Phosphorylase
- 抑制剂选择性比较
- 溶解性比较
| 目录号 | 产品目录 | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | 酒精 | ||
| S2717 | CP-91149 | <1 mg/mL | 80 mg/mL | <1 mg/mL |
| S3731 | Tipiracil hydrochloride | 55 mg/mL | 8 mg/mL | <1 mg/mL |
| S2045 | Doxifluridine | 49 mg/mL | 49 mg/mL | <1 mg/mL |
- Phosphorylase抑制剂（3）
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S2717 |
CP-91149CP-91149在有葡萄糖存在时，选择性抑制糖原磷酸化酶，IC50为0.13 μM，在无葡萄糖存在时，作用效果低5到10倍。 |
C, experimental design illustrating the time points in which PYGL inhibitor CP-91149 (GPi) and 2DG were added to the groups depicted in D to J. D, representative images of cell invasion through the Boyden chamber from control, 2DG and recovery GBM1 treated with GPi or DMSO. E to G, comparison of the invasive capacity of EV or shG6PC in the presence or absence of GPi. |
|
| S3731 |
Tipiracil hydrochlorideTipiracil is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine. |
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| S2045 |
DoxifluridineDoxifluridine 是一种胸苷磷酸化酶激活剂，作用于PC9-DPE2细胞，IC50为0.62 μM。 |
