AF488 Anti-Human CD45RO (UCHL1) mAb
别名: null
CD45RO is a 180 kDa isoform of the CD45 molecule, also known as the Leukocyte Common Antigen. It is a type I transmembrane glycoprotein with cytoplasmic protein tyrosine phosphatase activity involved in signal transduction. Unlike other CD45 isoforms, CD45RO lacks the amino acid sequences encoded by the variable exons A, B, and C. It is expressed on most thymocytes, activated T cells, memory T cells, granulocytes, and monocytes, and on a subset of resting T cells. CD45RO and CD45RA mark largely distinct populations within resting peripheral T cells, demonstrating functional and phenotypic heterogeneity within CD4 and CD8 T cell subsets. CD45RO also interacts with CD22.
CAS: null
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生物活性
| 产品描述 | CD45RO is a 180 kDa isoform of the CD45 molecule, also known as the Leukocyte Common Antigen. It is a type I transmembrane glycoprotein with cytoplasmic protein tyrosine phosphatase activity involved in signal transduction. Unlike other CD45 isoforms, CD45RO lacks the amino acid sequences encoded by the variable exons A, B, and C. It is expressed on most thymocytes, activated T cells, memory T cells, granulocytes, and monocytes, and on a subset of resting T cells. CD45RO and CD45RA mark largely distinct populations within resting peripheral T cells, demonstrating functional and phenotypic heterogeneity within CD4 and CD8 T cell subsets. CD45RO also interacts with CD22. |
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化学信息&溶解度
| 分子量 | 180 kDa | 分子式 | |
| CAS号 | SDF | -- | |
| 储存条件(自收到货起) | Store at 4°C in the dark to avoid freeze-thaw cycles | ||
|
体内溶解配方 现配现用，请按从左到右的顺序依次添加，澄清后再加入下一溶剂 |
动物体内配方计算器 | |||||
实验计算
动物体内配方计算器（澄清溶液）
第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）
mg/kg
g
μL
只
第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）
% DMSO
%
% Tween 80
% ddH2O
%DMSO
%
计算结果：
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于μL DMSO溶液（母液浓度mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；
体内配方配制方法：取μL DMSO母液，加入μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入μL ddH2O，混匀澄清。
体内配方配制方法：取μL DMSO母液，加入μL Corn oil，混匀澄清。
注意：1. 首先保证母液是澄清的；
2.一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
技术支持
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