Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 NV;FbG1kTnWwY4Tpc44hSXO|YYm= MoPrNVAh|ryP NEfuO5o3KGh? NGTZV3pqdmO{ZXHz[ZMheGixc4Doc5J6dGG2aX;uJI9nKG:4ZYLlfJBz\XO|ZXSgT2xJVDNiYYSgV|Q{Ow>? NIe0NmYzPjR|NUS5PC=>
Mo-DCs MYHGeY5kfGmxbjDBd5NigQ>? NWTE[IF2PTBizszN NYLNe4Z[OjUkgJno NFXJTHJxem:vb4Tld{BKVC1{MzDwdo9lfWO2aX;uJIlvKHSqZTDzeZBmem6jdHHueEBw\iC8eX3vd4FvKHO2aX31cIF1\WRiTX:tSGN{yqB? NXPYPVNLOjZ2MUK5OFg>
RBMECs  MWXGeY5kfGmxbjDBd5NigQ>? MVm1xsDPxE1? MoT1NeKhcA>? MVnicI9kc3NidHjlJHJi[zFiaX7hZ5RqfmG2aX;uJIlv\HWlZXSgZpkhTU2DUD3JTS=> MknjNlY{PThyM{m=
INA-6 M1v1XWNmdGxiVnnhZoltcXS7IFHzd4F6 NF3OVmQxNTFyMDFOwG0> NFn5Zm84OuLCiXi= NFnsbW9qdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> MYWyOlMxPjZ{NB?=
OPM-2 M{LlcWNmdGxiVnnhZoltcXS7IFHzd4F6 NHH0dFYxNTFyMDFOwG0> MVG3NwKBkWh? M17qcIlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 MnP3NlY{ODZ4MkS=
U266 NIXaOmVE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NFjye24xNTFyMDFOwG0> MYm3NwKBkWh? MYLpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= MlG1NlY{ODZ4MkS=
H929 MnX5R4VtdCCYaXHibYxqfHliQYPzZZk> MXewMVExOCEQvF2= NILCeYg4OuLCiXi= MWHpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= Mkf0NlY{ODZ4MkS=
RPMI 8226 MYTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MkTTNE0yODBizszN M4TmNFcz6oDLaB?= M1;1PIlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 M4WyUFI3OzB4NkK0
MDCK  MVLGeY5kfGmxbjDBd5NigQ>? MUWxNEDDvU1? NGfhO|czPCCq MVnEUXNQ M2nRZZVxemWpdXzheIV{KHSqZTDlfJBz\XO|aX;uJI9nKFSJRj5OtlEh[W6mIFPUS2bDqA>? MnK4NlYzODJ|NUK=
MDCK  Moi0SpVv[3Srb36gRZN{[Xl? Mm\LNVAhyrWP MkLwNlQhcA>? MX3EUXNQ MlXLbY5pcWKrdIOgeIhmKGmwY4LlZZNm\CCneIDy[ZN{cW:wIH;mJGZPKGOjdYPl[EBjgSCWR1[t{tIy MmX4NlYzODJ|NUK=
Spinal cords  NIeyN3JHfW6ldHnvckBCe3OjeR?= MV6xxsDPxE1? M{HkR|MxKG2rbh?= NFjTVYt{fGmvdXzheIV{KGODTWCgcIV3\Wy| NWrVOld6OjZzMk[5NlY>
BeWo  MmjnSpVv[3Srb36gRZN{[Xl? NF3DTW0zPeLCid88US=> M3\pcFI1NzR6L{eyJIg> MXrs[YFleyC2bzDhckBqdmO{ZXHz[UBqdiC2aHWg[ZhxemW|c3nvckBw\iCxdHjldkBnfXOrb36gcYFzc2W{cx?= M2KzdFI3ODV|NUS5
bovine oocytes NXrMN2U{TnWwY4Tpc44hSXO|YYm= NWn2RYhJOTBywrFOwG0> NFHDToQyOsLiaB?= MkfLbY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCQUGDBJIFv\C:xcjDOVHBEKHSxIIP0bY12dGG2ZTDy[ZN2dXC2aX;uJI9nKG2naX;zbZM> M3jxXVI3ODVzNkGx
Caco-2  MojpSpVv[3Srb36gRZN{[Xl? M{PVbVAvOS9zL{GwJO69VQ>? NVvuTGI2OjEEoH3pci=> M1jnWIlv\HWlZYOgZUBld3OnLXTldIVv\GWwdDDpcoNz\WG|ZTDpckBqdnS{YXPlcIx2dGG{IHPBUXAhdGW4ZXzz NX\mNWNLOjZyNEmxNFI>
Caco-2  NVz4b4s4TnWwY4Tpc44hSXO|YYm= M4jnOlAvOS9zL{GwJO69VQ>? Mmf2NlQhcA>? NGP0dXpqdmO{ZXHz[ZMhVVKSMjDwdo91\WmwIHzleoVt NH\X[m0zPjB2OUGwNi=>
AML-12  NWHiSHJNTnWwY4Tpc44hSXO|YYm= NHHrboEzOCEQvF2= M2XF[|MhcA>? NYTydHhRfXC{ZXf1cIF1\XNidHjlJJBpd3OyaH;yfYxifGmxbjDs[ZZmdHNiYYSgWIhzNTRzMTDhcoQhW2W{LUS5Ny=> MUOyOlA1QDl6NR?=
AML-12  MVLGeY5kfGmxbjDBd5NigQ>? MViyNEDPxE1? Ml\TNU05KGh? M3jDSolv[3KnYYPld{BodHWlb4PlJJBzd2S3Y4Tpc44> M1TCVFI3ODR6OUi1
AML-12  MVTGeY5kfGmxbjDBd5NigQ>? MojMNlAh|ryP NGXxV4s{KGh? MVT1dE1z\We3bHH0[ZPDqFCpY{HhMOKhWGWyY3usJIFv\MLiR{\wZ:KhdVKQQTDs[ZZmdHN? MlfaNlYxPDh7OEW=
AML-12  NITMN|dHfW6ldHnvckBCe3OjeR?= MV:yNEDPxE1? NXHYboFCOyCq MXLpcoR2[2W|IITo[UBl\XCqb4PwbI9zgWyjdHnvckBw\iCFUmTDNuKh Mon5NlYxPDh7OEW=
RBMECs MWfGeY5kfGmxbjDBd5NigQ>? NYf5OWZ5PcLizszN Ml\yNUBp NHnxPFdqdmirYnn0d{BGVUGSLVnJMYlv\HWlZXSgbY5i[3SrdnH0bY9vKG:oIGLhdFHDqA>? NUX1XVR7OjZyNES2OlM>
EndoC-βH1 NUG3cI1ETnWwY4Tpc44hSXO|YYm= Mnf2OeKh|ryP Mnr1NUBp M1nTRpBwfGWwdHnheIV{KGeudXPvd4UucW6mdXPl[EBqdnO3bHnuJJNm[3KndHnvckBqdiC2aHWgdJJme2WwY3Wgc4Yh\2y3Y3;z[S=> NWfTXHJVOjZyMki1OlI>
EndoC-βH1 MWfGeY5kfGmxbjDBd5NigQ>? MkP1OeKh|ryP NEHQOo4yKGh? NUX1ZVVXdGWjZIOgeI8h[SC|dILvcoch[0GPUDDpcoNz\WG|ZR?= MljrNlYxOjh3NkK=
SH-SY5Y M4rBNWZ2dmO2aX;uJGF{e2G7 NUHUdVZWOzBizszN M2HyNFMxKG2rbh?= NX3reVVnTE2VTx?= M2\3TpNq\26rZnnjZY51dHliaX7jdoVie2W|IITo[UBi[3SrdnH0bY9vKG:oIGDLRS=> NUXKeJNNOjZyMkWxN|c>
PC-3 M1XrXmZ2dmO2aX;uJGF{e2G7 MnW5OFAhyrWP MXuyJIg> MkPVSG1UVw>? NUKyblUzdGWjZIOgeI8hWFB{QTDhZ5RqfmG2aX;u MoexNlYxOjN6M{[=
PC-3 M2rITWNmdGxiVnnhZoltcXS7IFHzd4F6 NEG4Opo1OCEEtV2= M1X4Z|I1NzR6L{eyJIg> MVzEUXNQ M{[weIRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTD0bY1mKGSncHXu[IVvfGy7 MXuyOlAzOzh|Nh?=
SCG NWPCb29tTnWwY4Tpc44hSXO|YYm= M{jUNFIxKM7:TdMg MnL2SG1UVw>? NUmxdnFyemW4ZYLzbYJtgSC|dYDwdoV{e2W|IFnLWkB4cXSqIHGgTWM2OCCxZjCyOE41KM7:TR?= M{jXNVI2QTZ{MUOy
HEK-293 NVLjc4t[TnWwY4Tpc44hSXO|YYm= NWO1dJZxOzVizszNxsA> M1HkZmROW09? MYfpcoR2[2W|IHGgZ49ve3CrY4XveZMh6oDeaX7hZ5RqfmG2aX;u5qCeKG:oIITo[UBMfjJwMTDjeZJz\W62 M16xWFI2QTZ{MUOy
SCG MlPnSpVv[3Srb36gRZN{[Xl? M3\kOFExOCEQvF5CpC=> NWLEbFRNTE2VTx?= M4nlSpJm\HWlZYOgeIhmKGW6Y3n0ZYJqdGm2eTDv[kBUS0dibnX1do9vew>? NEX3UnkzPTl4MkGzNi=>
PCCL3 NUTjT4FwTnWwY4Tpc44hSXO|YYm= NVvCUmhsOTBiwsXN M3TwcFI1KGh? M{fIPIVvcGGwY3XzJGR2V3h{IIDyc41wfGW{IITyZY5{[3KrcITpc44h[WO2aY\peJnDqOLCix?= M1flOVI2QTZyOUW2
3T3-L1 preadipocytes M2rHR2Z2dmO2aX;uJGF{e2G7 MYqxNEDPxE4EoB?= NXTaS3l[OTJiaB?= NIHMO5NqdmS3Y3XzJGNTTUJicHjvd5Bpd3K7bHH0bY9vKGGwZDDDM2VDWM7{IHX4dJJme3Orb36= MXeyOVkzQDB3OB?=
H295R  MXnGeY5kfGmxbjDBd5NigQ>? NHnzeG0yOMLizszN M{jafVQ5yqCq MXnpcoNz\WG|ZYOgd5Rmem:rZDDt[ZRi[m:uaYTld{BqdiC2aHWgZY5lem:pZX6sJI1qdmW{YXzvMUBidmRiZ3z1Z49kd3K2aXPvbYQheGG2aIfhfZM> NFG1VmozPTh4OUW1Oi=>
PBMC NGrSbY1HfW6ldHnvckBCe3OjeR?= NUHNVZFyPTEEoN88US=> NIOw[24zPMLiaNMg MX7pcohq[mm2czD0bIUhcW6lcnXhd4VlKHOnY4LleIlwdiCxZjDUUmYhcW6mdXPl[EBjgSC2aHWgSHBG NWTKeWRpOjV6Nk[wO|k>
GLUTag  NEixU4dHfW6ldHnvckBCe3OjeR?= M2C1NVEx6oDLwsXN MUSwM|IwPCCq NE\IfYh{fGmvdXzheIV{KEeOUD2xJJNm[3KndHnvckBkd3S{ZXH0[YQhf2m2aDDJRm1Z MnO1NlU5OzJ4M{G=
GLUTag  MnP1SpVv[3Srb36gRZN{[Xl? MUWxNQKBkcL3TR?= NGLaPIw1KGh? NYXiSJRscW6lcnXhd4V{KHSqZTDwR3JGSiCuZY\lcJMhf2m2aDD0bIUhUUKPWB?= Ml3UNlU5OzJ4M{G=
BAECs M3jJc2Z2dmO2aX;uJGF{e2G7 M1LmU|I2KM7:TR?= NYWyWpFKOjRiaB?= MnXW[Y5p[W6lZYOgeIhmKGGldHn2ZZRqd25ib3[gVHBCWs7zIHL5JFUh|ryPIILld5ZmemG2cn;sMEBVPEiVLDDvdkA1NVCDUB?= M2nGb|I2Pzl6OEK2
PC12 NFWwXpVHfW6ldHnvckBCe3OjeR?= NUfHNHFVOjYEoN88US=> NHvYclg1QCCq M1rzSoFkfGm4YYTld{BkSU2S MmnCNlU4Pjl|MEW=
GH3 NX32eVVtTnWwY4Tpc44hSXO|YYm= MXixxsDPxE1? MofJOk1p M3ezOIF1fGWwdXH0[ZMhfGinIHPvdpJmdGG2aX;uJIJmfHenZX6gVHJNKGGwZDDCcYFtOSCneIDy[ZN{cW:w NXPzcXYyOjV5MkewNVg>
GH3 MYrGeY5kfGmxbjDBd5NigQ>? MoGwNeKh|ryP MUW2MYg> MVHpcoR2[2W|IGDSUEBidmRiQn3hcFEtKGK3dDDuc5QhS2yxY3usJI1TVkFiZYjwdoV{e2mxbh?= NG\hUI4zPTd{N{CxPC=>
BeWo NX;HS|ZSTnWwY4Tpc44hSXO|YYm= MWGxNQKBks7:TdMg M1fSUFczKGh? M4PoXmROW09? MV\t[YRq[XSnczDC[XdwKGOnbHyg[Iln\mW{ZX70bYF1cW:w M1juRlI2PzF|NEK1
oocytes MmrMSpVv[3Srb36gRZN{[Xl? MWK1JO69VQ>? NVvn[ZEyOjRiaB?= MUnheJRmdnWjdHXzJJJpNWmwc4XsbY4h[WO2aX;uJI9vKG:xY4n0[UBIXkKGIIPp[45q\mmlYX70cJnDqA>? NXzTTYlbOjV5MEe4OVQ>
SC NF;mR3lHfW6ldHnvckBCe3OjeR?= M4C1NlAvPSEQvF2= M2KwVlI1KGh? MorjcYlucWOtczD0bIUh\W[oZXP0JI9nKGODTWCgZY5idG:pczDvckBQOSCjbnSgUWJRKGW6cILld5Nqd25? M1Xs[|I2PzB3OEe0
SC M{nLZWZ2dmO2aX;uJGF{e2G7 M2jWNFAvPSEQvF2= NULoWIpCPzJiaB?= MUDpcoNz\WG|ZYOgZo91cCCNcn;4MVIxKGGwZDDPNUBmgHC{ZYPzbY9vKGmwIHH4c44uemWuYYTl[EBUS3NiYoX0JI9vdHliS4LvfE0zOMLi NYr4V2ZGOjV5MEW4O|Q>
UACC-647  NUnPNJM2TnWwY4Tpc44hSXO|YYm= M3\EemROW09? M{fMeIxm[WS|IITvJIEhemm|ZTDpckBkSU2SIHzleoVteyBqRVO1NOKhRcLiMkCuN|nDqM7:TTm= NFSwXIEzPTdyM{CyOS=>
UACC-647  M4HXNWZ2dmO2aX;uJGF{e2G7 NH\tR4gyOMLizszN NVXMOYFYOTVibXnu NHPxO2hFVVOR MUTpcohq[mm2czDFVmsheGixc4Doc5J6dGG2aX;u NGK2UXYzPTdyM{CyOS=>
UACC-647  MoXQSpVv[3Srb36gRZN{[Xl? MnPjNVDDqM7:TR?= NHHNZlQyPSCvaX6= Ml3iSG1UVw>? M3H5VIlv[3KnYYPld{BmTUZ{IIDoc5NxcG:{eXzheIlwdiCuZY\lcJPDqA>? Ml;FNlU4ODNyMkW=
SH-SY5Y  MVPGeY5kfGmxbjDBd5NigQ>? MUCxNOKh|ryP NIO4cI4yyqCqwrC= MYfpcoNz\WG|ZYOgUHVEKGGldHn2bZR6 NFXXNpIzPTV7N{SzNy=>
SH-SY5Y  NF7HSZdHfW6ldHnvckBCe3OjeR?= NIqyelgyOMLizszN M1;seVHDqGkEoB?= M1fuSYlv[3KnYYPld{BCT0NzIH3SUmEhdGW4ZXy= MUeyOVU6PzR|Mx?=
hADSCs MYDGeY5kfGmxbjDBd5NigQ>? M3;GRlXjiIoEtV2= MUGzNEBucW5? MnTFbY5kemWjc3XzJINCVVBibHX2[Yx{ NF24WYQzPTV7MUmwPC=>
HEK293  MoXwSpVv[3Srb36gRZN{[Xl? NVTTeVBxPeLCidM1US=> M4jmSVMxKG2rbh?= Moi3bY5kemWjc3XzJINCVVBibHX2[Yx{ NHT5cZozPTV7MUmwPC=>
3T3-L1 NU\PdmJJTnWwY4Tpc44hSXO|YYm= NY\hdG1XOi53L{Wg{txO NHT1dXczPCCqwrC= NIHiSlJ{cWewaX\pZ4FvfGy7IHTlZ5Jm[XOnczDBWGdNKHC{b4TlbY4h\XiycnXzd4lwdiCjdDDhcIwh\G:|ZYOgeIV{fGWm MoXxNlU2QTB3OUe=
OCI-Ly1  MUTGeY5kfGmxbjDBd5NigQ>? M1;OelQxyqEQvF2= MVuxxsBpyqB? MVzEUXNQ NIGzZnlqdmS3Y3XzJJRp\SCrbnPy[Y1mdnRib3[gZ2FOWCClb37j[Y51emG2aX;udy=> M4Wxb|I2PTd4MkKw
OCI-Ly18  MlfNSpVv[3Srb36gRZN{[Xl? M{\pUlQxyqEQvF2= NEDCXXIyyqCqwrC= Mk\ESG1UVw>? NWjn[nJxcW6mdXPld{B1cGViaX7jdoVu\W62IH;mJINCVVBiY3;uZ4VvfHKjdHnvcpM> MV2yOVU4PjJ{MB?=
