Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用Selleck该产品发表文献18篇:

客户使用该产品的6个实验数据:

  • Relative NPY and IL6 expression in Myc-CaP cells treated with NE or forskolin for 6 hours, or treated with the β2AR blocker ICI118551 2 hours before NE in the presence of ICI118551 for 6 hours (n ¼ 4)

    Clin Cancer Res, 2018, doi:10.1158/1078-0432.CCR-18-2912. Forskolin purchased from Selleck.

    Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

  • T24 cells were treated with IFN-α (1 × 104 U/mL), TPL2i (2 μM), PD98059 (40 μM), or forskolin (50 μM) for 24 h. The expression levels of COX-2, CREB, and p-CREB were analyzed by western blotting. The β-tubulin was used as the loading control.

    J Exp Clin Cancer Res, 2019, 37(1):288. Forskolin purchased from Selleck.

    Western blot analysis shows pERK levels after 8 hours treatment with forskolin. AC activation with 10 μmol/L forskolin (F).

    Mol Cancer Res, 2017, 15(12):1792-1802. Forskolin purchased from Selleck.

  • The pH-dependent regulation of the nucleo-cytoplasmic translocation of YAP and phosphorylation of YAP was regulated by Forskolin and H 89 2HCl, as assessed by western blotting.

    Sci Rep, 2016, 6:26835. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 MYfGeY5kfGmxbjDBd5NigQ>? NEjPenkyOCEQvF2= NXjWR2NuPiCq MXTpcoNz\WG|ZYOgdIhwe3Cqb4L5cIF1cW:wIH;mJI93\XKneIDy[ZN{\WRiS1zIUFMh[XRiU{SzNy=> M3;jdFI3PDN3NEm4
Mo-DCs MX7GeY5kfGmxbjDBd5NigQ>? NFP6UnM2OCEQvF2= NXrVcnV2OjUkgJno MUXwdo9ud3SnczDJUE0zOyCycn;keYN1cW:wIHnuJJRp\SC|dYDldo5ifGGwdDDv[kB7gW2xc3HuJJN1cW23bHH0[YQhVW9vRFPzxsA> NGfG[5kzPjRzMkm0PC=>
RBMECs  MU\GeY5kfGmxbjDBd5NigQ>? MofrOeKh|ryP Ml3tNeKhcA>? NIDLZpJjdG:la4OgeIhmKFKjY{GgbY5i[3SrdnH0bY9vKGmwZIXj[YQh[nliRV3BVE1KUQ>? MXGyOlM2QDB|OR?=
INA-6 MmPER4VtdCCYaXHibYxqfHliQYPzZZk> NFnWcJoxNTFyMDFOwG0> M3:5OFcz6oDLaB?= NH;1NmlqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> MWOyOlMxPjZ{NB?=
OPM-2 NYCySGRHS2WubDDWbYFjcWyrdImgRZN{[Xl? M3HXN|AuOTByIN88US=> MWO3NwKBkWh? M2G2NYlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 MUSyOlMxPjZ{NB?=
U266 M2HEe2NmdGxiVnnhZoltcXS7IFHzd4F6 NUW3TZBGOC1zMECg{txO MXy3NwKBkWh? NFX6UnlqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> NV\mSZFROjZ|ME[2NlQ>
