• MLKL
  • MLK1
  • MLK2
  • MLK3

MLK2 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S7343 URMC-099 URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy. Pan MLK2, IC50: 42 nM
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