AMPA receptor 选择性抑制剂 | 激动剂 | 拮抗剂 | 调节剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S2860 IEM 1754 2HBr

IEM 1754 2HBr是一种选择性AMPA/kainate受体抑制剂,作用于GluR1GluR3IC50为6 μM。

Selective GluR1, IC50: 6 μM; GluR3, IC50: 6 μM
S3070 Piracetam

Piracetam是神经递质氨基丁酸(GABA)的一种环状衍生物,用于治疗一系列认知障碍。

Selective
S6804 CX546

CX546, a prototypical ampakine agent, is a selective positive AMPA receptor modulator.

Selective
S2434 IDRA-21

IDRA-21 is a partial allosteric modulator of AMPA receptor desensitization. IDRA-21 is a potent cognition-enhancing drug virtually devoid of neurotoxic liability.

Selective
S4716 Evans Blue

Evans Blue是突触泡谷氨酸吸收的有效抑制剂,同时也是一种AMPA/kainate受体拮抗剂。

Selective
S6906 Capric acid

Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Selective
S9686 NBQX (FG9202)

NBQX (FG9202, NNC 079202) is a highly selective and competitive antagonist of AMPA receptor (AMPAR) with anti-epileptic effect.

Selective
S0165 Ampalex (CX-516)

CX-516 (Ampalex) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator. CX-516 (Ampalex) can be used as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).

Selective