H929 NFrzUWRE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NI\XemkxNTFyMDFOwG0> M2rl[Vcz6oDLaB?= MV7pcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= NY[5d5NOOjZ|ME[2NlQ>
RPMI 8226 MkLOR4VtdCCYaXHibYxqfHliQYPzZZk> NGTLdnIxNTFyMDFOwG0> NHHKSGM4OuLCiXi= MmjnbY5lfWOnczDj[YxtKGSnYYToJIRwe2ViZHXw[Y5l\W62bIm= Ml\5NlY{ODZ4MkS=
MDCK  MVvGeY5kfGmxbjDBd5NigQ>? MoLPNVAhyrWP NHLsb|EzPCCq MX7EUXNQ MV71dJJm\3WuYYTld{B1cGViZYjwdoV{e2mxbjDv[kBVT0ZvzsKxJIFv\CCFVFfGxsA> NFTydVQzPjJyMkO1Ni=>
MDCK  MlKxSpVv[3Srb36gRZN{[Xl? MlHaNVAhyrWP MlzCNlQhcA>? M1fZO2ROW09? M{HPfolvcGmkaYTzJJRp\SCrbnPy[YF{\WRiZYjwdoV{e2mxbjDv[kBHViClYYXz[YQh[nliVFfGMe6zOQ>? M13zXlI3OjB{M{Wy
Spinal cords  NEDmSZBHfW6ldHnvckBCe3OjeR?= MVqxxsDPxE1? M2TmSlMxKG2rbh?= MUjzeIlufWyjdHXzJINCVVBibHX2[Yx{ MXeyOlEzPjl{Nh?=
BeWo  NGnP[WJHfW6ldHnvckBCe3OjeR?= MlH0NlXjiIoQvF2= M4rNfFI1NzR6L{eyJIg> Mo\KcIVi\HNidH:gZY4hcW6lcnXhd4UhcW5idHjlJIV5eHKnc4Ppc44hd2Zib4To[ZIh\nW|aX;uJI1iemuncoO= M3m1V|I3ODV|NUS5
bovine oocytes NWnVPW46TnWwY4Tpc44hSXO|YYm= M4TPUFExOMLizszN M1LlNVEzyqCq NXXYWYVlcW6qaXLpeJMhfGinIHXm[oVkfCCxZjDOVHBCKGGwZD;vdkBPWFCFIITvJJN1cW23bHH0[UBz\XO3bYD0bY9vKG:oIH3lbY9{cXN? NES2VWUzPjB3MU[xNS=>
Caco-2  NF3TOJFHfW6ldHnvckBCe3OjeR?= MmHsNE4yNzFxMUCg{txO NELlZoczOMLibXnu MUnpcoR2[2W|IHGg[I9{\S2mZYDlcoRmdnRiaX7jdoVie2ViaX6gbY51emGlZXzseYxieiClQV3QJIxmfmWucx?= NUf1e|BLOjZyNEmxNFI>
Caco-2  NEX1Z|FHfW6ldHnvckBCe3OjeR?= NELmfVUxNjFxMT:xNEDPxE1? NHzZNIEzPCCq MUDpcoNz\WG|ZYOgUXJROiCycn;0[YlvKGyndnXs NVr0dm5[OjZyNEmxNFI>
AML-12  NF7OWJRHfW6ldHnvckBCe3OjeR?= M{XHXlIxKM7:TR?= MUKzJIg> NXTTTlYxfXC{ZXf1cIF1\XNidHjlJJBpd3OyaH;yfYxifGmxbjDs[ZZmdHNiYYSgWIhzNTRzMTDhcoQhW2W{LUS5Ny=> MWCyOlA1QDl6NR?=
AML-12  MljCSpVv[3Srb36gRZN{[Xl? MknzNlAh|ryP NEfzRmQyNThiaB?= MVjpcoNz\WG|ZYOg[4x2[2:|ZTDwdo9lfWO2aX;u NVTOU5pNOjZyNEi5PFU>
AML-12  NGrTUIdHfW6ldHnvckBCe3OjeR?= NWTvZVdROjBizszN Mn7YN{Bp MoHteZAuemWpdXzheIV{yqCSZ3OxZUzDqFCncHPrMEBidmUEoFe2dIPDqG2UTlGgcIV3\Wy| NHe5V4kzPjB2OEm4OS=>
AML-12  M2OzZmZ2dmO2aX;uJGF{e2G7 NFvnbnUzOCEQvF2= Mn7NN{Bp MlLNbY5lfWOnczD0bIUh\GWyaH;zdIhwenmuYYTpc44hd2ZiQ2LUR|LDqA>? Ml\ZNlYxPDh7OEW=
RBMECs Mm\jSpVv[3Srb36gRZN{[Xl? M4fwe|XDqM7:TR?= NHXmTY4yKGh? NVLWNVdncW6qaXLpeJMhTU2DUD3JTU1qdmS3Y3XkJIlv[WO2aY\heIlwdiCxZjDSZZAyyqB? NX7NWFJbOjZyNES2OlM>
EndoC-βH1 NWPuZ|dqTnWwY4Tpc44hSXO|YYm= M2j1flXDqM7:TR?= MkLCNUBp M4rERpBwfGWwdHnheIV{KGeudXPvd4UucW6mdXPl[EBqdnO3bHnuJJNm[3KndHnvckBqdiC2aHWgdJJme2WwY3Wgc4Yh\2y3Y3;z[S=> NEfIcIUzPjB{OEW2Ni=>
EndoC-βH1 MlTaSpVv[3Srb36gRZN{[Xl? NILsTJU2yqEQvF2= NHvrVWoyKGh? MVvs[YFleyC2bzDhJJN1em:wZzDjRW1RKGmwY4LlZZNm M3;udlI3ODJ6NU[y
SH-SY5Y MniySpVv[3Srb36gRZN{[Xl? MlLpN|Ah|ryP MV:zNEBucW5? MmS5SG1UVw>? M2LLdJNq\26rZnnjZY51dHliaX7jdoVie2W|IITo[UBi[3SrdnH0bY9vKG:oIGDLRS=> Mkf1NlYxOjVzM{e=
PC-3 MX7GeY5kfGmxbjDBd5NigQ>? NYLSOII4PDBiwsXN MmTONkBp MWTEUXNQ NInid2xt\WGmczD0c{BRWDKDIHHjeIl3[XSrb36= Mn\MNlYxOjN6M{[=
PC-3 MXnD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MonvOFAhyrWP MV:yOE81QC95MjDo M{TLVWROW09? M2LqUIRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTD0bY1mKGSncHXu[IVvfGy7 MlO3NlYxOjN6M{[=
SCG NIPid3VHfW6ldHnvckBCe3OjeR?= NIDWN2UzOCEQvF5CpC=> M{nkU2ROW09? NWPGe3h{emW4ZYLzbYJtgSC|dYDwdoV{e2W|IFnLWkB4cXSqIHGgTWM2OCCxZjCyOE41KM7:TR?= NVPnN4NEOjV7NkKxN|I>
HEK-293 NGr6cYpHfW6ldHnvckBCe3OjeR?= MYSzOUDPxE4EoB?= MVPEUXNQ Mk\pbY5lfWOnczDhJINwdnOyaXP1c5V{KOLCnHnuZYN1cX[jdHnvcwKBpSCxZjD0bIUhU3Z{LkGgZ5VzemWwdB?= MlzmNlU6PjJzM{K=
SCG NUHKTIZXTnWwY4Tpc44hSXO|YYm= MV2xNFAh|ryPwrC= NX;B[WVbTE2VTx?= NX\1VodqemWmdXPld{B1cGViZYjjbZRi[mmuaYT5JI9nKFOFRzDu[ZVzd26| NUTmN4h1OjV7NkKxN|I>
PCCL3 MX7GeY5kfGmxbjDBd5NigQ>? NYT2UXpkOTBiwsXN M3jOc|I1KGh? NGL6epVmdmijbnPld{BFfU:6MjDwdo9ud3SncjD0doFve2O{aYD0bY9vKGGldHn2bZR6yqEkgJu= NULnTHBbOjV7NkC5OVY>
3T3-L1 preadipocytes NVK1[JB[TnWwY4Tpc44hSXO|YYm= M{\QWlExKM7:TdMg MVGxNkBp M3rLSYlv\HWlZYOgR3JGSiCyaH;zdIhwenmuYYTpc44h[W6mIFOvSWJR|rJiZYjwdoV{e2mxbh?= NGDlRYUzPTl{OEC1PC=>
H295R  MU\GeY5kfGmxbjDBd5NigQ>? NG\JZ|UyOMLizszN MUi0POKhcA>? NFLDRo5qdmO{ZXHz[ZMhe3Sncn;p[EBu\XSjYn;sbZRmeyCrbjD0bIUh[W6mcn;n[Y4tKG2rbnXyZYxwNSCjbnSg[4x2[2:lb4L0bYNwcWRicHH0bJdigXN? NXzkRottOjV6Nkm1OVY>
PBMC NIPhU4pHfW6ldHnvckBCe3OjeR?= NUP3dphRPTEEoN88US=> MXOyOOKhcMLi MlK4bY5pcWKrdIOgeIhmKGmwY4LlZZNm\CC|ZXPy[ZRqd25ib3[gWG5HKGmwZIXj[YQh[nlidHjlJGRRTQ>? MWSyOVg3PjB5OR?=
GLUTag  M1SzeGZ2dmO2aX;uJGF{e2G7 NVmyc4RsOTEkgJpCuW0> MUGwM|IwPCCq MlrMd5RqdXWuYYTld{BIVFBvMTDz[YNz\XSrb36gZ491emWjdHXkJJdqfGhiSVLNXC=> M2P3[lI2QDN{NkOx
GLUTag  M124e2Z2dmO2aX;uJGF{e2G7 NFznfGoyOOLCidM1US=> MXi0JIg> M{jDc4lv[3KnYYPld{B1cGVicFPSSWIhdGW4ZXzzJJdqfGhidHjlJGlDVVh? M{\yR|I2QDN{NkOx
BAECs NF\2TXFHfW6ldHnvckBCe3OjeR?= NYn2PVQzOjVizszN NHfIdlkzPCCq NX;sbYhv\W6qYX7j[ZMhfGinIHHjeIl3[XSrb36gc4YhWFCDUt8xJIJ6KDVizszNJJJme3[ncnH0do9tNCCWNFjTMEBweiB2LWDBVC=> NWrQT2hXOjV5OUi4NlY>
PC12 M{HnWWZ2dmO2aX;uJGF{e2G7 M4rhNVI2yqEQvF2= NX64RVZKPDhiaB?= NV\selE1[WO2aY\heIV{KGODTWC= MXWyOVc3QTNyNR?=
GH3 MofoSpVv[3Srb36gRZN{[Xl? M1Lw[lHDqM7:TR?= NVPVTG9DPi2q MkPIZZR1\W63YYTld{B1cGViY3;ydoVt[XSrb36gZoV1f2WnbjDQVmwh[W6mIFLtZYwyKGW6cILld5Nqd25? M2HwdFI2PzJ5MEG4
GH3 M1H6NGZ2dmO2aX;uJGF{e2G7 MWCxxsDPxE1? MmTLOk1p MYjpcoR2[2W|IGDSUEBidmRiQn3hcFEtKGK3dDDuc5QhS2yxY3usJI1TVkFiZYjwdoV{e2mxbh?= NXzvVHQ{OjV5MkewNVg>
BeWo M3PjdGZ2dmO2aX;uJGF{e2G7 NYL5ZmE5OTEkgJtOwG3DqA>? NG\I[I44OiCq NYnOcnY1TE2VTx?= NWmwcpBjdWWmaXH0[ZMhSmWZbzDj[YxtKGSrZn\ldoVvfGmjdHnvci=> NIfSOoUzPTdzM{SyOS=>
oocytes MVvGeY5kfGmxbjDBd5NigQ>? M3zlcVUh|ryP NHPlOpQzPCCq MkTOZZR1\W63YYTld{BzcC2rboP1cIlvKGGldHnvckBwdiCxb3P5eIUhT1[ERDDzbYdvcW[rY3HueIx6yqB? NWW3ZnRqOjV5MEe4OVQ>
SC MnOwSpVv[3Srb36gRZN{[Xl? MWOwMlUh|ryP NV\WTm41OjRiaB?= MYjtbY1q[2u|IITo[UBm\m[nY4Sgc4Yh[0GPUDDhcoFtd2e|IH;uJG8yKGGwZDDNRnAh\XiycnXzd4lwdg>? MYqyOVcxPTh5NB?=
SC M1LXVmZ2dmO2aX;uJGF{e2G7 MoTMNE42KM7:TR?= NFvEW3Q4OiCq NGXhbGZqdmO{ZXHz[ZMh[m:2aDDLdo95NTJyIHHu[EBQOSCneIDy[ZN{cW:wIHnuJIF5d25vcnXsZZRm\CCVQ4OgZpV1KG:wbImgT5JwgC1{MNMg MljYNlU4ODV6N{S=
UACC-647  NH3QXG5HfW6ldHnvckBCe3OjeR?= M3z2[GROW09? NHfDcndt\WGmczD0c{BiKHKrc3WgbY4h[0GPUDDs[ZZmdHNiKFXDOVDDqD4EoEKwMlM6yqEQvF2p MkDLNlU4ODNyMkW=
UACC-647  NGXn[5dHfW6ldHnvckBCe3OjeR?= NGXrOlkyOMLizszN MlH1NVUhdWmw NYq5SFk5TE2VTx?= MUfpcohq[mm2czDFVmsheGixc4Doc5J6dGG2aX;u MmnaNlU4ODNyMkW=
UACC-647  NH:2[opHfW6ldHnvckBCe3OjeR?= MmX0NVDDqM7:TR?= M4\JVFE2KG2rbh?= NVnqe2lLTE2VTx?= M2\2VYlv[3KnYYPld{BmTUZ{IIDoc5NxcG:{eXzheIlwdiCuZY\lcJPDqA>? NVXVTFFOOjV5MEOwNlU>
SH-SY5Y  MojaSpVv[3Srb36gRZN{[Xl? MYmxNOKh|ryP M3q5TlHDqGkEoB?= NUm4[lhrcW6lcnXhd4V{KEyXQzDhZ5Rqfmm2eR?= Mn:1NlU2QTd2M{O=
SH-SY5Y  NHm3[ndHfW6ldHnvckBCe3OjeR?= NXnpSlhDOTEEoN88US=> MonPNeKhcMLi NFzBNVFqdmO{ZXHz[ZMhSUeFMTDtVm5CKGyndnXs MVyyOVU6PzR|Mx?=
hADSCs NWHkUI1OTnWwY4Tpc44hSXO|YYm= MX[15qCKyrWP NHnzXIM{OCCvaX6= MoLJbY5kemWjc3XzJINCVVBibHX2[Yx{ NWCzUnJFOjV3OUG5NFg>
HEK293  MmKySpVv[3Srb36gRZN{[Xl? NYTsW5h7PeLCidM1US=> MVWzNEBucW5? MVnpcoNz\WG|ZYOgZ2FOWCCuZY\lcJM> MX6yOVU6OTlyOB?=
3T3-L1 M3XVOmZ2dmO2aX;uJGF{e2G7 MVmyMlUwPSEQvF2= NF71OlMzPCCqwrC= NY\4PINSe2mpbnnmbYNidnSueTDk[YNz\WG|ZYOgRXRIVCCycn;0[YlvKGW6cILld5Nqd25iYYSgZYxtKGSxc3XzJJRme3SnZB?= MlTuNlU2QTB3OUe=
OCI-Ly1  NXrnV5dvTnWwY4Tpc44hSXO|YYm= NX73VmpGPDEEoN88US=> NXXpdZF2OcLiaNMg MmqySG1UVw>? NFzQZ5RqdmS3Y3XzJJRp\SCrbnPy[Y1mdnRib3[gZ2FOWCClb37j[Y51emG2aX;udy=> MnTmNlU2PzZ{MkC=
OCI-Ly18  MoTHSpVv[3Srb36gRZN{[Xl? M4rQbVQxyqEQvF2= NYniT3o2OcLiaNMg M{j3ZWROW09? NVjENZd1cW6mdXPld{B1cGViaX7jdoVu\W62IH;mJINCVVBiY3;uZ4VvfHKjdHnvcpM> MoLwNlU2PzZ{MkC=
BeWo MlnBSpVv[3Srb36gRZN{[Xl? MmXTNlDDqML3TR?= MYC0POKhcA>? NEXYTGhFVVOR MkXNbY5kemWjc3XzJJRp\SCmaX\m[ZJmdnSrYYTpc44hd2ZiQnXXc{Bk\Wyucx?= NXHZV2o5OjV3Nk[3OFA>
BeWo M3rxfmZ2dmO2aX;uJGF{e2G7 MlHyNlDDqML3TR?= MnXPOFjDqGh? NED6b25FVVOR Mmq3bY5kemWjc3XzJJRp\SCjZHjld4lwdiCxZjDUTHAuOSCvb37vZ5l1\XN? M{nwfVI2PTZ4N{Sw
LNCaP  NFz4R|JHfW6ldHnvckBCe3OjeR?= NUixR|dqOTEEoN88US=> MmixNVIhcMLi MVnEUXNQ M2rScolv\HWlZYOgZUBlemGvYYTpZ{BqdmO{ZXHz[UBw\iCFUlXCNUBi[3Srdnn0fS=> NI\FTHQzPTV2OEC5PS=>
ThGCs  NYPSNZQ1TnWwY4Tpc44hSXO|YYm= Mm\QNVDjiIsQvF2= NVW1[W1DPOLCini= NVvIPVhn[XWpbXXueJMhUEmIMVGgcIV3\Wy|IIToZZQhf2W{ZTDzeIlufWyjdHXkJIJ6KEOxQ3yy NF;CV44zPTR|M{CyOy=>
ThGCs  MXXGeY5kfGmxbjDBd5NigQ>? MYSxNQKBks7:TR?= NWTUbYV[POLCini= MkS2bY5kemWjc3XzJGNwS2x{LXnu[JVk\WRiRVTONuKh\2WwZTDlfJBz\XO|aX;u MnnVNlU1OzNyMke=
ThGCs  MY\GeY5kfGmxbjDBd5NigQ>? M{fqWFEx6oDMzszN M3P6UVMhcA>? NWHPVoc3cW6qaXLpeJMhfGinIHXm[oVkfCCxZjDINm8zKG:wIFXEUlIhdVKQQR?= MkPtNlU1OzNyMke=
RBMECs Mom3SpVv[3Srb36gRZN{[Xl? NFnNV3YxNjB3L{CuOU82KM7:TR?= Ml72NE4zPSCq NVOxeldQcW6lcnXhd4V{KGODTWCgZ49v[2WwdILheIlwdg>? MWSyOVQyPjZ3MR?=
RBMECs NX7l[pRRTnWwY4Tpc44hSXO|YYm= M2P3WVXDqM7:TR?= NIPifZoyKGh? M3L4SoJtd2OtczD0bIUh[WO2aY\heIlwdiCxZjDSbI9CN1KRQ1ugbY5lfWOnZDDifUBGVUGSLVnJ M{\COlI2PDF4NkWx
RBMECs MVnGeY5kfGmxbjDBd5NigQ>? MYW1xsDPxE1? MXixJIg> MYDwdoV3\W62czD0bIUhTU2DUD3JTU1qdmS3Y3XkJHRGTVJidnHseYUh\GWlcnXhd4U> NX[4fmJqOjV2MU[2OVE>
RBMECs MUXGeY5kfGmxbjDBd5NigQ>? NF\XfGk2yqEQvF2= NF73OXoyKGh? NEDXZZRxemW4ZX70d{B1cGViaX7jdoVie2ViaX6gTHJRKG[udYigZYNzd3O|IITo[UBDXEJiaX7keYNm\CCkeTCgSW1CWC2LSR?= MknTNlU1OTZ4NUG=
RBMECs M3XFPGZ2dmO2aX;uJGF{e2G7 MlG1OeKh|ryP MkG3NUBp MXXpcohq[mm2czD0bIUh\GWlcnXhd4VlKG:oIHHtc5VvfCCxZjDaU{0yKGmwIF3Gd{BqdmS3Y3XkJIJ6KEWPQWCtTWk> NULGbWxnOjV2MU[2OVE>
RBMECs M1;OV2Z2dmO2aX;uJGF{e2G7 M1Hv[VXDqM7:TR?= MmX1NUBp NXLsO2lpemW4ZYLz[ZMhfGinIHPoZY5o\XNiaX6gXm8uOSCmaYP0doljfXSrb36gd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70 MmTvNlU1OTZ4NUG=
RBMECs NIXiPGdHfW6ldHnvckBCe3OjeR?= MljyOeKh|ryP M1fJeFEhcA>? Mo\CZoxw[2u|IITo[UBGVUGSLVnJMYlv\HWlZXSgZ4hidmenIHnuJG1NSyCyaH;zdIhwenmuYYTpc44> NWLvTZM3OjV2MU[2OVE>
RBMECs NWLOdJMyTnWwY4Tpc44hSXO|YYm= NIH2TnQ2yqEQvF2= NXzGSJNXOSCq M4Xv[IJtd2OtczD0bIUh[WO2aX6gZ5l1d3OtZXzleI9vKHKnYYLyZY5o\W2nboSgd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70xsA> M1OzNFI2PDF4NkWx
Primary bovine chondrocytes MojuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLDXmZjPc7:TR?= Mn\ZOFghcA>? NXnsVXlMemW4ZYLz[ZMhfGinIHnubIljcXSxcomg[YZn\WO2IH;mJINmdGWlb4jpZkBwdiCycn;sbYZmemG2aX;uJIlvKGe{b4f0bEBxdGG2ZTDjbI9v\HKxY4n0[ZM> NXvXOm9pOjV2ME[wNVY>
EM1  Mmq2SpVv[3Srb36gRZN{[Xl? NVyx[XQ3OTYkgJtOwG0> NELScpk1QCCq MY\y[YR2[2W|IITo[UBmgHC{ZYPzbY9vKG:owrDMTWbDqG:{wrDQWGdUOsLiaX9CpGNCVFJvIH;yxsBGWEGFMj3zbYxmdmOnZDDFUVEh[2WubIRCpC=> M2nDc|I2Ozd6Nk[x
BeWo  M{njUmZ2dmO2aX;uJGF{e2G7 NILXZ|EzOMLiwsXN NEG5[VE1QMLiaNMg MlfYSG1UV8Li MoDubY5kemWjc3XzJJRp\SCkZYThMYhETyC{ZXzlZZNm NIDVV5AzPTN4MkK2NC=>
BeWo  M2HBNWZ2dmO2aX;uJGF{e2G7 MnLkNlDDqML3TR?= MoXXOFjDqGkEoB?= NHzZXXpFVVORwrC= M4rFSYRwf26{ZXf1cIF1\XNidHjlJIxmfmWuIH;mJHROTU2IMU[= M4TQdFI2OzZ{Mk[w
BeWo  NEfQVmJHfW6ldHnvckBCe3OjeR?= NVnLT2N3OjEEoNM1US=> M3X2PFQ5yqCqwrC= NFzCPZlFVVORwrC= NVq4eGNq\G:5boLl[5Vt[XSnczD0bIUhdGW4ZXygc4YhT0OPLUG= NE\WNHozPTN4MkK2NC=>
granulosa cells M3juc2Z2dmO2aX;uJGF{e2G7 NXXWUGpSOTBizszN NE\lV2gyOi9{NDDo NHjGTllqdmO{ZXHz[ZMhfGinIHzleoVteyCxZtMgVmdUOsLibWLORS=> MWqyOVM{QTFyNR?=
granulosa cells NIX1Z3BHfW6ldHnvckBCe3OjeR?= NUfxeJhuOTBizszN M4H3flEzNzJ2IHi= MnLsbY5kemWjc3XzJJRp\SCuZY\lcJMhd2ZicnXwc5J1\XJiYXP0bZZqfHliZn;yJJRp\SCub37n[ZN1KG[{YXft[Y51KCkkiKK4OVQwMzF6UlfTNk5NXUNr NX:yO3NXOjV|M{mxNFU>
granulosa cells NYT2VXI3TnWwY4Tpc44hSXO|YYm= NYr6bnU{OTBizszN M16yWFI1KGh? Mni1bY5kemWjc3XzJJRp\SCrboTlcpNqfHlib3[gSG5CN3C{b4TlbY4h[2:vcHzlfC=> MVyyOVM{QTFyNR?=
granulosa cells M1L3TGZ2dmO2aX;uJGF{e2G7 M4ThWFExKM7:TR?= NEn6dnMzPCCq M3zmTolv[3KnYYPld{B1cGVibHX2[Yx{KG:oIGLHV|IheHKxbX;0[ZIh[WO2aY\peJk> MmTFNlU{OzlzMEW=
SK-N-AS  NXzqd4hlS2WubDDWbYFjcWyrdImgRZN{[Xl? NWjqS3QyOTBizszNxsA> NVfWW3BYOjRxNEigbC=> MoPZ[Y5p[W6lZYOgeIlu\S2mZYDlcoRmdnSueTDj[YxtfWyjcjD2bYFjcWyrdIpCpC=> NUHDT246OjV{Nk[wOlM>
SK-N-AS  MXfGeY5kfGmxbjDBd5NigQ>? NXvXVYU6OTBizszNxsA> M1XBbFI1KGh? NUnjWpF2cW6lcnXhd4V{KHSqZTDjRW1RKGyndnXsd:Kh MkC1NlUzPjZyNkO=
SK-N-AS  NIfB[oRHfW6ldHnvckBCe3OjeR?= MmDENVAh|ryPwrC= NH3WZ4IzPCCq Mm\ObY5kemWjc3XzJJRp\SCneIDy[ZN{cW:wIH;mJIN6[2yrbjDENS=> MUiyOVI3PjB4Mx?=
SK-N-AS  M3zWTmZ2dmO2aX;uJGF{e2G7 M2PYblExKM7:TdMg NH\WUWQ{OCCvaX6= MofnbY5lfWOnczDwbI9{eGixconsZZRqd25ib3[g{tIu[2G2ZX7pckApe2W{Nke1LUwheC2JU1uz{tIhMHOnckmpJIFv\CClb37jc41qfGGwdDDobYdp\XJibHX2[Yx{KG:oIHHjeIl3\SxidX7wbI9{eGixconsZZRm\CxizsKtZ4F1\W6rbh?= Mk\NNlUzPjZyNkO=
SK-N-AS  NIn0NZhHfW6ldHnvckBCe3OjeR?= NFPjUWsyOCEQvF5CpC=> NWGzVVRjOTBxM{CvOlAhdWmw NU\qTGZ7cW6lcnXhd4V{KGyndnXsd{Bw\iCyLd8yMYNifGWwaX6gLJNmejZ5NTmgZY5lKGmwZIXj[ZMh[WOldX31cIF1cW:wIH;mJJAu|rJvY3H0[Y5qdiBqc3XyOlc2MSCrbjCodIVzcSmwdXPs[YFzKHKnZ3nvcpM> NFjEPFAzPTJ4NkC2Ny=>
SK-N-SH M3;VNGNmdGxiVnnhZoltcXS7IFHzd4F6 NEDUcI4yOCEQvF5CpC=> NV30XFJtPDhiaB?= M3vSRoVvcGGwY3XzJHNMNU5vU1igcoV2em:kbHHzeI9u[SClZXzsJJZq[WKrbHn0fS=> M1;xPVI2OjZ4ME[z
HEK‐CFTR NYPPV2ZCTnWwY4Tpc44hSXO|YYm= NUGzN|ZiOuLCk{WwxsDPxE1? M3:zd|AuOTJibXnu MXnEUXNQyqB? NVH5b|RycW6mdXPld{BiKGSxc3ZihLBl\XCnbnTlcpQhcW:maXTlJIVn\my3eNMg NGfhNHIzPTJ4M{KwOy=>
L6 MWrGeY5kfGmxbjDBd5NigQ>? M3Sze|QxKML3TR?= NHLxW|IzPCCq MnOwbY5pcWKrdIOgSG1JOS2rbnT1Z4VlKEGtdDDhZ5RqfmG2aX;u MVqyOVI1PzV3MB?=
MIN6  NX7XUIk5TnWwY4Tpc44hSXO|YYm= MXOxNEDPxE4EoB?= MWGzJIg> MYTpcoNz\WG|ZYOgSFMhdVKQQTDlfJBz\XO|aX;u NX3Tc2V6OjV{NEGxNlQ>
ventricular cardiomyocytes  NGThVGZHfW6ldHnvckBCe3OjeR?= MnzMNE4xOS1zMDFOwG0> MoPVbY5kemWjc3XzJEBkSU2SIHHjZ5VufWyjdHnvci=> M3n1bFI2OjB|MUGz
ventricular cardiomyocytes  MnPmSpVv[3Srb36gRZN{[Xl? M3HadlAvODFvMUCg{txO NHju[|lmfm:tZYOgZY4hcW6xdILvdIlkKHKnc4DvcpNmKDF{MNMxNVUmKGGkb4\lJIJie2GuIIfpeIgh[W5iRVO1NOKhd2ZiMj6yJOK2VQ>? MVmyOVIxOzFzMx?=
BeWo  NIi4cFZHfW6ldHnvckBCe3OjeR?= NXf6OGdiOjBiwsXN NFzKdIw1QCCq NFXNOnJFVVORwrC= MlPFbY5lfWOnczDj[YxtKG[3c3nvci=> MU[yOVE5PDR5Nx?=
THP-1  Mo\aSpVv[3Srb36gRZN{[Xl? MXWxM|ExKM7:TR?= NYHVS3lCOsLiaB?= NVTSXo1pTE2VT9Mg NH3KZnB{fXCycnXzd4V{KE2FUD2xJJBzd2S3Y4Tpc47DqA>? MYOyOVE2PDh6Mh?=
Huh-7 NV74SohvTnWwY4Tpc44hSXO|YYm= NYDxT2x3OC1{MDFOwG0> M2HacVIhcMLi Mm\HdoV{fWy2czDpckBiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGNvTYnjJIV5eHKnc4Ppc44h[XRidHjlJJBzd3SnaX6gZY5lKG2UTlGgcIV3\Wy| MWGyOVExQTh|NB?=
C6 MYDGeY5kfGmxbjDBd5NigQ>? MnTXNVAh|ryPwrC= M4HabFIxKG2rbh?= NHWwdJRqdmO{ZXHz[ZMh[0GPUDDhZ4N2dXWuYYTpc44> M{nCbFI2ODZ7NEG3
SW480 MV7GeY5kfGmxbjDBd5NigQ>? NWLCNo9RPDEEoN88US=> MWK0POKhcA>? NVjndJhwTE2VTx?= NIq3Noxi[3SrdnH0[ZMhWFB{QR?= MkHaNlQ6QTd2NUG=
HT-29  Ml\iSpVv[3Srb36gRZN{[Xl? NEGxcHY1OMLizszN MVi0POKhcA>? NX3SNo9nTE2VTx?= M2rtfoFkfGm4YYTld{BRWDKD NUHlVox5OjR7OUe0OVE>
SW480 NIPtZ5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWCxcFAzPDEEoN88US=> MljSNE04OiCq MoGzSG1UVw>? Ml3KbY5pcWKrdIOgZ4VtdCCpcn;3eIghfGmvZTDk[ZBmdmSnboTsfS=> MUOyOFk6PzR3MR?=
HT-29  MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXu0NOKh|ryP NIfnSlkxNTd{IHi= NIj4WFZFVVOR NF;qS5FqdmirYnn0d{Bk\WyuIHfyc5d1cCC2aX3lJIRmeGWwZHXueIx6 MonENlQ6QTd2NUG=
SW480 M2jvfGZ2dmO2aX;uJGF{e2G7 M{XB[lQxyqEQvF2= NFr2[VU4KGR? MlPGSG1UVw>? M4PpcZJm\HWlZYOgZ49td26xc4Do[ZJmKG[xcn3heIlwdiClYYDhZoltcXS7wrC= NGnNNJQzPDl7N{S1NS=>
HT-29  MXPGeY5kfGmxbjDBd5NigQ>? NXG2e2xWPDEEoN88US=> NIr4e3c4KGR? M13wVWROW09? MXry[YR2[2W|IHPvcI9vd3OyaHXy[UBnd3KvYYTpc44h[2GyYXLpcIl1gcLi NUDtSJc6OjR7OUe0OVE>
SW480 NFnmW4VCeG:ydH;zbZMhSXO|YYm= NWHwS|ZZPDEEoN88US=> NHjlU2U1QMLiaB?= M{\MRmROW09? NV3ocVZCcW6mdXPld{BidiCjY4TpeoF1cW:wIH;mJINie3Cjc3WgN{84 NH7uU4kzPDl7N{S1NS=>
HT-29  MXnBdI9xfG:|aYOgRZN{[Xl? NYXqSJBoPDEEoN88US=> MXO0POKhcA>? M{HIcWROW09? M3L2NYlv\HWlZYOgZY4h[WO2aY\heIlwdiCxZjDjZZNx[XOnIEOvOy=> MXKyOFk6PzR3MR?=
SW480 NEjBOllCeG:ydH;zbZMhSXO|YYm= M2TTSlQxyqEQvF2= MVm0POKhcA>? MmTLSG1UVw>? M4XqOolv\HWlZYOgZ4hidmenczDpckB1cGVicHjvd5Bpd3K7bHH0bY9vKHO2YYT1d{Bw\iCSUELBJJRiemendIO= NVfnPGZtOjR7OUe0OVE>
HT-29  M3r2PGFxd3C2b4Ppd{BCe3OjeR?= NV7jNGpkPDEEoN88US=> NV\sVYYxPDkEoHi= NXHtUIE{TE2VTx?= M1TOfolv\HWlZYOgZ4hidmenczDpckB1cGVicHjvd5Bpd3K7bHH0bY9vKHO2YYT1d{Bw\iCSUELBJJRiemendIO= Mn\WNlQ6QTd2NUG=

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
in solvent
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null Not Applicable
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null Not Applicable

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID