MMP
MMP产品
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S7155 |
Batimastat (BB-94)Batimastat (BB-94)是一种有效的,广谱matrix metalloprotease (MMP)(基质金属蛋白酶)抑制剂,作用于MMP-1, MMP-2, MMP-9, MMP-7和MMP-3,IC50分别为3 nM, 4 nM, 4 nM, 6 nM和20 nM。 |
![]() ![]() Proliferation indices of SU-pcGBM2 cells exposed to plain medium (aCSF) or active conditioned medium generated in the presence or absence of pan-MMP inhibitor (BAT).
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S8072 |
NSC 405020NSC 405020是一种MT1-MMP抑制剂,直接与MT1-MMP的PEX区域相互作用,影响PEX二聚体化,但不影响MT1-MMP的催化活性。 |
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S4163 |
Doxycycline HyclateDoxycycline是四环素抗生素组的一个成员,通常用于治疗各种感染。还是MMP抑制剂。 |
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S7157 |
Ilomastat (GM6001, Galardin)Ilomastat (GM6001, Galardin)是一种广谱matrix metalloprotease (MMP)(基质金属蛋白酶)抑制剂,作用于MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14,和MMP-26,Ki分别为0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM,和0.36 nM。 |
![]() ![]() GM6001 inhibits MMP-7 and −10 mRNA expressions in Aurora-A stable cells in HNC. The mRNA expression levels of MMP-7 and −10 were examined by Q-RT-PCR in FaDu/vehicle, and FaDu/Aurora-A transfectants treated with DMSO or GM6001 in a dose-dependent manner. Statistical analysis: **p < 0.01, ***p < 0.001. |
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S3309New |
SolasodineSolasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) 是一种存在于茄科植物中的有毒的生物碱化合物。Solasodine 可降低 matrix metalloproteinase-2 (MMP-2)、MMP-9 和 matrix metalloproteinase (EMMPRIN) 的细胞外诱导剂的mRNA水平,但会增加 reversion-inducing cysteine-rich protein with kazal motifs (RECK)。Solasodine 下调致癌的 microRNA-21 (miR-21),已知其靶向RECK。Solasodine 还可以减少 PI3K/Akt 信号传导途径并下调miR-21的表达。 |
||
S0923New |
Isoliquiritin apiosideIsoliquiritin apioside (ISLA, ILA) 是一种分离自 Glycyrrhizae radix rhizome (GR) 的成分,可显著地降低PMA诱导的 matrix metalloproteinase (MMP) 的活性增加并抑制了PMA-诱导 mitogen-activated protein kinase (MAPK) 和 NF-κB 的活化。Isoliquiritin apioside 在恶性癌细胞和EC中具有抗转移和抗血管生成的能力,并且没有细胞毒性。 |
||
S8966New |
T-5224T-5224 是一种转录因子 c-Fos/activator protein (AP)-1 的选择性抑制剂,并具有抗炎作用。T-5224 可特异性地抑制 c-Fos/c-Jun 的DNA结合活性和 IL-1β 诱导的 Mmp-3、Mmp-13 和 Adamts-5 转录的上调。 |
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S0769New |
MMP-9-IN-1MMP-9-IN-1 是一种 matrix metalloproteinase-9 (MMP-9) 的特异性抑制剂。MMP-9-IN-1 可选择性地靶向MMP-9的血红素(PEX)域,Kd值为2.1 μM。 |
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S0752New |
AUDAAUDA (compound 43) 是一种有效的 soluble epoxide hydrolase (sEH) 的抑制剂,对小鼠sEH和人sEH的IC50值分别为18 nM和69 nM。AUDA具有抗炎活性,可降低MMP-9、IL-1β、TNF-α 和 TGF-β。AUDA还可下调 Smad3 和 p38 信号通路。 |
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S6830New |
o-Phenanthrolineo-Phenanthroline (1,10-Phenanthroline, phen) 是一种低氧模拟药物,一种非特异性的 matrix metalloproteinase (MMP) 抑制剂, 对于 Collagenase 的IC50值为110.5 μM。o-Phenanthroline 在人软骨细胞 (hChs) 软骨分化过程中以及在 TNFα/IL-1β 暴露后的外植体模型中可降低 MMP3 和 MMP13 mRNA的表达。o-Phenanthroline 也是一种金属 metal 螯合剂,可防止在链脲佐菌素处理的细胞中诱发染色体畸变,并与 Fe2+ 形成红色螯合物,在510 nm处最大程度地吸收。 |
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S0341New |
T-26cT-26c 是一种高效的 matrix metalloproteinase-13 (MMP-13) 的选择性抑制剂,IC50值为6.9 pM,选择性是其他相关金属酶的2600倍。 |
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S3610 |
CordycepinCordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. |
