LDHB 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6675 (R)-GNE-140

(R)-GNE-140 is a selective inhibitor of the LDHA and LDHB with IC50s of 3 nM and 5 nM, respectively. The R enantiomer of GNE-140 is 18-fold more potent than S enantiomer.

Pan LDHB, IC50: 5 nM
S8590 GSK 2837808A

GSK2837808A is a selective LDHA (lactate dehydrogenase A) inhibitor with IC50 of 2.6 nM and 43 nM for hLDHA and hLDHB, respectively.

Pan hLDHB, IC50: 43 nM