PF-562271

For research use only. Not for use in humans.

目录号：S2890

CAS No. 717907-75-0

PF-562271是一种有效的，ATP竞争性的，可逆的FAK抑制剂，无细胞试验中IC50为1.5 nM，作用于FAK比作用于Pyk2选择性高10倍左右，比作用于其他蛋白激酶（除了一些CDKs）选择性高100倍以上。

规格

价格

库存

购买数量

10mM (1mL in DMSO)	RMB 2862.96	现货
5mg	RMB 1392.84	现货
10mg	RMB 2194.82	现货
50mg	RMB 5469.68	现货
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客户使用Selleck生产的PF-562271发表文献87篇：

Cancer Cell, 2019, 36(2):179-193

PubMed: 31378681 ( click the link to review the publication )

Cell, 2019, 36(2):179-193

PubMed: 28162770 ( click the link to review the publication )

J Clin Invest, 2020, 1;130(5):2422-2434

PubMed: 32250340 ( click the link to review the publication )

Nat Commun, 2020, 11(1):3282

PubMed: 32612176 ( click the link to review the publication )

EMBO Mol Med, 2020, e12010

PubMed: 33025708 ( click the link to review the publication )

ACS Appl Mater Interfaces, 2020, 15

PubMed: 32485098 ( click the link to review the publication )

Cell Rep, 2020, 30(6):1780-1797

PubMed: 32049010 ( click the link to review the publication )

Elife, 2020, 4;9:e50571

PubMed: 32017701 ( click the link to review the publication )

Cancers (Basel), 2020, 12(12)E3708

PubMed: 33321813 ( click the link to review the publication )

Cell Death Dis, 2020, 14;11(4):230

PubMed: 32286266 ( click the link to review the publication )

Aging (Albany NY), 2020, 7;12(9):8221-8240

PubMed: 32379705 ( click the link to review the publication )

Sci Rep, 2020, 10(1):419

PubMed: 31942012 ( click the link to review the publication )

J Biol Chem, 2020, jbc.RA120.012957

PubMed: 32934005 ( click the link to review the publication )

J Biol Chem, 2020, 12 pii: jbc

PubMed: 32280065 ( click the link to review the publication )

Cell Cycle, 2020, 14:1-13

PubMed: 32286145 ( click the link to review the publication )

Cancer Med, 2020, 10.1002/cam4.3621

PubMed: 33280262 ( click the link to review the publication )

Cells, 2020, 9(1)

PubMed: 31905606 ( click the link to review the publication )

Mol Cancer Ther, 2020, 19(2):637-649

PubMed: 31784455 ( click the link to review the publication )

Biochem Biophys Res Commun, 2020, S0006-291X(20)32148-3

PubMed: 33272569 ( click the link to review the publication )

Clin Cancer Res, 2019, 25(14):4552-4566

PubMed: 30979745 ( click the link to review the publication )

Sci Signal, 2019, 12(565)

PubMed: 30670633 ( click the link to review the publication )

Cell Death Dis, 2019, 10(10):738

PubMed: 31570694 ( click the link to review the publication )

J Biol Chem, 2019, 294(18):7221-7230

PubMed: 30846565 ( click the link to review the publication )

J Tissue Eng Regen Med, 2019, 13(4):625-636

PubMed: 30770650 ( click the link to review the publication )
J Cancer Res Clin Oncol, 2019, 145(6):1461-1469

PubMed: 31006845 ( click the link to review the publication )

Molecules, 2019, 24(10)

PubMed: 31109130 ( click the link to review the publication )

J Pharm Biomed Anal, 2019, 168:163-173

PubMed: 30807921 ( click the link to review the publication )

Mol Med Rep, 2019, 19(6):4753-4760

PubMed: 31059085 ( click the link to review the publication )

Zygote, 2019, 27(3):173-179

PubMed: 31171046 ( click the link to review the publication )

Cell Rep, 2018, 22(10):2784-2796

PubMed: 29514104 ( click the link to review the publication )

Oncogene, 2018, 37(22):2953-2966

PubMed: 29515233 ( click the link to review the publication )

Oncogene, 2018, 37(23):3166-3182

PubMed: 29545604 ( click the link to review the publication )

Cell Death Dis, 2018, 9(9):848

PubMed: 30154481 ( click the link to review the publication )

Cancer Sci, 2018, 109(12):3783-3793

PubMed: 30281878 ( click the link to review the publication )

J Am Heart Assoc, 2018, 7(18):e008604

PubMed: 30371220 ( click the link to review the publication )

J Cell Sci, 2018, 131(10)

PubMed: 29678906 ( click the link to review the publication )

Stem Cells Int, 2018, 2018:2190657

PubMed: 30275837 ( click the link to review the publication )

Int J Oncol, 2018, 53(4):1544-1556

PubMed: 30066854 ( click the link to review the publication )

Acta Pharmacol Sin, 2018, 10.1038/aps

PubMed: 29417941 ( click the link to review the publication )

Cell Cycle, 2018, 17(23):2577-2592

PubMed: 30488756 ( click the link to review the publication )

Oncol Rep, 2018, 40(4):2325-2333

PubMed: 30106432 ( click the link to review the publication )

Cancer Epidemiol Biomarkers Prev, 2018, 27(7):805-813

PubMed: 29654156 ( click the link to review the publication )

Sci Transl Med, 2017, 9(420)

PubMed: 29237758 ( click the link to review the publication )

Nat Commun, 2017, 8:14122

PubMed: 28098159 ( click the link to review the publication )

Mol Syst Biol, 2017, 13(1):905

PubMed: 28069687 ( click the link to review the publication )

Cancer Sci, 2017, 108(7):1347-1356

PubMed: 28406574 ( click the link to review the publication )

FEBS J, 2017, 284(17):2856-2869

PubMed: 28665039 ( click the link to review the publication )

Sci Rep, 2017, 7(1):4032

PubMed: 28642549 ( click the link to review the publication )
Mol Carcinog, 2017, 56(12):2558-2565

PubMed: 28667800 ( click the link to review the publication )

Cancer Manag Res, 2017, 9:879-889

PubMed: 29276408 ( click the link to review the publication )

Cell Signal, 2017, 38:1-9

PubMed: 28647573 ( click the link to review the publication )

Oncol Rep, 2017, 38(1):63-70

PubMed: 28560386 ( click the link to review the publication )

Onco Targets Ther, 2017, 10:5817-5826

PubMed: 29263678 ( click the link to review the publication )

Evid Based Complement Alternat Med, 2017, 2017:4535326

PubMed: 29234400 ( click the link to review the publication )

Mol Med Rep, 2017, 16(6):8937-8943

PubMed: 28990104 ( click the link to review the publication )

Oncotarget, 2017, 8(37):61742-61760

PubMed: 28977901 ( click the link to review the publication )

Oncotarget, 2017, 8(43):75102-75113

PubMed: 29088849 ( click the link to review the publication )

Biophys J, 2017, 113(7):1585-1598

PubMed: 28844472 ( click the link to review the publication )

Oncotarget, 2017, 8(29):47931-47942

PubMed: 28624785 ( click the link to review the publication )

Nat Cell Biol, 2016, 18(2):168-80

PubMed: 26689676 ( click the link to review the publication )

Nat Commun, 2016, 7:10354

PubMed: 26838601 ( click the link to review the publication )

Clin Cancer Res, 2016, 22(23):5851-5863

PubMed: 27220963 ( click the link to review the publication )

Cancer Res, 2016,

PubMed: 27216177 ( click the link to review the publication )

Cancer Lett, 2016, 376(1):188-96

PubMed: 26996299 ( click the link to review the publication )

Breast Cancer Res, 2016, 18(1):81

PubMed: 27495308 ( click the link to review the publication )

Oral Oncology, 2016, 10.1016/j.oraloncology.2016.05.010

PubMed: ( click the link to review the publication )

Sci Rep, 2016, 6:36214

PubMed: 27796369 ( click the link to review the publication )

J Biol Chem, 2016, 291(15):8140-9

PubMed: 26865633 ( click the link to review the publication )

Mol Pharmacol, 2016, 89(5):521-40

PubMed: 26895766 ( click the link to review the publication )

J Proteome Res, 2016, 15(12):4369-4386

PubMed: 27762562 ( click the link to review the publication )

Int J Biochem Cell Biol, 2016, 71:62-71

PubMed: 26693891 ( click the link to review the publication )

Oncotarget, 2016, 7(30):48093-48106

PubMed: 27344177 ( click the link to review the publication )
Sci Rep, 2016, 6:19261

PubMed: 26763933 ( click the link to review the publication )

Oncotarget, 2016, 7(29):45186-45198

PubMed: 27286256 ( click the link to review the publication )

Nat Cell Biol, 2015, 17(11):1412-21

PubMed: 26436690 ( click the link to review the publication )

Elife, 2015, 4

PubMed: 26274564 ( click the link to review the publication )

Oncogene, 2015, 34(40):5114-27

PubMed: 25639872 ( click the link to review the publication )

Cell Physiol Biochem, 2015, 37(2):515-26

PubMed: 26330161 ( click the link to review the publication )

J Biol Chem, 2015, 290(14):8677-92

PubMed: 25713079 ( click the link to review the publication )

Environ Toxicol Pharmacol, 2015, 39(1):114-24

PubMed: 25481308 ( click the link to review the publication )

Proc Natl Acad Sci U S A, 2015, 112(20):E2595-601

PubMed: 25941386 ( click the link to review the publication )

Oncotarget, 2015, 6(27):23776-92

PubMed: 26068982 ( click the link to review the publication )

Oncotarget, 2015, 6(28):25755-69

PubMed: 26342198 ( click the link to review the publication )

Oncotarget, 2015, 6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

PLoS One, 2014, 9(2):e88587

PubMed: 24523919 ( click the link to review the publication )

Cancer Sci, 2013, 104(12):1618-25

PubMed: 24112719 ( click the link to review the publication )

Int J Clin Exp Pathol, 2013, 6(10):2082-91

PubMed: 24133586 ( click the link to review the publication )

产品安全说明书

FAK抑制剂选择性比较

生物活性

产品描述

靶点

FAK ^[1] (Cell-free assay)	PYK2 ^[1] (Cell-free assay)	CDK2/CyclinE ^[1] (Cell-free assay)	CDK3/CyclinE ^[1] (Cell-free assay)	CDK1/CyclinB ^[1] (Cell-free assay)	点击更多
1.5 nM	13 nM	30 nM	47 nM	58 nM	点击更多

体外研究

PF-562271会结合到ATP与FAK结合的部位,在激酶铰链区形成抑制剂与主链原子之间的两种氢键。PF-562271在测量FAK磷酸化可诱导的基于细胞的分析中效果很好，IC50为5 nM。PF-562271 (3.3 μM)导致PC3-M细胞周期停滞在G1期^[1]。在鸡胚绒毛尿囊膜实验中PF-562271 (1nM)阻断bFGF刺激的血管生成。 PF-262271 强有效的阻断血管生长但对血管渗漏没有明显影响^[2]。PF-562271 (250 nM)可以完全抑制整体A431 细胞侵入胶原蛋白中^[3]。

Cell Data

Cell Lines	Assay Type	Activity Description	PMID
MV-4-11	NVf0cI5KT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4jjXWlEPTB;MD6yO\|Y3KM7:TR?=	MYDTRW5ITVJ?
SW982	NHPoV5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MlPITWM2OD1yLkOyPFIh\|ryP	MVHTRW5ITVJ?
KM12	NX62eXZPT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NIrOWXFKSzVyPUCuN\|g2PTdizszN	MXXTRW5ITVJ?
COLO-205	NGXnfWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MmDvTWM2OD1yLkS4OlU5KM7:TR?=	NUfQ[GhFW0GQR1XS
COLO-829	MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NGGzXHJKSzVyPUCuO\|UyPzZizszN	MXHTRW5ITVJ?
MG-63	M3PEcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmHGTWM2OD1yLkiwOlM4KM7:TR?=	NHz2T2NUSU6JRWK=
IGROV-1	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MUjJR\|UxRTBwOEGwN\|gh\|ryP	NVPsbpc{W0GQR1XS
NCI-H650	M4fxfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYPJR\|UxRTBwOEOxOVQh\|ryP	MVjTRW5ITVJ?
RT-112	M4W5O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M{\SeGlEPTB;MD65PFQ3KM7:TR?=	NEjnTHBUSU6JRWK=
BCPAP	MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MYTJR\|UxRTFwMEGyPFgh\|ryP	MXXTRW5ITVJ?
ALL-PO	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NI\TbldKSzVyPUGuNFE2QDRizszN	NWW5R4FvW0GQR1XS
KYSE-270	M2fSSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MVnJR\|UxRTFwMES3NVQh\|ryP	MVjTRW5ITVJ?
8305C	M3\EN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NFLp[HpKSzVyPUGuNFk6ODRizszN	NH\LWplUSU6JRWK=
NCI-H810	NX\EPVNjT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M{HDXmlEPTB;MT6xNFc4PiEQvF2=	M{e0[XNCVkeHUh?=
CAL-33	MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXHMSVJiUUN3ME2xMlEzQTN6IN88US=>	M{m0R3NCVkeHUh?=
AN3-CA	NY\0bZM3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUTJR\|UxRTFwMkG4Olch\|ryP	NH\McmJUSU6JRWK=
NKM-1	NGPxeHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2K0UGlEPTB;MT6yO\|UxPiEQvF2=	M4eyc3NCVkeHUh?=
BPH-1	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NIjsNY5KSzVyPUGuNlg4PjZizszN	MVnTRW5ITVJ?
MES-SA	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NI\4dHBKSzVyPUGuN\|A3QDJizszN	MYLTRW5ITVJ?
CAL-62	NXztSZVTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXjJR\|UxRTFwM{G5NFkh\|ryP	NHjqZ4RUSU6JRWK=
Detroit562	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MUPJR\|UxRTFwM{WyNlIh\|ryP	M3S4NHNCVkeHUh?=
KYSE-150	Mn3tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Ml7lTWM2OD1zLkO1NlM3KM7:TR?=	NUfSeJV1W0GQR1XS
SK-UT-1	MmTYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnrzTWM2OD1zLkS0OlQ4KM7:TR?=	MVzTRW5ITVJ?
HUTU-80	NUTUcYhxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVnOUJQ3UUN3ME2xMlQ1QDh4IN88US=>	NYHrdGU6W0GQR1XS
SIG-M5	Mon4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2rmc2lEPTB;MT60PFM5PyEQvF2=	MVXTRW5ITVJ?
AGS	M2n2emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NFnMRpdKSzVyPUGuOVIyOjRizszN	NH7vSWZUSU6JRWK=
ST486	MmmzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MV3JR\|UxRTFwNUOyO\|gh\|ryP	MkjWV2FPT0WU
HSC-2	M3r4NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NX7XbVJqUUN3ME2xMlU{QTVizszN	MWLTRW5ITVJ?
LCLC-103H	NEPm[WxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWXJR\|UxRTFwNUW4NVgh\|ryP	M1j5XXNCVkeHUh?=
BC-1	NX7IWoUxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MkPITWM2OD1zLk[xOlY1KM7:TR?=	MmL4V2FPT0WU
CGTH-W-1	NI\jbVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYLzPI44UUN3ME2xMlYyPjd7IN88US=>	M3rPUXNCVkeHUh?=
MZ1-PC	NVe2RZk3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4LoSmlEPTB;MT62NlMyOiEQvF2=	NHLP[YNUSU6JRWK=
SW1710	MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NE\OTG9KSzVyPUGuOlI3OjhizszN	M3XrdHNCVkeHUh?=
EW-13	NY[wXJc1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NV72eYM2UUN3ME2xMlY{PDZ4IN88US=>	NGD4WZJUSU6JRWK=
TE-11	NVHFSok1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4XoRWlEPTB;MT62N\|UzOiEQvF2=	NVzybJF1W0GQR1XS
BHY	MkPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVLJR\|UxRTFwNkW2OlMh\|ryP	NFW3WGxUSU6JRWK=
ML-2	M33WdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmTrTWM2OD1zLk[2PFAzKM7:TR?=	NX\iSGl5W0GQR1XS
MEL-JUSO	M{HPRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MX;JR\|UxRTFwN{K4PVEh\|ryP	MofwV2FPT0WU
U251	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MW\JR\|UxRTFwN{SwN\|Eh\|ryP	Mk\TV2FPT0WU
MHH-ES-1	NEL6T29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MofZTWM2OD1zLke5OVY5KM7:TR?=	M2ezU3NCVkeHUh?=
CAL-85-1	MkG3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MY\JR\|UxRTFwOEC0PUDPxE1?	MUXTRW5ITVJ?
D-336MG	NU\0b5RNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVnJR\|UxRTFwOEW2NVQh\|ryP	M1fmRnNCVkeHUh?=
VA-ES-BJ	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4DEUWlEPTB;MT65NFMyPSEQvF2=	NE\hZ4hUSU6JRWK=
MDA-MB-468	MmPMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MkXHTWM2OD1zLkmxNlczKM7:TR?=	NXfic5hQW0GQR1XS
MEL-HO	NH;iRnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MmW4TWM2OD1zLkm3PVk{KM7:TR?=	MWrTRW5ITVJ?
SW954	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NU\UNFhGUUN3ME2yMlAxOTVzIN88US=>	MV7TRW5ITVJ?
LB831-BLC	MnGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGG4W\|NKSzVyPUKuNFA6QDhizszN	NXuxZmJHW0GQR1XS
EW-16	NELtU\|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVP6fnM1UUN3ME2yMlA{QTh\|IN88US=>	MofJV2FPT0WU
NCI-H460	Mmr6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUDJR\|UxRTJwMES4N\|kh\|ryP	MXPTRW5ITVJ?
CHP-212	NUexR41wT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3q1OGlEPTB;Mj6wPVU{QSEQvF2=	MoLmV2FPT0WU
MHH-NB-11	Ml;SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXL4Tox2UUN3ME2yMlEzQDF6IN88US=>	MXHTRW5ITVJ?
DU-4475	NIX0RZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWnkUoxlUUN3ME2yMlE1PzV7IN88US=>	NHeze\|NUSU6JRWK=
ABC-1	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MV7JR\|UxRTJwMkWxPVYh\|ryP	MonwV2FPT0WU
LOUCY	NGrnRllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MlXWTWM2OD1{LkK2NVI5KM7:TR?=	MWjTRW5ITVJ?
LC-2-ad	MmjXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MU\JR\|UxRTJwMk[5OlYh\|ryP	M3e4[HNCVkeHUh?=
ETK-1	Mn\FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M124T2lEPTB;Mj6yPFQ3KM7:TR?=	MWTTRW5ITVJ?
KYSE-180	NIXiNZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NUf5OldPUUN3ME2yMlI5QDd2IN88US=>	MXHTRW5ITVJ?
HOP-92	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MX\JR\|UxRTJwM{C2O\|Mh\|ryP	NIfXNJdUSU6JRWK=
RCC10RGB	MmG2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFTX[ZNKSzVyPUKuN\|I2ODdizszN	NFHnTm9USU6JRWK=
KASUMI-1	MlrrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MWjJR\|UxRTJwM{K4PEDPxE1?	MUjTRW5ITVJ?
ACN	M17FRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoX0TWM2OD1{LkO0O\|Q2KM7:TR?=	NWTjO3NiW0GQR1XS
BxPC-3	NV3VNJhuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3u4WmlEPTB;Mj6zOVQ{PiEQvF2=	MlfVV2FPT0WU
MONO-MAC-6	M1fMRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NWnFPI1wUUN3ME2yMlQyOjR6IN88US=>	NVTnUJNMW0GQR1XS
CAL-39	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWPJR\|UxRTJwNEG2Nlgh\|ryP	NIfaV49USU6JRWK=
CMK	MnvYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NHvicoRKSzVyPUKuOFE4QTVizszN	MWTTRW5ITVJ?
MFE-296	MnvhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnHETWM2OD1{LkS3O\|kzKM7:TR?=	MmXYV2FPT0WU
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KYSE-510	NEi0RopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MUXJR\|UxRTVwN{m1PFEh\|ryP	MoLTV2FPT0WU
SK-MES-1	MnPLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFLzbXFKSzVyPUWuPFU5QTFizszN	Ml;nV2FPT0WU
OVCAR-3	NHzUTYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NHjRfZRKSzVyPUWuPFgzODZizszN	MonpV2FPT0WU
LB1047-RCC	NVLh[IJIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVWweGVLUUN3ME21MlkxOTR6IN88US=>	M4jmbHNCVkeHUh?=
HEL	MnrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NX24ZlVGUUN3ME22MlAzOTh6IN88US=>	NGLE[\|ZUSU6JRWK=
KARPAS-45	MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Ml\TTWM2OD14LkCzO\|g4KM7:TR?=	MWLTRW5ITVJ?
NCI-H1304	Mmr2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1y0UGlEPTB;Nj6xNlQ6PyEQvF2=	MknnV2FPT0WU
PC-3	NVnmeG1NT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUHJR\|UxRTZwMUOwO\|Ih\|ryP	MoHNV2FPT0WU
Calu-3	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NVn5OpZkUUN3ME22MlE1Pjh7IN88US=>	MVPTRW5ITVJ?
NCI-H1648	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NFTueIRKSzVyPU[uNVUyPiEQvF2=	MX7TRW5ITVJ?
HSC-3	Ml\IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NITOOWdKSzVyPU[uNVc{QTZizszN	NVfYXIlbW0GQR1XS
COLO-824	NYjSeIxYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVzqT2VWUUN3ME22MlI4QDZ6IN88US=>	MmHhV2FPT0WU
COLO-680N	NGTNO3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NX7VZnAzUUN3ME22MlM4PjN6IN88US=>	NFP3e3BUSU6JRWK=
SK-NEP-1	M{G0UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MlPpTWM2OD14LkSwN\|Yh\|ryP	NUDUWod1W0GQR1XS
SCC-25	M2DrU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoD2TWM2OD14LkSyOFk{KM7:TR?=	NXPZd25IW0GQR1XS
SF295	M1y5cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NGX5fJhKSzVyPU[uOFQ6QCEQvF2=	NVLMOJcxW0GQR1XS
no-10	NYn3N5BIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NEmwe5RKSzVyPU[uOFc5PCEQvF2=	NUnO[ldqW0GQR1XS
NCI-H838	NYW3R3ByT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3;NNGlEPTB;Nj61NVcxOyEQvF2=	NXe3dlVxW0GQR1XS
M059J	NXfLUm46T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnLCTWM2OD14LkW1OlI2KM7:TR?=	Mn7XV2FPT0WU
Calu-6	MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2H0UGlEPTB;Nj62OVQ{PSEQvF2=	MX3TRW5ITVJ?
TE-12	NVPVNItzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MV7JR\|UxRTZwN{KzO\|ch\|ryP	M1mxWnNCVkeHUh?=
639-V	MnLmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUHJR\|UxRTZwN{WxNlch\|ryP	MXvTRW5ITVJ?
ESS-1	M4\LSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoHiTWM2OD14Lke2NFczKM7:TR?=	MnLnV2FPT0WU
C-4-II	Mk\BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NFm4N4ZKSzVyPU[uPFMyOTdizszN	MWXTRW5ITVJ?
23132-87	NGDCbnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXXJR\|UxRTZwOUC5NFEh\|ryP	MULTRW5ITVJ?
MEG-01	NYfE[4pFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M2\UWWlEPTB;Nj65N\|U1PiEQvF2=	NYD5SZlqW0GQR1XS
GI-1	NVyz[2EyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVTJR\|UxRTZwOUSzOFgh\|ryP	M1fBZnNCVkeHUh?=
NCI-H2347	MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlfaTWM2OD14Lkm0O\|E2KM7:TR?=	M{m4XXNCVkeHUh?=
MS-1	M3HmO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MVjJR\|UxRTZwOUWxPVIh\|ryP	M2\YZXNCVkeHUh?=
SK-MEL-30	MmC4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2Gye2lEPTB;Nj65OlMyPSEQvF2=	MnrrV2FPT0WU
YKG-1	NXjoSpB2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NW\ON2MyUUN3ME23MlAzPjd6IN88US=>	M1TzPXNCVkeHUh?=
HT-3	M2Premdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mn;zTWM2OD15LkCzOFkh\|ryP	M3jtT3NCVkeHUh?=
NCI-H2126	NWLwUmdLT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnnWTWM2OD15LkC5O\|kyKM7:TR?=	NHrZVphUSU6JRWK=
GI-ME-N	MmC4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4rkUWlEPTB;Nz6xOlkxPiEQvF2=	M4Dre3NCVkeHUh?=
LB771-HNC	NVzxfWZoT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MonpTWM2OD15LkG4NFM5KM7:TR?=	MlrwV2FPT0WU
LCLC-97TM1	NGfhc29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NEjnRpZKSzVyPUeuNlEzPzNizszN	NELxOJVUSU6JRWK=
HO-1-N-1	M3HYT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVW2cWJGUUN3ME23MlI1ODJ2IN88US=>	NUfkTYRKW0GQR1XS
HCC1143	M2LJTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1XhNGlEPTB;Nz6zO\|g6QCEQvF2=	MVjTRW5ITVJ?
HuO9	MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4XFbmlEPTB;Nz60PFc6PCEQvF2=	MWLTRW5ITVJ?
IST-SL2	NX;uT217T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVHJR\|UxRTdwNUKyO\|Ih\|ryP	NInrRYdUSU6JRWK=
MLMA	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWrJR\|UxRTdwNUS2PFkh\|ryP	NELXT3JUSU6JRWK=
22RV1	NWnPOYZkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MoP3TWM2OD15Lk[3PVc2KM7:TR?=	MlL3V2FPT0WU
ONS-76	M1;SV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYXJR\|UxRTdwNkm0NVYh\|ryP	M3rhRXNCVkeHUh?=
ECC12	MoPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYHINm1wUUN3ME23MlczQTBzIN88US=>	M1rhdHNCVkeHUh?=
HT-1080	MlXzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1vNU2lEPTB;Nz63PFU2PSEQvF2=	M2e5VHNCVkeHUh?=
SF268	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1XX[mlEPTB;Nz64N\|U3KM7:TR?=	MmrwV2FPT0WU
COLO-800	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NGPwdnNKSzVyPUeuPVA3QDVizszN	NYKy[ZVmW0GQR1XS
BB30-HNC	M3HPN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NV7UUHdmUUN3ME23Mlk1PTV\|IN88US=>	NVzmTpRzW0GQR1XS
CAKI-1	NEWxcVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVnERWNzUUN3ME24MlA3PTJzIN88US=>	NH;SVpVUSU6JRWK=
GCIY	Ml\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXjJR\|UxRThwMkO3NVMh\|ryP	NV\YOoN{W0GQR1XS
MKN28	MkL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1q5cGlEPTB;OD6yOFU6QCEQvF2=	MXPTRW5ITVJ?
IPC-298	MlyxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M37DV2lEPTB;OD6yO\|cxQSEQvF2=	NFKxUIhUSU6JRWK=
NCI-H1650	NXfiOW9yT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnTHTWM2OD16LkK5NVg2KM7:TR?=	NXzPflBrW0GQR1XS
KP-N-YS	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NYHyWGtZUUN3ME24MlI6OzB6IN88US=>	NVvzRnAxW0GQR1XS
J82	NEK3[ZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NH2ycIhKSzVyPUiuN\|QyOjRizszN	M2DNb3NCVkeHUh?=
SK-HEP-1	NV\LdXBbT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NF;BXYZKSzVyPUiuN\|U4OjNizszN	NIrQdHRUSU6JRWK=
PANC-03-27	MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NGfIZoNKSzVyPUiuN\|Y6OiEQvF2=	NW\YSFdoW0GQR1XS
KP-4	NHy1bFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4\XPGlEPTB;OD60NVg2OyEQvF2=	MmrGV2FPT0WU
RERF-LC-MS	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVTJR\|UxRThwNEi1PVUh\|ryP	NVPnTmFqW0GQR1XS
C-33-A	NWTLfIl{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M1;ub2lEPTB;OD62NVUzQSEQvF2=	MX;TRW5ITVJ?
PA-1	NXzpeohJT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MVTJR\|UxRThwNk[2PVQh\|ryP	NIjrfJNUSU6JRWK=
TE-5	M17FWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NGGzV\|hKSzVyPUiuO\|AzQTZizszN	NFHDdYtUSU6JRWK=
MHH-PREB-1	MkP5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NXTYXYM6UUN3ME24Mlc{OTB5IN88US=>	MlfmV2FPT0WU
C3A	M3uwNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MXvJR\|UxRThwN{[1OlEh\|ryP	MXvTRW5ITVJ?
SK-OV-3	MknKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoDJTWM2OD16Lke5O\|czKM7:TR?=	NHvWdlVUSU6JRWK=
AM-38	Mo\2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYnMS2xiUUN3ME24MlgxPDN7IN88US=>	NVvrTnBPW0GQR1XS
LoVo	M{Tabmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVXENXl4UUN3ME24Mlk2PTZ4IN88US=>	MkHHV2FPT0WU
MKN45	MkjjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYS3cFRPUUN3ME24Mlk3ODZ\|IN88US=>	MWHTRW5ITVJ?
NH-12	MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MmXUTWM2OD17LkCyOVQzKM7:TR?=	NHG3SpJUSU6JRWK=
CAMA-1	Mkj4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoryTWM2OD17LkC2NFEzKM7:TR?=	MYrTRW5ITVJ?
HT-29	NGDCfZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Mn\yTWM2OD17LkGyN\|c{KM7:TR?=	MnPtV2FPT0WU
DMS-273	NIqxflJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3PJd2lEPTB;OT6xNlUh\|ryP	NFv3fZRUSU6JRWK=
NCI-H719	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MX3JR\|UxRTlwMUizPVEh\|ryP	M4T3cXNCVkeHUh?=
SF539	NHL6WYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWDoS\|d{UUN3ME25MlIyODl6IN88US=>	M1fBe3NCVkeHUh?=
Daoy	MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MUXJR\|UxRTlwMkSxOFMh\|ryP	MXnTRW5ITVJ?
HCC70	NWPybWpCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M1HHSGlEPTB;OT6yO\|MxQSEQvF2=	M1j3cnNCVkeHUh?=
MFH-ino	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2jjcWlEPTB;OT6yPVAxPyEQvF2=	MnPlV2FPT0WU
UACC-62	MlrES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NE\Td4tKSzVyPUmuN\|czQTdizszN	M2\1XXNCVkeHUh?=
C2BBe1	NXjINGpHT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHrEfINKSzVyPUmuN\|k3PTJizszN	NHvn[pRUSU6JRWK=
KNS-42	NHzVbYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MUXJR\|UxRTlwNEO0NFch\|ryP	NVP4fWh6W0GQR1XS
SK-LMS-1	M4PuUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYnQcHhJUUN3ME25Mlc2PTN3IN88US=>	M4TMWnNCVkeHUh?=
SK-CO-1	NV\lbVBxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	Ml;KTWM2OD17Lke2NlM2KM7:TR?=	M{\1T3NCVkeHUh?=
SN12C	MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWfJR\|UxRTlwN{[4NFYh\|ryP	MkK4V2FPT0WU
HTC-C3	NVvyXplyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MWjJR\|UxRTlwN{e5PFQh\|ryP	MUnTRW5ITVJ?
OVCAR-4	M{TpW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYKyPVFkUUN3ME25Mlg1QDJ6IN88US=>	MmjHV2FPT0WU
CHP-126	NWmzZoI2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NVzNW3Y5UUN3ME25Mlk{OjlizszN	Mk\hV2FPT0WU
NCI-H716	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NWnRTIFGUUN3ME25Mlk{OzJ{IN88US=>	MWfTRW5ITVJ?
U-698-M	M1GyPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVfPcFczUUN3ME25Mlk6PyEQvF2=	MkG1V2FPT0WU
EFO-21	NITDblZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MlH3TWM2OD1zMD6wNFk{KM7:TR?=	NVr5NpNQW0GQR1XS
RXF393	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MofrTWM2OD1zMD6xN\|kzKM7:TR?=	NEPE[3pUSU6JRWK=
ChaGo-K-1	NWLQOINCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MoTXTWM2OD1zMD6xO\|c3KM7:TR?=	NWLaUopCW0GQR1XS
SJRH30	Mn3MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M2fTV2lEPTB;MUCuNVg1PCEQvF2=	MlrFV2FPT0WU
LU-65	NELMVYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4fxTmlEPTB;MUCuNlk1OyEQvF2=	M1fBbHNCVkeHUh?=
OS-RC-2	MlHvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NWC2VmY{UUN3ME2xNE4{OjJ5IN88US=>	M3PMe3NCVkeHUh?=
YT	M4W0fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M2rucmlEPTB;MUCuOFAxOSEQvF2=	MnLUV2FPT0WU
COLO-679	MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NGn0RXZKSzVyPUGwMlQzQDVizszN	MoTSV2FPT0WU
CAS-1	MoTWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoXuTWM2OD1zMD60OlA5KM7:TR?=	NGCyUJJUSU6JRWK=
NCI-H2052	NI[3PHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXrZTHBZUUN3ME2xNE42OTB3IN88US=>	Mof4V2FPT0WU
NCI-H2452	MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MUjJR\|UxRTFyLk[xPFEh\|ryP	NEL5V3NUSU6JRWK=
SW13	NXjreo5rT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NWn4bmJTUUN3ME2xNE43Ozd2IN88US=>	MXrTRW5ITVJ?
HuP-T4	MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MnPWTWM2OD1zMD63NFY5KM7:TR?=	M1mxd3NCVkeHUh?=
UMC-11	M2nQO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnntTWM2OD1zMD65N\|c{KM7:TR?=	MX;TRW5ITVJ?
EGI-1	NUW1b4ZxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NH\WXnJKSzVyPUGwMlk1PTVizszN	M1Lt[HNCVkeHUh?=
JiyoyeP-2003	NYn4RmM3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4jUd2lEPTB;MUGuNFg6OiEQvF2=	M36xRnNCVkeHUh?=
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DoTc2-4510	NXnRc2xST3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NI\wbHdKSzVyPUGxMlE{QDlizszN	NH;pTo5USU6JRWK=
HLE	M{D4SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1nNU2lEPTB;MUGuNlEyQSEQvF2=	Mof4V2FPT0WU
SW626	M3[0ZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYPhNHNQUUN3ME2xNU4zQDh7IN88US=>	MXPTRW5ITVJ?
COR-L105	M3XWV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYDJR\|UxRTFzLkOyN\|ch\|ryP	M3LlVXNCVkeHUh?=
ES6	NIOzS5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NUj2fGpWUUN3ME2xNU42PzZizszN	NIS2ZXNUSU6JRWK=
SNU-449	M2HUVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYTJR\|UxRTFzLk[wO\|Ih\|ryP	NX32[Yh{W0GQR1XS
GR-ST	NVWwNYdLT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NH\INoNKSzVyPUGxMlYyQDFizszN	Mkm1V2FPT0WU
BL-41	MkDjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1HiOWlEPTB;MUGuO\|E4OyEQvF2=	M4HqeHNCVkeHUh?=
GB-1	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MmTITWM2OD1zMT63OlE6KM7:TR?=	MULTRW5ITVJ?
COLO-320-HSR	NH;mUHdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVHJR\|UxRTFzLki1NVkh\|ryP	MoDBV2FPT0WU
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NCI-H69	NHTHdGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3L3W2lEPTB;MUKuNFE{QSEQvF2=	M4[zfXNCVkeHUh?=
769-P	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1PXU2lEPTB;MUKuNFE6KM7:TR?=	MUTTRW5ITVJ?
A172	NXzRSmFWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NEjMPJFKSzVyPUGyMlEzODdizszN	MYXTRW5ITVJ?
CAL-27	NYLDcI1JT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUjJR\|UxRTF{LkGzOlkh\|ryP	Mo\vV2FPT0WU
NCI-H1437	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NE\yZnFKSzVyPUGyMlE1PDdizszN	MlnWV2FPT0WU
REH	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2K4OGlEPTB;MUKuNVU4OyEQvF2=	M3fUSHNCVkeHUh?=
KINGS-1	MkXZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MlnLTWM2OD1zMj6zOFIyKM7:TR?=	MX;TRW5ITVJ?
NCI-H1792	NV\MfGZnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXnJR\|UxRTF{LkO4OVEh\|ryP	NFHtZoFUSU6JRWK=
SK-MM-2	M3\lV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NUexW2xqUUN3ME2xNk41ODh5IN88US=>	NUXTVHpxW0GQR1XS
8505C	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M3znSWlEPTB;MUKuOlEzKM7:TR?=	Ml7oV2FPT0WU
HAL-01	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Ml;BTWM2OD1zMj62NVc1KM7:TR?=	NH;Eco1USU6JRWK=
NCI-H2141	M4rsbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmrRTWM2OD1zMj62OVgh\|ryP	M{LVNHNCVkeHUh?=
HCC1806	NVPPbJd{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3OxeGlEPTB;MUKuOlk2OiEQvF2=	M4LqWHNCVkeHUh?=
LU-134-A	M3zydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MkHkTWM2OD1zMj65N{DPxE1?	MmX6V2FPT0WU
HT	MkewS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYHlNY9sUUN3ME2xNk46PDN5IN88US=>	M1TiUHNCVkeHUh?=
OE33	MnXyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4jscmlEPTB;MUKuPVQ2PiEQvF2=	MlPzV2FPT0WU
ES4	NWDWSo84T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHXi[o9KSzVyPUGyMlk1QDdizszN	Mnr1V2FPT0WU
SW948	MmexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmHaTWM2OD1zMz6wNVMh\|ryP	NX6xWI54W0GQR1XS
LB2241-RCC	NIn3[nZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2PQcGlEPTB;MUOuNVQ3QSEQvF2=	NHfFWlJUSU6JRWK=
CCF-STTG1	M1:3R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1HFXmlEPTB;MUOuOFA{QSEQvF2=	M3jlbnNCVkeHUh?=
RPMI-8402	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NUfpRVc6UUN3ME2xN{42ODNzIN88US=>	MVTTRW5ITVJ?
DEL	NF7yfZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NInacItKSzVyPUGzMlU2ODNizszN	M4\0UHNCVkeHUh?=
NB5	M4HZfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M{\kbGlEPTB;MUOuOVUxOyEQvF2=	NHX2[GtUSU6JRWK=
NUGC-3	NUm2fIZXT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M3nUfWlEPTB;MUOuO\|Q2OyEQvF2=	Mn;qV2FPT0WU
CAL-72	Mk\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1zBPWlEPTB;MUSuNVkxPiEQvF2=	MUTTRW5ITVJ?
VMRC-RCZ	MnnWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4rkZ2lEPTB;MUSuNlM3KM7:TR?=	NYfrb3FwW0GQR1XS
YAPC	NEDZZoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWTJR\|UxRTF2LkK0NFch\|ryP	M2TSW3NCVkeHUh?=
ES5	NHuzUZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWLJR\|UxRTF2LkK1PVkh\|ryP	MV3TRW5ITVJ?
CAL-12T	M1PxNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MVXJR\|UxRTF2LkSzN\|Yh\|ryP	NETGSWlUSU6JRWK=
GAMG	MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NWDIT\|RxUUN3ME2xOE42PTd5IN88US=>	NFfp[GxUSU6JRWK=
BT-20	NISwZXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MlPvTWM2OD1zND65N\|g1KM7:TR?=	NXfDem5jW0GQR1XS
KALS-1	MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M3rLN2lEPTB;MUWuNFE2QCEQvF2=	MXfTRW5ITVJ?
LS-123	Mo\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MkPTTWM2OD1zNT6wNVY2KM7:TR?=	M4rx[3NCVkeHUh?=
LK-2	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MVTJR\|UxRTF3LkC4OlIh\|ryP	NF3sT5NUSU6JRWK=
NCI-H1770	M{jYeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnXaTWM2OD1zNT6yPFY5KM7:TR?=	NID3bnhUSU6JRWK=
MIA-PaCa-2	MlrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NH3BVGZKSzVyPUG1MlQyPjNizszN	MWLTRW5ITVJ?
DB	MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWrJR\|UxRTF3Lk[5OFEh\|ryP	MknsV2FPT0WU
Becker	NE\JWXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXfJR\|UxRTF3Lki5NlYh\|ryP	MnXZV2FPT0WU
HT-144	MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M4\oRmlEPTB;MUWuPVQ6PyEQvF2=	M4jjVXNCVkeHUh?=
NCI-H2405	MnPRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXjJR\|UxRTF4LkKyNVgh\|ryP	Mn\iV2FPT0WU
TK10	NFXCNZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MofpTWM2OD1zNj6zO\|QzKM7:TR?=	M3SwUXNCVkeHUh?=
THP-1	NF\yOGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVfwWndjUUN3ME2xOk41PjZ3IN88US=>	M1\wdXNCVkeHUh?=
LB373-MEL-D	MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NF7J[pFKSzVyPUG2MlYyOzhizszN	MUTTRW5ITVJ?
SJSA-1	MnrqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NWfyWmhpUUN3ME2xOk46OjF7IN88US=>	NGjXeYxUSU6JRWK=
EB2	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MonwTWM2OD1zNz63OFI3KM7:TR?=	MUDTRW5ITVJ?
MN-60	M3rWSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVu0PFNEUUN3ME2xO{44QTN4IN88US=>	NVnvTVVIW0GQR1XS
A253	M2e4eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIHr[XhKSzVyPUG3MlgzPSEQvF2=	MofDV2FPT0WU
CESS	MkfkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mm\STWM2OD1zNz65N\|I3KM7:TR?=	MWjTRW5ITVJ?
EW-11	M4fS[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NH\2SJVKSzVyPUG3Mlk6PThizszN	M1L2WHNCVkeHUh?=
TE-8	M3ztdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MmLxTWM2OD1zOD6wOlY6KM7:TR?=	M3zzcnNCVkeHUh?=
UACC-257	NHjk[ZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NILne4tKSzVyPUG4MlIxPjJizszN	NEmybWJUSU6JRWK=
NCI-H226	MkDlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4DVNmlEPTB;MUiuPFI6QSEQvF2=	M2ryV3NCVkeHUh?=
NCI-H748	NGnxbWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWTJR\|UxRTF6Lki1PFUh\|ryP	NGP1VXpUSU6JRWK=
NCI-H1299	NFL2VnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NH;He4lKSzVyPUG4Mlg6OThizszN	M{fFSXNCVkeHUh?=
IST-MEL1	MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NF3T[3ZKSzVyPUG5MlE4PTRizszN	M3vPO3NCVkeHUh?=
HCC1187	M3\QVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnXoTWM2OD1zOT6xO\|k3KM7:TR?=	MV;TRW5ITVJ?
HT-1376	MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXLpe41[UUN3ME2xPU4zODJ7IN88US=>	MW\TRW5ITVJ?
SK-MEL-2	MojoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NI\5XmpKSzVyPUG5MlIyPTVizszN	MXfTRW5ITVJ?
U031	NV3RcZBsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXTJR\|UxRTF7LkKyNVkh\|ryP	NV;6dGs6W0GQR1XS
NCI-H524	Ml3TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYLLS5BrUUN3ME2xPU42PzJ3IN88US=>	M3jDW3NCVkeHUh?=
KU812	M2Hoe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIfD[mpKSzVyPUG5MlU6PDRizszN	NWLXPHl7W0GQR1XS
NB10	NVXDW\|JYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHG4R5RKSzVyPUG5MlYzPjhizszN	M1jxNnNCVkeHUh?=
NOS-1	MmLCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoC1TWM2OD1{MD6xOVc4KM7:TR?=	M3XPSXNCVkeHUh?=
EW-7	M2W2TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NUPmWYNHUUN3ME2yNE4yPjJ6IN88US=>	MWHTRW5ITVJ?
Raji	NHzQWW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NGLnZ3BKSzVyPUKwMlI2PjhizszN	M{[0dnNCVkeHUh?=
LB2518-MEL	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NGjpfJBKSzVyPUKwMlM6PTNizszN	MmO1V2FPT0WU
PANC-10-05	NHH5V21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1v2e2lEPTB;MkCuOFYyOyEQvF2=	MmfwV2FPT0WU
MZ2-MEL	Mo\6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MlvSTWM2OD1{MD61PFE1KM7:TR?=	MX7TRW5ITVJ?
MFE-280	NHn5NoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MknWTWM2OD1{MT6zNVg5KM7:TR?=	NWTmWZJWW0GQR1XS
RKO	MoDSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGnR[mxKSzVyPUKxMlMzODJizszN	M{TDUXNCVkeHUh?=
KMOE-2	NVrLTIU4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NIDlZYVKSzVyPUKxMlMzQDhizszN	NFfUO4xUSU6JRWK=
K5	MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NXT4W\|FJUUN3ME2yNU4{QDl\|IN88US=>	MoDKV2FPT0WU
NCI-H64	NUXUOGsyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4rrWGlEPTB;MkGuOFc2PiEQvF2=	MmTsV2FPT0WU
K-562	M2O0WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVzPdGNEUUN3ME2yNU41QTdzIN88US=>	MUHTRW5ITVJ?
HCE-T	NV3seYI5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGXGUJVKSzVyPUKxMlUxQTRizszN	NGnEWYlUSU6JRWK=
COLO-792	NWHGPGNrT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NFzOO\|ZKSzVyPUKxMlU5OjdizszN	M1OwNXNCVkeHUh?=
PFSK-1	M{\NT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MXXJR\|UxRTJzLk[4N\|ch\|ryP	Mn3vV2FPT0WU
DOK	MnzkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGCxWVVKSzVyPUKxMlc3QDdizszN	MV\TRW5ITVJ?
NCI-H1882	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M1LwSGlEPTB;MkGuPFU6PiEQvF2=	NEjBdmNUSU6JRWK=
KNS-81-FD	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MULJR\|UxRTJzLki2N\|Eh\|ryP	NEnMdWpUSU6JRWK=
OCUB-M	NEjvTW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NGTR[JpKSzVyPUKxMlk3QDhizszN	NEXkfHlUSU6JRWK=
NCI-H1694	NVLtN\|k2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXjJR\|UxRTJzLkm4OlMh\|ryP	M1XoNXNCVkeHUh?=
LS-513	NEfMW5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NFnMRlNKSzVyPUKyMlA{PjdizszN	MXTTRW5ITVJ?
NCI-H2122	NF7uephIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXTJR\|UxRTJ{LkG2O\|ch\|ryP	MXjTRW5ITVJ?
IMR-5	M13oRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NVrtT2F7UUN3ME2yNk4zQDdizszN	NY\mcZF[W0GQR1XS
SNU-C2B	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Mmi2TWM2OD1{Mj62O\|Q3KM7:TR?=	NUWy[mczW0GQR1XS
A498	NILTTI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M3nibmlEPTB;MkKuPFE4PyEQvF2=	M3i1WnNCVkeHUh?=
NCI-H727	Mm\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NHfrRZdKSzVyPUKyMlg5OzZizszN	NV;aZ25jW0GQR1XS
SW1573	NV7FTJl5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXHJR\|UxRTJ\|LkC2OFYh\|ryP	NGnwSVlUSU6JRWK=
RO82-W-1	M2r0Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NUDVW3gzUUN3ME2yN{4zPTFzIN88US=>	M4PoO3NCVkeHUh?=
SKG-IIIa	NUj5OGJOT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGflTpNKSzVyPUKzMlM2PDZizszN	NXuwWZRFW0GQR1XS
MC-CAR	NI\kRnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4HqeWlEPTB;MkOuOVE5OyEQvF2=	M3TjdHNCVkeHUh?=
NCI-H446	NWi2c\|BFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NIjWfIdKSzVyPUKzMlYxQTNizszN	MkX4V2FPT0WU
PC-14	MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NX\vPZJTUUN3ME2yN{43PjJ\|IN88US=>	Mn\UV2FPT0WU
TGBC1TKB	MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NYKyXWJDUUN3ME2yN{44PDZzIN88US=>	NX\CfZpMW0GQR1XS
EFM-19	NEPndW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1\VVGlEPTB;MkSuNVg1PCEQvF2=	MYTTRW5ITVJ?
SK-N-DZ	MlqxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnTITWM2OD1{ND60PVc4KM7:TR?=	MlPmV2FPT0WU
NCI-H661	MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NF;YS3BKSzVyPUK0MlUzOTdizszN	NEPqU\|RUSU6JRWK=
SW1990	NHuzNnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MUDJR\|UxRTJ2LkW4PFMh\|ryP	NXWwS2psW0GQR1XS
SW684	NFj0c45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NIXuPHlKSzVyPUK0Mlc3OjRizszN	MX;TRW5ITVJ?
Ca-Ski	NUTJb5Q{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M{nwZWlEPTB;MkSuPVI{PyEQvF2=	NGrodVBUSU6JRWK=
TGW	MoPSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVPJR\|UxRTJ3LkKzN\|ch\|ryP	NV7WeHN1W0GQR1XS
CaR-1	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	Mlf5TWM2OD1{NT6zOVch\|ryP	NH3FXZJUSU6JRWK=
D-247MG	MlznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M1\XNmlEPTB;MkWuOFc1OyEQvF2=	MVrTRW5ITVJ?
CCRF-CEM	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NEH0[pdKSzVyPUK1Mlc1PTlizszN	NX;0eZhSW0GQR1XS
CAPAN-1	NYPRdWF5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MmTwTWM2OD1{NT63OVAyKM7:TR?=	NWTQTW17W0GQR1XS
CP50-MEL-B	NFrQVIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWHJR\|UxRTJ3Lkm5NFEh\|ryP	NUPIU2lJW0GQR1XS
FADU	MlrMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Ml\HTWM2OD1{Nj61NVUzKM7:TR?=	MWjTRW5ITVJ?
Daudi	NHHTRWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVXJR\|UxRTJ4LkWxOVgh\|ryP	MYLTRW5ITVJ?
U-87-MG	M2noPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NWnMNm5YUUN3ME2yOk42OzB3IN88US=>	NIXSTVlUSU6JRWK=
DSH1	MkTxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NWLv[GVnUUN3ME2yOk42PDB4IN88US=>	M3OxfnNCVkeHUh?=
KYSE-520	NFHOOotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NH;v[mFKSzVyPUK2MlU2PTNizszN	M{XySHNCVkeHUh?=
HuH-7	MorBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NYnPe4tjUUN3ME2yOk46ODh4IN88US=>	MXTTRW5ITVJ?
U-2-OS	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MYDJR\|UxRTJ5LkCyO\|Eh\|ryP	MV7TRW5ITVJ?
LU-99A	NGH2R2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1vtNWlEPTB;MkeuNVc2PCEQvF2=	NWHNcGE5W0GQR1XS
T98G	M4C1fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NYS1U2RMUUN3ME2yO{4yQTd\|IN88US=>	NV\STYtSW0GQR1XS
MZ7-mel	NEflWo5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NUn5UmtzUUN3ME2yO{42PTR6IN88US=>	NXW0U\|l2W0GQR1XS
SNU-C1	NH3CSXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NIPCXIFKSzVyPUK3MlY1QTFizszN	MoPXV2FPT0WU
MDA-MB-175-VII	M{f5O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NU\pZVE5UUN3ME2yO{43QTd3IN88US=>	M{fZcXNCVkeHUh?=
HuP-T3	NIrqeXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NVnDbHg6UUN3ME2yPE4xPDl3IN88US=>	MlTCV2FPT0WU
T-24	M4OyVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M4LlbGlEPTB;MkiuNVkzPSEQvF2=	MkLzV2FPT0WU
HDLM-2	Mk\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXrJR\|UxRTJ6LkK0OVkh\|ryP	NHHWXHBUSU6JRWK=
NCI-H1651	NX3j[Wl5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NHu2dnNKSzVyPUK4MlI2QTJizszN	NUXmWnBxW0GQR1XS
SK-N-AS	MnG5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MVHJR\|UxRTJ6LkOxO\|Eh\|ryP	M4XJcXNCVkeHUh?=
NY	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NUnJNIg1UUN3ME2yPE43PTd7IN88US=>	NYq3U5BPW0GQR1XS
D-283MED	MmTjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NUHGZ\|lSUUN3ME2yPE45PzB6IN88US=>	NH;SV4tUSU6JRWK=
KLE	NVXaWGU4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NXztd\|ljUUN3ME2yPE46QTB4IN88US=>	NWTpR3lXW0GQR1XS
NCI-H28	Mk\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MXTJR\|UxRTJ7LkCxNkDPxE1?	MnnPV2FPT0WU
TE-1	NF\uS\|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4LYW2lEPTB;MkmuNlE3PyEQvF2=	MXjTRW5ITVJ?
SK-MEL-24	NYrD[5ZNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYTJR\|UxRTJ7LkW0OlYh\|ryP	MULTRW5ITVJ?
CAL-54	M3O5Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	Mn7mTWM2OD1{OT62NFQ3KM7:TR?=	MmLZV2FPT0WU
A673	NFG0bGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NYXYbYVqUUN3ME2yPU44OzJizszN	M324PHNCVkeHUh?=
HEC-1	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NVjINZBNUUN3ME2zNE4xODV\|IN88US=>	NXX5enJyW0GQR1XS
LS-411N	NUDDWWJHT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MoLETWM2OD1\|MD6xOFc2KM7:TR?=	M{TWdnNCVkeHUh?=
SW962	NVfOR401T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NYTLd5RxUUN3ME2zNE4zPDd5IN88US=>	M3PTTXNCVkeHUh?=
OVCAR-8	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NUHGOItMUUN3ME2zNE43Pzl2IN88US=>	Mn3KV2FPT0WU
NCI-H630	NXrxNGc{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnjvTWM2OD1\|MD64PVU{KM7:TR?=	NVfNeotWW0GQR1XS
D-263MG	NGnrSW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NHrHRYdKSzVyPUOxMlA1OjRizszN	NFjQbmxUSU6JRWK=
NCI-H596	MlnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mn[4TWM2OD1\|MT6wOlIyKM7:TR?=	NGf1XG5USU6JRWK=
BB49-HNC	MnS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MWHJR\|UxRTNzLkGxNkDPxE1?	NEHmeIRUSU6JRWK=
KYSE-70	M2TKbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MYHJR\|UxRTNzLkOwNFgh\|ryP	NUe5bHZ5W0GQR1XS
LAN-6	M3HrN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIr4T5pKSzVyPUOxMlQ6QTJizszN	M4DzdXNCVkeHUh?=
NCI-H2228	NVW2UoZTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MV;JR\|UxRTNzLkW2NlUh\|ryP	MV;TRW5ITVJ?
SW620	M2joZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NHrvXIVKSzVyPUOxMlYzQDNizszN	M1fPNHNCVkeHUh?=
KM-H2	NV;Mco5kT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYLJR\|UxRTNzLkezNFYh\|ryP	MnTpV2FPT0WU
DJM-1	NH\kUWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NH76W2FKSzVyPUOyMlE{QDZizszN	M37IUnNCVkeHUh?=
SW48	NETsZmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M4jrc2lEPTB;M{KuN\|gzPSEQvF2=	M2nRXHNCVkeHUh?=
NCI-H1793	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MlTPTWM2OD1\|Mj62NVY{KM7:TR?=	M2jaV3NCVkeHUh?=
LU-165	M3TJXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MoThTWM2OD1\|Mz6wNFgh\|ryP	MYrTRW5ITVJ?
EHEB	NF\5NHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NIPWdI1KSzVyPUOzMlA1QTRizszN	NXnHbG5[W0GQR1XS
NCI-H441	Ml;3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MUjJR\|UxRTN\|LkKyN\|Uh\|ryP	NFjCNWpUSU6JRWK=
LOXIMVI	NVq3ZoJVT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NXftTYR7UUN3ME2zN{4{Pjd7IN88US=>	MYHTRW5ITVJ?
MC-IXC	MljLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M3fqWmlEPTB;M{OuOVY2PSEQvF2=	MlLVV2FPT0WU
NCI-H522	Mor6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MULJR\|UxRTN\|Lk[1OEDPxE1?	M3rne3NCVkeHUh?=
IA-LM	NInMfpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Mk\nTWM2OD1\|Mz62O\|Q3KM7:TR?=	MV\TRW5ITVJ?
NCI-H1417	M3HGPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MorHTWM2OD1\|Mz65OVg2KM7:TR?=	MWDTRW5ITVJ?
HCC2218	M4PLemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NH;BUXpKSzVyPUO1MlIyQDVizszN	MXLTRW5ITVJ?
HC-1	M1jPfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1HDW2lEPTB;M{WuOFAzPCEQvF2=	MmfnV2FPT0WU
HH	NFHnVGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M1XYbGlEPTB;M{WuOFE1OSEQvF2=	MUHTRW5ITVJ?
EFE-184	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MV\JR\|UxRTN3Lk[4Nlkh\|ryP	Ml3MV2FPT0WU
NCI-H1355	M{Oxd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MWHJR\|UxRTN3Lke3NVgh\|ryP	NXLsPZVHW0GQR1XS
BV-173	Mo\TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NG\OXXRKSzVyPUO1MlgzPjRizszN	M4XhU3NCVkeHUh?=
NEC8	M2Xs[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MnziTWM2OD1\|Nj60PVI1KM7:TR?=	MkS5V2FPT0WU
SW1463	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NG\zOJNKSzVyPUO2MlY2PjZizszN	MWLTRW5ITVJ?
KYSE-140	NFnDeJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NWHDdZR6UUN3ME2zOk44Ojl6IN88US=>	NH[w[IdUSU6JRWK=
no-11	MoS1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGLpclFKSzVyPUO2Mlg2OzZizszN	MW\TRW5ITVJ?
HCC1937	MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NInZU3JKSzVyPUO3MlAyPTRizszN	NVPUWFZFW0GQR1XS
LNCaP-Clone-FGC	NVHhXGliT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M33uOWlEPTB;M{euNVkxOyEQvF2=	NV3jfIJRW0GQR1XS
KARPAS-422	MmjJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MWfJR\|UxRTN5LkS0N\|Eh\|ryP	NYfmNJQ6W0GQR1XS
RCM-1	NGjkT49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NXrNT3Z[UUN3ME2zO{42OzV6IN88US=>	NHnSRplUSU6JRWK=
A375	MnWxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MoLLTWM2OD1\|Nz63OlQ4KM7:TR?=	NX\tOYV[W0GQR1XS
TGBC24TKB	NXvaSlJmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MUXJR\|UxRTN6LkCyN\|kh\|ryP	NX3Ico5rW0GQR1XS
MDA-MB-453	NUDhfYhDT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MXPJR\|UxRTN7LkCyNVgh\|ryP	MV;TRW5ITVJ?
Capan-2	NFv6VndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVfJR\|UxRTN7LkC1NFkh\|ryP	MlPWV2FPT0WU
SW756	M4rBfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NH;HSmtKSzVyPUO5MlUxQTFizszN	M3G4XXNCVkeHUh?=
KU-19-19	NV[zZ\|B4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M1vYW2lEPTB;M{muOlI5OiEQvF2=	M37iO3NCVkeHUh?=
NCI-H2170	NYPF[4s2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGfWTWNKSzVyPUO5Mlk6PzdizszN	NETaVGpUSU6JRWK=
COLO-678	Mo[zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Moq1TWM2OD12MD61PVUh\|ryP	NX[wToRQW0GQR1XS
PF-382	NY\jRlVjT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MWfJR\|UxRTRyLke0PFch\|ryP	NEjwRoNUSU6JRWK=
OAW-42	MkflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	NGj0fYJKSzVyPUSyMlI6PDJizszN	NV;zZ4hGW0GQR1XS
LB996-RCC	M3r6S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MkDMTWM2OD12Mj64NFA5KM7:TR?=	NVi4NFFrW0GQR1XS
SAS	M2XPc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1S0cmlEPTB;NEOuOFI5QCEQvF2=	NF7r[4tUSU6JRWK=
MRK-nu-1	NFPYb3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NFqx[GlKSzVyPUS0Mlc1OTRizszN	NWHJTph1W0GQR1XS
EoL-1-cell	NEPWZ4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	NGPVeopKSzVyPUS0MlkyOzZizszN	NIn6VlhUSU6JRWK=
NCI-H2342	NV60SZpYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	NGHHVmtKSzVyPUS1MlEyOTdizszN	NF72S4ZUSU6JRWK=
NCI-H1703	M1n4OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NIXrXmlKSzVyPUS2MlA2QTJizszN	NWrvRphMW0GQR1XS
NCI-H187	MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M2P2e2lEPTB;NE[uNVg3QSEQvF2=	MYTTRW5ITVJ?
CP66-MEL	NWXCVXpDT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MYjJR\|UxRTR4LkK3PFkh\|ryP	M2\3TXNCVkeHUh?=
HCC1569	MoGxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MljkTWM2OD12Nj61PVE4KM7:TR?=	MlvhV2FPT0WU
BL-70	NEDRSlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	Mkf3TWM2OD12Nj63O\|M4KM7:TR?=	NHXxUIFUSU6JRWK=
Saos-2	MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWTJR\|UxRTR5LkOxNlMh\|ryP	Mkn0V2FPT0WU
LC-1F	NU\PfWR6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MnzrTWM2OD12Nz62NVA2KM7:TR?=	M3Hs[nNCVkeHUh?=
KY821	MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MkTwTWM2OD12Nz62OFM1KM7:TR?=	NVPRflZ6W0GQR1XS
PSN1	MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MV\JR\|UxRTR6LkG0NFEh\|ryP	M2PuR3NCVkeHUh?=
RT4	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	NIe1XoJKSzVyPUS4Mlg{PzdizszN	NIXBd5dUSU6JRWK=
LS-1034	M{fUcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NX32PZZkUUN3ME20PE45QTV2IN88US=>	MorxV2FPT0WU
NCI-H1395	MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M{jGeGlEPTB;NEmuNFQ6OiEQvF2=	MWrTRW5ITVJ?
EKVX	M2rG[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M1;ieGlEPTB;NEmuOlc{OSEQvF2=	MV3TRW5ITVJ?
IST-MES1	Ml22S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M4rqT2lEPTB;NEmuPFk1PCEQvF2=	NHn5dmlUSU6JRWK=

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	p-FAK / FAK / p-Talin / Talin ; PubMed: 26530902 Cancer Res Dose response of PF-562271 on the phosphorylation of FAK-Y397 or Talin-S425 in PC3-mm2 cells. p-Src / Src / p-paxillin / Paxillin / ICAM-1 ; PubMed: 29417941 Acta Pharmacol Sin MDA-MB-231 cells transfected with FAK-specific siRNAs or treated for 12 h with PF-562271 at the indicated concentrations were subjected to immunoblotting with indicated antibodies.	26530902 29417941
Immunofluorescence	p-FAK; PubMed: 26530902 Cancer Res Immunostaining of PC3-mm2 cells showed that phosphorylated FAK is localized at focal adhesions (inset).	26530902
Growth inhibition assay	Cell viability; PubMed: 28953264 Nutrients MTT assay showed inhibition of cell proliferation and viability in HCT116 (B) and SW480 (D) cell lines treated with resveratrol and/or different concentrations of FAK-Inhibitor (PF-562271: 0.01, 0.1, 1, and 10 µM) cultured in monolayer for 12 h. Data shown are representative of three independent sets of experiments. Values were compared with the control and statistically significant values with p < 0.05 are designated by an asterisk () and p < 0.01 are designated by two asterisks (*).	28953264

体内研究

在携带U87MG的小鼠中PF-562271 (< 33 mg/kg 口服)抑制肿瘤中FAK磷酸化并具有时间和剂量依赖特性。PF-562271 (50 mg/kg, 口服，一天两次)对BxPc3异种移植小鼠中肿瘤生长抑制率为86% ，对PC3-M异种移植小鼠中肿瘤生长抑制率为45%。PF-562271 (25mg/kg, 一天两次)处理的携带H125肺部异种移植肿瘤凋亡率提高2倍^[1]。 PF-562271 (33 mg/kg,口服)24小时后抑制小鼠中肿瘤细胞的广泛运动。PF-562271 (33 mg/kg, 口服)导致小鼠中E-cadherin动力学的改变，这与减弱的E-cadherin依赖的整体细胞运动有关 ^[3]。在皮下局部异种移植PC3M-luc-C6的小鼠模型中 PF-562271 (25 mg/kg, 口服，一天两次)导致肿瘤生长率62%的抑制^[4]。在胫骨植入MDA-MB-231细胞的大鼠中PF-562271 (5mg/kg, 口服)导致骨钙素和松质骨参数显著而相似的增加同时导致肿瘤生长速度和骨愈合信号的下降^[5]。

动物实验：^[1]	- 合并 Animal Models: 携带BxPc3或 PC3-M异种移植的无胸腺雌性小鼠 Dosages: 50 mg/kg Administration: 填喂给药 (Only for Reference)

参考文献

- 合并

溶解度 (25°C)

体外	DMSO	100 mg/mL warmed (197.04 mM)
	Water	Insoluble
	Ethanol	Insoluble
体内	从左到右依次将纯溶剂加入产品，现配现用(数据来自Selleck实验检测而非文献)： 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O	5 mg/ml

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据 Download PF-562271 SDF

分子量	507.49
化学式	C₂₁H₂₀F₃N₇O₃S
CAS号	717907-75-0
储存条件	3年-20°C 粉状 2年-80°C 溶于溶剂
别名	N/A

动物体内配方计算器 (澄清溶液)

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）

% DMSO+ % + % Tween 80+ % ddH₂O

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

质量

浓度

体积

分子量
=

×

×

*在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入输出 )

C1

V1

C2

V2
×

=

×

在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量计算器

通过输入化合物的化学式来计算其分子量：

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量	浓度	体积	分子量
=	×	×
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

研究领域

产品类型

定制您的化合物库

PF-562271

客户使用Selleck生产的PF-562271发表文献87篇：

产品安全说明书

FAK抑制剂选择性比较

生物活性

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

参考文献

溶解度 (25°C)

化学数据 Download PF-562271 SDF

动物体内配方计算器 (澄清溶液)

计算器

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

稀释计算器

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

连续稀释计算器方程

连续稀释

计算结果

分子量计算器

总分子量：g/mol

摩尔浓度计算器

技术支持

FAK Signaling Pathway Map

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