BeWo NW[zRnlxTnWwY4Tpc44hSXO|YYm= M2Xa[lIxyqEEtV2= M4LxUFQ5yqCq NUnrd5dPTE2VTx?= M4\Fe4lv[3KnYYPld{B1cGViZHnm[oVz\W62aXH0bY9vKG:oIFLlW48h[2WubIO= MWKyOVU3Pjd2MB?=
BeWo MUjGeY5kfGmxbjDBd5NigQ>? M1\1U|IxyqEEtV2= NX3aZWNKPDkEoHi= M3rTemROW09? NF\1bZlqdmO{ZXHz[ZMhfGinIHHkbIV{cW:wIH;mJHRJWC1zIH3vco9kgXSncx?= M2PCWFI2PTZ4N{Sw
LNCaP  NUHvNno5TnWwY4Tpc44hSXO|YYm= M2G2[lExyqEQvF2= M1n1elEzKGkEoB?= M33ac2ROW09? M3;ER4lv\HWlZYOgZUBlemGvYYTpZ{BqdmO{ZXHz[UBw\iCFUlXCNUBi[3Srdnn0fS=> NF;KZXAzPTV2OEC5PS=>
ThGCs  MWDGeY5kfGmxbjDBd5NigQ>? NHvhNIIyOOLCit88US=> NF7xdo016oDMaB?= Ml\qZZVodWWwdIOgTGlHOUFibHX2[Yx{KHSqYYSge4Vz\SC|dHnteYxifGWmIHL5JGNwS2x{ MnnQNlU1OzNyMke=
ThGCs  MlnxSpVv[3Srb36gRZN{[Xl? MYOxNQKBks7:TR?= NEHKfpg16oDMaB?= M2KyO4lv[3KnYYPld{BEd0OuMj3pcoR2[2WmIFXEUlLDqGenbnWg[ZhxemW|c3nvci=> Mn;4NlU1OzNyMke=
ThGCs  NYTORWJGTnWwY4Tpc44hSXO|YYm= NWewR|VwOTEkgJtOwG0> MXuzJIg> MlTqbY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCKMl:yJI9vKEWGTkKgcXJPSQ>? MV[yOVQ{OzB{Nx?=
RBMECs NIWxeG9HfW6ldHnvckBCe3OjeR?= MUmwMlA2NzBwNT:1JO69VQ>? NYDBO|MzOC5{NTDo NVH0TGVHcW6lcnXhd4V{KGODTWCgZ49v[2WwdILheIlwdg>? MXmyOVQyPjZ3MR?=
RBMECs M{TPfWZ2dmO2aX;uJGF{e2G7 Mn\ZOeKh|ryP NUnjc|htOSCq NYnpUYlI[myxY3vzJJRp\SCjY4TpeoF1cW:wIH;mJHJpd0FxUl;DT{BqdmS3Y3XkJIJ6KEWPQWCtTWk> MXyyOVQyPjZ3MR?=
RBMECs NHn2b45HfW6ldHnvckBCe3OjeR?= NYnmN|RWPcLizszN M4L2elEhcA>? MU\wdoV3\W62czD0bIUhTU2DUD3JTU1qdmS3Y3XkJHRGTVJidnHseYUh\GWlcnXhd4U> MmLxNlU1OTZ4NUG=
RBMECs M4HVeWZ2dmO2aX;uJGF{e2G7 NUPaVGE2PcLizszN NVvPW5BuOSCq NVPPVHlteHKndnXueJMhfGinIHnuZ5Jm[XOnIHnuJGhTWCCobIX4JIFkem:|czD0bIUhSlSEIHnu[JVk\WRiYomgJGVOSVBvSVm= NEfzVGMzPTRzNk[1NS=>
RBMECs Mln2SpVv[3Srb36gRZN{[Xl? NXXzeG9SPcLizszN M162OVEhcA>? M3m1RYlvcGmkaYTzJJRp\SCmZXPy[YF{\WRib3[gZY1wfW62IH;mJHpQNTFiaX6gUWZ{KGmwZIXj[YQh[nliRV3BVE1KUQ>? M1LmPVI2PDF4NkWx
RBMECs NILzWW5HfW6ldHnvckBCe3OjeR?= MYe1xsDPxE1? Mn7qNUBp NX;yflhUemW4ZYLz[ZMhfGinIHPoZY5o\XNiaX6gXm8uOSCmaYP0doljfXSrb36gd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70 Mn\WNlU1OTZ4NUG=
RBMECs NXTRU3JFTnWwY4Tpc44hSXO|YYm= M3rlZlXDqM7:TR?= NXPlUY9HOSCq M1T2eIJtd2OtczD0bIUhTU2DUD3JTU1qdmS3Y3XkJINp[W6pZTDpckBOVENicHjvd5Bpd3K7bHH0bY9v NUnacZlbOjV2MU[2OVE>
RBMECs Ml;CSpVv[3Srb36gRZN{[Xl? MUK1xsDPxE1? MojnNUBp M1;5[YJtd2OtczD0bIUh[WO2aX6gZ5l1d3OtZXzleI9vKHKnYYLyZY5o\W2nboSgd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70xsA> MYmyOVQyPjZ3MR?=
Primary bovine chondrocytes NWXLSlBTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHvdHB1Pc7:TR?= NWDkXmpWPDhiaB?= M3\uUpJmfmW{c3XzJJRp\SCrbnjpZol1d3K7IHXm[oVkfCCxZjDj[Yxm[2:6aXKgc44heHKxbHnm[ZJifGmxbjDpckBoem:5dHigdIxifGViY3jvcoRzd2O7dHXz M1rKZ|I2PDB4MEG2
EM1  NGjGUGNHfW6ldHnvckBCe3OjeR?= NYj0eGw5OTYkgJtOwG0> NX;HR4RLPDhiaB?= NYG4cGNJemWmdXPld{B1cGViZYjwdoV{e2mxbjDv[uKhVEmIwrDvduKhWFSJU{NCpIlvyqCFQVzSMUBwesLiRWDBR|Iue2muZX7j[YQhTU1zIHPlcIx{yqB? MYqyOVM4QDZ4MR?=
BeWo  Mn7mSpVv[3Srb36gRZN{[Xl? MoH1NlDDqML3TR?= MkD6OFjDqGkEoB?= NXvvbIdWTE2VT9Mg NI\n[IdqdmO{ZXHz[ZMhfGinIHLleIEucEOJIILlcIVie2V? M2S2eFI2OzZ{Mk[w
BeWo  NIfGeZdHfW6ldHnvckBCe3OjeR?= M3;2NVIxyqEEtV2= M2L5dFQ5yqCqwrC= MlzySG1UV8Li Mnvn[I94dnKnZ4XsZZRmeyC2aHWgcIV3\Wxib3[gWG1GVUZzNh?= MYmyOVM3OjJ4MB?=
BeWo  Mom4SpVv[3Srb36gRZN{[Xl? NYLqbHZzOjEEoNM1US=> MlnOOFjDqGkEoB?= NV;pZXluTE2VT9Mg MnLZ[I94dnKnZ4XsZZRmeyC2aHWgcIV3\Wxib3[gS2NONTF? NH7nO|QzPTN4MkK2NC=>
granulosa cells NXvPVWdvTnWwY4Tpc44hSXO|YYm= NYjNXnBXOTBizszN M3XuNlEzNzJ2IHi= NYrmW2dIcW6lcnXhd4V{KHSqZTDs[ZZmdHNib3dCpHJIWzMEoH3SUmE> MVWyOVM{QTFyNR?=
granulosa cells M4jOfWZ2dmO2aX;uJGF{e2G7 M3XwTVExKM7:TR?= MoTKNVIwOjRiaB?= M2fTOYlv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= MX2yOVM{QTFyNR?=
granulosa cells MX;GeY5kfGmxbjDBd5NigQ>? MlvRNVAh|ryP MmjzNlQhcA>? NEeyc25qdmO{ZXHz[ZMhfGinIHnueIVve2m2eTDv[kBFVkFxcILveIVqdiClb33wcIV5 MlPENlU{OzlzMEW=
granulosa cells MYfGeY5kfGmxbjDBd5NigQ>? MXSxNEDPxE1? NVLOXXY4OjRiaB?= MXfpcoNz\WG|ZYOgeIhmKGyndnXsd{Bw\iCUR2OyJJBzd22xdHXyJIFkfGm4aYT5 NXLRW4ZuOjV|M{mxNFU>
SK-N-AS  MlnQR4VtdCCYaXHibYxqfHliQYPzZZk> NXu2[YhROTBizszNxsA> MV[yOE81QCCq NFT5OGtmdmijbnPld{B1cW2nLXTldIVv\GWwdHz5JINmdGy3bHHyJJZq[WKrbHn0feKh NEjDb|QzPTJ4NkC2Ny=>
SK-N-AS  M3TPV2Z2dmO2aX;uJGF{e2G7 MkKzNVAh|ryPwrC= MXiyOEBp NVL5RoVGcW6lcnXhd4V{KHSqZTDjRW1RKGyndnXsd:Kh MnntNlUzPjZyNkO=
SK-N-AS  NEPXeIRHfW6ldHnvckBCe3OjeR?= NXyy[4czOTBizszNxsA> MnPJNlQhcA>? NVLCU4hycW6lcnXhd4V{KHSqZTDlfJBz\XO|aX;uJI9nKGO7Y3zpckBFOQ>? NU\W[pNGOjV{Nk[wOlM>
SK-N-AS  M2rMXGZ2dmO2aX;uJGF{e2G7 M1zPO|ExKM7:TdMg MY[zNEBucW5? M4PXbolv\HWlZYOgdIhwe3Cqb4L5cIF1cW:wIH;mJO6zNWOjdHXubY4hMHOnck[3OUktKHBvR2PLN:6zKCi|ZYK5LUBidmRiY3;uZ49ucXSjboSgbIlocGW{IHzleoVteyCxZjDhZ5RqfmVuIIXudIhwe3Cqb4L5cIF1\WRuIN8yMYNifGWwaX6= NHTCfHUzPTJ4NkC2Ny=>
SK-N-AS  NIrnOW1HfW6ldHnvckBCe3OjeR?= M3XnUlExKM7:TdMg MV:xNE8{OC94MDDtbY4> NELZWlRqdmO{ZXHz[ZMhdGW4ZXzzJI9nKHBvzsKtZ4F1\W6rbjCod4VzPjd3KTDhcoQhcW6mdXPld{Bi[2O3bYXsZZRqd25ib3[gdE3Pui2lYYTlcolvKCi|ZYK2O|UqKGmwIDjw[ZJqMW63Y3zlZZIhemWpaX;udy=> M1\wNlI2OjZ4ME[z
SK-N-SH MkHjR4VtdCCYaXHibYxqfHliQYPzZZk> MlLkNVAh|ryPwrC= M3yxPFQ5KGh? NWHGeGhi\W6qYX7j[ZMhW0tvTj3TTEBv\XW{b3LsZZN1d22jIHPlcIwhfmmjYnnsbZR6 NFHIXmYzPTJ4NkC2Ny=>
HEK‐CFTR NFrrSYNHfW6ldHnvckBCe3OjeR?= M1LwT|LjiJN3MNMg{txO MWOwMVEzKG2rbh?= M4f1RWROW00EoB?= MWfpcoR2[2W|IHGg[I9{\eLCkHTldIVv\GWwdDDpc4Rq\GViZX\mcJV5yqB? NIfrSmczPTJ4M{KwOy=>
L6 Mm\FSpVv[3Srb36gRZN{[Xl? MVG0NEDDvU1? MYGyOEBp M33OWIlvcGmkaYTzJGROUDFvaX7keYNm\CCDa4SgZYN1cX[jdHnvci=> MorCNlUzPDd3NUC=
MIN6  Mn;TSpVv[3Srb36gRZN{[Xl? Mmm2NVAh|ryPwrC= MXqzJIg> NE\pRo9qdmO{ZXHz[ZMhTDNibWLORUBmgHC{ZYPzbY9v MXiyOVI1OTF{NB?=
ventricular cardiomyocytes  M{H5fWZ2dmO2aX;uJGF{e2G7 MljsNE4xOS1zMDFOwG0> NHLwWJRqdmO{ZXHz[ZMhKGODTWCgZYNkfW23bHH0bY9v M1fOT|I2OjB|MUGz
ventricular cardiomyocytes  MoXmSpVv[3Srb36gRZN{[Xl? M3:4V|AvODFvMUCg{txO Mln3[ZZwc2W|IHHuJIlvd3S{b4DpZ{Bz\XOyb37z[UAyOjEEsUG1KUBi[m:4ZTDiZZNidCC5aYToJIFvKEWFNUFCpI9nKDJwMjFCuW0> MoL5NlUzODNzMUO=
BeWo  NEjsW|ZHfW6ldHnvckBCe3OjeR?= NXzOR3g5OjBiwsXN NEW0d3E1QCCq NILHZolFVVORwrC= MmjHbY5lfWOnczDj[YxtKG[3c3nvci=> MmDyNlUyQDR2N{e=
THP-1  MX3GeY5kfGmxbjDBd5NigQ>? MXqxM|ExKM7:TR?= MYWyxsBp M{LUXmROW00EoB?= M2X6V5N2eHC{ZYPz[ZMhVUOSLUGgdJJw\HWldHnvcuKh M4m3[VI2OTV2OEiy
Huh-7 NG\jSFFHfW6ldHnvckBCe3OjeR?= M1\mWFAuOjBizszN MmjmNkBpyqB? MlX1doV{fWy2czDpckBiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGNvTYnjJIV5eHKnc4Ppc44h[XRidHjlJJBzd3SnaX6gZY5lKG2UTlGgcIV3\Wy| MVmyOVExQTh|NB?=
C6 NFL6eINHfW6ldHnvckBCe3OjeR?= NILGUnEyOCEQvF5CpC=> Mkn6NlAhdWmw NHPQS2hqdmO{ZXHz[ZMh[0GPUDDhZ4N2dXWuYYTpc44> MYCyOVA3QTRzNx?=
SW480 NVzLfI57TnWwY4Tpc44hSXO|YYm= MXm0NOKh|ryP MXu0POKhcA>? MlnuSG1UVw>? MnzNZYN1cX[jdHXzJHBROkF? NGPZVm4zPDl7N{S1NS=>
HT-29  MojkSpVv[3Srb36gRZN{[Xl? M1OzWFQxyqEQvF2= NX7hRYZoPDkEoHi= MorySG1UVw>? M2PmeoFkfGm4YYTld{BRWDKD MXuyOFk6PzR3MR?=
SW480 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1XpTFQxyqEQvF2= M4my[|AuPzJiaB?= MXnEUXNQ MXnpcohq[mm2czDj[YxtKGe{b4f0bEB1cW2nIHTldIVv\GWwdHz5 NGrpbJYzPDl7N{S1NS=>
HT-29  M4O0NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV7VdZFmPDEEoN88US=> M1\FRlAuPzJiaB?= NGXi[4ZFVVOR NYC3c2xycW6qaXLpeJMh[2WubDDndo94fGhidHnt[UBl\XCnbnTlcpRtgQ>? NYDwdVBqOjR7OUe0OVE>
SW480 Mm\2SpVv[3Srb36gRZN{[Xl? M4C1d|QxyqEQvF2= M1;RT|ch\A>? MnjYSG1UVw>? NIPTUVVz\WS3Y3XzJINwdG:wb4PwbIVz\SCob4LtZZRqd25iY3HwZYJqdGm2edMg Ml\FNlQ6QTd2NUG=
HT-29  M2\Hd2Z2dmO2aX;uJGF{e2G7 M33HSlQxyqEQvF2= NYDS[llTPyCm NEfDV4lFVVOR M3vFTpJm\HWlZYOgZ49td26xc4Do[ZJmKG[xcn3heIlwdiClYYDhZoltcXS7wrC= NISzRVMzPDl7N{S1NS=>
SW480 MX\BdI9xfG:|aYOgRZN{[Xl? MU[0NOKh|ryP M{\hflQ5yqCq MkPvSG1UVw>? MULpcoR2[2W|IHHuJIFkfGm4YYTpc44hd2ZiY3HzdIF{\SB|L{e= Mlq0NlQ6QTd2NUG=
HT-29  M{XGb2Fxd3C2b4Ppd{BCe3OjeR?= MV60NOKh|ryP MoPyOFjDqGh? M3TqcGROW09? MXXpcoR2[2W|IHHuJIFkfGm4YYTpc44hd2ZiY3HzdIF{\SB|L{e= NHi1cJAzPDl7N{S1NS=>
SW480 MnjoRZBweHSxc3nzJGF{e2G7 M4XJZlQxyqEQvF2= MXS0POKhcA>? M2rSZmROW09? MmXqbY5lfWOnczDjbIFv\2W|IHnuJJRp\SCyaH;zdIhwenmuYYTpc44he3SjdIXzJI9nKFCSMlGgeIFz\2W2cx?= NH7ZToMzPDl7N{S1NS=>
HT-29  MmXlRZBweHSxc3nzJGF{e2G7 M2rBflQxyqEQvF2= M1f0U|Q5yqCq MXjEUXNQ MWTpcoR2[2W|IHPoZY5o\XNiaX6geIhmKHCqb4PwbI9zgWyjdHnvckB{fGG2dYOgc4YhWFB{QTD0ZZJo\XS| MWGyOFk6PzR3MR?=

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
in solvent
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00864578 Withdrawn Primary Open Angle Glaucoma|Intraocular Pressure Sooft Italia April 2009 --
NCT00863811 Withdrawn Primary Open Angle Glaucoma|Intraocular Pressure Sooft Italia April 2009 --

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID