• serine/threonine kinase
  • STK
  • WNK
  • DCLK
  • GCN
  • GAK
  • SRPK
  • PASK
  • BUB1

serine/threonine-kinase 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S1460 SP600125 SP600125 (Nsc75890) is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc. SP600125 is also a broad‐spectrum inhibitor of serine/threonine kinases including Aurora kinase AFLT3 and TRKA with of IC50 of 60 nM, 90 nM and Selective
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