PF-562271

For research use only. Not for use in humans.

目录号：S2890

CAS No. 717907-75-0

PF-562271是一种有效的，ATP竞争性的，可逆的FAK抑制剂，无细胞试验中IC50为1.5 nM，作用于FAK比作用于Pyk2选择性高10倍左右，比作用于其他蛋白激酶（除了一些CDKs）选择性高100倍以上。

规格

价格

库存

购买数量

10mM (1mL in DMSO)	RMB 2862.96	现货
5mg	RMB 1392.84	现货
10mg	RMB 2194.82	现货
50mg	RMB 5469.68	现货
100mg	RMB 7967.47	现货
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客户使用Selleck生产的PF-562271发表文献80篇：

Cancer Cell, 2019, 36(2):179-193

PubMed: 31378681 ( click the link to review the publication )

Cell, 2019, 36(2):179-193

PubMed: 28162770 ( click the link to review the publication )

J Clin Invest, 2020, 1;130(5):2422-2434

PubMed: 32250340 ( click the link to review the publication )

Nat Commun, 2020, 11(1):3282

PubMed: 32612176 ( click the link to review the publication )

ACS Appl Mater Interfaces, 2020, 15

PubMed: 32485098 ( click the link to review the publication )

Cell Rep, 2020, 30(6):1780-1797

PubMed: 32049010 ( click the link to review the publication )

Elife, 2020, 4;9:e50571

PubMed: 32017701 ( click the link to review the publication )

Cell Death Dis, 2020, 14;11(4):230

PubMed: 32286266 ( click the link to review the publication )

Aging (Albany NY), 2020, 7;12(9):8221-8240

PubMed: 32379705 ( click the link to review the publication )

Sci Rep, 2020, 10(1):419

PubMed: 31942012 ( click the link to review the publication )

J Biol Chem, 2020, jbc.RA120.012957

PubMed: 32934005 ( click the link to review the publication )

J Biol Chem, 2020, 12 pii: jbc

PubMed: 32280065 ( click the link to review the publication )

Cell Cycle, 2020, 14:1-13

PubMed: 32286145 ( click the link to review the publication )

Cells, 2020, 9(1)

PubMed: 31905606 ( click the link to review the publication )

Mol Cancer Ther, 2020, 19(2):637-649

PubMed: 31784455 ( click the link to review the publication )

Clin Cancer Res, 2019, 25(14):4552-4566

PubMed: 30979745 ( click the link to review the publication )

Sci Signal, 2019, 12(565)

PubMed: 30670633 ( click the link to review the publication )

Cell Death Dis, 2019, 10(10):738

PubMed: 31570694 ( click the link to review the publication )

J Biol Chem, 2019, 294(18):7221-7230

PubMed: 30846565 ( click the link to review the publication )

J Tissue Eng Regen Med, 2019, 13(4):625-636

PubMed: 30770650 ( click the link to review the publication )

J Cancer Res Clin Oncol, 2019, 145(6):1461-1469

PubMed: 31006845 ( click the link to review the publication )

Molecules, 2019, 24(10)

PubMed: 31109130 ( click the link to review the publication )

J Pharm Biomed Anal, 2019, 168:163-173

PubMed: 30807921 ( click the link to review the publication )

Mol Med Rep, 2019, 19(6):4753-4760

PubMed: 31059085 ( click the link to review the publication )
Zygote, 2019, 27(3):173-179

PubMed: 31171046 ( click the link to review the publication )

Cell Rep, 2018, 22(10):2784-2796

PubMed: 29514104 ( click the link to review the publication )

Oncogene, 2018, 37(22):2953-2966

PubMed: 29515233 ( click the link to review the publication )

Oncogene, 2018, 37(23):3166-3182

PubMed: 29545604 ( click the link to review the publication )

Cell Death Dis, 2018, 9(9):848

PubMed: 30154481 ( click the link to review the publication )

Cancer Sci, 2018, 109(12):3783-3793

PubMed: 30281878 ( click the link to review the publication )

J Am Heart Assoc, 2018, 7(18):e008604

PubMed: 30371220 ( click the link to review the publication )

J Cell Sci, 2018, 131(10)

PubMed: 29678906 ( click the link to review the publication )

Stem Cells Int, 2018, 2018:2190657

PubMed: 30275837 ( click the link to review the publication )

Int J Oncol, 2018, 53(4):1544-1556

PubMed: 30066854 ( click the link to review the publication )

Acta Pharmacol Sin, 2018, 10.1038/aps

PubMed: 29417941 ( click the link to review the publication )

Cell Cycle, 2018, 17(23):2577-2592

PubMed: 30488756 ( click the link to review the publication )

Oncol Rep, 2018, 40(4):2325-2333

PubMed: 30106432 ( click the link to review the publication )

Cancer Epidemiol Biomarkers Prev, 2018, 27(7):805-813

PubMed: 29654156 ( click the link to review the publication )

Sci Transl Med, 2017, 9(420)

PubMed: 29237758 ( click the link to review the publication )

Nat Commun, 2017, 8:14122

PubMed: 28098159 ( click the link to review the publication )

Mol Syst Biol, 2017, 13(1):905

PubMed: 28069687 ( click the link to review the publication )

Cancer Sci, 2017, 108(7):1347-1356

PubMed: 28406574 ( click the link to review the publication )

FEBS J, 2017, 284(17):2856-2869

PubMed: 28665039 ( click the link to review the publication )

Sci Rep, 2017, 7(1):4032

PubMed: 28642549 ( click the link to review the publication )

Mol Carcinog, 2017, 56(12):2558-2565

PubMed: 28667800 ( click the link to review the publication )

Cancer Manag Res, 2017, 9:879-889

PubMed: 29276408 ( click the link to review the publication )

Cell Signal, 2017, 38:1-9

PubMed: 28647573 ( click the link to review the publication )

Oncol Rep, 2017, 38(1):63-70

PubMed: 28560386 ( click the link to review the publication )
Onco Targets Ther, 2017, 10:5817-5826

PubMed: 29263678 ( click the link to review the publication )

Evid Based Complement Alternat Med, 2017, 2017:4535326

PubMed: 29234400 ( click the link to review the publication )

Mol Med Rep, 2017, 16(6):8937-8943

PubMed: 28990104 ( click the link to review the publication )

Oncotarget, 2017, 8(43):75102-75113

PubMed: 29088849 ( click the link to review the publication )

Biophys J, 2017, 113(7):1585-1598

PubMed: 28844472 ( click the link to review the publication )

Nat Cell Biol, 2016, 18(2):168-80

PubMed: 26689676 ( click the link to review the publication )

Nat Commun, 2016, 7:10354

PubMed: 26838601 ( click the link to review the publication )

Clin Cancer Res, 2016, 22(23):5851-5863

PubMed: 27220963 ( click the link to review the publication )

Cancer Res, 2016,

PubMed: 27216177 ( click the link to review the publication )

Cancer Lett, 2016, 376(1):188-96

PubMed: 26996299 ( click the link to review the publication )

Breast Cancer Res, 2016, 18(1):81

PubMed: 27495308 ( click the link to review the publication )

Oral Oncology, 2016, 10.1016/j.oraloncology.2016.05.010

PubMed: ( click the link to review the publication )

Sci Rep, 2016, 6:36214

PubMed: 27796369 ( click the link to review the publication )

J Biol Chem, 2016, 291(15):8140-9

PubMed: 26865633 ( click the link to review the publication )

Mol Pharmacol, 2016, 89(5):521-40

PubMed: 26895766 ( click the link to review the publication )

J Proteome Res, 2016, 15(12):4369-4386

PubMed: 27762562 ( click the link to review the publication )

Int J Biochem Cell Biol, 2016, 71:62-71

PubMed: 26693891 ( click the link to review the publication )

Oncotarget, 2016, 7(30):48093-48106

PubMed: 27344177 ( click the link to review the publication )

Sci Rep, 2016, 6:19261

PubMed: 26763933 ( click the link to review the publication )

Oncotarget, 2016, 7(29):45186-45198

PubMed: 27286256 ( click the link to review the publication )

Nat Cell Biol, 2015, 17(11):1412-21

PubMed: 26436690 ( click the link to review the publication )

Elife, 2015, 4

PubMed: 26274564 ( click the link to review the publication )

Oncogene, 2015, 34(40):5114-27

PubMed: 25639872 ( click the link to review the publication )

Cell Physiol Biochem, 2015, 37(2):515-26

PubMed: 26330161 ( click the link to review the publication )
J Biol Chem, 2015, 290(14):8677-92

PubMed: 25713079 ( click the link to review the publication )

Environ Toxicol Pharmacol, 2015, 39(1):114-24

PubMed: 25481308 ( click the link to review the publication )

Proc Natl Acad Sci U S A, 2015, 112(20):E2595-601

PubMed: 25941386 ( click the link to review the publication )

Oncotarget, 2015, 6(28):25755-69

PubMed: 26342198 ( click the link to review the publication )

Oncotarget, 2015, 6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

PLoS One, 2014, 9(2):e88587

PubMed: 24523919 ( click the link to review the publication )

Cancer Sci, 2013, 104(12):1618-25

PubMed: 24112719 ( click the link to review the publication )

Int J Clin Exp Pathol, 2013, 6(10):2082-91

PubMed: 24133586 ( click the link to review the publication )

产品安全说明书

FAK抑制剂选择性比较

生物活性

产品描述

靶点

FAK ^[1] (Cell-free assay)	PYK2 ^[1] (Cell-free assay)	CDK2/CyclinE ^[1] (Cell-free assay)	CDK3/CyclinE ^[1] (Cell-free assay)	CDK1/CyclinB ^[1] (Cell-free assay)	点击更多
1.5 nM	13 nM	30 nM	47 nM	58 nM	点击更多

体外研究

PF-562271会结合到ATP与FAK结合的部位,在激酶铰链区形成抑制剂与主链原子之间的两种氢键。PF-562271在测量FAK磷酸化可诱导的基于细胞的分析中效果很好，IC50为5 nM。PF-562271 (3.3 μM)导致PC3-M细胞周期停滞在G1期^[1]。在鸡胚绒毛尿囊膜实验中PF-562271 (1nM)阻断bFGF刺激的血管生成。 PF-262271 强有效的阻断血管生长但对血管渗漏没有明显影响^[2]。PF-562271 (250 nM)可以完全抑制整体A431 细胞侵入胶原蛋白中^[3]。

Cell Data

Cell Lines	Assay Type	Activity Description	PMID
MV-4-11	M1;ZTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYTJR\|UxRTBwMke2OkDPxE1?	MYTTRW5ITVJ?
SW982	M3nFRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1HBfmlEPTB;MD6zNlgzKM7:TR?=	MYLTRW5ITVJ?
KM12	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MXLJR\|UxRTBwM{i1OVch\|ryP	Ml\nV2FPT0WU
COLO-205	NFfTTI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2jxS2lEPTB;MD60PFY2QCEQvF2=	NECw[YxUSU6JRWK=
COLO-829	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWPJR\|UxRTBwN{WxO\|Yh\|ryP	NI\VTGxUSU6JRWK=
MG-63	MoqwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NX\Ufo5kUUN3ME2wMlgxPjN5IN88US=>	MoH6V2FPT0WU
IGROV-1	M3LsW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M332SWlEPTB;MD64NVA{QCEQvF2=	MoT6V2FPT0WU
NCI-H650	M{j2b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M2n5emlEPTB;MD64N\|E2PCEQvF2=	NEeybHNUSU6JRWK=
RT-112	NGOzNJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYTGOFMzUUN3ME2wMlk5PDZizszN	M1rIXnNCVkeHUh?=
BCPAP	NIS2ZXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWPrNpQ{UUN3ME2xMlAyOjh6IN88US=>	MkPmV2FPT0WU
ALL-PO	NHzH[pRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVzP[25xUUN3ME2xMlAyPTh2IN88US=>	NYL3[G5yW0GQR1XS
KYSE-270	MlHpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUjJR\|UxRTFwMES3NVQh\|ryP	M{T4[HNCVkeHUh?=
8305C	MoTxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NX\We2ppUUN3ME2xMlA6QTB2IN88US=>	M1L4NXNCVkeHUh?=
NCI-H810	MlviS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M13nVWlEPTB;MT6xNFc4PiEQvF2=	MXPTRW5ITVJ?
CAL-33	NVrVU3lTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4P1eGlEPTB;MT6xNlk{QCEQvF2=	NVGzSpR1W0GQR1XS
AN3-CA	NXXTRWc{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVrJR\|UxRTFwMkG4Olch\|ryP	M1KySXNCVkeHUh?=
NKM-1	Mn3BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4OxdWlEPTB;MT6yO\|UxPiEQvF2=	M{jkO3NCVkeHUh?=
BPH-1	Mnj0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NITxVWVKSzVyPUGuNlg4PjZizszN	NUiwZppsW0GQR1XS
MES-SA	M4rES2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mn3MTWM2OD1zLkOwOlgzKM7:TR?=	MXTTRW5ITVJ?
CAL-62	NHfaNpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NGLrW\|hKSzVyPUGuN\|E6ODlizszN	NUXaepd2W0GQR1XS
Detroit562	NULoZph1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NEXqOIhKSzVyPUGuN\|UzOjJizszN	MVjTRW5ITVJ?
KYSE-150	MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1e5dmlEPTB;MT6zOVI{PiEQvF2=	Ml25V2FPT0WU
SK-UT-1	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MYnJR\|UxRTFwNES2OFch\|ryP	M{TUOXNCVkeHUh?=
HUTU-80	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MoXuTWM2OD1zLkS0PFg3KM7:TR?=	NH;RZ2xUSU6JRWK=
SIG-M5	NFm2XnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWr6SoM6UUN3ME2xMlQ5Ozh5IN88US=>	MXHTRW5ITVJ?
AGS	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlvITWM2OD1zLkWyNVI1KM7:TR?=	NYTGdJlPW0GQR1XS
ST486	NEL4[XZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MW\JR\|UxRTFwNUOyO\|gh\|ryP	M1PHbHNCVkeHUh?=
HSC-2	NWT5[ZZkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4DjPWlEPTB;MT61N\|k2KM7:TR?=	NF7vVIdUSU6JRWK=
LCLC-103H	MlnRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mke3TWM2OD1zLkW1PFE5KM7:TR?=	M4O0VnNCVkeHUh?=
BC-1	NEjycmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2jZW2lEPTB;MT62NVY3PCEQvF2=	NWLoR4c2W0GQR1XS
CGTH-W-1	NIXIVFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWHJR\|UxRTFwNkG2O\|kh\|ryP	M2XKNXNCVkeHUh?=
MZ1-PC	MmHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmKyTWM2OD1zLk[yN\|EzKM7:TR?=	M1LBenNCVkeHUh?=
SW1710	M1PubWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MluwTWM2OD1zLk[yOlI5KM7:TR?=	NFrlSnJUSU6JRWK=
EW-13	MkTJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFv4SlNKSzVyPUGuOlM1PjZizszN	NYO2T2FUW0GQR1XS
TE-11	NIfkbJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NIfmd5dKSzVyPUGuOlM2OjJizszN	MWrTRW5ITVJ?
BHY	NHzzdW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVrJR\|UxRTFwNkW2OlMh\|ryP	M1;mfXNCVkeHUh?=
ML-2	NI[1WJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWTUTWUzUUN3ME2xMlY3QDB{IN88US=>	MXLTRW5ITVJ?
MEL-JUSO	M2noUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MXnJR\|UxRTFwN{K4PVEh\|ryP	M4DndHNCVkeHUh?=
U251	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M3XjRmlEPTB;MT63OFA{OSEQvF2=	NHLOToRUSU6JRWK=
MHH-ES-1	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M{jFXGlEPTB;MT63PVU3QCEQvF2=	MVXTRW5ITVJ?
CAL-85-1	NWe5N\|ZmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYrGU5psUUN3ME2xMlgxPDlizszN	NWX2N4xRW0GQR1XS
D-336MG	M3;FVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MWHJR\|UxRTFwOEW2NVQh\|ryP	NXHSSGpmW0GQR1XS
VA-ES-BJ	NYXKVGtvT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUXJR\|UxRTFwOUCzNVUh\|ryP	MVXTRW5ITVJ?
MDA-MB-468	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NYXSWIJxUUN3ME2xMlkyOjd{IN88US=>	M1G4[nNCVkeHUh?=
MEL-HO	NHflNmVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NHn6fnpKSzVyPUGuPVc6QTNizszN	M{fwdnNCVkeHUh?=
SW954	NF\n[o1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M365SGlEPTB;Mj6wNFE2OSEQvF2=	M4nPbnNCVkeHUh?=
LB831-BLC	Ml;WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M3S4V2lEPTB;Mj6wNFk5QCEQvF2=	M1TnO3NCVkeHUh?=
EW-16	Mm[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVLJR\|UxRTJwMEO5PFMh\|ryP	NVu3VWF7W0GQR1XS
NCI-H460	M3LJVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NUDyUJFCUUN3ME2yMlA1QDN7IN88US=>	NUTlbnJDW0GQR1XS
CHP-212	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlLBTWM2OD1{LkC5OVM6KM7:TR?=	MWXTRW5ITVJ?
MHH-NB-11	M3;mSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1;xeGlEPTB;Mj6xNlgyQCEQvF2=	MmPTV2FPT0WU
DU-4475	MkfLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmHPTWM2OD1{LkG0O\|U6KM7:TR?=	NY\HeFlKW0GQR1XS
ABC-1	MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NVTDUWxwUUN3ME2yMlI2OTl4IN88US=>	MmTnV2FPT0WU
LOUCY	MnPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4Cyb2lEPTB;Mj6yOlEzQCEQvF2=	MofxV2FPT0WU
LC-2-ad	NV7xenRzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MWTJR\|UxRTJwMk[5OlYh\|ryP	NF[zeYtUSU6JRWK=
ETK-1	NUTXeWxWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NWHnS4JsUUN3ME2yMlI5PDZizszN	MWDTRW5ITVJ?
KYSE-180	NWHvW5Z{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M{nGcGlEPTB;Mj6yPFg4PCEQvF2=	M4XEUnNCVkeHUh?=
HOP-92	M{nne2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MXvJR\|UxRTJwM{C2O\|Mh\|ryP	Ml3IV2FPT0WU
RCC10RGB	MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MYHJR\|UxRTJwM{K1NFch\|ryP	M3u0NXNCVkeHUh?=
KASUMI-1	M2f3PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NFTYcpJKSzVyPUKuN\|I5QCEQvF2=	NVHQcXFTW0GQR1XS
ACN	NVPiSWRuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVf3SmdpUUN3ME2yMlM1PzR3IN88US=>	NXnCdWpPW0GQR1XS
BxPC-3	MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Mof4TWM2OD1{LkO1OFM3KM7:TR?=	NFTWXnpUSU6JRWK=
MONO-MAC-6	NEPPfmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MkTlTWM2OD1{LkSxNlQ5KM7:TR?=	NIXoboFUSU6JRWK=
CAL-39	NEfrS4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVrJR\|UxRTJwNEG2Nlgh\|ryP	MVTTRW5ITVJ?
CMK	NFvXfotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVnKOo55UUN3ME2yMlQyPzl3IN88US=>	NWC5e3Z3W0GQR1XS
MFE-296	M2Todmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmXITWM2OD1{LkS3O\|kzKM7:TR?=	MoPyV2FPT0WU
DU-145	MlrmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYTJR\|UxRTJwNEmxNVgh\|ryP	NXzo[XR7W0GQR1XS
MDA-MB-231	MlrES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXqz[IU6UUN3ME2yMlQ6PTd{IN88US=>	NIHvVG1USU6JRWK=
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KYSE-510	Mm\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NX3zWFE4UUN3ME21Mlc6PThzIN88US=>	MX;TRW5ITVJ?
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OVCAR-3	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NW\kO4tJUUN3ME21Mlg5OjB4IN88US=>	NIfudmdUSU6JRWK=
LB1047-RCC	MlTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYLXTlA1UUN3ME21MlkxOTR6IN88US=>	NYfIcXZXW0GQR1XS
HEL	MkHJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mo\QTWM2OD14LkCyNVg5KM7:TR?=	NH3NTIdUSU6JRWK=
KARPAS-45	NWXCbJU1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUPJR\|UxRTZwMEO3PFch\|ryP	MmnNV2FPT0WU
NCI-H1304	MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlfiTWM2OD14LkGyOFk4KM7:TR?=	M1\ZPHNCVkeHUh?=
PC-3	M1LTemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmLCTWM2OD14LkGzNFczKM7:TR?=	M2f3[3NCVkeHUh?=
Calu-3	MmP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1zRPWlEPTB;Nj6xOFY5QSEQvF2=	NXTPbnFQW0GQR1XS
NCI-H1648	NEPvZXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NEDvTWVKSzVyPU[uNVUyPiEQvF2=	NVzsTlNzW0GQR1XS
HSC-3	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MkjNTWM2OD14LkG3N\|k3KM7:TR?=	NX6yc4kyW0GQR1XS
COLO-824	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXjoUYZmUUN3ME22MlI4QDZ6IN88US=>	M17H[HNCVkeHUh?=
COLO-680N	MlL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NG\IepNKSzVyPU[uN\|c3OzhizszN	MlvLV2FPT0WU
SK-NEP-1	NHj3ToVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYTPXHBoUUN3ME22MlQxOzZizszN	M4TaO3NCVkeHUh?=
SCC-25	NXPuZ3lRT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYDJR\|UxRTZwNEK0PVMh\|ryP	M1rOUHNCVkeHUh?=
SF295	M3TWWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnTyTWM2OD14LkS0PVgh\|ryP	MnfCV2FPT0WU
no-10	NVTpd\|hXT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NFTIN29KSzVyPU[uOFc5PCEQvF2=	MXvTRW5ITVJ?
NCI-H838	M4L2XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MlPRTWM2OD14LkWxO\|A{KM7:TR?=	NUf0W5FXW0GQR1XS
M059J	NGjHbGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVrJR\|UxRTZwNUW2NlUh\|ryP	NVnTN2FKW0GQR1XS
Calu-6	NED1fYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVPJR\|UxRTZwNkW0N\|Uh\|ryP	Mo\GV2FPT0WU
TE-12	NEnFNpRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXvxWJNMUUN3ME22MlczOzd5IN88US=>	M3foZnNCVkeHUh?=
639-V	M4Lje2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MV;JR\|UxRTZwN{WxNlch\|ryP	NGnFWHFUSU6JRWK=
ESS-1	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NI\EfG5KSzVyPU[uO\|YxPzJizszN	MmXHV2FPT0WU
C-4-II	NF7BSG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MonDTWM2OD14LkizNVE4KM7:TR?=	NWOzRm9VW0GQR1XS
23132-87	M1qxeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVjSXmxxUUN3ME22MlkxQTBzIN88US=>	NHfDPWdUSU6JRWK=
MEG-01	NEi2dFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NEfyVFNKSzVyPU[uPVM2PDZizszN	NVvXS2d{W0GQR1XS
GI-1	NVHVeWp3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M2rZUWlEPTB;Nj65OFM1QCEQvF2=	M4LvPXNCVkeHUh?=
NCI-H2347	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXLBfY15UUN3ME22Mlk1PzF3IN88US=>	MorlV2FPT0WU
MS-1	M{TPbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYjJR\|UxRTZwOUWxPVIh\|ryP	M{fw[XNCVkeHUh?=
SK-MEL-30	NHXmdmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MYLJR\|UxRTZwOU[zNVUh\|ryP	NIiyOXlUSU6JRWK=
YKG-1	Ml2zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NELxbZNKSzVyPUeuNFI3PzhizszN	MYXTRW5ITVJ?
HT-3	NHvObXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXXJR\|UxRTdwMEO0PUDPxE1?	MoLOV2FPT0WU
NCI-H2126	NVHhVoprT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVSy[W5pUUN3ME23MlA6PzlzIN88US=>	NH;seVZUSU6JRWK=
GI-ME-N	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MoG1TWM2OD15LkG2PVA3KM7:TR?=	NIe5UIdUSU6JRWK=
LB771-HNC	NWftPYlPT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHrCOHlKSzVyPUeuNVgxOzhizszN	NF3hUJBUSU6JRWK=
LCLC-97TM1	M4WxWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NHvQRZhKSzVyPUeuNlEzPzNizszN	NHXmc3pUSU6JRWK=
HO-1-N-1	M3;j[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mm\uTWM2OD15LkK0NFI1KM7:TR?=	MUPTRW5ITVJ?
HCC1143	NXm1WZlyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MWXJR\|UxRTdwM{e4PVgh\|ryP	NEPLcHNUSU6JRWK=
HuO9	NFnVTVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4XxTWlEPTB;Nz60PFc6PCEQvF2=	M1LneHNCVkeHUh?=
IST-SL2	MmW4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYTJR\|UxRTdwNUKyO\|Ih\|ryP	NWfhboRJW0GQR1XS
MLMA	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlXmTWM2OD15LkW0Olg6KM7:TR?=	MXPTRW5ITVJ?
22RV1	M1HMd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mk\STWM2OD15Lk[3PVc2KM7:TR?=	MVTTRW5ITVJ?
ONS-76	Mn;OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoSzTWM2OD15Lk[5OFE3KM7:TR?=	NV3xWY5OW0GQR1XS
ECC12	Ml\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYLJR\|UxRTdwN{K5NFEh\|ryP	MkfxV2FPT0WU
HT-1080	MonnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYSzeVB5UUN3ME23Mlc5PTV3IN88US=>	MVHTRW5ITVJ?
SF268	NIDEWIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3LJXmlEPTB;Nz64N\|U3KM7:TR?=	NELyXWpUSU6JRWK=
COLO-800	NXTlWI5ZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHfKR4ZKSzVyPUeuPVA3QDVizszN	MXvTRW5ITVJ?
BB30-HNC	NGDIb2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWrJR\|UxRTdwOUS1OVMh\|ryP	NXviOplwW0GQR1XS
CAKI-1	NFnFPG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NEPMO21KSzVyPUiuNFY2OjFizszN	MVHTRW5ITVJ?
GCIY	M2P1V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NF63d\|JKSzVyPUiuNlM4OTNizszN	M3HLW3NCVkeHUh?=
MKN28	NVPsSllzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MX7JR\|UxRThwMkS1PVgh\|ryP	M13WNnNCVkeHUh?=
IPC-298	NIjI[5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWPJR\|UxRThwMke3NFkh\|ryP	NH[0ZphUSU6JRWK=
NCI-H1650	MnfHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYTJR\|UxRThwMkmxPFUh\|ryP	NWe1[29[W0GQR1XS
KP-N-YS	MlT0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFiyR4hKSzVyPUiuNlk{ODhizszN	Mkn3V2FPT0WU
J82	Mn7PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnfiTWM2OD16LkO0NVI1KM7:TR?=	MYDTRW5ITVJ?
SK-HEP-1	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4HtbGlEPTB;OD6zOVczOyEQvF2=	NW\ReHg4W0GQR1XS
PANC-03-27	NGXZcm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M{jPTWlEPTB;OD6zOlkzKM7:TR?=	MmX1V2FPT0WU
KP-4	MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MmXzTWM2OD16LkSxPFU{KM7:TR?=	M3TjcHNCVkeHUh?=
RERF-LC-MS	NVraPGFtT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MmfPTWM2OD16LkS4OVk2KM7:TR?=	NHnzR\|BUSU6JRWK=
C-33-A	M32wNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Ml2yTWM2OD16Lk[xOVI6KM7:TR?=	NGXkeoVUSU6JRWK=
PA-1	M1zJPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Ml7LTWM2OD16Lk[2Olk1KM7:TR?=	NXu4cWhiW0GQR1XS
TE-5	MkPiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVfJR\|UxRThwN{CyPVYh\|ryP	MYDTRW5ITVJ?
MHH-PREB-1	MoixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NVfHOYxoUUN3ME24Mlc{OTB5IN88US=>	M3fMZnNCVkeHUh?=
C3A	NWq3UJpXT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NF\STmJKSzVyPUiuO\|Y2PjFizszN	MoDmV2FPT0WU
SK-OV-3	M4flSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NWLkR5l{UUN3ME24Mlc6Pzd{IN88US=>	NGTE[IhUSU6JRWK=
AM-38	MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Mn;vTWM2OD16LkiwOFM6KM7:TR?=	MlvVV2FPT0WU
LoVo	NG\MPZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3nkTWlEPTB;OD65OVU3PiEQvF2=	MVrTRW5ITVJ?
MKN45	NYfGbYxGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NEnLbXdKSzVyPUiuPVYxPjNizszN	M{HLc3NCVkeHUh?=
NH-12	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NUO1SYVuUUN3ME25MlAzPTR{IN88US=>	NV62eG41W0GQR1XS
CAMA-1	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MW\JR\|UxRTlwME[wNVIh\|ryP	M1X6d3NCVkeHUh?=
HT-29	Ml7OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NUH2emNjUUN3ME25MlEzOzd\|IN88US=>	MWjTRW5ITVJ?
DMS-273	NHzP[GFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWXJR\|UxRTlwMUK1JO69VQ>?	M1\mOXNCVkeHUh?=
NCI-H719	Ml3zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NUniZ2oyUUN3ME25MlE5OzlzIN88US=>	M{jLS3NCVkeHUh?=
SF539	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MYDJR\|UxRTlwMkGwPVgh\|ryP	NVzSfGNXW0GQR1XS
Daoy	M2[xXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MWfJR\|UxRTlwMkSxOFMh\|ryP	NILxVnpUSU6JRWK=
HCC70	MkftS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4XJT2lEPTB;OT6yO\|MxQSEQvF2=	MVTTRW5ITVJ?
MFH-ino	Mo\US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M370ZWlEPTB;OT6yPVAxPyEQvF2=	MYHTRW5ITVJ?
UACC-62	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NEf2[YNKSzVyPUmuN\|czQTdizszN	MVTTRW5ITVJ?
C2BBe1	MmC0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2[zUmlEPTB;OT6zPVY2OiEQvF2=	MWLTRW5ITVJ?
KNS-42	NGHjV4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1PjOGlEPTB;OT60N\|QxPyEQvF2=	MkTDV2FPT0WU
SK-LMS-1	Mn7KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Ml3LTWM2OD17Lke1OVM2KM7:TR?=	M3Ho[3NCVkeHUh?=
SK-CO-1	MmLtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NF64WIZKSzVyPUmuO\|YzOzVizszN	NGj6VI5USU6JRWK=
SN12C	M{XwWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MojsTWM2OD17Lke2PFA3KM7:TR?=	NGjmXG5USU6JRWK=
HTC-C3	NWTVSnF7T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYf3[nFWUUN3ME25Mlc4QTh2IN88US=>	MVPTRW5ITVJ?
OVCAR-4	M2TqO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M2PwXWlEPTB;OT64OFgzQCEQvF2=	MX7TRW5ITVJ?
CHP-126	Mor1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoOzTWM2OD17LkmzNlkh\|ryP	MkDYV2FPT0WU
NCI-H716	NXHWbYVWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NIfIO4NKSzVyPUmuPVM{OjJizszN	M3HSWHNCVkeHUh?=
U-698-M	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MXnJR\|UxRTlwOUm3JO69VQ>?	MUfTRW5ITVJ?
EFO-21	MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MXjJR\|UxRTFyLkCwPVMh\|ryP	NFqxT5NUSU6JRWK=
RXF393	NF7VfGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3vTXGlEPTB;MUCuNVM6OiEQvF2=	NImzWmtUSU6JRWK=
ChaGo-K-1	MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M{Dhd2lEPTB;MUCuNVc4PiEQvF2=	MW\TRW5ITVJ?
SJRH30	NV7z[WZ6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NUfodVdoUUN3ME2xNE4yQDR2IN88US=>	M{jZNHNCVkeHUh?=
LU-65	NIXydY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1nWZ2lEPTB;MUCuNlk1OyEQvF2=	NHLTUZNUSU6JRWK=
OS-RC-2	Ml7JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUPJR\|UxRTFyLkOyNlch\|ryP	NGD3VI9USU6JRWK=
YT	Mk\rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NUnGb\|dqUUN3ME2xNE41ODBzIN88US=>	NGnUVpdUSU6JRWK=
COLO-679	MnvNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NHK5UohKSzVyPUGwMlQzQDVizszN	M1rE[XNCVkeHUh?=
CAS-1	NF3vTldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnLXTWM2OD1zMD60OlA5KM7:TR?=	MoDNV2FPT0WU
NCI-H2052	MnS3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVjJR\|UxRTFyLkWxNFUh\|ryP	MXTTRW5ITVJ?
NCI-H2452	NE\rR2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MX;JR\|UxRTFyLk[xPFEh\|ryP	MkT5V2FPT0WU
SW13	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M{DMc2lEPTB;MUCuOlM4PCEQvF2=	NV\UXnc4W0GQR1XS
HuP-T4	M2LPO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NXjvV2J[UUN3ME2xNE44ODZ6IN88US=>	MmW2V2FPT0WU
UMC-11	NIm4cGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MYHJR\|UxRTFyLkmzO\|Mh\|ryP	NVL4cI52W0GQR1XS
EGI-1	NIK5bFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NEPEfnlKSzVyPUGwMlk1PTVizszN	NEjwbFZUSU6JRWK=
JiyoyeP-2003	NUCxXVNbT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MkHxTWM2OD1zMT6wPFkzKM7:TR?=	M4nj[3NCVkeHUh?=
J-RT3-T3-5	MlTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MkHNTWM2OD1zMT6xNlA6KM7:TR?=	NIG1bHdUSU6JRWK=
DoTc2-4510	MkG0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmDRTWM2OD1zMT6xN\|g6KM7:TR?=	NGPrRpNUSU6JRWK=
HLE	MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NFXKeGlKSzVyPUGxMlIyOTlizszN	MknaV2FPT0WU
SW626	NFP0cphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVjBemh1UUN3ME2xNU4zQDh7IN88US=>	MWjTRW5ITVJ?
COR-L105	MmjIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M3LNemlEPTB;MUGuN\|I{PyEQvF2=	M3zpV3NCVkeHUh?=
ES6	NEPSb4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NH73doNKSzVyPUGxMlU4PiEQvF2=	MYnTRW5ITVJ?
SNU-449	NIXvRpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXf0c2F3UUN3ME2xNU43ODd{IN88US=>	NFHHWpFUSU6JRWK=
GR-ST	Ml\VS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NEX1XYlKSzVyPUGxMlYyQDFizszN	M2X3[HNCVkeHUh?=
BL-41	NX\Mc5lnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4T6OWlEPTB;MUGuO\|E4OyEQvF2=	MmHZV2FPT0WU
GB-1	MnfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NG\ycI5KSzVyPUGxMlc3OTlizszN	NFXNfXpUSU6JRWK=
COLO-320-HSR	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1jSRmlEPTB;MUGuPFUyQSEQvF2=	NXTQUWtZW0GQR1XS
L-540	NYDLS2tFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MoXlTWM2OD1zMT64PVkh\|ryP	MlXDV2FPT0WU
NCI-H69	MlTVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NILkXYhKSzVyPUGyMlAyOzlizszN	NYP4dG5zW0GQR1XS
769-P	M3TT[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1frZWlEPTB;MUKuNFE6KM7:TR?=	MYHTRW5ITVJ?
A172	NETKenRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnTVTWM2OD1zMj6xNlA4KM7:TR?=	Ml\CV2FPT0WU
CAL-27	NITzeZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWrJR\|UxRTF{LkGzOlkh\|ryP	MX;TRW5ITVJ?
NCI-H1437	MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MXfJR\|UxRTF{LkG0OFch\|ryP	NYfUWXUyW0GQR1XS
REH	NHr4[HNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MojKTWM2OD1zMj6xOVc{KM7:TR?=	Mn7zV2FPT0WU
KINGS-1	MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M{jEcGlEPTB;MUKuN\|QzOSEQvF2=	NUDyeW5LW0GQR1XS
NCI-H1792	M4PWWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MlnMTWM2OD1zMj6zPFUyKM7:TR?=	MmTJV2FPT0WU
SK-MM-2	M2DR[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MUTJR\|UxRTF{LkSwPFch\|ryP	M1L6fHNCVkeHUh?=
8505C	NVTic\|NIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXvJR\|UxRTF{Lk[xNkDPxE1?	MU\TRW5ITVJ?
HAL-01	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NYnKS\|BVUUN3ME2xNk43OTd2IN88US=>	MmjHV2FPT0WU
NCI-H2141	Mkf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2npPWlEPTB;MUKuOlU5KM7:TR?=	NIHJc4FUSU6JRWK=
HCC1806	M2TxPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NX\5b5NxUUN3ME2xNk43QTV{IN88US=>	MY\TRW5ITVJ?
LU-134-A	NGj3[ZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVXs[mhOUUN3ME2xNk46OyEQvF2=	MWnTRW5ITVJ?
HT	M1XMb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MVPJR\|UxRTF{Lkm0N\|ch\|ryP	MoL5V2FPT0WU
OE33	MmDMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MkTNTWM2OD1zMj65OFU3KM7:TR?=	MWXTRW5ITVJ?
ES4	NUnlbYU2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3;D[2lEPTB;MUKuPVQ5PyEQvF2=	MmXCV2FPT0WU
SW948	NV3nclNiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NWrwT2xuUUN3ME2xN{4xOTNizszN	MW\TRW5ITVJ?
LB2241-RCC	NEjK[oZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MYLJR\|UxRTF\|LkG0Olkh\|ryP	NWXw[VE4W0GQR1XS
CCF-STTG1	M1;qXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M375T2lEPTB;MUOuOFA{QSEQvF2=	M1juRXNCVkeHUh?=
RPMI-8402	MkfyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGXTU5hKSzVyPUGzMlUxOzFizszN	MV7TRW5ITVJ?
DEL	MlzvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NHXVSItKSzVyPUGzMlU2ODNizszN	Mn[4V2FPT0WU
NB5	M2DYVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoLiTWM2OD1zMz61OVA{KM7:TR?=	MljPV2FPT0WU
NUGC-3	M3XDdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NXu2XFU3UUN3ME2xN{44PDV\|IN88US=>	NVXZTlZwW0GQR1XS
CAL-72	MkOwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUXJR\|UxRTF2LkG5NFYh\|ryP	NGPZdmZUSU6JRWK=
VMRC-RCZ	M1PRTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M4LCWmlEPTB;MUSuNlM3KM7:TR?=	MlvYV2FPT0WU
YAPC	Mn3mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MlOwTWM2OD1zND6yOFA4KM7:TR?=	NULURXRsW0GQR1XS
ES5	NWrDVIs4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYntVI9wUUN3ME2xOE4zPTl7IN88US=>	MkfxV2FPT0WU
CAL-12T	Mn;0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFrLRXRKSzVyPUG0MlQ{OzZizszN	M2fC[XNCVkeHUh?=
GAMG	NWLRbmlFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NH:1ZWZKSzVyPUG0MlU2PzdizszN	M1fUXXNCVkeHUh?=
BT-20	MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NWPWc292UUN3ME2xOE46Ozh2IN88US=>	MXfTRW5ITVJ?
KALS-1	Mny3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NVq0cXhoUUN3ME2xOU4xOTV6IN88US=>	M3HjeHNCVkeHUh?=
LS-123	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXGzfFdzUUN3ME2xOU4xOTZ3IN88US=>	MnPKV2FPT0WU
LK-2	NEfHdHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Ml\rTWM2OD1zNT6wPFYzKM7:TR?=	MXXTRW5ITVJ?
NCI-H1770	M1jQXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIjGbWFKSzVyPUG1MlI5PjhizszN	MV;TRW5ITVJ?
MIA-PaCa-2	NFfGbJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MoXnTWM2OD1zNT60NVY{KM7:TR?=	NYnqdGFFW0GQR1XS
DB	NFnzUGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWLJR\|UxRTF3Lk[5OFEh\|ryP	NETzUFVUSU6JRWK=
Becker	M1rwT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NELL[GtKSzVyPUG1Mlg6OjZizszN	NEj4UJdUSU6JRWK=
HT-144	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVfJR\|UxRTF3Lkm0PVch\|ryP	M13OfnNCVkeHUh?=
NCI-H2405	MlfGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NUHjdnAxUUN3ME2xOk4zOjF6IN88US=>	NUXTXpZ[W0GQR1XS
TK10	NX;sNYJFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NX7TOXVkUUN3ME2xOk4{PzR{IN88US=>	MV;TRW5ITVJ?
THP-1	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NWT1XlFuUUN3ME2xOk41PjZ3IN88US=>	NWL3XVRZW0GQR1XS
LB373-MEL-D	NVT4SWMxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MofrTWM2OD1zNj62NVM5KM7:TR?=	NVqzdIZ5W0GQR1XS
SJSA-1	MontS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NIXF[VNKSzVyPUG2MlkzOTlizszN	NInjc2JUSU6JRWK=
EB2	MmLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2L6[mlEPTB;MUeuO\|QzPiEQvF2=	NUnLXY9iW0GQR1XS
MN-60	NVLmT3hmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3jNT2lEPTB;MUeuO\|k{PiEQvF2=	M{\vPHNCVkeHUh?=
A253	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M3PiVWlEPTB;MUeuPFI2KM7:TR?=	NX7vUoFZW0GQR1XS
CESS	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MnjJTWM2OD1zNz65N\|I3KM7:TR?=	NHHTWI1USU6JRWK=
EW-11	M4K2T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1LXR2lEPTB;MUeuPVk2QCEQvF2=	M4PNbnNCVkeHUh?=
TE-8	M2HO[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NXvpfotrUUN3ME2xPE4xPjZ7IN88US=>	M4e5RnNCVkeHUh?=
UACC-257	M3zO[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NGnmZoxKSzVyPUG4MlIxPjJizszN	MoPBV2FPT0WU
NCI-H226	NYm2bHFMT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYLJR\|UxRTF6LkiyPVkh\|ryP	NIL3dm5USU6JRWK=
NCI-H748	MkXmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NVXHN\|d[UUN3ME2xPE45PTh3IN88US=>	NIj1WFdUSU6JRWK=
NCI-H1299	NWrUW5lbT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYTJR\|UxRTF6Lki5NVgh\|ryP	MnvyV2FPT0WU
IST-MEL1	MojIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmL5TWM2OD1zOT6xO\|U1KM7:TR?=	MXnTRW5ITVJ?
HCC1187	Moi5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXTwSopFUUN3ME2xPU4yPzl4IN88US=>	NIHiZnlUSU6JRWK=
HT-1376	M{LY[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1\6[GlEPTB;MUmuNlAzQSEQvF2=	M1fJUnNCVkeHUh?=
SK-MEL-2	NVf0cHpuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M2HaNGlEPTB;MUmuNlE2PSEQvF2=	NHv1T3dUSU6JRWK=
U031	MoPYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NVvqZXdOUUN3ME2xPU4zOjF7IN88US=>	MmPMV2FPT0WU
NCI-H524	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MkTiTWM2OD1zOT61O\|I2KM7:TR?=	MW\TRW5ITVJ?
KU812	Mlj1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXS2e3I4UUN3ME2xPU42QTR2IN88US=>	NVPxb3JOW0GQR1XS
NB10	M3znemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mn;jTWM2OD1zOT62NlY5KM7:TR?=	MmXDV2FPT0WU
NOS-1	MnvvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUTJR\|UxRTJyLkG1O\|ch\|ryP	NGDUWGRUSU6JRWK=
EW-7	NHT4N4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Mkf1TWM2OD1{MD6xOlI5KM7:TR?=	MkLrV2FPT0WU
Raji	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NF;ZOFNKSzVyPUKwMlI2PjhizszN	MlvJV2FPT0WU
LB2518-MEL	MlzoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MWrJR\|UxRTJyLkO5OVMh\|ryP	Mkn5V2FPT0WU
PANC-10-05	M3vZTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1[3OWlEPTB;MkCuOFYyOyEQvF2=	MoOyV2FPT0WU
MZ2-MEL	MkPKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NV\Xd4VWUUN3ME2yNE42QDF2IN88US=>	NVjKNHZvW0GQR1XS
MFE-280	MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NFrLV\|dKSzVyPUKxMlMyQDhizszN	NWjNRoZLW0GQR1XS
RKO	MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4nCW2lEPTB;MkGuN\|IxOiEQvF2=	NITNVVBUSU6JRWK=
KMOE-2	NYj0R49HT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYPyclV[UUN3ME2yNU4{Ojh6IN88US=>	M1HMUnNCVkeHUh?=
K5	NHjxPIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NUDFbYJoUUN3ME2yNU4{QDl\|IN88US=>	NVrlTHg4W0GQR1XS
NCI-H64	NXixN4hnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYPJR\|UxRTJzLkS3OVYh\|ryP	NHPVNItUSU6JRWK=
K-562	M1\uN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1zhT2lEPTB;MkGuOFk4OSEQvF2=	MnjpV2FPT0WU
HCE-T	NHzZOotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NF\IdVZKSzVyPUKxMlUxQTRizszN	MWXTRW5ITVJ?
COLO-792	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MX;JR\|UxRTJzLkW4Nlch\|ryP	NF65bmxUSU6JRWK=
PFSK-1	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NI\1e5NKSzVyPUKxMlY5OzdizszN	M2\Ud3NCVkeHUh?=
DOK	MlH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NEfGd4JKSzVyPUKxMlc3QDdizszN	NHfoeIZUSU6JRWK=
NCI-H1882	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1vuW2lEPTB;MkGuPFU6PiEQvF2=	MV;TRW5ITVJ?
KNS-81-FD	M{\SVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M{H2cmlEPTB;MkGuPFY{OSEQvF2=	MWjTRW5ITVJ?
OCUB-M	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVPJR\|UxRTJzLkm2PFgh\|ryP	MYDTRW5ITVJ?
NCI-H1694	NUjVS3I{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnrPTWM2OD1{MT65PFY{KM7:TR?=	Ml;CV2FPT0WU
LS-513	MoTRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NHLp[pBKSzVyPUKyMlA{PjdizszN	NI\FTJhUSU6JRWK=
NCI-H2122	NGK0WoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnnrTWM2OD1{Mj6xOlc4KM7:TR?=	M2OydHNCVkeHUh?=
IMR-5	NEjsWVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVHJR\|UxRTJ{LkK4O{DPxE1?	NUPqWmxNW0GQR1XS
SNU-C2B	NHTqZlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWHJR\|UxRTJ{Lk[3OFYh\|ryP	NXLlRYw2W0GQR1XS
A498	NXHENmdNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MofpTWM2OD1{Mj64NVc4KM7:TR?=	Ml7TV2FPT0WU
NCI-H727	NUTXeoZNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGX3RppKSzVyPUKyMlg5OzZizszN	MUPTRW5ITVJ?
SW1573	NGW0N5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnXTTWM2OD1{Mz6wOlQ3KM7:TR?=	MnjYV2FPT0WU
RO82-W-1	MoC2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnOyTWM2OD1{Mz6yOVEyKM7:TR?=	NUHRcIRlW0GQR1XS
SKG-IIIa	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlvZTWM2OD1{Mz6zOVQ3KM7:TR?=	MYjTRW5ITVJ?
MC-CAR	NWPjbnM2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MmPuTWM2OD1{Mz61NVg{KM7:TR?=	NIPs[41USU6JRWK=
NCI-H446	MkDpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVTJR\|UxRTJ\|Lk[wPVMh\|ryP	NXfYUXVQW0GQR1XS
PC-14	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4KzS2lEPTB;MkOuOlYzOyEQvF2=	MljVV2FPT0WU
TGBC1TKB	M1LrV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYnJR\|UxRTJ\|Lke0OlEh\|ryP	NIPwXo9USU6JRWK=
EFM-19	M1L0bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmjMTWM2OD1{ND6xPFQ1KM7:TR?=	M2\WdXNCVkeHUh?=
SK-N-DZ	NVfZfmk{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXLJR\|UxRTJ2LkS5O\|ch\|ryP	MV;TRW5ITVJ?
NCI-H661	Ml64S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYDJR\|UxRTJ2LkWyNVch\|ryP	NH7NdGhUSU6JRWK=
SW1990	NUTV[pVRT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYHaRVNOUUN3ME2yOE42QDh\|IN88US=>	MnvtV2FPT0WU
SW684	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NYDoPIVbUUN3ME2yOE44PjJ2IN88US=>	MVLTRW5ITVJ?
Ca-Ski	Mn7WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnW0TWM2OD1{ND65NlM4KM7:TR?=	MVfTRW5ITVJ?
TGW	NIS4TXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXTRTlRuUUN3ME2yOU4zOzN5IN88US=>	MXTTRW5ITVJ?
CaR-1	NVHPd4EzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M1vVUWlEPTB;MkWuN\|U4KM7:TR?=	NWPle2d4W0GQR1XS
D-247MG	M4n4Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mlz5TWM2OD1{NT60O\|Q{KM7:TR?=	MoDHV2FPT0WU
CCRF-CEM	M4XD[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NV\Sc4dIUUN3ME2yOU44PDV7IN88US=>	NYPpc4p4W0GQR1XS
CAPAN-1	MlTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MkDGTWM2OD1{NT63OVAyKM7:TR?=	NV:4dHZXW0GQR1XS
CP50-MEL-B	MljjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NIPRTWFKSzVyPUK1Mlk6ODFizszN	MVnTRW5ITVJ?
FADU	M1r6UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIPyXWZKSzVyPUK2MlUyPTJizszN	NEnFO3BUSU6JRWK=
Daudi	M1zKdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYHBd2lQUUN3ME2yOk42OTV6IN88US=>	MUjTRW5ITVJ?
U-87-MG	M{fJeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NWjUOFB6UUN3ME2yOk42OzB3IN88US=>	M{D3VnNCVkeHUh?=
DSH1	MkO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M{W4emlEPTB;Mk[uOVQxPiEQvF2=	MmPXV2FPT0WU
KYSE-520	NFv4NlZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MYfJR\|UxRTJ4LkW1OVMh\|ryP	NXnDZYR6W0GQR1XS
HuH-7	M3vF[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M4[1fmlEPTB;Mk[uPVA5PiEQvF2=	MnrWV2FPT0WU
U-2-OS	M2D5SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NUPSW3VXUUN3ME2yO{4xOjdzIN88US=>	NFTMUmJUSU6JRWK=
LU-99A	NUC0OYNQT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVjJR\|UxRTJ5LkG3OVQh\|ryP	NGG0bmlUSU6JRWK=
T98G	NYm2fXBHT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NF\sbmRKSzVyPUK3MlE6PzNizszN	NEHocGJUSU6JRWK=
MZ7-mel	NEfpNZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NF;FZ4JKSzVyPUK3MlU2PDhizszN	M3XNbHNCVkeHUh?=
SNU-C1	NUXRcXZ6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHjLPVhKSzVyPUK3MlY1QTFizszN	Mn7RV2FPT0WU
MDA-MB-175-VII	NHjsfHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXHJR\|UxRTJ5Lk[5O\|Uh\|ryP	NYj0dlBJW0GQR1XS
HuP-T3	NY\0Z\|Q{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVG5TWg{UUN3ME2yPE4xPDl3IN88US=>	M3\6OXNCVkeHUh?=
T-24	MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MUnJR\|UxRTJ6LkG5NlUh\|ryP	MYHTRW5ITVJ?
HDLM-2	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVzJR\|UxRTJ6LkK0OVkh\|ryP	NWW4WGJXW0GQR1XS
NCI-H1651	M4LHOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoPhTWM2OD1{OD6yOVkzKM7:TR?=	NIWzT\|RUSU6JRWK=
SK-N-AS	M1Ho[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NV3QXot6UUN3ME2yPE4{OTdzIN88US=>	NIjEc4xUSU6JRWK=
NY	NX7XNHd2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MV\JR\|UxRTJ6Lk[1O\|kh\|ryP	M{[xOnNCVkeHUh?=
D-283MED	NGGxRWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NG\1UpdKSzVyPUK4Mlg4ODhizszN	NH3nTG5USU6JRWK=
KLE	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2ftVGlEPTB;MkiuPVkxPiEQvF2=	MoLNV2FPT0WU
NCI-H28	M3PNTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NFX2eWNKSzVyPUK5MlAyOiEQvF2=	MWHTRW5ITVJ?
TE-1	NFK3WndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4nkO2lEPTB;MkmuNlE3PyEQvF2=	NUXTcXFKW0GQR1XS
SK-MEL-24	NYr4ZpEyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NFG3foNKSzVyPUK5MlU1PjZizszN	NH7GSJlUSU6JRWK=
CAL-54	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MoexTWM2OD1{OT62NFQ3KM7:TR?=	M1LST3NCVkeHUh?=
A673	NVO4VJd[T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M2HOOmlEPTB;MkmuO\|MzKM7:TR?=	M2DJdHNCVkeHUh?=
HEC-1	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MU\JR\|UxRTNyLkCwOVMh\|ryP	MnT0V2FPT0WU
LS-411N	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVPJR\|UxRTNyLkG0O\|Uh\|ryP	NYrIcHBbW0GQR1XS
SW962	MlP5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4HLdmlEPTB;M{CuNlQ4PyEQvF2=	MUnTRW5ITVJ?
OVCAR-8	NWLXclBKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnTUTWM2OD1\|MD62O\|k1KM7:TR?=	NYTNWZZ4W0GQR1XS
NCI-H630	NGPPdYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWrJR\|UxRTNyLki5OVMh\|ryP	NGH5d4VUSU6JRWK=
D-263MG	MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NUmwcmNFUUN3ME2zNU4xPDJ2IN88US=>	Mn7vV2FPT0WU
NCI-H596	M3Pz[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NEjDboFKSzVyPUOxMlA3OjFizszN	M1jafXNCVkeHUh?=
BB49-HNC	MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NX\lXnhYUUN3ME2zNU4yOTJizszN	MkPzV2FPT0WU
KYSE-70	MnTGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUXJR\|UxRTNzLkOwNFgh\|ryP	NWTIUo55W0GQR1XS
LAN-6	M4PRSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NH7sd\|JKSzVyPUOxMlQ6QTJizszN	NVfrUIJZW0GQR1XS
NCI-H2228	NGjmTFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MUTJR\|UxRTNzLkW2NlUh\|ryP	M1f6SHNCVkeHUh?=
SW620	MnLQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXXJR\|UxRTNzLk[yPFMh\|ryP	M2\SXHNCVkeHUh?=
KM-H2	NFfE[GtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4SwcGlEPTB;M{GuO\|MxPiEQvF2=	M1;6XHNCVkeHUh?=
DJM-1	NG\0PYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1OwXmlEPTB;M{KuNVM5PiEQvF2=	MlG0V2FPT0WU
SW48	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlLETWM2OD1\|Mj6zPFI2KM7:TR?=	M{i0WnNCVkeHUh?=
NCI-H1793	MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NWPrSJFCUUN3ME2zNk43OTZ\|IN88US=>	M1HZcnNCVkeHUh?=
LU-165	MlT5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYr1eopUUUN3ME2zN{4xODhizszN	NIT2d4NUSU6JRWK=
EHEB	MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWXJR\|UxRTN\|LkC0PVQh\|ryP	NETjbXRUSU6JRWK=
NCI-H441	MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NIjSZlJKSzVyPUOzMlIzOzVizszN	MWrTRW5ITVJ?
LOXIMVI	M{HCNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NU\EUnFJUUN3ME2zN{4{Pjd7IN88US=>	NWjFd2U{W0GQR1XS
MC-IXC	MnnVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXTJR\|UxRTN\|LkW2OVUh\|ryP	M4To[HNCVkeHUh?=
NCI-H522	NUjNbVU{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NUDwT2JHUUN3ME2zN{43PTRizszN	M13pTXNCVkeHUh?=
IA-LM	NFO1d5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYfJOXlEUUN3ME2zN{43PzR4IN88US=>	M4P5cnNCVkeHUh?=
NCI-H1417	NUCzUYpHT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NV3TOndMUUN3ME2zN{46PTh3IN88US=>	NXXVW\|M{W0GQR1XS
HCC2218	MnTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYjCXnA4UUN3ME2zOU4zOTh3IN88US=>	NX[4dG41W0GQR1XS
HC-1	M{jPOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnPuTWM2OD1\|NT60NFI1KM7:TR?=	NHvHTm1USU6JRWK=
HH	MkLvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoHHTWM2OD1\|NT60NVQyKM7:TR?=	M3;mU3NCVkeHUh?=
EFE-184	NFTXOZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYrpUoNkUUN3ME2zOU43QDJ7IN88US=>	MWfTRW5ITVJ?
NCI-H1355	NXPCV\|ViT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVXtUpZoUUN3ME2zOU44PzF6IN88US=>	MU\TRW5ITVJ?
BV-173	NHLkOFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnfKTWM2OD1\|NT64NlY1KM7:TR?=	MYPTRW5ITVJ?
NEC8	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Ml75TWM2OD1\|Nj60PVI1KM7:TR?=	M3;TdnNCVkeHUh?=
SW1463	NE\PTXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYq2cnV{UUN3ME2zOk43PTZ4IN88US=>	NVHWflU5W0GQR1XS
KYSE-140	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NW\aOG8xUUN3ME2zOk44Ojl6IN88US=>	MorwV2FPT0WU
no-11	MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1;MZWlEPTB;M{[uPFU{PiEQvF2=	MV7TRW5ITVJ?
HCC1937	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXPYTnVFUUN3ME2zO{4xOTV2IN88US=>	M3fwZ3NCVkeHUh?=
LNCaP-Clone-FGC	M33ZWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mo\1TWM2OD1\|Nz6xPVA{KM7:TR?=	NXPafIxwW0GQR1XS
KARPAS-422	MkXyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFjyeG9KSzVyPUO3MlQ1OzFizszN	NWPU[pBrW0GQR1XS
RCM-1	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MV3JR\|UxRTN5LkWzOVgh\|ryP	MWnTRW5ITVJ?
A375	M{DKemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVHqZW1ZUUN3ME2zO{44PjR5IN88US=>	NE\Fe2NUSU6JRWK=
TGBC24TKB	NIO2bWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2Po[mlEPTB;M{iuNFI{QSEQvF2=	MYfTRW5ITVJ?
MDA-MB-453	NVPyNWFyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MkftTWM2OD1\|OT6wNlE5KM7:TR?=	MWfTRW5ITVJ?
Capan-2	NHT1PVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXP4O415UUN3ME2zPU4xPTB7IN88US=>	MkjFV2FPT0WU
SW756	MmDaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NV[0SpV7UUN3ME2zPU42ODlzIN88US=>	M{DWTnNCVkeHUh?=
KU-19-19	M373eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NFywbIVKSzVyPUO5MlYzQDJizszN	MlrOV2FPT0WU
NCI-H2170	MmjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXXIeHo{UUN3ME2zPU46QTd5IN88US=>	NHm3OYpUSU6JRWK=
COLO-678	MnjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M37FdGlEPTB;NECuOVk2KM7:TR?=	M2\kZXNCVkeHUh?=
PF-382	M2\yWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYizOpNIUUN3ME20NE44PDh5IN88US=>	MknvV2FPT0WU
OAW-42	NEjZO3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWHJR\|UxRTR{LkK5OFIh\|ryP	NVvRWldMW0GQR1XS
LB996-RCC	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2n1d2lEPTB;NEKuPFAxQCEQvF2=	NWT0S4p5W0GQR1XS
SAS	M{iyTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Ml7qTWM2OD12Mz60Nlg5KM7:TR?=	NWLDSFJsW0GQR1XS
MRK-nu-1	NF7scGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NGfiZ2lKSzVyPUS0Mlc1OTRizszN	M1:2U3NCVkeHUh?=
EoL-1-cell	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Mk[4TWM2OD12ND65NVM3KM7:TR?=	NVW0fJo6W0GQR1XS
NCI-H2342	MmjLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1i0W2lEPTB;NEWuNVEyPyEQvF2=	NVr4SVVnW0GQR1XS
NCI-H1703	Mnf0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGC4XI9KSzVyPUS2MlA2QTJizszN	MWHTRW5ITVJ?
NCI-H187	NF;ufnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NELKWXpKSzVyPUS2MlE5PjlizszN	NX70[HQ{W0GQR1XS
CP66-MEL	NVf3TpNiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGf6bVlKSzVyPUS2MlI4QDlizszN	NXHPTpdXW0GQR1XS
HCC1569	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NF;WeItKSzVyPUS2MlU6OTdizszN	MV\TRW5ITVJ?
BL-70	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NIXBN41KSzVyPUS2Mlc4OzdizszN	NGjNWHFUSU6JRWK=
Saos-2	NH3aSFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Mn[zTWM2OD12Nz6zNVI{KM7:TR?=	NV2wPFM2W0GQR1XS
LC-1F	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MnzNTWM2OD12Nz62NVA2KM7:TR?=	MVPTRW5ITVJ?
KY821	M4\sOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MlvFTWM2OD12Nz62OFM1KM7:TR?=	Mn\mV2FPT0WU
PSN1	NUfGWms6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NWHMc285UUN3ME20PE4yPDBzIN88US=>	MYHTRW5ITVJ?
RT4	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NHHXVWNKSzVyPUS4Mlg{PzdizszN	NXXLZXpiW0GQR1XS
LS-1034	MlXCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUjJR\|UxRTR6Lki5OVQh\|ryP	NHnYXJVUSU6JRWK=
NCI-H1395	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4TKUGlEPTB;NEmuNFQ6OiEQvF2=	NHjNclZUSU6JRWK=
EKVX	MmjoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MYHJR\|UxRTR7Lk[3N\|Eh\|ryP	MVzTRW5ITVJ?
IST-MES1	MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MX\JR\|UxRTR7Lki5OFQh\|ryP	MUHTRW5ITVJ?

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	p-FAK / FAK / p-Talin / Talin ; PubMed: 26530902 Cancer Res Dose response of PF-562271 on the phosphorylation of FAK-Y397 or Talin-S425 in PC3-mm2 cells. p-Src / Src / p-paxillin / Paxillin / ICAM-1 ; PubMed: 29417941 Acta Pharmacol Sin MDA-MB-231 cells transfected with FAK-specific siRNAs or treated for 12 h with PF-562271 at the indicated concentrations were subjected to immunoblotting with indicated antibodies.	26530902 29417941
Immunofluorescence	p-FAK; PubMed: 26530902 Cancer Res Immunostaining of PC3-mm2 cells showed that phosphorylated FAK is localized at focal adhesions (inset).	26530902
Growth inhibition assay	Cell viability; PubMed: 28953264 Nutrients MTT assay showed inhibition of cell proliferation and viability in HCT116 (B) and SW480 (D) cell lines treated with resveratrol and/or different concentrations of FAK-Inhibitor (PF-562271: 0.01, 0.1, 1, and 10 µM) cultured in monolayer for 12 h. Data shown are representative of three independent sets of experiments. Values were compared with the control and statistically significant values with p < 0.05 are designated by an asterisk () and p < 0.01 are designated by two asterisks (*).	28953264

体内研究

在携带U87MG的小鼠中PF-562271 (< 33 mg/kg 口服)抑制肿瘤中FAK磷酸化并具有时间和剂量依赖特性。PF-562271 (50 mg/kg, 口服，一天两次)对BxPc3异种移植小鼠中肿瘤生长抑制率为86% ，对PC3-M异种移植小鼠中肿瘤生长抑制率为45%。PF-562271 (25mg/kg, 一天两次)处理的携带H125肺部异种移植肿瘤凋亡率提高2倍^[1]。 PF-562271 (33 mg/kg,口服)24小时后抑制小鼠中肿瘤细胞的广泛运动。PF-562271 (33 mg/kg, 口服)导致小鼠中E-cadherin动力学的改变，这与减弱的E-cadherin依赖的整体细胞运动有关 ^[3]。在皮下局部异种移植PC3M-luc-C6的小鼠模型中 PF-562271 (25 mg/kg, 口服，一天两次)导致肿瘤生长率62%的抑制^[4]。在胫骨植入MDA-MB-231细胞的大鼠中PF-562271 (5mg/kg, 口服)导致骨钙素和松质骨参数显著而相似的增加同时导致肿瘤生长速度和骨愈合信号的下降^[5]。

动物实验：^[1]	- 合并 Animal Models: 携带BxPc3或 PC3-M异种移植的无胸腺雌性小鼠 Dosages: 50 mg/kg Administration: 填喂给药 (Only for Reference)

参考文献

- 合并

溶解度 (25°C)

体外	DMSO	100 mg/mL warmed (197.04 mM)
	Water	Insoluble
	Ethanol	Insoluble
体内	从左到右依次将纯溶剂加入产品，现配现用(数据来自Selleck实验检测而非文献)： 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O	5 mg/ml

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据 Download PF-562271 SDF

分子量	507.49
化学式	C₂₁H₂₀F₃N₇O₃S
CAS号	717907-75-0
储存条件	3年-20°C 粉状 2年-80°C 溶于溶剂
别名	N/A

动物体内配方计算器 (澄清溶液)

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）

% DMSO+ % + % Tween 80+ % ddH₂O

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

质量

浓度

体积

分子量
=

×

×

*在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入输出 )

C1

V1

C2

V2
×

=

×

在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量计算器

通过输入化合物的化学式来计算其分子量：

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量	浓度	体积	分子量
=	×	×
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

研究领域

产品类型

定制您的化合物库

PF-562271

客户使用Selleck生产的PF-562271发表文献80篇：

产品安全说明书

FAK抑制剂选择性比较

生物活性

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

参考文献

溶解度 (25°C)

化学数据 Download PF-562271 SDF

动物体内配方计算器 (澄清溶液)

计算器

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

稀释计算器

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

连续稀释计算器方程

连续稀释

计算结果

分子量计算器

总分子量：g/mol

摩尔浓度计算器

技术支持

FAK Signaling Pathway Map

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