• Carbonic Anhydrase I
  • Carbonic Anhydrase II
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase IX
  • Carbonic Anhydrase XII

Carbonic Anhydrase II 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S1375 Dorzolamide HCl Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. Selective Carbonic anhydrase II, Ki: 1.9 nM
S3178 Brinzolamide Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Selective CAII, IC50: 3.19 nM
S4039 Methazolamide Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Pan hCAII, Ki: 14 nM
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