(+)-JQ1

目录号:S7110

(+)-JQ1 Chemical Structure

Molecular Weight(MW): 456.99

(+)-JQ1是一种BET bromodomain抑制剂,作用于BRD4(1/2),无细胞试验中IC50为77 nM/33 nM,结合到BET家族的所有溴结构域,而不结合到BET家族以外的溴结构域。

规格 价格 库存 购买数量  
RMB 2227.39 现货
RMB 4667.45 现货
有超大折扣

今日订购,明日送达,全国免运费!

全国免费电话:400-668-6834   |   Email:info@selleck.cn

客户使用该产品的9个实验数据:

  • The BET protein inhibitor JQ1 reduces c-Myc expression and attenuates primary MCC cell proliferation. A, decreased c-Myc expression in MCC-3 and MCC-5 treated with JQ1 (800 nmol/L) for 72 hours by qRT-PCR and immunoblotting. The mRNA expression of target genes was normalized to that of MRPS2 and a value of 1.0 was assigned to the mRNA expression of target genes in the control group (means+SEM; **, P < 0.01 vs. control); b-actin was used as a loading control for immunoblotting.

    Cancer Res 2014 74(23), 7090-102. (+)-JQ1 purchased from Selleck.

    Immunohistochemical staining of xenograft tumor tissues. Immunohistochemical staining of xenograft tumor tissues with the indicated antibodies. p21-, p27-, p57-, and Ki67 positive cells (brown staining) were quantified at x400 magnification (meansSEM;**, P < 0.01;***, P < 0.001 vs. control); scale bars, 10 um.

    Cancer Res 2014 74(23), 7090-102. (+)-JQ1 purchased from Selleck.

  • (D) Effect of JQ1 on alterations of actin cytoskeleton in VEGF-induced HUVECs. The cells were pretreated with DMSO or JQ1 (100 nM) for 6 h, and stimulated with VEGF (10 ng/mL) for 12 h. F-actin (red) and nuclei (blue) were stained with phalloidin and DAPI, respectively. Representative images from 3 independent experiments.

    Sci Rep, 2016, 6:23770.. (+)-JQ1 purchased from Selleck.

    Sensitivity of BEZ235-resistant cells to JQ-1 using the MTT assay.

    Oncotarget, 2016, 6(7):5134-46.. (+)-JQ1 purchased from Selleck.

  • B. Repressed MCC-3 xenograft tumor growth upon combined treatment with MLN0128 and JQ1. Tumor bearing mice were treated with MLN0128 or vehicle at 1 mg/kg/day by oral gavage and JQ1 or vehicle at 50 mg/kg/day by i.p. injection for a period of 30 days. C. A more effective reduction of MCC-3 xenograft tumor growth in the group treated with combined therapy. Fold-reduction of tumor growth was calculated as average tumor growth of control group divided by average tumor growth of treatment group. Tumor growth was calculated as final average tumor volume minus initial average tumor volume in each group.

    Oncotarget, 2016, 7(6):6576-92.. (+)-JQ1 purchased from Selleck.

    Int J Stem Cells, 2018, 11(1):131-140. (+)-JQ1 purchased from Selleck.

  • JQ1 induces cell cycle arrest and apoptosis in Cal27 cells. (C) Cal27 cells were treated with JQ1 for 24 h and whole cell lysates were tested by western blot assays for the expression of cleaved-caspase-3. GAPDH was used as a loading control. (D) Apoptosis of Cal27 cells treated with JQ1 at 0 and 0.5 µM JQ1; *P<0.05 vs. control (the DMSO group)

    Oncol Rep, 2016, 36(4):1989-96.. (+)-JQ1 purchased from Selleck.

    immunofluorescence staining of BRD4 in ACC-LM and ACC-83 cells treated with JQ1 at the concentration of 1 µM for 24 h (×200).

    Biol Res, 2017, 50(1):19. (+)-JQ1 purchased from Selleck.

  • Effect of BET domain family inhibition on AMI damage in cardiomyocytes. (A) LDH and (B) CK-MB activity in the serum. #P<0.01 vs. sham group; @P<0.05 and &P<0.01 vs. AMI group. BET, bromodomain and extra-terminal; AMI, acute myocardial infarction; LDH, lactate dehydrogenase; CK-MB, creatine kinase MB isoenzyme.

    Exp Ther Med, 2015, 10(6):2319-2324.. (+)-JQ1 purchased from Selleck.

产品安全说明书

Epigenetic Reader Domain抑制剂选择性比较

生物活性

产品描述 (+)-JQ1是一种BET bromodomain抑制剂,作用于BRD4(1/2),无细胞试验中IC50为77 nM/33 nM,结合到BET家族的所有溴结构域,而不结合到BET家族以外的溴结构域。
特性 (+)-JQ1比(-)-JQ1更有效。
靶点
BRD4 (2) [1]
(Cell-free assay)
BRD4 (1) [1]
(Cell-free assay)
33 nM 77 nM
体外研究

(+)-JQ1对映体直接结合到BET bromodomain结构域的Kac结合位点。(+)-JQ1(500 nM)与染色质竞争性结合到BRD4,导致NMC细胞分化和生长停滞。通过Ki67染色减少,证明了(+)-JQ1(500 nM)减弱NMC 797和Per403细胞系的快速增殖。(+)-JQ1(500 nM)作用于NMC 797细胞,有效降低BRD4靶基因的表达。(+)-JQ1作用于NMC 11060细胞,抑制细胞活力, IC50为4 nM。[1](+)-JQ1作用于MM细胞系,强抑制MYC表达。(+)-JQ1抑制KMS-34和LR5增殖,IC50分别为 68 nM和98 nM。(+)-JQ1(500 nM)处理MM.1S细胞,导致S期细胞比例明显下降,随之细胞停滞在G0/G1期增多。(+)-JQ1(500 nM)通过β-半乳糖苷酶染色,导致明显的细胞衰老。(+)-JQ1(800 nM)处理CD138+病患衍生的MM样本,显著降低细胞活力。[2] (+)-JQ1抑制LP-1细胞生长,GI50 为98 nM。(+)-JQ1(625 nM)导致LP-1细胞在G0/G1期的百分数增高。(+)-JQ1(500 nM)作用于LP-1细胞,抑制MYC, BRD4 和CDK9表达。[3](+)-JQ1(1 μM)处理潜伏感染的Jurkat T细胞,激活HIV转录。(+)-JQ1(50 μM)作用于Jurkat和HeLa细胞,主要刺激Tat依赖性的HIV转录。(+)-JQ1(5 μM)作用于J-Lat A2细胞,诱导Brd4解离,从而使Tat招募SEC到HIV启动子上,诱导Pol II CTD磷酸化和病毒转录。[4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K1  NEHFcYVE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NH3E[YwzPTBxNUCwM|ExODBibl2= NHSxUHozPC92OD:3NkBp M2ftemROW09? M3\hZYlvcGmkaYTzJINmdGxidnnhZoltcXS7IHnuJIJwfGhiZH;z[U0h[W6mIITpcYUuKGSncHXu[IVvfCCvYX7u[ZI> MXSyOlcxPzh6MR?=
BCPAP M{j3dGNmdGxiVnnhZoltcXS7IFHzd4F6 NGT0PW8zPTBxNUCwM|ExODBibl2= MV6yOE81QC95MjDo MXTEUXNQ NF25bnlqdmirYnn0d{Bk\WyuII\pZYJqdGm2eTDpckBjd3SqIHTvd4UuKGGwZDD0bY1mNSCmZYDlcoRmdnRibXHucoVz NE\PRoQzPjdyN{i4NS=>
K1  M3z6[GNmdGxiQ4njcIUhSXO|YYm= NGXmbHkzPTBxNUCwM|ExODBibl2= MVi3NkBp NGLVSFVFVVOR MnPxZZJz\XO2czDj[YxtKGO7Y3zlJIF1KEdyL1exJJBp[XOn MnX1NlY4ODd6OEG=
BCPAP MVLD[YxtKEO7Y3zlJGF{e2G7 M3rJXlI2OC93MECvNVAxOCCwTR?= M4jyeVczKGh? NH\5fZpFVVOR NHrpU2pienKnc4TzJINmdGxiY4njcIUh[XRiR{CvS|EheGijc3W= NFn5XZQzPjdyN{i4NS=>
Hep3B NXzlNlV6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDGNE0yOCEQvF2= NV3C[mVCPSCm NX\wVo5WTE2VTx?= M4PlPWlEPTB;MD6wPEDPxE1? NW\2bpE4OjZ3N{WxOlc>
HCCLM3 M{\zUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NESwUlcxNTFyIN88US=> MoXLOUBl NEe5WYVFVVOR NXn2RWFSUUN3ME2wMlE1KM7:TR?= MoDpNlY2PzVzNke=
HuH7 MoPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrkRnZLOC1zMDFOwG0> NXTURlhWPSCm NFHvTZpFVVOR MWXJR|UxRTBwMkGg{txO MXKyOlU4PTF4Nx?=
HepG2 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHRNE0yOCEQvF2= NEPve4Y2KGR? MnfUSG1UVw>? MlzUTWM2OD1yLkO0JO69VQ>? MYGyOlU4PTF4Nx?=
SMMC7721 M{fSW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXyzVI5ZOC1zMDFOwG0> M3zXe|Uh\A>? M1\RT2ROW09? MmPMTWM2OD1yLkSxJO69VQ>? NXLH[VNWOjZ3N{WxOlc>
BEL7402 NYTkPZJbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DMOFAuOTBizszN MVi1JIQ> NWTXXHpNTE2VTx?= NF\tPIZKSzVyPUCuOFch|ryP M1[4[lI3PTd3MU[3
MHCC97H M3r2Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVzlNlJyOC1zMDFOwG0> NGraeZo2KGR? MkPqSG1UVw>? NXrRblV1UUN3ME2wMlQyKM7:TR?= NX\SPYZJOjZ3N{WxOlc>
Hep3B M4G2eWNmdGxiQ4njcIUhSXO|YYm= NI[wbHgxNjFxMD61M|IvPSEQvF2= NUjOdnduPDhiaB?= MmLhSG1UVw>? NIW3fodt\WGmczD0c{BiKHO3YoP0ZY51cWGuIHHjZ5VufWyjdHnvckBw\iCKQ1OgZ4VtdHNiaX6gd5VjNUdzIIDoZZNmyqB? NEnhV3AzPjV5NUG2Oy=>
HCCLM3 NX;NTnNQS2WubDDDfYNt\SCDc4PhfS=> M2DHNVAvOS9yLkWvNk42KM7:TR?= NXnYOWQ4PDhiaB?= NGTrfI1FVVOR M{e5OYxm[WS|IITvJIEhe3Wkc4ThcpRq[WxiYXPjeY12dGG2aX;uJI9nKEiFQzDj[YxteyCrbjDzeYIuTzFicHjhd4XDqA>? NYXNV4JsOjZ3N{WxOlc>
Hep3B MoHqRZBweHSxc3nzJGF{e2G7 MkGyNE4yNzBwNT:yMlUh|ryP NHnWU5M1QCCq NWDCVVRlTE2VTx?= M{P4bYFkfGm4YYTld{Bk[XOyYYPlMVMh[W6mIHPhd5Bie2VvOTDlfJBz\XO|aX;uJIFv\CCrbnT1Z4VlKFCDUmCgZ4xm[X[jZ3WgZZMhf2WubDDhd{BkgXSxY3jyc41mKGNicnXs[YF{\SCrboTvJJRp\SCleYTvdIxie21iZoLvcUBucXSxY3jvcoRzcWF? MnnwNlY2PzVzNke=
HCCLM3 Ml25RZBweHSxc3nzJGF{e2G7 M3vUS|AvOS9yLkWvNk42KM7:TR?= NUPRc4szPDhiaB?= NEjy[mRFVVOR M{jSNYFkfGm4YYTld{Bk[XOyYYPlMVMh[W6mIHPhd5Bie2VvOTDlfJBz\XO|aX;uJIFv\CCrbnT1Z4VlKFCDUmCgZ4xm[X[jZ3WgZZMhf2WubDDhd{BkgXSxY3jyc41mKGNicnXs[YF{\SCrboTvJJRp\SCleYTvdIxie21iZoLvcUBucXSxY3jvcoRzcWF? MlT2NlY2PzVzNke=
A549 MljDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4nWRlAvOS1zMDFOwG0> M4jqcFczKGh? M4rjNolvcGmkaYTzJINmdGxiZ4Lve5RpKGmwIHGg[I9{\S2mZYDlcoRmdnRibXHucoVz NYTj[nhCOjZ2MUWyNlU>
H157 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MonQNE4yNTFyIN88US=> MoP3O|IhcA>? MX7pcohq[mm2czDj[YxtKGe{b4f0bEBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7ldi=> MWSyOlQyPTJ{NR?=
H1299 NH\MTHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUWwMlEuOTBizszN NIPIUVY4OiCq MWLpcohq[mm2czDj[YxtKGe{b4f0bEBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7ldi=> MoPWNlY1OTV{MkW=
A549 NXLUNYUyTnWwY4Tpc44hSXO|YYm= MoL3NU8zNjVxNTFOwG0> MVqxNkBp NHTCbIzDqHenYXvsfUBl\WO{ZXHz[YQhSmOuLUKgcIV3\Wy| NXS4S3BvOjZ2MUWyNlU>
H1299 MnvySpVv[3Srb36gRZN{[Xl? MVmxM|IvPS93IN88US=> NXvLSIRtOTJiaB?= M13Pb:Khf2Wja3z5JIRm[3KnYYPl[EBD[2xvMjDs[ZZmdHN? M3\JUFI3PDF3MkK1
H157 NVrrfW9VTnWwY4Tpc44hSXO|YYm= MVexM|IvPS93IN88US=> NFrPS5AyOiCq NED3fWpl\WO{ZXHz[YQhTFJ2IHX4dJJme3Orb36= MnjSNlY1OTV{MkW=
H1299 NF24e4xHfW6ldHnvckBCe3OjeR?= NYTDWGxIOS9{LkWvOUDPxE1? M1P2NFEzKGh? Mnvs[IVkemWjc3XkJGRTPCCneIDy[ZN{cW:w NXfDXpZ1OjZ2MUWyNlU>
C8161 MWHD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M3v0dlAuOiEQvF2= M2PWbVQh\A>? MXjEUXNQ NHnFUlZl\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= M2TLclI3Ozl5MkKz
Mel285 NID5SZJE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NYDkZ5p5OC1{IN88US=> NHTYXoc1KGR? NVG1elNwTE2VTx?= MVjk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHliaX6gZUBld3OnLXTldIVv\GWwdDDtZY5v\XJ? NVPvUnlwOjZ|OUeyNlM>
Mel290 NI\nS29E\WyuIG\pZYJqdGm2eTDBd5NigQ>? MWWwMVIh|ryP NVjXeId5PCCm NF\jSXhFVVOR MUfk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHliaX6gZUBld3OnLXTldIVv\GWwdDDtZY5v\XJ? NHPST|gzPjN7N{KyNy=>
92.1 M2TSOWNmdGxiVnnhZoltcXS7IFHzd4F6 NH;6[IkxNTJizszN Moq1OEBl M3fkcGROW09? MWrk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHliaX6gZUBld3OnLXTldIVv\GWwdDDtZY5v\XJ? M3S3dVI3Ozl5MkKz
Omm1.3 M1raWWNmdGxiVnnhZoltcXS7IFHzd4F6 NX7xfnF[OC1{IN88US=> M4PqWlQh\A>? NVTBeYRvTE2VTx?= NHu1Nlhl\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= M4HVe|I3Ozl5MkKz
Mel202 M3TTOmNmdGxiVnnhZoltcXS7IFHzd4F6 NX3XblU5OC1{IN88US=> MUe0JIQ> NUjhOnNRTE2VTx?= Mkft[IVkemWjc3XzJINmdGxidnnhZoltcXS7IHnuJIEh\G:|ZT3k[ZBmdmSnboSgcYFvdmW{ NYn2c4syOjZ|OUeyNlM>
Mel270 MoTJR4VtdCCYaXHibYxqfHliQYPzZZk> Mk[3NE0zKM7:TR?= NHj0RZo1KGR? NGPZR2dFVVOR NI[5N2ll\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= NVfDXGR3OjZ|OUeyNlM>
Omm1 NITRfYFE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NHLFV5QxNTJizszN NEn3[Gs1KGR? MVXEUXNQ M1PJUIRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= M1S3S|I3Ozl5MkKz
92.1 NYDSRWJHSXCxcITvd4l{KEG|c3H5 M4HuV|UxOCCwTR?= Mlr6OFghcA>? M4e5fWROW09? Ml7EbY5lfWOnczDhdI9xfG:|aYO= MmDINlY{QTd{MkO=
Omm1.3 NYTYXoJDSXCxcITvd4l{KEG|c3H5 MYG1NFAhdk1? M2S3WlQ5KGh? MVrEUXNQ MX7pcoR2[2W|IHHwc5B1d3Orcx?= MXyyOlM6PzJ{Mx?=
92.1 M{fDZmNmdGxiQ4njcIUhSXO|YYm= MU[1NFAhdk1? NXXVVI12OjRxNEivO|IhcA>? MmnDSG1UVw>? NGTyfJNqdmS3Y3XzJJRp\SClZXzsJIFk[3WvdXzheIlwdiCjdDDzeYIuTzIEoB?= M4rONFI3Ozl5MkKz
Omm1.3 NVTGXZkzS2WubDDDfYNt\SCDc4PhfS=> MWK1NFAhdk1? MVuyOE81QC95MjDo Mk\kSG1UVw>? M{DlOIlv\HWlZYOgeIhmKGOnbHygZYNkfW23bHH0bY9vKGG2IIP1Zk1IOcLi MXOyOlM6PzJ{Mx?=
A549 NUD5eG81TnWwY4Tpc44hSXO|YYm= NUDzeGZQOTByL{SwNE8yODByIH7N MYOyOEBp M3nEbZVxemWpdXzheIV{KGGwZDDhZ5RqfmG2ZYOgV2lTXDF? M1XWblI3OjF{MUm5
MCF-7 MU\GeY5kfGmxbjDBd5NigQ>? MnjTNVAxNzRyMD:xNFAxKG6P NHj0bnAzPCCq MUT1dJJm\3WuYYTld{BidmRiYXP0bZZifGW|IGPJVnQy Ml;SNlYzOTJzOUm=
HEK293 M3nzfWZ2dmO2aX;uJGF{e2G7 M2GzdFExOC92MECvNVAxOCCwTR?= NUPwd|FbOjRiaB?= NH\FRm12eHKnZ4XsZZRmeyCjbnSgZYN1cX[jdHXzJHNKWlRz MmS2NlYzOTJzOUm=
858 M3[3bGNmdGxiVnnhZoltcXS7IFHzd4F6 MYWwMVEh|ryP Ml\BOUBl MUfEUXNQ NFXmVXRl\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= M37qVFI3OjB4M{Oz
DDR2L63V NEn0fWVE\WyuIG\pZYJqdGm2eTDBd5NigQ>? MUKwMVEh|ryP M1vSWFUh\A>? NWOx[|R{TE2VTx?= M3X6UYRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= MWmyOlIxPjN|Mx?=
BE(2)-C MUPD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NHzjNWcyKM7:TR?= MVexMVQh\A>? NXPIRlNH\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JJNq\26rZnnjZY51dHl? MVGyOlA3PzR4NB?=
IMR-32 MlK3R4VtdCCYaXHibYxqfHliQYPzZZk> Mn25NUDPxE1? Mly4NU01KGR? M4\YWoRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDzbYdvcW[rY3HueIx6 MoHMNlYxPjd2NkS=
JF NXnxZlBWS2WubDDWbYFjcWyrdImgRZN{[Xl? NHvBVHEyKM7:TR?= MV:xMVQh\A>? MWnk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHlic3nncolncWOjboTsfS=> NWH4UpVEOjZyNke0OlQ>
BE(2)-M17 NWfxOldCS2WubDDWbYFjcWyrdImgRZN{[Xl? MX2xJO69VQ>? M{\YelEuPCCm MUXk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHlic3nncolncWOjboTsfS=> Mn\oNlYxPjd2NkS=
SK-N-SH MVXD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NEOzWngyKM7:TR?= NH\aRoQyNTRiZB?= MnTn[IVkemWjc3XzJINmdGxidnnhZoltcXS7IIPp[45q\mmlYX70cJk> NGT2RYMzPjB4N{S2OC=>
SK-N-DZ  MWPD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NXfQb|BmOSEQvF2= MnnkNU01KGR? M{izSIRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDzbYdvcW[rY3HueIx6 NYn6NXpOOjZyNke0OlQ>
HMC-1.1  M1rLW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV21MVUxODBibl2= NWn4XopiPDhiaB?= M{jkfWROW09? MU\pcohq[mm2czDj[YxtKGe{b4f0bEBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7ldi=> NFzyOXczPjB3NUOwNy=>
HMC-1.2 NVntVW9PT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPZOU02ODByIH7N NV7oPXBWPDhiaB?= M13KT2ROW09? NVzTNGpUcW6qaXLpeJMh[2WubDDndo94fGhiaX6gZUBld3OnLXTldIVv\GWwdDDtZY5v\XJ? NUO0SpdOOjZyNUWzNFM>
ROSA KIT WT  MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfwbWhTPS13MECwJI5O MVW0PEBp M3[1bmROW09? Mni4bY5pcWKrdIOgZ4VtdCCpcn;3eIghcW5iYTDkc5NmNWSncHXu[IVvfCCvYX7u[ZI> MlLhNlYxPTV|MEO=
ROSA KIT D816V NUTRVGVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LaN|UuPTByMDDuUS=> NWfVSmt4PDhiaB?= MlXVSG1UVw>? MlyzbY5pcWKrdIOgZ4VtdCCpcn;3eIghcW5iYTDkc5NmNWSncHXu[IVvfCCvYX7u[ZI> NWDsZndOOjZyNUWzNFM>
HMC-1.1  Mn7CRZBweHSxc3nzJGF{e2G7 NHvHZ4EzODBvNUCwNEBvVQ>? MVi0PEBp NXjZcGdUTE2VTx?= MoLwbY5lfWOnczDj[YxtKGGyb4D0c5NqeyCrbjDhJIRwe2VvZHXw[Y5l\W62IH3hco5meg>? NGTQZm8zPjB3NUOwNy=>
HMC-1.2 NVnCepo5SXCxcITvd4l{KEG|c3H5 MnPZNlAxNTVyMECgcm0> MmLpOFghcA>? MYLEUXNQ MnzBbY5lfWOnczDj[YxtKGGyb4D0c5NqeyCrbjDhJIRwe2VvZHXw[Y5l\W62IH3hco5meg>? NHTXXlYzPjB3NUOwNy=>
ROSA KIT WT  NGD6SI5CeG:ydH;zbZMhSXO|YYm= NG\vNo4zODBvNUCwNEBvVQ>? MkXiOFghcA>? M4nhVmROW09? NV:1[|hJcW6mdXPld{Bk\WyuIHHwc5B1d3OrczDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= M2HreFI3ODV3M{Cz
ROSA KIT D816V NHe0XXJCeG:ydH;zbZMhSXO|YYm= MoSzNlAxNTVyMECgcm0> NGrBRYY1QCCq M4[1XmROW09? NXTmRlZ4cW6mdXPld{Bk\WyuIHHwc5B1d3OrczDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= M4XnPVI3ODV3M{Cz
494H NVz6e2hpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfFO|IhcA>? MnjySG1UVw>? NF3DOIpKSzVyPUCuNVIzyrFyLkCwOEDPxE1? MUeyOVk1PDV4Nh?=
493H M4XQT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fMblczKGh? NHnycJBFVVOR NVTYOY9tUUN3ME2wMlA1P8LzMD6wNFkh|ryP MWeyOVk1PDV4Nh?=
716H M2r1fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1Pk[lczKGh? MXzEUXNQ NGT4[2lKSzVyPUCuNlEzyrFyLkCzOEDPxE1? MWGyOVk1PDV4Nh?=
148I M2rnZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PrTVczKGh? NInCSmpFVVOR MX\JR|UxRTBwMki0xtExNjB|NTFOwG0> MV2yOVk1PDV4Nh?=
98Sc NV:0cYk2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLUO|IhcA>? M1LRZ2ROW09? NHOxSZdKSzVyPUCuNVE2yrFyLkCwOEDPxE1? MlLGNlU6PDR3Nk[=
89R MoWxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2T2SFczKGh? NFnpN2FFVVOR NYLDcJVkUUN3ME2wMlEzPsLzMD6wNFMh|ryP NHK2dJIzPTl2NEW2Oi=>
494L M4PYWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGHXRW84OiCq MkfSSG1UVw>? NILBTFhKSzVyPUCuN|E4yrFyLkCxNkDPxE1? NULicZkyOjV7NES1OlY>
493L M1\YbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVjLTVlmPzJiaB?= M3jvNWROW09? NIX1cYFKSzVyPUCuNFUxyrFyLkCxNUDPxE1? M4XZO|I2QTR2NU[2
148L M2Pifmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjOO|IhcA>? MYHEUXNQ MVTJR|UxRTBwMUS2xtExNjBzNzFOwG0> Mkm4NlU6PDR3Nk[=
98L M2XNdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHP6XGw4OiCq Mm\ESG1UVw>? NGj2WFNKSzVyPUCuN|A6yrFyLkCyPUDPxE1? M2TCSlI2QTR2NU[2
OS17 MkLES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX[3NkBp NITObW9FVVOR M3nVR2lEPTB;MD6wO|nDuTBwMECzJO69VQ>? MWmyOVk1PDV4Nh?=
OS9 MlHlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\wR5I4OiCq NEH5O|dFVVOR M1viUGlEPTB;MD60NFbDuTBwMEK4JO69VQ>? NGfXOY4zPTl2NEW2Oi=>
MG63 NXrPWnlDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUe3NkBp NXvGVGduTE2VTx?= NX3lcpB5UUN3ME2wMlEyPMLzMD6wNlUh|ryP NYG2ZZFZOjV7NES1OlY>
SAOS2 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUC3NkBp NVjt[4RkTE2VTx?= Ml7RTWM2OD1yLkKxO:KyOC5yMEOg{txO MXeyOVk1PDV4Nh?=
U2OS M3LWOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXEO|IhcA>? M4TGVmROW09? MV7JR|UxRTBwMUm4xtExNjByODFOwG0> MWCyOVk1PDV4Nh?=
SJSA-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH;q[GE4OiCq Mm\ZSG1UVw>? M{XGOWlEPTB;MD6xNFDDuTBwMEGwJO69VQ>? MYeyOVk1PDV4Nh?=
494H MX\BdI9xfG:|aYOgRZN{[Xl? Mom2NE4zPS9yLkWvNU4xKM7:TR?= M{fvZlI1KGh? NEjI[nNFVVOR NF7PV2NqdmO{ZXHz[ZMhdGW4ZXzzJI9nKGOuZXH2[YQh[2G|cHHz[U0{yqB? MkC2NlU6PDR3Nk[=
148I MoDrRZBweHSxc3nzJGF{e2G7 M{P3NVAvOjVxMD61M|EvOCEQvF2= NYXx[HZWOjRiaB?= MWTEUXNQ NX3NXGUzcW6lcnXhd4V{KGyndnXsd{Bw\iClbHXheoVlKGOjc4Dhd4UuO8Li M4\scFI2QTR2NU[2
OS17 M37sb2Fxd3C2b4Ppd{BCe3OjeR?= NWnqOVA5OC5{NT:wMlUwOS5yIN88US=> NVTIOnR[OjRiaB?= NEG4bIlFVVOR NF31SJVqdmO{ZXHz[ZMhdGW4ZXzzJI9nKGOuZXH2[YQh[2G|cHHz[U0{yqB? NX7mPVZGOjV7NES1OlY>
494H MVTBdI9xfG:|aYOgRZN{[Xl? M33XRVHjiIoQvF2= M3;MdFQ5KGh? NULvOIhTTE2VTx?= MUnpcoR2[2W|IHPlcIwh[XCxcITvd4l{KHOrZ37p[olk[W62bIm= M3PkNVI2QTR2NU[2
148I MUDBdI9xfG:|aYOgRZN{[Xl? NGjPclYy6oDLzszN NGn4[Iw1QCCq MkfqSG1UVw>? MYfpcoR2[2W|IHPlcIwh[XCxcITvd4l{KHOrZ37p[olk[W62bIm= NWPUdHA5OjV7NES1OlY>
OS17 NHG5[3VCeG:ydH;zbZMhSXO|YYm= NGLtc4ky6oDLzszN MoDCOFghcA>? NF3udFRFVVOR NUfie3ZwcW6mdXPld{Bk\WyuIHHwc5B1d3OrczDzbYdvcW[rY3HueIx6 Mk\QNlU6PDR3Nk[=
MOLM13 NFG3VGhCeG:ydH;zbZMhSXO|YYm= M3nEeVI2OCCwTR?= M4jq[|Q5KGh? M2q3RWROW09? NVPVZZFVcW6mdXPld{B{cWewaX\pZ4FvfGy7IHHwc5B1d3OrczDjc5Rz\WG2bXXueEB4cXSqIIH1bZpienSrbnni NW\3cplxOjVyNUO4NlU>
MV4-11  NYH2ZYRnSXCxcITvd4l{KEG|c3H5 MVGyOVAhdk1? NYHOcGhKPDhiaB?= NU\3dYY4TE2VTx?= MojMbY5lfWOnczDzbYdvcW[rY3HueIx6KGGyb4D0c5NqeyClb4Ty[YF1dWWwdDD3bZRpKHG3aYrhdpRqdmmk MmXSNlUxPTN6MkW=
MOLM13 NGfaS4VHfW6ldHnvckBCe3OjeR?= NVHGNGJuOjVyIH7N MX:yOEBp MVXEUXNQ NE\Rc5lmdmijbnPld{ByfWm8YYL0bY5q[i2rbnT1Z4VlKG2xcnWgdFIyNCCESV2sJIFv\CClbHXheoVlKFCDUmC= NIryXVkzPTB3M{iyOS=>
MV4-11  NVXrdZYxTnWwY4Tpc44hSXO|YYm= NG\ke5QzPTBibl2= M2\LeFI1KGh? MnPLSG1UVw>? MUnlcohidmOnczDxeYl7[XK2aX7pZk1qdmS3Y3XkJI1wemVicEKxMEBDUU1uIHHu[EBkdGWjdnXkJHBCWlB? MVKyOVA2Ozh{NR?=
MOLM13 MXvBdI9xfG:|aYOgRZN{[Xl? NXPxfnN5OjVyIH7N M1zMclQ5KGh? NVnEPGpOTE2VTx?= M1rVT4lv\HWlZYOgd4lodmmoaXPhcpRtgSCjcH;weI9{cXNiY3;0doVifG2nboSge4l1cCCyb37heIlvcWJ? NF7QTWwzPTB3M{iyOS=>
MV4-11  M4O4cmFxd3C2b4Ppd{BCe3OjeR?= Ml3DNlUxKG6P MYG0PEBp NF\QVFJFVVOR NXzP[3dncW6mdXPld{B{cWewaX\pZ4FvfGy7IHHwc5B1d3OrczDjc5Rz\WG2bXXueEB4cXSqIIDvcoF1cW6rYh?= NWCwSVlIOjVyNUO4NlU>
Hela M2W1U2NmdGxiVnnhZoltcXS7IFHzd4F6 MVqwMVUxOCCwTR?= M2LQe|czKGh? M{mzWWROW09? NVTiWlV{\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy MV6yOVAxQTJ7NR?=
HBL-1 MYjD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NETENVIxNTVyMDDuUS=> MWC3NkBp MWDEUXNQ M1ewWIRm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= M1npbVI2ODB7Mkm1
HLY-1 NHnaTZBE\WyuIG\pZYJqdGm2eTDBd5NigQ>? M1nCRVAuPTByIH7N NUnJbHFtPzJiaB?= M1jSS2ROW09? NYP5UmRp\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy NIDST4EzPTByOUK5OS=>
OCI-Ly3 NGrweoJE\WyuIG\pZYJqdGm2eTDBd5NigQ>? MVywMVUxOCCwTR?= NH;wR2Q4OiCq MoruSG1UVw>? NIf2dWVl\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= NFn4dXczPTByOUK5OS=>
OCI-Ly10 NVewT41tS2WubDDWbYFjcWyrdImgRZN{[Xl? MU[wMVUxOCCwTR?= Mn;1O|IhcA>? MnvmSG1UVw>? NVzJT45F\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy MVGyOVAxQTJ7NR?=
SU-DHL-4 M4fmfGNmdGxiVnnhZoltcXS7IFHzd4F6 MknrNE02ODBibl2= MV23NkBp M4THc2ROW09? MkLS[IVkemWjc3XzJINmdGxidnnhZoltcXS7IHnuJIEh\G:|ZT3k[ZBmdmSnboSgcYFvdmW{ MonyNlUxODl{OUW=
SU-DHL-5 MlXKR4VtdCCYaXHibYxqfHliQYPzZZk> NEG0VlExNTVyMDDuUS=> NYTPNoM{PzJiaB?= Mn3ISG1UVw>? M{XGS4Rm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= MWmyOVAxQTJ7NR?=
SU-DHL-6 MlfuR4VtdCCYaXHibYxqfHliQYPzZZk> M4rvS|AuPTByIH7N NWTLb3ZmPzJiaB?= NIHqbJlFVVOR NVPnOZdw\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy NEm5R3MzPTByOUK5OS=>
SU-DHL-10 NYrMNoNvS2WubDDWbYFjcWyrdImgRZN{[Xl? MVmwMVUxOCCwTR?= M1L3SVczKGh? NIG0PIdFVVOR NYTYXIJ5\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy MnjYNlUxODl{OUW=
RC-K8 MljwR4VtdCCYaXHibYxqfHliQYPzZZk> MXWwMVUxOCCwTR?= M133UFczKGh? MYPEUXNQ M{\tN4Rm[3KnYYPld{Bk\WyuII\pZYJqdGm2eTDpckBiKGSxc3Wt[IVx\W6mZX70JI1idm6nch?= M1;aVVI2ODB7Mkm1
OCI-Ly8 MWfD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NWjR[|JMOC13MECgcm0> MYK3NkBp MW\EUXNQ MUnk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHliaX6gZUBld3OnLXTldIVv\GWwdDDtZY5v\XJ? MUWyOVAxQTJ7NR?=
OCL-Ly18 M{S5eGNmdGxiVnnhZoltcXS7IFHzd4F6 MkTHNE02ODBibl2= M1jKbVczKGh? NX\VPXRbTE2VTx?= NGnYWYNl\WO{ZXHz[ZMh[2WubDD2bYFjcWyrdImgbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= Mm\vNlUxODl{OUW=
OCI-Ly3 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DTTFE4Oi9{NUCvOVAxKG6P MnjLNk84KGR? MUTEUXNQ NHjme4pqdmS3Y3XzJINmdGxvY4njcIUh[XK{ZYP0JIF1KHO3Yj3HNUB4cXSqIH3pcolu[WxiY3XscEBl\WG2aNMg NIjGOnAzPTByOUK5OS=>
OCI-Ly8 NX\tcpp1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmroNVczNzJ3MD:1NFAhdk1? NFfIR4czNzdiZB?= NXHETFk{TE2VTx?= NIDveHRqdmS3Y3XzJINmdGxvY4njcIUh[XK{ZYP0JIF1KHO3Yj3HNUB4cXSqIH3pcolu[WxiY3XscEBl\WG2aNMg M3faOlI2ODB7Mkm1
SU-DHL-4 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3NcodiOTd{L{K1NE82ODBibl2= M{fYO|IwPyCm M{W5fmROW09? NUizZ|JJcW6mdXPld{Bk\WyuLXP5Z4xmKGG{cnXzeEBifCC|dXKtS|Ehf2m2aDDtbY5qdWGuIHPlcIwh\GWjdHlCpC=> NGrseoUzPTByOUK5OS=>
SU-DHL-10 NYTCTlhsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\xZWkyPzJxMkWwM|UxOCCwTR?= NH\VSVgzNzdiZB?= NGHmfJJFVVOR NFW3fVhqdmS3Y3XzJINmdGxvY4njcIUh[XK{ZYP0JIF1KHO3Yj3HNUB4cXSqIH3pcolu[WxiY3XscEBl\WG2aNMg MX:yOVAxQTJ7NR?=
OCI-Ly3 NWHybGNsSXCxcITvd4l{KEG|c3H5 MYmxO|IwOjVyIH7N NUjEeWNlP2R? MYPEUXNQ MV3pcoNz\WG|ZYOgZ4F{eGG|ZT2zM|ch[WO2aY\peJnDqHOrZ37p[olk[W62bIm= NWDhVWtsOjVyMEmyPVU>
OCI-Ly8 M4TWfGFxd3C2b4Ppd{BCe3OjeR?= MUOxO|IwOjVyIH7N M3naZ|dl MoPuSG1UVw>? NVLOPVdEcW6lcnXhd4V{KGOjc4Dhd4UuOy95IHHjeIl3cXS7wrDzbYdvcW[rY3HueIx6 NV7WVZlpOjVyMEmyPVU>
SU-DHL-4 NF\RRmFCeG:ydH;zbZMhSXO|YYm= MlXENVczNzJ3MDDuUS=> M1TiOVdl NIXne2xFVVOR NFy2[lBqdmO{ZXHz[ZMh[2G|cHHz[U0{NzdiYXP0bZZqfHoEoIPp[45q\mmlYX70cJk> NFLtVFIzPTByOUK5OS=>
SU-DHL-10 NXXTc4M{SXCxcITvd4l{KEG|c3H5 MnWyNVczNzJ3MDDuUS=> NXTSZXdMP2R? MUHEUXNQ NF3kRplqdmO{ZXHz[ZMh[2G|cHHz[U0{NzdiYXP0bZZqfHoEoIPp[45q\mmlYX70cJk> NWn6fodEOjVyMEmyPVU>

... Click to View More Cell Line Experimental Data

体内研究 (+)-JQ1(50 mg/kg)处理携带NMC 797移植瘤的小鼠,抑制肿瘤生长。(+)-JQ1(50 mg/kg) 抹消掉携带NMC 797移植瘤的小鼠的NUT核斑点, 与竞争性结合到核染色质相一致。(+)-JQ1(50 mg/kg)处理NMC 797移植瘤, 显著诱导(31级)角蛋白表达。(+)-JQ1(50 mg/kg)处理携带NMC移植瘤的小鼠模型,促进分化,肿瘤衰退,延长寿命。[1](+)-JQ1(50 mg/kg)处理静脉注射MM.1S-luc+细胞,携带原位移植瘤的SCID米色小鼠,与对照组动物相比,显著延长小鼠的总生存期。[2](+)-JQ1(50 mg/kg,腹腔注射)处理携带Raji移植瘤的小鼠,显著提高小鼠寿命。[3]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:

[1]

+ 展开
  • Cell lines: MC 11060细胞
  • Concentrations: ~500 nM
  • Incubation Time: 48小时
  • Method:

    细胞按每孔500个接种在白色, 384孔微孔板,孔中含总体为50 μL的培养基。797, TT和TE10细胞生长在含1% Penicillin/Streptomycin 和 10% FBS的DMEM培养基上。Per403细胞生长在含1 % Penicillin/Streptomycin和20% FBS的DMEM 培养基上。病患衍生的NMC 11060细胞生长在含10% FBS 和1% Penicillin/Streptomycin的RPMI培养基上。通过自动化针转移机将(+)-JQ1置于微量检测板上。使细胞裂解,通过增殖试验测评孔中的总ATP含量。根据剂量,重复测量分析,通过逻辑回归(GraphPad Prism)计算IC50。


    (Only for Reference)
动物实验:

[1]

+ 展开
  • Animal Models: 携带NMC 797移植瘤的小鼠
  • Formulation: 5% DMSO溶于5% 葡萄糖
  • Dosages: 50 mg/kg
  • Administration: 腹腔注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 91 mg/mL warmed (199.12 mM)
Ethanol 91 mg/mL (199.12 mM)
Water Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
5mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 456.99
化学式

C23H25ClN4O2S

CAS号 1268524-70-4
稳定性 powder
in solvent
别名 N/A

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

常见问题及建议解决方法

  • 问题 1:

    How can I reconstitute the compound for in vivo injection?

  • 回答:

    JQ1 does not dissolve in water/PBS. The vehicle we recommend is 2% DMSO+30% PEG 300+5% Tween 80+ddH2O. The compound can be dissolved in the vehicle at 5mg/ml and you can use it for IV injection.

Epigenetic Reader Domain Signaling Pathway Map

Epigenetic Reader Domain Inhibitors with Unique Features

Tags: 购买(+)-JQ1 | (+)-JQ1供应商 | 采购(+)-JQ1 | (+)-JQ1价格 | (+)-JQ1生产 | 订购(+)-JQ1 | (+)-JQ1代理商
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID