APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb
别名: CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
CD152, also known as CTLA-4 (Cytolytic T Lymphocyte-Associated Antigen 4), is a molecule transiently expressed on activated CD28+ T cells. It binds to CD80 and CD86 on antigen-presenting cells (APCs) with high avidity, delivering a negative regulatory signal to the T cell. It has also been shown that CTLA-4 is expressed on B cells when cultured with activated T cells, indicating a role in regulating the B-cell response. Additionally, CD152 is expressed on regulatory T (Treg) cells. The BNI3 monoclonal antibody specifically binds to human CTLA-4 and can be used to study its role in T-cell proliferation and regulation.
CAS: null
APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb相关产品
| 相关靶点 | CD38 CD45 CD39 CD11 CD88 CD73 | 点击展开 |
|---|---|---|
| 相关产品 | CD38 inhibitor 1 (compound 78c) Anti-CD83 SodiuM Metatungstate NQ301 LY-3475070 Relatlimab (anti-LAG-3) | 点击展开 |
| 相关化合物库 | 激酶抑制剂库 FDA药物库 天然产物库 已知活性药物库-I 高选择性抑制剂库 | 点击展开 |
生物活性
| 产品描述 | CD152, also known as CTLA-4 (Cytolytic T Lymphocyte-Associated Antigen 4), is a molecule transiently expressed on activated CD28+ T cells. It binds to CD80 and CD86 on antigen-presenting cells (APCs) with high avidity, delivering a negative regulatory signal to the T cell. It has also been shown that CTLA-4 is expressed on B cells when cultured with activated T cells, indicating a role in regulating the B-cell response. Additionally, CD152 is expressed on regulatory T (Treg) cells. The BNI3 monoclonal antibody specifically binds to human CTLA-4 and can be used to study its role in T-cell proliferation and regulation. |
|---|
化学信息&溶解度
| 分子量 | 42 kDa | 分子式 | |
| CAS号 | SDF | -- | |
| 储存条件(自收到货起) | Store at 4°C in the dark to avoid freeze-thaw cycles | ||
|
体内溶解配方 现配现用，请按从左到右的顺序依次添加，澄清后再加入下一溶剂 |
动物体内配方计算器 | |||||
实验计算
动物体内配方计算器（澄清溶液）
第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）
mg/kg
g
μL
只
第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）
% DMSO
%
% Tween 80
% ddH2O
%DMSO
%
计算结果：
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于μL DMSO溶液（母液浓度mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；
体内配方配制方法：取μL DMSO母液，加入μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入μL ddH2O，混匀澄清。
体内配方配制方法：取μL DMSO母液，加入μL Corn oil，混匀澄清。
注意：1. 首先保证母液是澄清的；
2.一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
技术支持
在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。
如果有其他问题，请给我们留言。
* 必填项
Tags: buy APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb | APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb supplier | purchase APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb | APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb cost | APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb manufacturer | order APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb | APC-Cy7 Anti-Human CD152/CTLA-4 (BNI3) mAb distributor
