019, 29(5):1217-1231 Oncotarget, 2018, Oncotarget

目录号	产品描述	文献引用	实验数据
S2717	CP-91149 CP-91149在有葡萄糖存在时，选择性抑制糖原磷酸化酶，IC50为0.13 μM，在无葡萄糖存在时，作用效果低5到10倍。	Cells,2020, 9(3) Cells,2020, 9(3)E715 J Biol Chem,2020, 295(1):83-98	C, experimental design illustrating the time points in which PYGL inhibitor CP-91149 (GPi) and 2DG were added to the groups depicted in D to J. D, representative images of cell invasion through the Boyden chamber from control, 2DG and recovery GBM1 treated with GPi or DMSO. E to G, comparison of the invasive capacity of EV or shG6PC in the presence or absence of GPi.
S0031	Ingliforib Ingliforib(CP 368296)是一种糖原磷酸化酶(glycogen phosphorylase, GP)抑制剂，对肝、肌肉和脑糖原磷酸化酶的IC50值分别为52 nM、352 nM和150 nM，具有心脏保护活性。
S6510	Iso-H7 dihydrochloride Iso-H7 dihydrochloride是磷酸激酶C抑制剂。
S3731	Tipiracil hydrochloride Tipiracil (MA-1)是一种 thymidine phosphorylase的抑制剂，该酶可将三氟吡啶降解为三氟胸苷。它与三氟吡啶的组合可增加三氟吡啶的生物利用度。	Cell Mol Immunol,2022, 10.1038/s41423-022-00842-9

目录号

产品描述

文献引用

实验数据

S2045

Doxifluridine

Doxifluridine (5'-DFUR, AMC 0101) 是一种胸苷磷酸化酶激活剂，作用于PC9-DPE2细胞，IC50为0.62 μM。

Cell Metab, 2019, 29(5):1217-1231

Oncotarget, 2018, Oncotarget