• Menin-MLL interaction
  • WDR5-MLL interaction

WDR5-MLL-interaction 抑制剂 | 拮抗剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S7265 MM-102 MM-102 (HMTase Inhibitor IX) is a high-affinity peptidomimetic inhibitor of the WDR5/MLL1 protein-protein interaction, which bind to WDR5 with Ki < 1 nM and IC50 =2.4nM. Pan WDR5, IC50: 2.4 nM
S7833 OICR-9429 OICR-9429 is a potent antagonist of the interaction of WDR5 with peptide regions of MLL and Histone 3 and reduces viability of acute myeloid leukemia cells in vitro. It binds to WDR5 with high affinity (KD = 93 ± 28 nM. Pan WDR5, Kd: 93 nM
S2184 WDR5-0103 WDR5-0103 (WD-Repeat Protein 5-0103) is a small-molecule antagonist of WDR5 (WD40 repeat protein 5) with Kd of 450 nM. Pan WDR5, Kd: 450 nM; WDR5-MLL interaction, :
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