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S5696 |
JNJ0966JNJ0966是一种高度选择性化合物,抑制MMP-9 zymogen的激活以及随后具有催化活性的酶的生成。JNJ0966对MMP-1, MMP-2, MMP-3, MMP-9或MMP-14的催化活性没有影响,也不抑制MMP-2酶原的激活。 |
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S5543 |
1, 10-Phenanthroline monohydrate1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases. |
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S4884 |
Trans-ZeatinTrans-Zeatina ((E)-Zeatin) 是植物生长激素的成员之一,属于细胞分裂素,可调节细胞分裂、发育和营养加工。Trans-Zeatina ((E)-Zeatin) 可抑制UVB诱导的 MMP-1 表达,c-Jun 活化和 ERK,JNK 磷酸化和 p38 MAP kinases (MAPKs) 呈剂量依赖性。 |
||
S5752 |
AbametapirAbametapir (HA-44, BRN 0123183), the active ingredient of Xeglyze Lotion, is an inhibitor of metalloproteinases critical for louse survival and egg development. |
||
S4964 |
Lactobionic acidLactobionic acid (Galactosylgluconic acid) 是一种α-含氧酸,具有抗氧化活性,被用于皮肤药妆品的开发。 |
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S7430 |
SB-3CTSB-3CT 是高效选择性的gelatinase抑制剂,其作用于MMP-2和MMP-9的Ki分别为13.9 nM 和 600 nM。 |
![]() ![]() The matrix metalloproteinase 9(MMP9) inhibitor(SB-3CT) attenuated angiotensin II (Ang II)-induced cardiomyocyte hypertrophy in vitro. (A) Representative immunofluorescent (α-actinin) images of neonatal rat cardiomyocytes (NRCMs) in the presence or absence of MMP9 inhibitor that were administered PBS or Ang II for 48 h. Bar=200 μm. (B) Statistical results for the cell surface area (CSA) of NRCMs. (C-E) The relative mRNA expression levels of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and β-myosin heavy chain (β-MHC) in NRCMs in the presence or absence of MMP9 inhibitor that were administered PBS or Ang II for 48 h. The intensities were normalized to the levels of GAPDH mRNA with the value in the PBS group defined as 1. * P<0.05 versus the control group, # P<0.05 versus the Ang II group. n=6 samples per experimental group
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S9052 |
AurapteneAuraptene (7-geranyloxycoumarin)是源自柑橘类植物的天然香豆素,具有重要的药理特性,包括抗癌,抗炎,抗幽门螺杆菌,抗原毒性和神经保护作用。Auraptene 可抑制 matrix metalloproteinase 2 (MMP-2) 以及关键的炎症介质,包括 IL-6、IL-8 和 chemokine (C-C motif) ligand-5(CCL5)。 |
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S9386 |
Polygalacic acidPolygalacic acid 是从远志属植物(Polygala paenea L.)分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达,这些因子的表达由IL-1β诱导可显著增加,并呈现出剂量依赖性。 |
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S7156 |
Marimastat (BB-2516)Marimastat (BB-2516)是一种广谱的 matrix metalloprotease (MMP) 抑制剂,对 MMP-9,MMP-1,MMP-2,MMP-14 和 MMP-7 的 IC50 分别为 3 nM,5 nM,6 nM,9 nM 和 13 nM。Phase 3。 |
![]() ![]() (E, F) Uev1A mediates negative feedback of NF-κB signaling pathway is dependent on TACE activity. Forty-eight hours after transfection, the cells were pre-treated with BB-2516 (20 μM) for 1 h, followed by TNFα (40 ng/ml) treatment for 2 h. Cell was fixed and stained with antibodies against HA and p65. The same cells were also stained with DAPI to reveal nuclei. White arrows indicate UEV1A-overexpressed cells. (F) Quantitative analysis of the experiments shown in (E). Percentage of cells displaying nuclear p65 is shown for UEV1A- overexpressed or vector-transfected cells. Each sample contains about 1000 cells. The significance of differences was assessed by two-tailed Student's test (***P < 0.001).
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S2333 |
NobiletinNobiletin (Hexamethoxyflavone) 是O-甲基黄酮,是从柑橘果皮如橘子分离的一种黄酮类化合物。具有抗炎和抗肿瘤活性。 |
![]() ![]() NOB modulates Cps1 mRNA and protein expression. a Total protein extracts were prepared from liver samples collected from the four diet/treatment groups of wild-type mice at the indicated circadian time points (n = 3). Western blotting analysis was performed using anti-CPS1 antibody. RC regular chow, HFD high-fat diet, Veh vehicle, NOB Nobiletin. The results shown are representative of three independent experiments. See Additional file 1: Figure S1A for quantitative analysis. b Immunohistochemical staining of CPS1 in liver sections from mice with the indicated diet and treatment at ZT2. c Real-time RT-PCR analysis of Cps1 in liver samples collected as in (a). Data are presented as mean ± SEM (n = 3). Two-way ANOVA with Bonferroni post-hoc tests shows significant statistical differences between HFD.Veh and other three groups (p < 0.0001). d Western blotting analysis of protein lysates of liver samples collected at ZT 6 and 18 from mice with the indicated diet and treatment (n = 3). HPD indicates high-protein diet. The images shown to the left are representative of three independent experiments. Quantitation of Western blots was carried out and the results, presented as mean ± SEM, are shown in the lower panel. Two-way ANOVA with Bonferroni post-hoc tests, RC vs. HPD, ***p < 0.001. e Real-time qPCR analysis was carried out using total RNAs extracted from the liver samples described in (d). The results are presented as mean ± SEM. Two-way ANOVA with Bonferroni post-hoc tests, RC vs. HPD, *p < 0.05. |
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S7434 |
TAPI-1TAPI-1 是一种ADAM17/TACE抑制剂, 其对细胞因子受体有抑制作用。TAPI-1 也是 Matrix Metalloproteinase (MMP) 的抑制剂。 |
![]() ![]() (B) Florescent images of EpEX (green) and EpICD (red) in PK-15 cells, which were transfected by pSIN-fEpCAM-mCherry and treated with or without TAPI-1/DAPT. Nuclei were stained by Hoechst 33342 (blue). Scale bar, 25 μm.
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S5159 |
DoxycyclineDoxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum)是一种抗生素,用于治疗由细菌和原生动物引起的多种感染。Doxycycline 也是一种非特异性的 matrix metalloproteinase (MMP) 抑制剂。 |
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S5465 |
MorronisideMorroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. |
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S3288New |
AbsinthinAbsinthin (Absynthine) 是一种来自 Artemisia absinthium 的天然三萜内酯,具有抗炎特性。Absinthin (Absynthine) 可显著地增强 matrix metalloproteinase-8 (MMP-8) 的表达,并且是潜在的急性肺损伤(ALI)的候选治疗药物。 |
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S3781 |
Ginkgolide CGinkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9. |
目录号 | 产品描述 | 文献引用 | 实验数据 |
---|---|---|---|
S7155 |
Batimastat (BB-94)Batimastat (BB-94)是一种有效的,广谱matrix metalloprotease (MMP)(基质金属蛋白酶)抑制剂,作用于MMP-1, MMP-2, MMP-9, MMP-7和MMP-3,IC50分别为3 nM, 4 nM, 4 nM, 6 nM和20 nM。 |
![]() ![]() Proliferation indices of SU-pcGBM2 cells exposed to plain medium (aCSF) or active conditioned medium generated in the presence or absence of pan-MMP inhibitor (BAT).
|
|
S8072 |
NSC 405020NSC 405020是一种MT1-MMP抑制剂,直接与MT1-MMP的PEX区域相互作用,影响PEX二聚体化,但不影响MT1-MMP的催化活性。 |
||
S4163 |
Doxycycline HyclateDoxycycline是四环素抗生素组的一个成员,通常用于治疗各种感染。还是MMP抑制剂。 |
||
S7157 |
Ilomastat (GM6001, Galardin)Ilomastat (GM6001, Galardin)是一种广谱matrix metalloprotease (MMP)(基质金属蛋白酶)抑制剂,作用于MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14,和MMP-26,Ki分别为0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM,和0.36 nM。 |
![]() ![]() GM6001 inhibits MMP-7 and −10 mRNA expressions in Aurora-A stable cells in HNC. The mRNA expression levels of MMP-7 and −10 were examined by Q-RT-PCR in FaDu/vehicle, and FaDu/Aurora-A transfectants treated with DMSO or GM6001 in a dose-dependent manner. Statistical analysis: **p < 0.01, ***p < 0.001. |
|
S3309New |
SolasodineSolasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) 是一种存在于茄科植物中的有毒的生物碱化合物。Solasodine 可降低 matrix metalloproteinase-2 (MMP-2)、MMP-9 和 matrix metalloproteinase (EMMPRIN) 的细胞外诱导剂的mRNA水平,但会增加 reversion-inducing cysteine-rich protein with kazal motifs (RECK)。Solasodine 下调致癌的 microRNA-21 (miR-21),已知其靶向RECK。Solasodine 还可以减少 PI3K/Akt 信号传导途径并下调miR-21的表达。 |
||
S0923New |
Isoliquiritin apiosideIsoliquiritin apioside (ISLA, ILA) 是一种分离自 Glycyrrhizae radix rhizome (GR) 的成分,可显著地降低PMA诱导的 matrix metalloproteinase (MMP) 的活性增加并抑制了PMA-诱导 mitogen-activated protein kinase (MAPK) 和 NF-κB 的活化。Isoliquiritin apioside 在恶性癌细胞和EC中具有抗转移和抗血管生成的能力,并且没有细胞毒性。 |
||
S8966New |
T-5224T-5224 是一种转录因子 c-Fos/activator protein (AP)-1 的选择性抑制剂,并具有抗炎作用。T-5224 可特异性地抑制 c-Fos/c-Jun 的DNA结合活性和 IL-1β 诱导的 Mmp-3、Mmp-13 和 Adamts-5 转录的上调。 |
||
S0769New |
MMP-9-IN-1MMP-9-IN-1 是一种 matrix metalloproteinase-9 (MMP-9) 的特异性抑制剂。MMP-9-IN-1 可选择性地靶向MMP-9的血红素(PEX)域,Kd值为2.1 μM。 |
||
S0752New |
AUDAAUDA (compound 43) 是一种有效的 soluble epoxide hydrolase (sEH) 的抑制剂,对小鼠sEH和人sEH的IC50值分别为18 nM和69 nM。AUDA具有抗炎活性,可降低MMP-9、IL-1β、TNF-α 和 TGF-β。AUDA还可下调 Smad3 和 p38 信号通路。 |
||
S6830New |
o-Phenanthrolineo-Phenanthroline (1,10-Phenanthroline, phen) 是一种低氧模拟药物,一种非特异性的 matrix metalloproteinase (MMP) 抑制剂, 对于 Collagenase 的IC50值为110.5 μM。o-Phenanthroline 在人软骨细胞 (hChs) 软骨分化过程中以及在 TNFα/IL-1β 暴露后的外植体模型中可降低 MMP3 和 MMP13 mRNA的表达。o-Phenanthroline 也是一种金属 metal 螯合剂,可防止在链脲佐菌素处理的细胞中诱发染色体畸变,并与 Fe2+ 形成红色螯合物,在510 nm处最大程度地吸收。 |
||
S0341New |
T-26cT-26c 是一种高效的 matrix metalloproteinase-13 (MMP-13) 的选择性抑制剂,IC50值为6.9 pM,选择性是其他相关金属酶的2600倍。 |
||
S3610 |
CordycepinCordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. |
||
S5696 |
JNJ0966JNJ0966是一种高度选择性化合物,抑制MMP-9 zymogen的激活以及随后具有催化活性的酶的生成。JNJ0966对MMP-1, MMP-2, MMP-3, MMP-9或MMP-14的催化活性没有影响,也不抑制MMP-2酶原的激活。 |
||
S5543 |
1, 10-Phenanthroline monohydrate1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases. |
||
S4884 |
Trans-ZeatinTrans-Zeatina ((E)-Zeatin) 是植物生长激素的成员之一,属于细胞分裂素,可调节细胞分裂、发育和营养加工。Trans-Zeatina ((E)-Zeatin) 可抑制UVB诱导的 MMP-1 表达,c-Jun 活化和 ERK,JNK 磷酸化和 p38 MAP kinases (MAPKs) 呈剂量依赖性。 |
||
S5752 |
AbametapirAbametapir (HA-44, BRN 0123183), the active ingredient of Xeglyze Lotion, is an inhibitor of metalloproteinases critical for louse survival and egg development. |
||
S4964 |
Lactobionic acidLactobionic acid (Galactosylgluconic acid) 是一种α-含氧酸,具有抗氧化活性,被用于皮肤药妆品的开发。 |
||
S7430 |
SB-3CTSB-3CT 是高效选择性的gelatinase抑制剂,其作用于MMP-2和MMP-9的Ki分别为13.9 nM 和 600 nM。 |
![]() ![]() The matrix metalloproteinase 9(MMP9) inhibitor(SB-3CT) attenuated angiotensin II (Ang II)-induced cardiomyocyte hypertrophy in vitro. (A) Representative immunofluorescent (α-actinin) images of neonatal rat cardiomyocytes (NRCMs) in the presence or absence of MMP9 inhibitor that were administered PBS or Ang II for 48 h. Bar=200 μm. (B) Statistical results for the cell surface area (CSA) of NRCMs. (C-E) The relative mRNA expression levels of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and β-myosin heavy chain (β-MHC) in NRCMs in the presence or absence of MMP9 inhibitor that were administered PBS or Ang II for 48 h. The intensities were normalized to the levels of GAPDH mRNA with the value in the PBS group defined as 1. * P<0.05 versus the control group, # P<0.05 versus the Ang II group. n=6 samples per experimental group
|
|
S9052 |
AurapteneAuraptene (7-geranyloxycoumarin)是源自柑橘类植物的天然香豆素,具有重要的药理特性,包括抗癌,抗炎,抗幽门螺杆菌,抗原毒性和神经保护作用。Auraptene 可抑制 matrix metalloproteinase 2 (MMP-2) 以及关键的炎症介质,包括 IL-6、IL-8 和 chemokine (C-C motif) ligand-5(CCL5)。 |
||
S9386 |
Polygalacic acidPolygalacic acid 是从远志属植物(Polygala paenea L.)分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达,这些因子的表达由IL-1β诱导可显著增加,并呈现出剂量依赖性。 |
||
S7156 |
Marimastat (BB-2516)Marimastat (BB-2516)是一种广谱的 matrix metalloprotease (MMP) 抑制剂,对 MMP-9,MMP-1,MMP-2,MMP-14 和 MMP-7 的 IC50 分别为 3 nM,5 nM,6 nM,9 nM 和 13 nM。Phase 3。 |
![]() ![]() (E, F) Uev1A mediates negative feedback of NF-κB signaling pathway is dependent on TACE activity. Forty-eight hours after transfection, the cells were pre-treated with BB-2516 (20 μM) for 1 h, followed by TNFα (40 ng/ml) treatment for 2 h. Cell was fixed and stained with antibodies against HA and p65. The same cells were also stained with DAPI to reveal nuclei. White arrows indicate UEV1A-overexpressed cells. (F) Quantitative analysis of the experiments shown in (E). Percentage of cells displaying nuclear p65 is shown for UEV1A- overexpressed or vector-transfected cells. Each sample contains about 1000 cells. The significance of differences was assessed by two-tailed Student's test (***P < 0.001).
|
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S2333 |
NobiletinNobiletin (Hexamethoxyflavone) 是O-甲基黄酮,是从柑橘果皮如橘子分离的一种黄酮类化合物。具有抗炎和抗肿瘤活性。 |
![]() ![]() NOB modulates Cps1 mRNA and protein expression. a Total protein extracts were prepared from liver samples collected from the four diet/treatment groups of wild-type mice at the indicated circadian time points (n = 3). Western blotting analysis was performed using anti-CPS1 antibody. RC regular chow, HFD high-fat diet, Veh vehicle, NOB Nobiletin. The results shown are representative of three independent experiments. See Additional file 1: Figure S1A for quantitative analysis. b Immunohistochemical staining of CPS1 in liver sections from mice with the indicated diet and treatment at ZT2. c Real-time RT-PCR analysis of Cps1 in liver samples collected as in (a). Data are presented as mean ± SEM (n = 3). Two-way ANOVA with Bonferroni post-hoc tests shows significant statistical differences between HFD.Veh and other three groups (p < 0.0001). d Western blotting analysis of protein lysates of liver samples collected at ZT 6 and 18 from mice with the indicated diet and treatment (n = 3). HPD indicates high-protein diet. The images shown to the left are representative of three independent experiments. Quantitation of Western blots was carried out and the results, presented as mean ± SEM, are shown in the lower panel. Two-way ANOVA with Bonferroni post-hoc tests, RC vs. HPD, ***p < 0.001. e Real-time qPCR analysis was carried out using total RNAs extracted from the liver samples described in (d). The results are presented as mean ± SEM. Two-way ANOVA with Bonferroni post-hoc tests, RC vs. HPD, *p < 0.05. |
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S7434 |
TAPI-1TAPI-1 是一种ADAM17/TACE抑制剂, 其对细胞因子受体有抑制作用。TAPI-1 也是 Matrix Metalloproteinase (MMP) 的抑制剂。 |
![]() ![]() (B) Florescent images of EpEX (green) and EpICD (red) in PK-15 cells, which were transfected by pSIN-fEpCAM-mCherry and treated with or without TAPI-1/DAPT. Nuclei were stained by Hoechst 33342 (blue). Scale bar, 25 μm.
|
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S5159 |
DoxycyclineDoxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum)是一种抗生素,用于治疗由细菌和原生动物引起的多种感染。Doxycycline 也是一种非特异性的 matrix metalloproteinase (MMP) 抑制剂。 |
||
S5465 |
MorronisideMorroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. |
目录号 | 产品描述 | 文献引用 | 实验数据 |
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S3288New |
AbsinthinAbsinthin (Absynthine) 是一种来自 Artemisia absinthium 的天然三萜内酯,具有抗炎特性。Absinthin (Absynthine) 可显著地增强 matrix metalloproteinase-8 (MMP-8) 的表达,并且是潜在的急性肺损伤(ALI)的候选治疗药物。 |
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S3781 |
Ginkgolide CGinkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9. |