Mitomycin C

For research use only. Not for use in humans.

目录号:S8146

Mitomycin C Chemical Structure

CAS No. 50-07-7

Mitomycin C 是一种抗肿瘤类抗生素,通过抑制DNA合成发挥作用,用于治疗各种癌症。Mitomycin C 可诱导半胱氨酸蛋白酶依赖性和Fas/CD95非依赖性的 apoptosis 已取得危险化学品经营许可

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客户使用Selleck生产的Mitomycin C发表文献29篇:

产品安全说明书

Antineoplastic and Immunosuppressive Antibiotics抑制剂选择性比较

生物活性

产品描述 Mitomycin C 是一种抗肿瘤类抗生素,通过抑制DNA合成发挥作用,用于治疗各种癌症。Mitomycin C 可诱导半胱氨酸蛋白酶依赖性和Fas/CD95非依赖性的 apoptosis
靶点
DNA synthesis [1]
体外研究

Mitomycin C,通过诱导DNA链间交联,物理性阻断DNA复制,重组和RNA转录。[1] Mitomycin C增强TRAIL-诱导的HCT116 (p53-/-)结肠癌细胞的凋亡,并通过死亡受体不依赖于JNK的上调使耐TRAIL的结肠癌细胞HT-29对细胞因子敏感。[2]在不同的人癌症细胞系中,如OVCAR-5 (卵巢),HT-29 (结肠),SK-N-MC (成神经细胞瘤),HEP-2 (肝脏),COLO-205 (结肠),NIH-OVCAR-3 (卵巢)和A-549 (肺),Mitomycin C表现出细胞毒性。[3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human NTERA-S-cl-D1 cell M4XhNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF\EOmlKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlIy\S1yNTFOwG0> M{exV3NCVkeHUh?=
human MOLT-4 cell NGTWS2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1XyXmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPWVvMEWg{txO MmnVV2FPT0WU
human J82 cell MmHWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEfSN3pKdmirYnn0bY9vKG:oIHj1cYFvKEp6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVE6KG6P NGSzeldUSU6JRWK=
human 697 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVjJcohq[mm2aX;uJI9nKGi3bXHuJFY6PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G778{MJGlEPTB;MD6xNlghdk1? MWjTRW5ITVJ?
human KYSE-510 cell M4XxXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUTJcohq[mm2aX;uJI9nKGi3bXHuJGt[W0VvNUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDlibl2= MVnTRW5ITVJ?
human NCI-H2170 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn36TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxO|Ah[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF3MTDuUS=> NGq2ZZZUSU6JRWK=
human BE-13 cell NIqwXHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4XyZWlvcGmkaYTpc44hd2ZiaIXtZY4hSkVvMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE3PyCwTR?= MlfSV2FPT0WU
human LC-2-ad cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVL1SphsUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2yMYFlKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5{NEmgcm0> NXL0PY9ZW0GQR1XS
human IMR-5 cell Mn7ZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NW[wUnFOUW6qaXLpeIlwdiCxZjDoeY1idiCLTWKtOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzB6IH7N MVjTRW5ITVJ?
human EW-16 cell NVS2XYR1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXizOIJRUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzFibl2= M4fWVXNCVkeHUh?=
human MC-IXC cell M1rZVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoLxTY5pcWKrdHnvckBw\iCqdX3hckBOSy2LWFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY{QCEQvF2= NWHQbYlQW0GQR1XS
human SW872 cell MlHGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXPnXXZkUW6qaXLpeIlwdiCxZjDoeY1idiCVV{i3NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjd4IN88US=> NEDEUG1USU6JRWK=
human NCI-H2228 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkKyPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPzl4IN88US=> NYC3dYdmW0GQR1XS
K562 leukemia cells MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWLJckB3cXS{bzDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4SgT|U3OiCuZYXr[Y1q[SClZXzsd{whUUN3ME2xJI5O M4\0dVEzPjl7M{i2
human NALM-6 cell M4nr[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWDUN5BHUW6qaXLpeIlwdiCxZjDoeY1idiCQQVzNMVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB5IH7N NULsfFNSW0GQR1XS
AA8 cells MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoL0OEBp M2PreWlvcGmkaYTvdpkh[WO2aY\peJkhd2ZiY3;tdI92dmRiZn;yJGFCQCClZXzsd{B1dyC{ZXT1Z4Uh[2WubDDk[Y5{cXS7IHL5JFUxLSBqZYjwc5Nm\CC2bzDjc41xd3WwZDDmc5IhPCCqb4Xyd{k> MnfUNlkxQTd2MR?=
human ES4 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnWyTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkW2JI5O NHPGNItUSU6JRWK=
human KE-37 cell M2WzNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{juVGlvcGmkaYTpc44hd2ZiaIXtZY4hU0VvM{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlY1KG6P M4GxTXNCVkeHUh?=
human IST-MEL1 cell Mnn1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUfTUHBjUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwNkigcm0> M4PMTnNCVkeHUh?=
human ES8 cell NVvIOmFVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2P0UmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63NUBvVQ>? M4jYUXNCVkeHUh?=
human MV-4-11 cell M2LqeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1LQRmlvcGmkaYTpc44hd2ZiaIXtZY4hVVZvND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPzNibl2= M4[4PXNCVkeHUh?=
human 639-V cell Mon2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2nkO2lvcGmkaYTpc44hd2ZiaIXtZY4hPjN7LW[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlc3KG6P M1rRXnNCVkeHUh?=
human OCI-AML2 cell NWLhdZpzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{THdWlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh7IH7N MorxV2FPT0WU
human SK-LU-1 cell MmPYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mln2TY5pcWKrdHnvckBw\iCqdX3hckBUUy2OVT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4zOiCwTR?= NFvpUphUSU6JRWK=
human PSN1 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIPZZZZKdmirYnn0bY9vKG:oIHj1cYFvKFCVTkGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlU2KG6P Mnu5V2FPT0WU
human REH cell NFrrXm5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2\QcmlvcGmkaYTpc44hd2ZiaIXtZY4hWkWKIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj61OUBvVQ>? NID3[ZRUSU6JRWK=
human SBC-5 cell NG\EdmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUjJcohq[mm2aX;uJI9nKGi3bXHuJHNDSy13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj61PUBvVQ>? NX;rb2xMW0GQR1XS
human HT-3 cell MnHrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkXhTY5pcWKrdHnvckBw\iCqdX3hckBJXC1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj65N{BvVQ>? NH[1PJhUSU6JRWK=
human SIG-M5 cell M3jHd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWTBfHhNUW6qaXLpeIlwdiCxZjDoeY1idiCVSVetUVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{NjV{IH7N MoSyV2FPT0WU
human ES7 cell M2i4U2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmX3TY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lk[1JI5O NWXIXHBvW0GQR1XS
human CHP-212 cell NEW1dpNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIrUWVZKdmirYnn0bY9vKG:oIHj1cYFvKEOKUD2yNVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjN5IH7N MkHCV2FPT0WU
human P12-ICHIKAWA cell M36z[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXLJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwN{mgcm0> MVfTRW5ITVJ?
human HUTU-80 cell NIfUc4NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYHKO3JIUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC56MzDuUS=> Ml7RV2FPT0WU
human P30-OHK cell Ml7LS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{P2Z2lvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQDRibl2= MnTyV2FPT0WU
human NCI-H1651 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI\1d|FKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY2OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwOUmgcm0> MoXIV2FPT0WU
Chinese hamster V-C8 mutant cells NESxfmxEgXSxdH;4bYPDqGG|c3H5 MmXnN{Bl[Xm| NWnvVI5nS3m2b4TvfIlkcXS7IHHnZYlve3RiQmLDRVIu\GWoaXPp[Y51KEOqaX7ld4UhcGGvc4TldkBXNUN6IH31eIFvfCClZXzsd{Bi\nSncjCzJIRigXNiYomgW3NVOSClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13IH7N MYixPFUxPTJ6NB?=
human COR-L279 cell NF7yNXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVvReIpPUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSgcm0> NW\tdYE2W0GQR1XS
human CMK cell M3\4N2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1\qbmlvcGmkaYTpc44hd2ZiaIXtZY4hS02NIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT64N{BvVQ>? M3j5VHNCVkeHUh?=
human MHH-CALL-2 cell NWPufXZ{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2fsdWlvcGmkaYTpc44hd2ZiaIXtZY4hVUiKLVPBUGwuOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZwME[gcm0> MlXKV2FPT0WU
human BV-173 cell MkHRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJGJXNTF5MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNFchdk1? MnnuV2FPT0WU
human NCI-H209 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1zHfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjF5IH7N MUfTRW5ITVJ?
human NCI-H460 cell M1GxNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok41PSCwTR?= MlrLV2FPT0WU
human DU-145 cell NXvMfItpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGfxNmhKdmirYnn0bY9vKG:oIHj1cYFvKESXLUG0OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPTJibl2= NWnkfJN[W0GQR1XS
SW480 colon cancer cell NWfrVXc2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoC1TY4hfmm2cn:gbY5pcWKrdHnvckBw\iCVV{S4NEBkd2yxbjDjZY5k\XJiY3XscEBtcW6nLDDJR|UxRTdibl2= MY[xPVIxOzR7
human 769-P cell MlqxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoD4TY5pcWKrdHnvckBw\iCqdX3hckA4PjlvUDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNVEhdk1? MX;TRW5ITVJ?
human ES1 cell M3HuZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\oSWlvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz6yPUBvVQ>? M3fyRnNCVkeHUh?=
human COLO-668 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnrITY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLU[2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPTVibl2= M3rnfXNCVkeHUh?=
human NKM-1 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnnOHZYUW6qaXLpeIlwdiCxZjDoeY1idiCQS12tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvQDNibl2= MXjTRW5ITVJ?
human ES3 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH3ZOlJKdmirYnn0bY9vKG:oIHj1cYFvKEWVMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuPFghdk1? NWX2cpFvW0GQR1XS
human SCC-3 cell MkDvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUnIfpFEUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1OtN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPTJibl2= MkmwV2FPT0WU
human SU-DHL-1 cell NHnINoNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVHJcohq[mm2aX;uJI9nKGi3bXHuJHNWNUSKTD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE43OSCwTR?= MoLIV2FPT0WU
human ML-2 cell NYfh[mVNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXvJcohq[mm2aX;uJI9nKGi3bXHuJG1NNTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD16Lke4JI5O NGrMbYRUSU6JRWK=
WiDr colon cancer cell NGPqO2lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYjSZVhMUW5idnn0do8hcW6qaXLpeIlwdiCxZjDXbWRzKGOxbH;uJINidmOncjDj[YxtKGyrbnWsJGlEPTB;MUCgcm0> M3TqSVE6OjB|NEm=
human SF295 cell NFPSdWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUj3[VRDUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK5OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjR6IH7N MWnTRW5ITVJ?
human EW-7 cell NIjRdWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4Lk[WlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlE1KG6P M{jYbnNCVkeHUh?=
human H4 cell MkfrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGjFO5JKdmirYnn0bY9vKG:oIHj1cYFvKEh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuOFQhdk1? MXPTRW5ITVJ?
human LB2241-RCC cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\5PGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF|LkG5JI5O MVfTRW5ITVJ?
human SR cell M{THOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXvYVotRUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlQ3KG6P MYPTRW5ITVJ?
human LB1047-RCC cell MkHzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFLPN4lKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMz62JI5O NHzYXVRUSU6JRWK=
human MCF7 cell M2\jO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjrSpU{UW6qaXLpeIlwdiCxZjDoeY1idiCPQ1[3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQSCwTR?= NV7sdGxkW0GQR1XS
human ESS-1 cell NEPpT|ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mo\FTY5pcWKrdHnvckBw\iCqdX3hckBGW1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlkzKG6P MkPwV2FPT0WU
human NCI-H2122 cell NE\jTXBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl4IH7N MV\TRW5ITVJ?
human 786-0 cell NVvyXmg2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4qzRWlvcGmkaYTpc44hd2ZiaIXtZY4hPzh4LUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE4xOSEQvF2= NFO1dFBUSU6JRWK=
human COLO-205 cell Mm\TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVzBU4NsUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVIxPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF2LkOzJO69VQ>? MoLPV2FPT0WU
human HAL-01 cell MmrZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX;ySHkxUW6qaXLpeIlwdiCxZjDoeY1idiCKQVytNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS55MzFOwG0> NFj2bo5USU6JRWK=
K562 leukemia cells MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoTCTY4hfmm2cn:gbY5pcWKrdH;yfUBi[3Srdnn0fUBi\2GrboP0JGs2PjJibHX1b4VucWFiY3XscJMhcW5idHjlJJBz\XOnbnPlJI9nKHCmMjygTWM2OD1zNT64JI5O MlXENVI3QTl|OE[=
human MHH-ES-1 cell NIqzcIVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnfLTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvRWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE3NjJ4IH7N M1Wz[HNCVkeHUh?=
human NUGC-3 cell NHLnfllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1f4OmlvcGmkaYTpc44hd2ZiaIXtZY4hVlWJQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvQTVibl2= NHrCWmFUSU6JRWK=
human RPMI-8402 cell M3ixXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn\1TY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLUi0NFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy5zMzDuUS=> MlXEV2FPT0WU
human ATN-1 cell M3nPPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3XyVWlvcGmkaYTpc44hd2ZiaIXtZY4hSVSQLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{4{QSCwTR?= NHPCdWJUSU6JRWK=
human NCI-H441 cell NGHmZ4ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUK5Uo9wUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ1OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF5Lk[gcm0> MlPvV2FPT0WU
human LB996-RCC cell M1nqUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWfvSGlzUW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT6gTWM2OD1zNz62PEBvVQ>? NGjLVJJUSU6JRWK=
human CAL-148 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHrHO3JKdmirYnn0bY9vKG:oIHj1cYFvKEODTD2xOFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy57MzDuUS=> MVvTRW5ITVJ?
human CTV-1 cell M4LZPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXn1OIo{UW6qaXLpeIlwdiCxZjDoeY1idiCFVG[tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjZ5IH7N M3TldnNCVkeHUh?=
human HOP-62 cell NXXRW29GT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUTJcohq[mm2aX;uJI9nKGi3bXHuJGhQWC14MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKwMlIhdk1? M3\EZ3NCVkeHUh?=
human CAKI-1 cell NGXheXJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3K5bWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GNST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvOzJibl2= M1ji[XNCVkeHUh?=
human PA-1 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGLuUVRKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{42OSCwTR?= NIrTUWRUSU6JRWK=
human HT-144 cell M{XsfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGhVNTF2NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlc2KG6P MXvTRW5ITVJ?
human LOUCY cell MkPkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHzuOnBKdmirYnn0bY9vKG:oIHj1cYFvKEyRVVPZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlYvOTlibl2= NXX0d5VLW0GQR1XS
human BPH-1 cell NXXiR5RuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYXDb5huUW6qaXLpeIlwdiCxZjDoeY1idiCEUFitNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI6Njlibl2= NXXITnhrW0GQR1XS
human LS-1034 cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3nQVGlvcGmkaYTpc44hd2ZiaIXtZY4hVFNvMUCzOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjF4IH7N MUnTRW5ITVJ?
human 23132-87 cell Ml3IS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4izemlvcGmkaYTpc44hd2ZiaIXtZY4hOjNzM{KtPFch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC53MzDuUS=> Mm\xV2FPT0WU
human BB30-HNC cell MoLES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV7UcGRpUW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNyLk[xJI5O NIC3RYJUSU6JRWK=
human CAL-51 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIrlWIRKdmirYnn0bY9vKG:oIHj1cYFvKEODTD21NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjh4IH7N NW\IZoFpW0GQR1XS
human ALL-PO cell NUK4NoRuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDlfWY3UW6qaXLpeIlwdiCxZjDoeY1idiCDTFytVG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC57ODDuUS=> NG\sPGVUSU6JRWK=
human 5637 cell Mk\ES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUHMSGNQUW6qaXLpeIlwdiCxZjDoeY1idiB3NkO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|EvQTNibl2= M2nWSnNCVkeHUh?=
MCF-7 cell NUfzT|QzTnWwY4Tpc44h[XO|YYm= NHLZdI9CdnSrdIXtc5IheG:2ZX7jfUBwdiCqdX3hckBjemWjc4SgUWNHNTdiY3XscEBtcW6nczygTWM2OD1|Mj6yJI5O MWixPVA3OTB7
human KYSE-150 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGPQeFdKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtNVUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwMEmgcm0> NVzGZ3dUW0GQR1XS
human RS4-11 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmfrTY5pcWKrdHnvckBw\iCqdX3hckBTWzRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOE45PiCwTR?= M2XiU3NCVkeHUh?=
human A3-KAW cell NILJXmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUjJcohq[mm2aX;uJI9nKGi3bXHuJGE{NUuDVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO0Mlk3KG6P NELUSJVUSU6JRWK=
human NCI-H719 cell MoPES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{G5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|UvOTJibl2= NFLKWFRUSU6JRWK=
human GI-1 cell MlHWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmDvTY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVYhdk1? Mm\jV2FPT0WU
human HEL cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVmzNIR6UW6qaXLpeIlwdiCxZjDoeY1idiCKRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU45KG6P NYrpXnI6W0GQR1XS
human TE-8 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;PPWZRUW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|UvQDZibl2= NHPxcFJUSU6JRWK=
human HT-29 cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX70fIxkUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2yPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjB{IH7N NU\JbGw{W0GQR1XS
human SW1783 cell M2\VWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3zEOmlvcGmkaYTpc44hd2ZiaIXtZY4hW1dzN{izJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvKEmFNUC9N|gvPThibl2= NXnkWlVHW0GQR1XS
human CGTH-W-1 cell M2\FXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHf6fVdKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwIFnDOVA:OzhwN{Sgcm0> MWHTRW5ITVJ?
human MEL-HO cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4nCdWlvcGmkaYTpc44hd2ZiaIXtZY4hVUWOLVjPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvPCCwTR?= M4TEfnNCVkeHUh?=
human SW620 cell MmXWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnfXTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ{MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5Mlc6KG6P NYHobJo2W0GQR1XS
Human Caki-1 Renal CellCarcinoma Cell NYfJdJVPTnWwY4Tpc44h[XO|YYm= MlntPVYhcA>? NInX[VZKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gZYdicW6|dDDIeY1idiCFYXvpMVEhWmWwYXygR4VtdEOjcnPpco9u[SCFZXzsJGxqdmW|IDjDSFcxMyliYYSgPVZ1cCCqb4XyMEBq[zVyPUSwJI5O MnHONVU4PDNzN{i=
human CH1 (ovarian) tumor cell NVXodlB6S3m2b4TvfIlkyqCjc4PhfS=> M2HNRXRp\SClb33wc5Vv\CC5YYOg[ZZidHWjdHXkJIZweiC2aHWgZ5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2gyKCixdnHybYFvMSC2dX3vdkBk\WyuIHzpcoV{NCCLQ{WwQVQxKG6P NGHNSIEyODZ7OES0OC=>
human HT-29 (colon) tumor cell NIWyVXdEgXSxdH;4bYPDqGG|c3H5 NGn6NppVcGViY3;tdI92dmRid3HzJIV3[Wy3YYTl[EBnd3JidHjlJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IDjjc4xwdilidIXtc5Ih[2WubDDsbY5meyxiSVO1NF01OCCwTR?= MYOxNFY6QDR2NB?=
human A549 cells NGXxSXNEgXSxdH;4bYPDqGG|c3H5 M4nDelQ5KGh? MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;NECgcm0> NIDveVQzPTJ3OUWxOS=>
human ME-180 cell MoLDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3nzWGlvcGmkaYTpc44hd2ZiaIXtZY4hVUVvMUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFAvOTFibl2= MorpV2FPT0WU
human CAL-27 cell NG[yPXBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M374TGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUK3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFEvOThibl2= NUe1VYdpW0GQR1XS
human A431 cell MnHUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUn3WWdEUW6qaXLpeIlwdiCxZjDoeY1idiCDNEOxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFMvPzdibl2= M1nCcHNCVkeHUh?=
human SW954 cell MkTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnvvTY5pcWKrdHnvckBw\iCqdX3hckBUXzl3NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS0MlkyKG6P Mn7WV2FPT0WU
human CAL-39 cell NWHzZVJ6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmfFTY5pcWKrdHnvckBw\iCqdX3hckBESUxvM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok41QSCwTR?= MljkV2FPT0WU
human LU-134-A cell MnrnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH62S4JKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwN{Kgcm0> NUDXOJpvW0GQR1XS
human DU-4475 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnPlTY5pcWKrdHnvckBw\iCqdX3hckBFXS12NEe1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPDdibl2= NWPyVI0{W0GQR1XS
P388 cells (P388/S) cells NYPkcYJ2TnWwY4Tpc44h[XO|YYm= MmHHSZZidHWjdHnvckBw\iCrbnjpZol1d3K7IHHjeIl3cXS7IHHnZYlve3RiZIL1[{B{\W6|aYTpeoUhWDN6ODDj[YxteyBqUEO4PE9UMSClZXzsd{whUUN3ME20PEBvVQ>? MnfxPFU1PDF6Mx?=
human DEL cell NFXobG1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWjZNnVjUW6qaXLpeIlwdiCxZjDoeY1idiCGRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PE4{QSCwTR?= MXrTRW5ITVJ?
human HGC-27 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEftc21KdmirYnn0bY9vKG:oIHj1cYFvKEiJQz2yO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ6NjJ7IH7N M1[2UnNCVkeHUh?=
human RH-1 cell M3jtbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4PpTGlvcGmkaYTpc44hd2ZiaIXtZY4hWkhvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS5MlU4KG6P M4K4UXNCVkeHUh?=
HL-60 cells MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3nHbmlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHige4F{KHO2dXTp[YQhcW5iaIXtZY4heHKxbYnlcI9kgXSrYzDs[ZVs\W2rYzCoTGwuPjBrIHPlcIx{NCCLQ{WwQVUxKG6P M2XtPFg4ODlzMUG=
human A2780 (ovarian) tumor cell NXXjeohzS3m2b4TvfIlkyqCjc4PhfS=> Mof6WIhmKGOxbYDveY5lKHejczDleoFtfWG2ZXSg[o9zKHSqZTDjfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBNlc5OCBqb4\hdolidilidIXtc5Ih[2WubDDsbY5meyxiSVO1NF02OCCwTR?= NX7RdotHOTB4OUi0OFQ>
human SK-MES-1 cell MmPGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{C1PGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTVXTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02OS5zMjDuUS=> MnvzV2FPT0WU
human MEL-JUSO cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX7Jcohq[mm2aX;uJI9nKGi3bXHuJG1GVC2MVWPPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVEvOjVibl2= NEnueoFUSU6JRWK=
human VA-ES-BJ cell NUPmRWVuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX7kfIFPUW6qaXLpeIlwdiCxZjDoeY1idiCYQT3FV{1DUiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTV{LkG2JI5O NWXQcmFQW0GQR1XS
human EW-13 cell MnXPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mnr3TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWyMlUyKG6P MVfTRW5ITVJ?
human Ca-Ski cell MoewS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGPmOFNKdmirYnn0bY9vKG:oIHj1cYFvKEOjLWPrbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU{Njd3IH7N Mnf4V2FPT0WU
human LXF-289 cell NIOzcIZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21OU4{PyCwTR?= MnvGV2FPT0WU
human IM-9 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHqwcGZKdmirYnn0bY9vKG:oIHj1cYFvKEmPLUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Ok4zOiCwTR?= MnTOV2FPT0WU
human HCE-4 cell NUfpUnJkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmDBTY5pcWKrdHnvckBw\iCqdX3hckBJS0VvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUW3Mlk1KG6P M2HwfHNCVkeHUh?=
human TYK-nu cell MkHYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3myOGlvcGmkaYTpc44hd2ZiaIXtZY4hXFmNLX71JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OVgvPzJibl2= M{LQPXNCVkeHUh?=
human NCI-H748 cell NV;kW2s4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlyxTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEe0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVU6NjV2IH7N M1v2dHNCVkeHUh?=
human ABC-1 cell NETRVYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGFDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NkGuNkBvVQ>? MYnTRW5ITVJ?
human CCRF-CEM cell NH\NbI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFXtWo1KdmirYnn0bY9vKG:oIHj1cYFvKEOFUl[tR2VOKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PjFwNkigcm0> NGfNZVBUSU6JRWK=
human EW-3 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFn4W|ZKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22NU46PSCwTR?= NI\YSHpUSU6JRWK=
human NCI-H2342 cell M1S2bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU\GfJhGUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFI{PDJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14Mj61NUBvVQ>? MlHDV2FPT0WU
human CNS cancer cells MmPHR5l1d3SxeHnjxsBie3OjeR?= MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDUnMh[2GwY3XyJINmdGy|LDDHTVUxRTZ2IH7N NHvNdZQyOTR5M{SxPC=>
human SK-PN-DW cell MlLJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlezTY5pcWKrdHnvckBw\iCqdX3hckBUUy2STj3EW{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVY{Njd4IH7N NXzjV3RvW0GQR1XS
human EB2 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUXxVI51UW6qaXLpeIlwdiCxZjDoeY1idiCHQkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhcWN3ME22OU4{PiCwTR?= MXfTRW5ITVJ?
human HUT78 cells NIexN4dRem:uaX\ldoF1cW:wIHHzd4F6 MkLYOFghcA>? MmTiRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVWS3PEBk\WyuczDh[pRmeiB2ODDodpMh[nlicnXzZZp2emmwIILl[JVkfGmxbjDhd5NigSxiaXO1NF03PiCwTR?= MXmyOlU1OTV6Nx?=
human colon cancer cell line HCT15 MYXDfZRwfG:6aXRCpIF{e2G7 MWS3NkBp NEn4VJpKdiC4aYTyc{BkgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubDDsbY5mKEiFVEG1JIFnfGW{IEeyJIhzKG:oIHTyeYch\Xiyb4P1doUh\GW2ZYLtbY5m\CCkeTD0bIUhW1KEIHHzd4F6NCCLQ{WwQVcxKG6P MWixOFk5ODZ5Mh?=
human HCT8 cells NH3xb5FEgXSxdH;4bYPDqGG|c3H5 M4TFc|czKGh? MorKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUizJI5O MYKxPFg1PTR2MR?=
human THP1 cells M3jyXmN6fG:2b4jpZ:Kh[XO|YYm= M1zPb|Q5KGh? M2rsZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHRJWDFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3ME2wMlEh|ryP MlzhNlUzPTl3MUW=
human PC3 cells M{jyXHBzd2yrZnXyZZRqd25iYYPzZZk> NYLLZ3FRPzJiaB?= MVnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhfHK7cHHuJIJtfWViZYjjcJV{cW:wIHHzd4F6NCCHQ{WwQVAvOTRizszN Mof3NVk3PzR7MEW=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PARP / Caspase 8 / Caspase 9 / Cleaved caspase-9 / Caspase 3 / Cleaved caspase-3; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h. After treatment, the cleavage of caspase 8, caspase 9, caspase 3, or PARP was detected by immunoblotting.

p-Akt / Akt / p-S6K / S6K / p-Jun / JNK; 

PubMed: 24901052     


LS174T cells were treated with mitomycin C (5 μg/ml) and/or rapamycin (2.5–10 μg/ml) for 24 h and p-Akt/Akt, p-S6K1/S6K1 and p-JNK/JNK were detected by immunoblotting. Actin was used to confirm the equal amount of proteins loaded in each lane.

Beclin 1 / p62 / ATG5; 

PubMed: 29142609     


(A) Beclin 1, p62 and ATG5 expression levels in T24 cells were measured by western blotting. 1 is the control, 2 MMC only, 3 MMC + 0.25 µmol/l, 4 MMC + 1 µmol/l and 5 MMC + 10 µmol/l 5-Aza-2′ deoxycitidine. GAPDH was used as an internal control. MMC: Mitomycin C

GRP78 / CHOP / Caspase-4 / Cleaved caspase-4; 

PubMed: 28553347     


(A) Dose-dependent effect of MMC on endoplasmic reticulum stress-associated proteins. Cells were treated with various concentrations of MMC (5, 10, 20 μg/mL) or phosphate buffered saline for 24 hours and immunoblot analysis was performed with antibodies specific for GRP78, Caspase-4, CHOP and GAPDH (control).

24901052 29142609 28553347
体内研究 作为浅表性膀胱肿瘤的临床首选,在大鼠膀胱肿瘤模型中,Mitomycin C (400 μM)显著预防膀胱肿瘤的生长。[4]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

动物实验:[4]
- 合并
  • Animal Models: Rat bladder tumor model
  • Dosages: 400 μM
  • Administration: Intravesical treatment
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 66 mg/mL (197.38 mM)
Water Insoluble
Ethanol Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 334.37
化学式

C15H18N4O5

CAS号 50-07-7
储存条件 粉状
溶于溶剂
别名 N/A

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02199327 Completed Drug: Mitomycin C|Drug: Interferon Alfa-2b Conjunctival Intraepithelial Neoplasia|Corneal Intraepithelial Neoplasia Coordinación de Investigación en Salud Mexico|Instituto Mexicano del Seguro Social|University of Guadalajara May 2014 Phase 4
NCT02015650 Terminated Drug: Cetuximab|Drug: Mitomycin-C/ 5-Fluorouracil Head and Neck Neoplasms Medical University Innsbruck April 2014 Phase 4

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操作手册

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID