Paclitaxel (NSC 125973)

For research use only. Not for use in humans.

目录号:S1150 别名: PTX, Taxol, Onxal, Abraxane 中文名称:紫杉醇

Paclitaxel (NSC 125973) Chemical Structure

CAS No. 33069-62-4

Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane)是一种microtubule聚合物稳定剂,在人内皮细胞中IC50为0.1 pM。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 749.07 现货
RMB 571.49 现货
RMB 2235.46 现货
RMB 3849.3 现货
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客户使用Selleck生产的Paclitaxel (NSC 125973)发表文献290篇:

产品安全说明书

Antineoplastic and Immunosuppressive Antibiotics抑制剂选择性比较

生物活性

产品描述 Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane)是一种microtubule聚合物稳定剂,在人内皮细胞中IC50为0.1 pM。
特性 Paclitaxel 是有丝分裂抑制剂。
靶点
Microtubule (human endothelial cells) [1]
0.1 pM
体外研究

Paclitaxel在104到 105倍更高浓度时,抑制非内皮性人类细胞,IC50 为1 nM -10 nM。Paclitaxel选择性抑制细胞增殖,具有种属特异性,在Paclitaxel极低浓度时,小鼠内皮细胞对 Paclitaxel不敏感。 极低浓度Paclitaxel抑制 人类内皮细胞,但是不影响细胞微管结构,且处理的细胞在 G2/M 期没有出现细胞周期停滞和凋亡,说明这是一种新型尚未查明的作用机制。在体外血管生成实验中,在三维纤维蛋白基质中,极低浓度Paclitaxel阻断人类内皮细胞形成芽管。[1] 在SMF存在时, Paclitaxel 作用于 K562 细胞的有效浓度从50 ng/ml降低到 10 ng/ml。在有或无SMF时,Paclitaxel 使K562 细胞周期停滞与DNA损伤相关。[2] Paclitaxel单独处理四种细胞系,包括A549 细胞,H358, H1395 细胞和H1666 细胞,抑制CDK1,这种作用存在时间依赖性。[3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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MZ1-PC M3PtVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUKyTJBrUUN3MDC9JFAvODByN{K5OEDPxE1? MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
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JVM-3 NY\5OWFHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxKD1iMkCuPFk5PSEQvF2= M1TYbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
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COLO205 NX35XHFJS3m2b4TvfIlkcXS7IHHzd4F6 M2qxU2dKPTBiPTCwMlAxOTd4IN88US=> NUnYZ4NHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{mwPFk2OCd-N{mwPFk2ODxxYU6=
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OVCAR-3 NXjteVBES3m2b4TvfIlkcXS7IHHzd4F6 NUPQO|Z2T0l3MDC9JFAvODF7NzFOwG0> NHOzdWI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
NCI-H460 MnXwR5l1d3SxeHnjbZR6KGG|c3H5 MoCyS2k2OCB;IECuNFIyQSEQvF2= NEjvPVk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
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mammary carcinoma MXrDfZRwfG:6aXPpeJkh[XO|YYm= MWjJR|UxKD1iMD6yPVkh|ryP NGXlc5g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96MUiyOlk5Lz56MUiyOlk5RC:jPh?=
NCI60 NVnpWZNDS3m2b4TvfIlkcXS7IHHzd4F6 NIPOXYJIUTVyIE2gNE4xODB4NTFOwG0> NV;tbGVuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUS2NVY2Oyd-OUS2NVY2OzxxYU6=
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murine leukemic P388 M{PZNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NE\qU4dIUTVyIE2gNE4xOTZizszN M164SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzl6N{O1PVcoRjl6N{O1PVc9N2F-
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MCF-7 M4nxb2N6fG:2b4jpZ4l1gSCjc4PhfS=> MX7FSFUxKD1iMD6wNFQh|ryP M1;oV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzM{O0OVY4Lz5zMUOzOFU3PzxxYU6=
uterine sarcoma (MES-SA) MnL0R5l1d3SxeHnjbZR6KGG|c3H5 NYrnfWlFUUN3MDC9JFAvODByMESg{txO NVHI[W1JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG3NlgyQTFpPkGxO|I5OTlzPD;hQi=>
nonsmall cell lung carcinoma (NCI-H460) MkTiR5l1d3SxeHnjbZR6KGG|c3H5 M1q2UWlEPTBiPTCwMlAxODF2IN88US=> Mm[3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5MkixPVEoRjFzN{K4NVkyRC:jPh?=
colon adenocarcinoma (HT-29) M{Lod2N6fG:2b4jpZ4l1gSCjc4PhfS=> M{LLSGlEPTBiPTCwMlAxODF4IN88US=> MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTd{OEG5NUc,OTF5MkixPVE9N2F-
prostate carcinoma (DU-145) NFzXPZZEgXSxdH;4bYNqfHliYYPzZZk> NFToco1KSzVyIE2gNE4xODR6OTFOwG0> M3TjSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVkyLz5zMUeyPFE6OTxxYU6=
SW626 M1PqN2N6fG:2b4jpZ4l1gSCjc4PhfS=> MnnnO|IhcA>? MojRTWM2OCB;IECuNFAxODFizszN NVHLfGxiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
Lu1 NIfidVJEgXSxdH;4bYNqfHliYYPzZZk> M3vPTlczKGh? NEfTNWhKSzVyIE2gNE4xOSEQvF2= M4nKSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
MCF7 NVvWXFhNS3m2b4TvfIlkcXS7IHHzd4F6 M1GyUlczKGh? NIrkbZZKSzVyIE2gNE4xOiEQvF2= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
P388 NVrYVGNlS3m2b4TvfIlkcXS7IHHzd4F6 MX:3NkBp NHz6e4RKSzVyIE2gNE4xOiEQvF2= NVjDNIpxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
LNCAP M3\0[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MkXoO|IhcA>? NITwToJKSzVyIE2gNE4xOiEQvF2= Mnz1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
KB M4jsdmN6fG:2b4jpZ4l1gSCjc4PhfS=> M4nYPFczKGh? M1r2bGlEPTBiPTCwMlAzKM7:TR?= NYfMbmlIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
Col2 NESwfGVEgXSxdH;4bYNqfHliYYPzZZk> NETnU5E4OiCq MkO5TWM2OCB;IECuNFIh|ryP NUnsXXZjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
BC1 M17PWGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIi2W204OiCq MnTzTWM2OCB;IECuNFIh|ryP NWjyfXExRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
SK-MEL-2 NWjocmVFS3m2b4TvfIlkcXS7IHHzd4F6 NHrCXWw4OiCq M{C5TWlEPTBiPTCwMlA4KM7:TR?= MoLJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
L2987 NX;UOIFLS3m2b4TvfIlkcXS7IHHzd4F6 M4XmO2lEPTBiPTCwMlIh|ryP M4G4dlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{NESzO|g{Lz5zMkS0N|c5OzxxYU6=
colon adenocarcinoma RKO MVnDfZRwfG:6aXPpeJkh[XO|YYm= M2TET2lEPTBiPTCwMlAyKM7:TR?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjh3Mke2PEc,OTJ6NUK3Olg9N2F-
NCI-H460 M4i5dWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2fKbFQ5KGh? MXvJR|UxKD1iMD6wNFk2KM7:TR?= M1vqR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2Nkm1O|k5Lz5zNE[5OVc6QDxxYU6=
MCF7 NULvS4JvS3m2b4TvfIlkcXS7IHHzd4F6 NYTld29PPDhiaB?= MVHJR|UxKD1iMD6wNVEzKM7:TR?= MljOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR4OUW3PVgoRjF2Nkm1O|k5RC:jPh?=
SF268 M17rcWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXu0PEBp NV3CSpZ3UUN3MDC9JFAvODJzNzFOwG0> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDZ7NUe5PEc,OTR4OUW3PVg9N2F-
MDA-MB-231 NF:xTmREgXSxdH;4bYNqfHliYYPzZZk> MV[0PEBp NGfXUJFKSzVyIE2gNE4xODR3IN88US=> M1OzSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2OUi3NFUyLz5zNEm4O|A2OTxxYU6=
MCF7 M4fLTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NE[zS2k1QCCq M4T6OGlEPTBiPTCwMlAxPDlizszN NF\kcVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
A2780 NWr5RoZFS3m2b4TvfIlkcXS7IHHzd4F6 NH\tZWM1QCCq NX3QZ5N1UUN3MDC9JFAvODJ3IN88US=> NGnYZo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
PC3 M4T2N2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVy0PEBp NGrQSZBKSzVyIE2gNE4xPzdizszN MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
MCF7 MWPDfZRwfG:6aXPpeJkh[XO|YYm= NW\tS5Z{PzJiaB?= Mn3OTWM2OCB;IECuNFAyPCEQvF2= NFXFXpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2Pid-MUS5PFcxPTZ:L3G+
multidrug-resistant MCF7 MmXyR5l1d3SxeHnjbZR6KGG|c3H5 MXy3NkBp Ml:1TWM2OCB;IECuN|U1KM7:TR?= M3r2W|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2OUi3NFU3Lz5zNEm4O|A2PjxxYU6=
PC3 NV7oPFRsS3m2b4TvfIlkcXS7IHHzd4F6 M3LmXlQ5KGh? M4HQbGlEPTBiPTCwMlAyPiEQvF2= NXfkSYp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODJpPkG1NFQ{PDB{PD;hQi=>
Hep3B NILRN4REgXSxdH;4bYNqfHliYYPzZZk> NGDyV4k1QCCq MoDhTWM2OCB;IECuNFMyKM7:TR?= MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwNkc,OTVyNEO0NFI9N2F-
NCI-H460 MoTRR5l1d3SxeHnjbZR6KGG|c3H5 MkDMOFghcA>? MYLJR|UxKD1iMD6wNFk2KM7:TR?= NG\LU4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPCd-MUWwOFM1ODR:L3G+
MCF7 NIW0NVJEgXSxdH;4bYNqfHliYYPzZZk> NYHXWW5bPDhiaB?= MkfGTWM2OCB;IECuNFEyOiEQvF2= NFvub5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPCd-MUWwOFM1ODR:L3G+
SF268 NHHv[nJEgXSxdH;4bYNqfHliYYPzZZk> NWjnXnFbPDhiaB?= MVnJR|UxKD1iMD6wNlE4KM7:TR?= MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwOEc,OTVyNEO0NFQ9N2F-
KB MXXDfZRwfG:6aXPpeJkh[XO|YYm= MWHFSFUxKD1iMD6wNFA1KM7:TR?= NX3RbHNWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
Lu1 M3jnPWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWPFSFUxKD1iMD6wNFIh|ryP M3PNOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA4Lz5zNUC0N|QxPzxxYU6=
LNCAP MVjDfZRwfG:6aXPpeJkh[XO|YYm= M2LqOmVFPTBiPTCwMlAxPSEQvF2= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwO{c,OTVyNEO0NFc9N2F-
RPE1 Mlq1R5l1d3SxeHnjbZR6KGG|c3H5 M1j5XGVFPTBiPTCwMlAzOyEQvF2= NXPIWIlnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
Col2 MYXDfZRwfG:6aXPpeJkh[XO|YYm= M{jafmVFPTBiPTCwMlA1PiEQvF2= NGnQXIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPyd-MUWwOFM1ODd:L3G+
T47D NXPJVG9ZSXCxcITvd4l{KGG|c3H5 MnzJNlQhcA>? NEjsPJBGSzVyIE2gNE4xOyEQvF2= NIS1dpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUW2OlMxOCd-MUW1OlY{ODB:L3G+
DLD1 NELyOFlCeG:ydH;zbZMh[XO|YYm= MU[yOEBp M2LvPGVEPTBiPTCwMlA4PSEQvF2= M162cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NU[2N|AxLz5zNUW2OlMxODxxYU6=
H1299 Ml\5RZBweHSxc3nzJIF{e2G7 NGTWT3UzPCCq M1vWRmVEPTBiPTCwMlE3OyEQvF2= M2X3WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NU[2N|AxLz5zNUW2OlMxODxxYU6=
VA13 NYPoTld4S3m2b4TvfIlkcXS7IHHzd4F6 NIDyW5Y1QCCq NF3QT5VKSzVyIE2gNE4xODVizszN MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd|MEK0N{c,OTV5M{CyOFM9N2F-
WI 38 MWLDfZRwfG:6aXPpeJkh[XO|YYm= NYfFVHF{PDhiaB?= NH2yOGxKSzVyIE2gNE4xPCEQvF2= NY\MZ3k4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3N|AzPDNpPkG1O|MxOjR|PD;hQi=>
Hep G2 MlHmR5l1d3SxeHnjbZR6KGG|c3H5 Mo[wOFghcA>? M1HQfGlEPTBiPTC4MlEh|ryP MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd|MEK0N{c,OTV5M{CyOFM9N2F-
A549 M4TRUGN6fG:2b4jpZ4l1gSCjc4PhfS=> M{XzWlQ5KGh? NWX4TpptUUN3MDC9JFEvOjVizszN NU\NZ2pTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3PFc1PjBpPkG1O|g4PDZyPD;hQi=>
SKOV3 NIP2[ZNEgXSxdH;4bYNqfHliYYPzZZk> NGO0Ong1QCCq NFGze4lKSzVyIE2gNU4{PSEQvF2= M2Xve|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{i3OFYxLz5zNUe4O|Q3ODxxYU6=
KB MUHDfZRwfG:6aXPpeJkh[XO|YYm= MUGzJIRigXN? Mnn6TWM2OCB;IECuNFAyKM7:TR?= NFPvNHo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkCzPFU1PSd-MU[wN|g2PDV:L3G+
1A9 MYjDfZRwfG:6aXPpeJkh[XO|YYm= NGfse2Y{KGSjeYO= M3f3NGlEPTBiPTCwMlAxOiEQvF2= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjB|OEW0OUc,OTZyM{i1OFU9N2F-
HCT8 NXPI[o01S3m2b4TvfIlkcXS7IHHzd4F6 MX:zJIRigXN? MX\JR|UxKD1iMD6wNVMh|ryP M1PvXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
A431 NUHPWGVGS2WubDDjfYNt\SCjcoLld5Qh[XO|YYm= NVvs[XR[TUN3MDC9JFAvODB7IN88US=> M2\IbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4M{e3NVg4Lz5zNkO3O|E5PzxxYU6=
VA13 MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVG0PEBp NWTLUFBjUUN3MDC9JFAvODB2MzFOwG0> M3XUO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|IzLz5zNkS5PVMzOjxxYU6=
WI38 NVnQTo5oT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYS0PEBp Mon6TWM2OCB;IECuNFM1KM7:TR?= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
HepG2 NWrpN5ZjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFnHfHc1QCCq MVjJR|UxKD1iNj65JO69VQ>? NEjr[WI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkS5PVMzOid-MU[0PVk{OjJ:L3G+
Aro MYjDfZRwfG:6aXPpeJkh[XO|YYm= NGDQXFVKSzVyIE2gNE4xODB{IN88US=> M4n6eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
PT45 M4D4e2N6fG:2b4jpZ4l1gSCjc4PhfS=> MlTjTWM2OCB;IECuNFA2KM7:TR?= Mn\UQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
A549 MVrDfZRwfG:6aXPpeJkh[XO|YYm= NUTaToxxUUN3MDC9JFAvODB4IN88US=> NE\Pfnc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
MCF7 MlPiR5l1d3SxeHnjbZR6KGG|c3H5 NH7mbmRKSzVyIE2gNE4xODdizszN NF7qcGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
HeLa M3TEVWN6fG:2b4jpZ4l1gSCjc4PhfS=> NI\qPXBKSzVyIE2gNE4xODhizszN NEWyfJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
Ovcar3 M2i3dWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYnJR|UxKD1iMD6wNUDPxE1? M2jVVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
HT29 NYm1e3F2S3m2b4TvfIlkcXS7IHHzd4F6 MmDITWM2OCB;IECuNFUh|ryP NWjTXVJVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
H295R M2L6XWN6fG:2b4jpZ4l1gSCjc4PhfS=> NEe3Um5KSzVyIE2gNE4xQCEQvF2= Mmi3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
BNL Mom1R5l1d3SxeHnjbZR6KGG|c3H5 M3\MOGlEPTBiPTCwMlIh|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
4T1 NHHDPZhEgXSxdH;4bYNqfHliYYPzZZk> NIfBToVKSzVyIE2gNE4zKM7:TR?= MnLLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
HepG2 MojlR5l1d3SxeHnjbZR6KGG|c3H5 Mnv2TWM2OCB;IECuN{DPxE1? MmPvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
U937 GTB MYHDfZRwfG:6aXPpeJkh[XO|YYm= M13BVVczKGh? NVPlOIloUUN3MDC9JFAvODB3OTFOwG0> Mmf3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3NkK4OFAoRjF4NU[yPFQxRC:jPh?=
RPMI 8226/s MmXJR5l1d3SxeHnjbZR6KGG|c3H5 NFfnbVk4OiCq NIrhSXRKSzVyIE2gNE4xODdizszN NF;WTIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkW2Nlg1OCd-MU[1OlI5PDB:L3G+
CEM/s NXPXWmZTS3m2b4TvfIlkcXS7IHHzd4F6 NYC1[lhTPzJiaB?= MWXJR|UxKD1iMD6wNFch|ryP MomyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3NkK4OFAoRjF4NU[yPFQxRC:jPh?=
VA13 M{OxOmN6fG:2b4jpZ4l1gSCjc4PhfS=> M{Hud2lEPTBiPTCwMlAxPTlizszN M2jQOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{K0PFQzLz5zNkeyOFg1OjxxYU6=
WI38 MmP4R5l1d3SxeHnjbZR6KGG|c3H5 MWLJR|UxKD1iMD6wOFY5KM7:TR?= MlXhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ5MkS4OFIoRjF4N{K0PFQzRC:jPh?=
HepG2 NHO1SZZEgXSxdH;4bYNqfHliYYPzZZk> M1P2dmlEPTBiPTC5MlQ6KM7:TR?= MnHCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ5MkS4OFIoRjF4N{K0PFQzRC:jPh?=
HT29 MnTGR5l1d3SxeHnjbZR6KGG|c3H5 MUnFR|UxKD1iMD6wNFYh|ryP Mn3QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ6N{C0NlgoRjF4OEewOFI5RC:jPh?=
K562 NEH4eGJEgXSxdH;4bYNqfHliYYPzZZk> M3TaT2VEPTBiPTCwMlAyPCEQvF2= NVm5bVhLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4O|A1OjhpPkG2PFcxPDJ6PD;hQi=>
MCF7 NXvDelRuS3m2b4TvfIlkcXS7IHHzd4F6 MmTzSWM2OCB;IECuNFM3KM7:TR?= MnO0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ6N{C0NlgoRjF4OEewOFI5RC:jPh?=
VA-13 NYLLfnZwS3m2b4TvfIlkcXS7IHHzd4F6 NX\4SnFtUUN3MDC9JFAvODB3IN88US=> MkfrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7M{O4OlgoRjF4OUOzPFY5RC:jPh?=
WI38 NFSxZ2lEgXSxdH;4bYNqfHliYYPzZZk> M1v0TGlEPTBiPTCwMlA1KM7:TR?= NFPXR3k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkmzN|g3QCd-MU[5N|M5Pjh:L3G+
VA13 MVzDfZRwfG:6aXPpeJkh[XO|YYm= Mm\1TWM2OCB;IECuNFA2KM7:TR?= M4jmSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5ME[3NVU2Lz5zN{C2O|E2PTxxYU6=
WI38 NITJR4REgXSxdH;4bYNqfHliYYPzZZk> M3LKdGlEPTBiPTCwMlA1KM7:TR?= NV;XZ4hxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUewOlcyPTVpPkG3NFY4OTV3PD;hQi=>
Hep G2 M1nTOGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWXJR|UxKD1iOD6xJO69VQ>? NFHsRnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C2O|E2PSd-MUewOlcyPTV:L3G+
TW01 MUTDfZRwfG:6aXPpeJkh[XO|YYm= NIC0fXdKSzVyIE2gNE4xODB|IN88US=> MmX2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MCF7 M{jyWWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXi0S2lnUUN3MDC9JFAvODByNTFOwG0> MkSyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MKN45 MULDfZRwfG:6aXPpeJkh[XO|YYm= NHXQc3dKSzVyIE2gNE4xODB3IN88US=> Mn;hQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MES-SA Ml\IR5l1d3SxeHnjbZR6KGG|c3H5 NYGw[IIzUUN3MDC9JFAvODByNTFOwG0> M4rlblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
HCT116 M1nORWN6fG:2b4jpZ4l1gSCjc4PhfS=> MUnJR|UxKD1iMD6wNFA3KM7:TR?= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
RPTEC M1TjW2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoP1TWM2OCB;IECuNFAxQSEQvF2= NFLCd4E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
Hep3B M17Vc2N6fG:2b4jpZ4l1gSCjc4PhfS=> NHXWbG1KSzVyIE2gNE4xODV2IN88US=> NWPGNVRSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexNVMzQDhpPkG3NVE{Ojh6PD;hQi=>
NCI-H226 Mnz6R5l1d3SxeHnjbZR6KGG|c3H5 Mn;vTWM2OCB;IECuNFA3QCEQvF2= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
A498 M1y2d2N6fG:2b4jpZ4l1gSCjc4PhfS=> NGTIZ2dKSzVyIE2gNE4xPjFizszN M3j1O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MDA435/LCC6 M2DUSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MmDyTWM2OCB;IECuNFAzQSEQvF2= NVXXcYpHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexOVQ2ODVpPkG3NVU1PTB3PD;hQi=>
multidrug resistant MDA435/LCC6 MnLPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlnFTWM2OCB;IECuNFA1QCEQvF2= NGWySJg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
P388 MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M{HTVmlEPTBiPTCwMlAzOiEQvF2= M4WwdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
adriamycin resistant P388 M3P2PGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NXq4UGlsUUN3MDC9JFAvODNizszN MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF3NEWwOUc,OTdzNUS1NFU9N2F-
LT12 NIS0UHdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3y5dFQ5KGh? MlzQTWM2OCB;IECuNFA3KM7:TR?= NEXY[WM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
SKOV3 M1nhUGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MXS0PEBp NEX3[JVKSzVyIE2gNE4xOSEQvF2= NUnWNpBmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
NCI-H460 MXPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NIPO[nE1QCCq MmrmTWM2OCB;IECuNFEh|ryP NEHSPIo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
SF268 Mnq5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NXjnVJBqPDhiaB?= M2n1OmlEPTBiPTCwMlAyKM7:TR?= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
RKO NUnoWo5JSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M1rWeVQ5KGh? MmLSTWM2OCB;IECuNFEh|ryP NUXJN5dvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
KB/HeLa MkDMRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MVi0PEBp MWnJR|UxKD1iMD6wNUDPxE1? NVvrN|R[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
P388 NH7HO5FCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Moj6OFghcA>? M2PyR2lEPTBiPTCwMlA1KM7:TR?= NV72cVh[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
L1210 NWi5UohqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NF3lSXg1QCCq MnXFTWM2OCB;IECuNFYh|ryP NH\WWWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
LT12 MDR M2XIfmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NH\CbZk1QCCq NGHxXXRKSzVyIE2gNE41KM7:TR?= MlTGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
A2780 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NGHJ[JFKSzVyIE2gNE4xODFizszN M1LSeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
A2780-1A9 NWXsdFR1S3m2b4TvfIlkcXS7IHHzd4F6 NV;Nd444UUN3MDC9JFAvODBzMTFOwG0> NHLTd449[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
A549 MlPHR5l1d3SxeHnjbZR6KGG|c3H5 MoPETWM2OCB;IECuNFA{PiEQvF2= M3XmfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
1A9PTX22 MY\DfZRwfG:6aXPpeJkh[XO|YYm= MXfJR|UxKD1iMD6wNVkh|ryP M1nIfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
1A9PTX10 M3u2[mN6fG:2b4jpZ4l1gSCjc4PhfS=> M2DMUGlEPTBiPTCwMlA{KM7:TR?= NGDMfIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
A2780AD NYnYeZhjS3m2b4TvfIlkcXS7IHHzd4F6 M2nYRWlEPTBiPTCwMlkh|ryP MmTYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{ME[xN|koRjF5MkC2NVM6RC:jPh?=
KB MknQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M3fx[WlEPTBiPTCwMlAxOjR3IN88US=> MmfSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
COLO205 NEjlSVlEgXSxdH;4bYNqfHliYYPzZZk> NWr6bldOUUN3MDC9JFAvODB|MzFOwG0> Mn;VQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
KB8.5 M{\kc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M4T0eWlEPTBiPTCwMlAzPiEQvF2= MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJ{OEi3N{c,OTd{Mki4O|M9N2F-
KBV1 NXXONppKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXrJR|UxKD1iMj6wNVMh|ryP NYfhW4lsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNlg5PzNpPkG3NlI5QDd|PD;hQi=>
A2780 M4TNZmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mo\4TWM2OCB;IECuNFAxPyEQvF2= NGS1O2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KzPVU6Pyd-MUeyN|k2QTd:L3G+
2780AD M1m5NGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVHJR|UxKD1iMD61N|Uh|ryP NEj3bFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KzPVU6Pyd-MUeyN|k2QTd:L3G+
1A9 MYjDfZRwfG:6aXPpeJkh[XO|YYm= MlT2SWQ2OCB;IECuNFAyKM7:TR?= NITX[2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
MCF7 MnrPR5l1d3SxeHnjbZR6KGG|c3H5 NHmwN|dGTDVyIE2gNE4xODFzIN88US=> MmrTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
DU145 NWLIU2xYS3m2b4TvfIlkcXS7IHHzd4F6 NYj5Zm9HTUR3MDC9JFAvODBzMzFOwG0> MojoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
KB MVHDfZRwfG:6aXPpeJkh[XO|YYm= MnnaSWQ2OCB;IECuNFAyQCEQvF2= M1rMeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
A549 NYXK[npKS3m2b4TvfIlkcXS7IHHzd4F6 NFXnfXhGTDVyIE2gNE4xODJ|IN88US=> M1XtW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
LNCAP NEfXVnREgXSxdH;4bYNqfHliYYPzZZk> MlPSSWQ2OCB;IECuNFAzPiEQvF2= NHiyfXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
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KBVIN MV;DfZRwfG:6aXPpeJkh[XO|YYm= M{\3[mVFPTBiPTCwMlMyOSEQvF2= M2TQ[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
A2780 MoPnR5l1d3SxeHnjbZR6KGG|c3H5 MWLJR|UxKD1iMD6wNFE3KM7:TR?= NVnYOFh5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezPVU1PjVpPkG3N|k2PDZ3PD;hQi=>
A2780/AD NWD1dJNMS3m2b4TvfIlkcXS7IHHzd4F6 MUTJR|UxKD1iMD65NkDPxE1? NV;KTVlyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezPVU1PjVpPkG3N|k2PDZ3PD;hQi=>
KB NHrDWXFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MVTJR|UxKD1iMD6wNFI1PSEQvF2= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzNkWyOEc,OTd2MU[1NlQ9N2F-
COLO205 NIrQ[phEgXSxdH;4bYNqfHliYYPzZZk> NEOxUY9KSzVyIE2gNE4xODN|IN88US=> NHXhTIY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxOlUzPCd-MUe0NVY2OjR:L3G+
KB8.5 NW\wd5FtSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NFzvWFFKSzVyIE2gNE4xOjZizszN MlznQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MU[1NlQoRjF5NEG2OVI1RC:jPh?=
KBV1 NUPENoE5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MWjJR|UxKD1iMj6wNVMh|ryP NE\6UIM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxOlUzPCd-MUe0NVY2OjR:L3G+
neural precursor NUW4UJl3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M4DyTGVEPTBiPTCwMlAyKM7:TR?= M3faW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG3OlMyLz5zN{SxO|Y{OTxxYU6=
OVCAR-3 MX3DfZRwfG:6aXPpeJkh[XO|YYm= M3;NSmlEPTBiPTCwMlAxODJizszN M1q4eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
MDA-MB-231 MWHDfZRwfG:6aXPpeJkh[XO|YYm= MVTJR|UxKD1iMD6wNFQ2KM7:TR?= NFjqRlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
MCF7 M{HLNmN6fG:2b4jpZ4l1gSCjc4PhfS=> MlvDTWM2OCB;IECuNFA1QSEQvF2= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
NCI-H1299 M3PtXmN6fG:2b4jpZ4l1gSCjc4PhfS=> NGPxfYc6PiCq MX\JR|UxKD1iMD6wNVUh|ryP NYrX[25wRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
A2780 M4TG[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NF71PJBKSzVyIE2gNE4xOjVizszN NULqcGtXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
PC3 MUDDfZRwfG:6aXPpeJkh[XO|YYm= MmjLTWM2OCB;IECuNFc4KM7:TR?= NYDu[GlERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
LoVo NXnBTJprS3m2b4TvfIlkcXS7IHHzd4F6 NXTINW9vUUN3MDC9JFAvODlizszN MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
L2987 NVnZXG1xS3m2b4TvfIlkcXS7IHHzd4F6 NFK3TmlKSzVyIE2gNE4zKM7:TR?= MnWwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
cells M1zVemN6fG:2b4jpZ4l1gSCjc4PhfS=> MlfJTWM2OCB;IECuNFA2QSEQvF2= NFr2W|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0NlU4Pyd-MUe0OFI2Pzd:L3G+
cells MYjDfZRwfG:6aXPpeJkh[XO|YYm= M4L3O2lEPTBiPTCwMlAyKM7:TR?= MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR6NUKwO{c,OTd2OEWyNFc9N2F-
A2780 MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MU\JR|UxKD1iMD6wNFI5KM7:TR?= MoLBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUC4O|goRjF5NEmwPFc5RC:jPh?=
VA13 NFz5TFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGG4UpdKSzVyIE2gNE4xODVizszN NVvSOVdWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
WI38 MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV7nUIFIUUN3MDC9JFAvODRizszN NYr4[Xg1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
2780AD MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEXzV5VKSzVyIE2gNE4yQDNizszN MlfxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUC4O|goRjF5NEmwPFc5RC:jPh?=
HepG2 M2PlbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmjhTWM2OCB;IEiuNUDPxE1? NVPx[GZvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
HT29 NF7pR2hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUXKenI5PDhiaB?= MnjiS2k2OCB;IECuNFE2KM7:TR?= MlXOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
M21 NGKyNYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV:0PEBp Ml;JS2k2OCB;IECuNFM4KM7:TR?= MmnXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
MCF7 NWr1XJBuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXmwSGJqPDhiaB?= NXvreHBlT0l3MDC9JFAvODV2IN88US=> M4jjZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEm4PVYxLz5zN{S5PFk3ODxxYU6=
1A9 MljJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PvSFczKGh? NX3NUW1qT0l3MDC9JFAvODByN{Gg{txO M4rwTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUSyOVczLz5zN{W0NlU4OjxxYU6=
1A9/Ptx22 NVm0[ItmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mm\FO|IhcA>? Ml\4S2k2OCB;IECuNFUyKM7:TR?= MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV2MkW3Nkc,OTd3NEK1O|I9N2F-
1A9/Ptx10 MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4fLPFczKGh? Ml;PS2k2OCB;IECuNFY1KM7:TR?= NI\PPFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W0NlU4Oid-MUe1OFI2PzJ:L3G+
cells expressing MRP1 MkPvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlzzTWM2OCB;IECuNFAzPSEQvF2= MmLhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkexNlEoRjF5NU[3NVIyRC:jPh?=
cells expressing Pgp/MRP1 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NETJUnJKSzVyIE2gNk44KM7:TR?= NEK3TlU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W2O|EzOSd-MUe1OlcyOjF:L3G+
VA13 NYjVTppuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXjJR|UxKD1iNTFOwG0> NHO0bJg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W5OVE{PCd-MUe1PVUyOzR:L3G+
MCF7 M3SzZWZ2dmO2aX;uJIF{e2G7 NWfiNI5zUUN3MDC9JFAvODBzODFOwG0> NXnZclF7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFE4OzlpPkG3OlAyPzN7PD;hQi=>
adriamycin-resistant MCF7 NGHQNFRHfW6ldHnvckBie3OjeR?= MUXJR|UxKD1iOD6yJO69VQ>? Mnv2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4MEG3N|koRjF5NkCxO|M6RC:jPh?=
RPMI8226 MY\DfZRwfG:6aXPpeJkh[XO|YYm= NYj1N4NFT0l3MDC9JFAvODB{IN88US=> NH\xTVY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
HT29 M4fNOWN6fG:2b4jpZ4l1gSCjc4PhfS=> NGn5RmtIUTVyIE2gNE4xODJizszN NXf0XGVLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
COLO205 M{HreWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3\GWWdKPTBiPTCwMlAxOyEQvF2= MkToQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HCC2998 M3Tpe2N6fG:2b4jpZ4l1gSCjc4PhfS=> NHL0TnVIUTVyIE2gNE4xODNizszN M322c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
HS578T NHXZS4dEgXSxdH;4bYNqfHliYYPzZZk> MWXHTVUxKD1iMD6wNFMh|ryP NEjmS2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
PC3 NX22WGN2S3m2b4TvfIlkcXS7IHHzd4F6 NWj4ZYo6T0l3MDC9JFAvODB2IN88US=> NX\zfo02RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
SNB75 NFfwSoJEgXSxdH;4bYNqfHliYYPzZZk> NXrR[2tiT0l3MDC9JFAvODB2IN88US=> NEjC[mg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
A549 NFnWfVJEgXSxdH;4bYNqfHliYYPzZZk> M2\kSGdKPTBiPTCwMlAxPCEQvF2= M1HIWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
KM12 NHXUc|NEgXSxdH;4bYNqfHliYYPzZZk> MWfHTVUxKD1iMD6wNFQh|ryP MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
DU145 MmryR5l1d3SxeHnjbZR6KGG|c3H5 Mk\vS2k2OCB;IECuNFA2KM7:TR?= M12xT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
SK-OV3 NIP2dYREgXSxdH;4bYNqfHliYYPzZZk> Ml35S2k2OCB;IECuNFA5KM7:TR?= MmfDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
NCI-H322M NXrKfYhMS3m2b4TvfIlkcXS7IHHzd4F6 NF;yUm9IUTVyIE2gNE4xOTNizszN NG\6NXQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
UACC257 MoW2R5l1d3SxeHnjbZR6KGG|c3H5 NFz3cmpIUTVyIE2gNE4xPCEQvF2= NX7HZ4pURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
HCT15 MVTDfZRwfG:6aXPpeJkh[XO|YYm= NUjudYxXT0l3MDC9JFAvOTV6IN88US=> MlS2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
ACHN NUS1VZVxS3m2b4TvfIlkcXS7IHHzd4F6 NYixTnI5T0l3MDC9JFAvOzl6IN88US=> M3XaU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
HeLa M3LCZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MV3JR|UxKD1iMD6wNFU3KM7:TR?= MmDHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd5NkSxOFgoRjF5N{[0NVQ5RC:jPh?=
MCF7 MmXjR5l1d3SxeHnjbZR6KGG|c3H5 M4\jTmlEPTBiPTCwMlAyOjRizszN NHLESIM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{e2OFE1QCd-MUe3OlQyPDh:L3G+
A549 M{HNV2N6fG:2b4jpZ4l1gSCjc4PhfS=> M{P2c2lEPTBiPTCwMlAyOjZizszN MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzd4NEG0PEc,OTd5NkSxOFg9N2F-
HGC27 NHv2U2FEgXSxdH;4bYNqfHliYYPzZZk> NHf0RXJKSzVyIE2gNE44Pzd6IN88US=> NWrycXZxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe3OlQyPDhpPkG3O|Y1OTR6PD;hQi=>
HL60 NYDOPVdKS3m2b4TvfIlkcXS7IHHzd4F6 MXS3NkBp MYHJR|UxKD1iMD65N{DPxE1? M3rSZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
P388 M{LmdGN6fG:2b4jpZ4l1gSCjc4PhfS=> NF7U[2s4OiCq MYrJR|UxKD1iMD65N{DPxE1? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzh7NkixOkc,OTd6OU[4NVY9N2F-
BEL-7402 NYiwPYNXS3m2b4TvfIlkcXS7IHHzd4F6 NUnrN3R1OjRiaB?= MYfJR|UxKD1iMD65N{DPxE1? Mke5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd6OU[4NVYoRjF5OEm2PFE3RC:jPh?=
A459 M{PC[GN6fG:2b4jpZ4l1gSCjc4PhfS=> MnywNlQhcA>? MXjJR|UxKD1iMD65N{DPxE1? NY\yb49JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe4PVY5OTZpPkG3PFk3QDF4PD;hQi=>
HeLa NI\RUnBEgXSxdH;4bYNqfHliYYPzZZk> MUDJR|UxKD1iMD6wNkDPxE1? Mn;aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUGwNVcoRjF5OUGxNFE4RC:jPh?=
HepG2 MkHRR5l1d3SxeHnjbZR6KGG|c3H5 MXXJR|UxKD1iMD64NkDPxE1? NFLLe2Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxNVAyPyd-MUe5NVExOTd:L3G+
BGC823 NGD2d5hEgXSxdH;4bYNqfHliYYPzZZk> NGO0XnpKSzVyIE2gNU4yPSEQvF2= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzMUCxO{c,OTd7MUGwNVc9N2F-
Aro MoPOR5l1d3SxeHnjbZR6KGG|c3H5 MXO3NkBp NUXIRnFHUUN3MDC9JFAvODByMjFOwG0> MoT2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
PT45 NI\XV4hEgXSxdH;4bYNqfHliYYPzZZk> MoLsO|IhcA>? MX3JR|UxKD1iMD6wNFUh|ryP NFy3NmI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
A549 NVjVOoljS3m2b4TvfIlkcXS7IHHzd4F6 NXvZR5lxPzJiaB?= M374XGlEPTBiPTCwMlAxPiEQvF2= NX7lcGZ2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
MCF7 M{Tt[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYH3NGhZPzJiaB?= NYnqOYdCUUN3MDC9JFAvODB5IN88US=> NVPkWFlYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
HeLa M4HZcWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2exbFczKGh? MYrJR|UxKD1iMD6wNFgh|ryP NYHJUmtKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
Ovcar3 MlPuR5l1d3SxeHnjbZR6KGG|c3H5 NUjwdYtLPzJiaB?= NUnHNmw1UUN3MDC9JFAvODFizszN NF7WfFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
HT29 Mof2R5l1d3SxeHnjbZR6KGG|c3H5 M2rrXVczKGh? NVnDd5JtUUN3MDC9JFAvODVizszN NVnocGxwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
A549T12 NFzrRllEgXSxdH;4bYNqfHliYYPzZZk> M{KzT|czKGh? MWrJR|UxKD1iMD6wOkDPxE1? NXj6dZAzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
H295R M4HS[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYi3NkBp MYnJR|UxKD1iMD6wPEDPxE1? M2m1PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
A549T24 MX;DfZRwfG:6aXPpeJkh[XO|YYm= NYLD[GdbPzJiaB?= MVPJR|UxKD1iMD6xNFIh|ryP MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
OE33 MnTvR5l1d3SxeHnjbZR6KGG|c3H5 MmjjO|IhcA>? NWHkWXJtUUN3MDC9JFAvOiEQvF2= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
HepG2 NEfVV3VEgXSxdH;4bYNqfHliYYPzZZk> NEDmS|k4OiCq MnzoTWM2OCB;IECuN{DPxE1? NF73U289[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
OE19 NXPuXnMyS3m2b4TvfIlkcXS7IHHzd4F6 MXO3NkBp NXr3TWV1UUN3MDC9JFAvPCEQvF2= MoOyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
L12 NVnNSlduSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M2\0flQ5KGh? Mnz5TWM2OCB;IECuNFA3KM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
NCI-H460 M3fpWWN6fG:2b4jpZ4l1gSCjc4PhfS=> NEfSNJE1QCCq NF7IemFKSzVyIE2gNE4xOSEQvF2= MmruQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
SKOV3 NF\hbmtEgXSxdH;4bYNqfHliYYPzZZk> MnvDOFghcA>? MW\JR|UxKD1iMD6wNUDPxE1? MkLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
SF268 M2LtZ2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3TpcVQ5KGh? MXfJR|UxKD1iMD6wNUDPxE1? NWrqeppxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5O|M{PjFpPkG3PVc{OzZzPD;hQi=>
RKO NFL1cFJEgXSxdH;4bYNqfHliYYPzZZk> Mki4OFghcA>? NFXybmFKSzVyIE2gNE4xOSEQvF2= NYrZdIo5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5O|M{PjFpPkG3PVc{OzZzPD;hQi=>
KB/HeLa NWP2Znp2S3m2b4TvfIlkcXS7IHHzd4F6 MnPoOFghcA>? NEjYUXNKSzVyIE2gNE4xOSEQvF2= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
P388 MWXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MY[0PEBp NFr5fpZKSzVyIE2gNE4xPCEQvF2= NED2Z2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis M4GyR2NmdGxiY4njcIUh[XK{ZYP0JIF{e2G7 MnOySWM2OCB;IECuNFQ6KM7:TR?= M1TSTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUezN|YyLz5zN{m3N|M3OTxxYU6=
L1210 NHTjfndCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHfa[nM1QCCq NFnM[HZKSzVyIE2gNE4xPiEQvF2= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
cells after 48 hrs by XTT assay MkfDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MoXxTWM2OCB;IECuOEDPxE1? MlzyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
A2780 NInEb4dEgXSxdH;4bYNqfHliYYPzZZk> NYPzbpVkUUN3MDC9JFAvODB4MzFOwG0> MmHNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
BGC823 NIfke|FEgXSxdH;4bYNqfHliYYPzZZk> M{PO[mlEPTBiPTCwMlAxPyEQvF2= NF\o[o09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
A549 NEPGS3VEgXSxdH;4bYNqfHliYYPzZZk> MlPFTWM2OCB;IECuNFE6KM7:TR?= NHPSU4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
HCT8 NYe0d25YS3m2b4TvfIlkcXS7IHHzd4F6 MU\JR|UxKD1iMD6wN|ch|ryP M{\vPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MECxNFg4Lz5zOECwNVA5PzxxYU6=
Bel7402 NH\1[VVEgXSxdH;4bYNqfHliYYPzZZk> NFHjNGtKSzVyIE2gNE4yKM7:TR?= M3XQdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MECxNFg4Lz5zOECwNVA5PzxxYU6=
cells by alamar blue assay MkPzSpVv[3Srb36gZZN{[Xl? MoTVTWM2OCB;IECuNFQh|ryP NF;T[FQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEC3NFk3PSd-MUiwO|A6PjV:L3G+
PANC1 MnHtR5l1d3SxeHnjbZR6KGG|c3H5 NED6eYc4OiCq MVfJR|UxKD1iMD6wNFch|ryP MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDB6MUK1O{c,OThyOEGyOVc9N2F-
DLD1 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MUK3NkBp MU\JR|UxKD1iMD6wNVEh|ryP M3jyfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MEixNlU4Lz5zOEC4NVI2PzxxYU6=
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NCI/ADR NVnw[IF4S3m2b4TvfIlkcXS7IHHzd4F6 NYLqUHpPPzJiaB?= M4\ydGlEPTBiPTCxJO69VQ>? MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDB6MUK1O{c,OThyOEGyOVc9N2F-
SK-BR3 MlmyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NXniepNtQTZiaB?= MoDES2k2OCB;IE[uNUDPxE1? MofKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThzNkSyNFUoRjF6MU[0NlA2RC:jPh?=
A2780 MmXVRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M3O2elk3KGh? MWrJR|UxKD1iMD6wNlM1KM7:TR?= NYnPbYhURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUixO|cxOTRpPkG4NVc4ODF2PD;hQi=>
SNU398 MXnBdI9xfG:|aYOgZZN{[Xl? MkXXNlQhcA>? NFXKTIJGSzVyIE2gNE4xOTFizszN NEj5N4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEG5O|YyPCd-MUixPVc3OTR:L3G+
HCT116 NGDOe3JCeG:ydH;zbZMh[XO|YYm= MkDkNlQhcA>? MnrYSWM2OCB;IECuNFI1KM7:TR?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
T47D NVP5N2hOSXCxcITvd4l{KGG|c3H5 NX34bmE5OjRiaB?= M3LMTmVEPTBiPTCwMlA{PiEQvF2= MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
SJSA1 NX7UfXI1S3m2b4TvfIlkcXS7IHHzd4F6 M{fmfFYhcA>? M2XvNmlEPTBiPTCwMlAxOzJizszN MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDJ2M{[5Okc,OTh{NEO2PVY9N2F-
P388 MXnDfZRwfG:6aXPpeJkh[XO|YYm= M1nrSFczKGh? MYPJR|UxKD1iMD65N{DPxE1? NGfqcIE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEK4NVk2Oid-MUiyPFE6PTJ:L3G+
HL60 NXWzUXpQS3m2b4TvfIlkcXS7IHHzd4F6 NX;PellZPzJiaB?= NHj0SGZKSzVyIE2gNE46OyEQvF2= M2\RU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkixPVUzLz5zOEK4NVk2OjxxYU6=
Bel7402 NWToUZR1S3m2b4TvfIlkcXS7IHHzd4F6 MWSyOEBp NVjSb|dQUUN3MDC9JFAvQTNizszN NFPhR3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEK4NVk2Oid-MUiyPFE6PTJ:L3G+
A549 NXGxRWhrS3m2b4TvfIlkcXS7IHHzd4F6 MlTUNlQhcA>? NWDofFhCUUN3MDC9JFAvQTNizszN M2CxelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkixPVUzLz5zOEK4NVk2OjxxYU6=
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KBV20C M{D5bmN6fG:2b4jpZ4l1gSCjc4PhfS=> NF3KXoE1QCCq NIrZPZlKSzVyIE2gNU41PCEQvF2= NWrTNG16RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiyPVU1QTBpPkG4Nlk2PDlyPD;hQi=>
DU145 MYHDfZRwfG:6aXPpeJkh[XO|YYm= NIPEcng4OiCq MkXtTWM2OCB;IECuNFA2KM7:TR?= M3;OTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
HL60 NX\sVogxS3m2b4TvfIlkcXS7IHHzd4F6 NV7uc2h{PzJiaB?= MXHJR|UxKD1iMD6wNFUh|ryP NHv6Rok9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
MDA435 NELLW|lEgXSxdH;4bYNqfHliYYPzZZk> NV;vbZl[PzJiaB?= M4DtZmlEPTBiPTCwMlAxPSEQvF2= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNyOEW2Okc,OTh|MEi1OlY9N2F-
MESSA NILZToZEgXSxdH;4bYNqfHliYYPzZZk> MoDaO|IhcA>? M{nzPGlEPTBiPTCwMlAxPSEQvF2= MmT4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEi1OlYoRjF6M{C4OVY3RC:jPh?=
P388 NFn1ZXdEgXSxdH;4bYNqfHliYYPzZZk> NYPhcG9HPzJiaB?= NHvJOIFKSzVyIE2gNE4xOSEQvF2= NX7R[Y9kRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFg2PjZpPkG4N|A5PTZ4PD;hQi=>
HL60/TX1000 NHOwcJhEgXSxdH;4bYNqfHliYYPzZZk> NUXB[Jh7PzJiaB?= NF3MbXVKSzVyIE2gOUDPxE1? NIm1eok9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
MESSA/DX5 NVLiVZpOS3m2b4TvfIlkcXS7IHHzd4F6 MUi3NkBp NWi1WIs6UUN3MDC9JFUh|ryP NH7rXYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
K562 NVHsUnZLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVfNWpczPzJiaB?= MYfJR|UxKD1iMD6wNFA3KM7:TR?= NVHqOHM1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNVM{ODdpPkG4N|E{OzB5PD;hQi=>
KB3-1 MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWDPRppGPzJiaB?= NFrSd2tKSzVyIE2gNE4xODJizszN NGn4Ros9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
HepG2 MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI\Ufpk4OiCq MU\JR|UxKD1iMD6wNFch|ryP NH:5SGw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
KB V1 NUC1Z4RQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWG3NkBp MmDhTWM2OCB;IEig{txO MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNzM{OwO{c,OTh|MUOzNFc9N2F-
A549 MkG4R5l1d3SxeHnjbZR6KGG|c3H5 MVWzJIRigXN? M3XDZ2lEPTBiPTCwMlAxPyEQvF2= NGDySXA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
MCF7 NI[xUY5EgXSxdH;4bYNqfHliYYPzZZk> NUDWT2FMOyCmYYnz NFTqXW5KSzVyIE2gNE4xOTF5IN88US=> MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDRzOUG1OEc,OTh2MUmxOVQ9N2F-
HepG2 M3TES2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXXRWYd5OyCmYYnz M4r1T2lEPTBiPTCwMlA1PjhizszN NFntcnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
MDA-MB-231 NV;0e284S3m2b4TvfIlkcXS7IHHzd4F6 NHvjdWY{KGSjeYO= MV;JR|UxKD1iMD6wO|A{KM7:TR?= NGPzXZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
Hep3B MnLSR5l1d3SxeHnjbZR6KGG|c3H5 MWOzJIRigXN? NVH3dXYyUUN3MDC9JFAvOTNizszN Ml:3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2MUmxOVQoRjF6NEG5NVU1RC:jPh?=
CCRF-CEM NXTQVXZMS3m2b4TvfIlkcXS7IHHzd4F6 M4K4c|czKGh? NWfFSXQ2UUN3MDC9JFAvODBzMke0JO69VQ>? NHqyVFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES1NFQ2Pid-MUi0OVA1PTZ:L3G+
HCT116 MXnDfZRwfG:6aXPpeJkh[XO|YYm= MXe3NkBp MonrTWM2OCB;IECuNFAyOyEQvF2= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR3MES1Okc,OTh2NUC0OVY9N2F-
MX1 M4TDUGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUTrXGFZPzJiaB?= MmHtTWM2OCB;IECuNFM2KM7:TR?= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR3MES1Okc,OTh2NUC0OVY9N2F-
HeLa M1LXc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NVn2c3VWPDhiaB?= M3;4TWlEPTBiPTCwMlAxOTVizszN NVr2NYV3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlE6QTdpPkG4OFYyQTl5PD;hQi=>
HT29 NILkV5RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3PUelQ5KGh? MWPJR|UxKD1iMD6wNFE6KM7:TR?= NV6zVG0zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlE6QTdpPkG4OFYyQTl5PD;hQi=>
U2OS MVjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NVrjb29uPDhiaB?= M1SxVmlEPTBiPTCwMlAzPCEQvF2= Ml;6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkG5PVcoRjF6NE[xPVk4RC:jPh?=
A2780 MoHFR5l1d3SxeHnjbZR6KGG|c3H5 MWe3NkBp Mkf5TWM2OCB;IECuNFAyOzhizszN Mo\MQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
MCF7 MoTlR5l1d3SxeHnjbZR6KGG|c3H5 M3jETlczKGh? NXOwNXNxUUN3MDC9JFAvODBzNzFOwG0> MkLoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
LCC6 NXXxdpNqS3m2b4TvfIlkcXS7IHHzd4F6 NVfjTHdDPzJiaB?= MlrCTWM2OCB;IECuNFA{OSEQvF2= NV3xfXRxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlU5PDZpPkG4OFY2QDR4PD;hQi=>
1A9PTX22 NXzmRWdJS3m2b4TvfIlkcXS7IHHzd4F6 Mlj1O|IhcA>? NYKw[4RUUUN3MDC9JFAvOTZyNzFOwG0> Mmi4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
NCI/ADR NVTRb3FvS3m2b4TvfIlkcXS7IHHzd4F6 NEDPb4g4OiCq NUfWN2k{UUN3MDC9JFAvOyEQvF2= M4HTRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[1PFQ3Lz5zOES2OVg1PjxxYU6=
1A9PTX10 MXnDfZRwfG:6aXPpeJkh[XO|YYm= MYW3NkBp