Immunology & Inflammation related
Immunology & Inflammation related产品
- 所有产品(470)
- Immunology & Inflammation related抑制剂 (115)
- Immunology & Inflammation related抗体 (11)
- Immunology & Inflammation related激活剂 (1)
- Immunology & Inflammation related拮抗剂 (1)
- Immunology & Inflammation related激动剂 (2)
- Immunology & Inflammation related调节剂 (21)
| 目录号 | 产品名 | 产品描述 | 文献引用 | 实验数据 |
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| S2286 | Cyclosporin A | Cyclosporin A, 一种非极性环寡肽，是一种免疫抑制剂，与亲环素结合，随后抑制calcineurin，无细胞试验中IC50为7 nM，广泛用于预防器官移植反应中的排斥反应,并已用于在灌注的3D近端小管模型上测试其毒性作用。 |
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| S8141 | Cl-amidine | Cl-amidine是一种不可逆地泛 peptidylarginine deiminase (PAD) 抑制剂，对PAD4、PAD1和PAD3的IC50值分别为5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM。Cl-amidine 可诱导凋亡。 | ||
| S7434 | TAPI-1 | TAPI-1 是一种ADAM17/TACE抑制剂, 其对细胞因子受体有抑制作用。TAPI-1 也是 Matrix Metalloproteinase (MMP) 的抑制剂。 |
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| S3032 | Bindarit | Bindarit是天然化合物，具有特定抗炎活性，因为选择性抑制炎症趋化因子亚家族，包括单核细胞趋化蛋白MCP-1/CCL2, MCP-3/CCL7, 和 MCP-2/CCL8。 |
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| S4169 | Teriflunomide | Teriflunomide (A77 1726, HMR-1726) 是Leflunomide的活性代谢物，通过抑制酶二氢乳清酸脱氢酶，从而抑制嘧啶从头合成，作为一种免疫调节剂。 |
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| S1576 | Sulfasalazine | Sulfasalazine是一种磺胺剂，是Mesalazine的衍生物，主要用作抗炎剂。Sulfasalazine 是一种有效的、特异性的 nuclear factor kappa B (NF-κB)、TGF-β 和 COX-2 的抑制剂。Sulfasalazine 可诱导铁死亡、凋亡和自噬。 | ||
| S1737 | Prednisolone | Prednisolone是一种人工合成的糖皮质激素，具有抗炎和免疫调节特性。 |
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| A2001 | Ipilimumab (anti-CTLA-4) | Ipilimumab (anti-CTLA-4)是一种免疫调节单克隆抗体，靶向细胞表面抗原CTLA-4；也是一种免疫检查点抑制剂；MW：148 KD。 |
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| S5004 | Pimecrolimus | Pimecrolimus (Elidel,ASM 981,SDZ-ASM 981)是一种抑免蛋白配体, 可以特异地与胞质受体macrophilin-12结合；是钙调蛋白抑制剂。 |
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| S2910 | Tempol | Tempol (4-Hydroxy-TEMPO) 是一种超氧化物清除剂，具有神经保护，抗炎症和镇痛效果。Phase 2 | ||
| S1439 | Tranilast | Tranilast是一种抗过敏化合物。 |
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| S3648 | Amlexanox | Amlexanox是一种抗炎抗过敏免疫调节剂，也是蛋白激酶 TBK1 和 IKK-ε 的抑制剂。 | ||
| A2102 | Anti-mouse CD8α-InVivo | Anti-mouse CD8α(克隆号：2.43)可与小鼠CD8α结合反应。CD8是一种穿膜糖蛋白，是T细胞受体（TCR）的协同受体。有助于后续与抗原呈递细胞的交流通讯。 |
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| S2359 | Sinomenine | Sinomenine (Cucoline, Kukoline) 是一种传统中草药，用于治疗风湿病和关节炎。 |
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| S1514 | Cyclosporine | Cyclosporine是一种钙调酶抑制剂，用作免疫抑制剂药物来组织器官移植中的免疫排斥。 | ||
| A2009 | Rituximab (anti-CD20) | Rituximab (anti-CD20)是嵌合的anti-CD20单克隆抗体，与B细胞上的CD20抗原结合，结合亲和力为5 nM。MW: 143.86 KD。 | ||
| S8301 | Ossirene (AS101) | Ossirene (AS101)，一种有效的体内体外免疫调节剂，是新型的IL-1beta转化酶的抑制剂。 | ||
| S5804 | N-Acetylcysteine amide | N-acetylcysteine amide是一种能穿透细胞膜的抗氧化剂，具有消炎活性，能够调节NF-κB的激活、HIF-1α和ROS。 | ||
| S2413 | Geniposidic acid | Geniposidic acid 是一种环烯醚萜类糖苷，用于治疗炎症，黄疸以及肝病。 | ||
| S1654 | Phenylbutazone | Phenylbutazone (Butazolidine) 是一种非甾体抗炎剂，用于治疗慢性疼痛，包括关节炎的症状。 | ||
| S8660 | GI254023X | GI254023X (GI 4023, SRI028594)是ADAM10的选择性抑制剂，对ADAM10的选择性是对ADAM17的100倍。它对重组型ADAM10和ADAM17的IC50值分别为5.3 nM和541 nM。GI254023X能够抑制MMP9。 | ||
| S2350 | Rutin | Rutin (Rutoside)是在许多植物中发现的一种黄酮苷，包括Buckwheat; Tobacco; Forsythia; Hydrangea; Viola, 等。 | ||
| S1591 | Bestatin (Ubenimex) | Bestatin (Ubenimex)是竞争性氨肽酶B抑制剂，作用于K562细胞，IC50为100 mg/ml。 |
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| S1622 | Prednisone | Prednisone是一种人工合成的皮质类固醇剂，是特别有效的免疫抑制剂的化合物。 | ||
| S5501 | Hydrocortisone acetate | Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. | ||
| S8760 | Iberdomide (CC220) | Iberdomide (CC-220) 是一种新型口服免疫调节化合物，靶向cereblon（cereblon是CRL4CRBN E3泛素连接酶复合体的一部分），IC50为60 nM。Iberdomide (CC-220) 可诱导凋亡并具有抗肿瘤和免疫刺激的活性。 | ||
| S7448 | CORM-3 | CORM-3 是一种一氧化碳的释放分子，具有抗炎和保护心脏的作用。 | ||
| S1211 | Imiquimod | Imiquimod是新型合成的药剂，具有免疫反应修饰活性。 | ||
| S5260 | ATP | ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) 是一种多功能的三磷酸核苷，是免疫和炎症反应中重要的内源性信号分子。 | ||
| S5318 | Acacetin | Acacetin (Linarigenin, 5,7-dihydroxy-4'-methoxyflavone, 4'-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. | ||
| S9311 | Germacrone | Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities. | ||
| S2338 | Oxymatrine | Oxymatrine (Matrine N-oxide)是一种从Sophora flavescens的根部分离的喹唑啉生物碱，具有抗炎症、抗纤维化、抗肿瘤活性，抑制iNOS表达和TGF-β/Smad通路。被用于治疗病毒性肝炎、癌症、病毒性心肌炎、胃肠出血和皮肤疾病。 | ||
| S2383 | Gastrodin | Gastrodin (Gastrodine) 是一种多元酚，是4-羟基苄醇的葡糖苷。 | ||
| S7892 | Avadomide (CC-122) | Avadomide (CC-122)，一种新型的多效性修饰剂化合物，在弥漫性大B细胞淋巴瘤（DLBCL）中具有抗肿瘤、免疫调节活性。其分子靶标为cereblon (CRBN)，CRBN是E3泛素化连接酶复合体CRL4CRBN的底物受体。 | ||
| S8291 | Atractylenolide I | Atractylenolide I 是A. macrocephala根茎的主要类倍半萜烯类化合物。具有广谱的药理活性，如抗炎、促消化、抗氧化作用。 | ||
| S7516 | Y-320 | Y-320 是一种口服有效的 immunomodulator, 它通过 CD4 T 细胞刺激 IL-15 从而抑制IL-17的产生，其IC50为20到60 nM。 | ||
| S1733 | Methylprednisolone | Methylprednisolone是一种人工合成的皮质类固醇，具有抗炎和免疫调节特性。Methylprednisolone 可激活 ACE2 和降低 IL-6 水平，这样来改善严重或危重的 COVID-19。Methylprednisolone 可显著地减少自噬和凋亡。 |
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| S5500 | Amodiaquine hydrochloride | Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. | ||
| S3758 | Sinomenine hydrochloride | Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent. | ||
| S9430 | Tomatidine Hydrochloride | Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages. | ||
| S4761 | Thymoquinone | Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects. | ||
| S2787 | Laquinimod | Laquinimod (ABR-215062, LAQ)是有效的免疫调节剂。Phase 3。 | ||
| S1681 | Mesalazine (5-ASA) | Mesalazine (5-ASA)是一种抗炎化合物。 | ||
| S3608 | Demethylzeylasteral (T-96) | Demethylzeylasteral (T-96)是从Tripterygium wilfordii Hook F.中分离出的活性成分，能够抑制UDP-glucuronosyltransferase (UGT)的亚型UGT1A6和UGT2B7，具有免疫抑制活性。 | ||
| S3614 | Lupeol | Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) 是一种显著的白桦脂酸型三萜烯，存在于植物、真菌和动物中，具有抗癌、抗原生动物、化学预防、消炎作用。 | ||
| S4268 | Flufenamic acid | Flufenamic acid 是一种非甾体抗炎药物，离子通道调节剂。 | ||
| S3824 | Quercitrin | Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities. | ||
| S5648 | Iguratimod | Iguratimod (T-614) is a small molecule compound with anti-inflammatory and immunomodulatory actions and used for the treatment of rheumatoid arthritis. | ||
| S9038 | Calycosin | Calycosin (3'-Hydroxyformononetin), an isoflavonoid, is the major active component in Radix Astragali. It shows antitumor, anti-inflammatory, neuroprotective and pro-angiogenesis effects. | ||
| S9032 | Sanguinarine | Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation. | ||
| S8097 | C-DIM12 | C-DIM12是Nurr1的激活剂，刺激膀胱癌细胞和肿瘤中Nurr1所介导的细胞凋亡、抑制胶质细胞中对NF-κB依赖的基因表达。 | ||
| S9131 | Punicalagin | Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects. | ||
| S6812 | Z-Guggulsterone | Z-Guggulsterone 是阿育吠陀药用植物 Commiphora mukul 的一种成分，在体外和体内抑制血管生成。Z-Guggulsterone 在小胶质细胞中具有抗炎作用。Z-Guggulsterone 通过内在的线粒体依赖性途径诱导胃癌细胞凋亡。 | ||
| S5517 | Fenamic acid | Fenamic acid (N-Phenylanthranilic acid, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Diphenylamine-2-carboxylic acid) serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. | ||
| A2028 | Tiragolumab (anti-TIGIT) | Tiragolumab (anti-TIGIT) (RG6058, MTIG7192A) 是一种人源化 IgG1/kappa 单克隆抗体，可与 TIGIT 结合以防止其与其配体 PVR (CD155) 相互作用。 | ||
| S1829 | Pranlukast | Pranlukast (ONO-1078,ono-rs-411) 是一种选择性白三烯受体拮抗剂。 | ||
| S3062 | Diclofenac Potassium | Diclofenac potassium (CGP-45840B) 是一种非类固醇消炎药，用于减轻炎症和某些状况下的止痛药。 | ||
| S7515 | VGX-1027 | VGX-1027 (GIT 27) 是一种口服有效的免疫调节剂。 Phase 1。 | ||
| S1823 | Fenoprofen Calcium | Fenoprofen Calcium是一种非甾体类，抗炎，抗关节炎药剂。 | ||
| S2411 | Geniposide | Geniposide是Gardenia jasminoides Ellis果实分离得到的一种环烯醚萜苷类。 | ||
| S5737 | Diclofenac Epolamine | Diclofenac Epolamine (DHEP, DIEP, diclofenac hydroxyethylpyrrolidine) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. | ||
| S5157 | Thymol | Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro. | ||
| S5674 | Lodoxamide Tromethamine | Lodoxamide Tromethamine (Alomide, Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. | ||
| S9213 | Jujuboside A | Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis. | ||
| S6239 | PMX-53 | PMX-53 是一种有效的CD88 (C5aR)拮抗剂，抑制C5a诱导的中性粒细胞髓过氧化物酶释放和趋化性，IC50值分别为22 nM 和 75 nM。PMX-53也是Mas-related gene 2 (MrgX2)的激动剂。 | ||
| S9043 | 6-Shogaol | 6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties. | ||
| S9247 | Isoliensinine | Isoliensinine is an alkaloid produced by the edible plant Nelumbo nucifera. It possesses anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities. | ||
| S5661 | Tiaprofenic acid | Tiaprofenic acid (Tiaprofensaeure, Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain. | ||
| S2387 | Lappaconite HBr | Lappaconite HBr是从Aconitum sinomontanum Nakai 提取的一种生物碱，具有抗炎作用。 | ||
| S6185 | Arachidonic acid | Arachidonic acid (Arachidonate)是非饱和必需脂肪酸，在动物和人类肝脏、脑部和腺器官脂肪中都有发现。它是前列腺素、凝血噁烷和白细胞三烯的生物合成的前体化合物。 | ||
| S9289 | Astragalin | Astragalin (kaempferol-3-glucoside, Kaempferol 3-O-glucoside, Kaempferol 3-D-glucoside), a flavonoid from leaves of persimmon and green tea seeds, has anti-tumor, anti-inflammatory and anti-oxidant activities. | ||
| S9290 | Linarin | Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects. | ||
| S9293 | Isoliquiritin | Isoliquiritin (Neoisoliquritin) is a flavonoid glycoside compound from licorice possessing a broad spectrum of pharmacological activities including antioxidant, anti-inflammatory, and anti-depression activities. | ||
| S4170 | Coumarin | Coumarin是植物化学成分，具有肝毒性和致癌性。 | ||
| S9304 | Platycodin D | Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anti-inflammatory, anti-allergic, cholesterol-lowering and neuroprotective properties. | ||
| S2400 | Rheic Acid | Rhein (Monorhein, NSC 38629, Rheinic) 是Rhubarb的组成部分，是从Rheum coreanum Nakai新鲜根茎分离得到的，具有抗炎和抗肿瘤活性。Rhein 是一种FTO (mRNA N6-methyladenine demethylase)的抑制剂，并且还可抑制 AlkB repair enzymes。 | ||
| S6322 | Pipecolic acid | Pipecolic acid (piperidine-2-carboxylic acid)是人生理体液如尿液、血浆和脑脊液中赖氨酸的代谢物，在植物和人体中是重要的免疫调节剂。 | ||
| S3675 | Umbelliferone | Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities. | ||
| S3668 | Thymopentin | Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells. | ||
| S9055 | Salvianolic acid A | Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck. | ||
| S9052 | Auraptene | Auraptene (7-geranyloxycoumarin)是源自柑橘类植物的天然香豆素，具有重要的药理特性，包括抗癌，抗炎，抗幽门螺杆菌，抗原毒性和神经保护作用。Auraptene 可抑制 matrix metalloproteinase 2 (MMP-2) 以及关键的炎症介质，包括 IL-6、IL-8 和 chemokine (C-C motif) ligand-5(CCL5)。 | ||
| S9057 | Sinigrin | Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects. | ||
| S3027 | Fenoprofen calcium hydrate | Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate)是一种非甾类抗炎症药物(NSAID)。 | ||
| S9035 | Isovitexin | Isovitexin (saponaretin, Apigenin-6-C-glucoside), an active component of many traditional Chinese medicines, has various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on. | ||
| S3871 | Muscone | Muscone (3-Methylcyclopentadecanone, Methylexaltone)是一种增香成分，一种有机化合物，是麝香气味的主要来源，也是一种有效的消炎剂。Muscone 可显著地下调LPDM诱导的炎症细胞因子水平，并抑制BMDM中 NF-κB 和 NLRP3 炎性小体的活化。Muscone 还可以显著地降低炎性细胞因子inflammatory cytokines (IL-1β, TNF-α, IL-6) 的水平。 | ||
| S9074 | Buddlejasaponin IVb | Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells. | ||
| S3877 | Lysionotin | Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities. | ||
| S9411 | Liensinine | Liensinine, an important functional compound in lotus seeds, has anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities. | ||
| S9105 | Ginsenoside CK | Ginsenoside CK is a ginsenoside found in Panax species and has a role as a plant metabolite, an antineoplastic agent, a hepatoprotective agent, an anti-allergic agent and an anti-inflammatory agent. | ||
| S5083 | Lentinan | Lentinan (A823605, Bromoduline)，分离纯化自香菇子实体水煮提取物，是一种真菌多糖免疫调制剂，具有抗肿瘤活性。 | ||
| S9115 | Wogonoside | Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. | ||
| S3813 | Bakuchiol | Bakuchiol ((S)-(+)-Bakuchiol) is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities. | ||
| S3745 | Balsalazide disodium | Balsalazide Disodium 是balsalazide的二钠盐形式，balsalazide是一种口服的对氨水杨酸钠前体药物，在结肠中被酶解、产生抗炎性的美沙拉秦（mesalazine）。Balsalazide Disodium 通过调节 IL-6/STAT3 途径抑制结肠炎相关的癌变。 | ||
| S9127 | Carnosol | Carnosol is a naturally occurring phenolic diterpene found in rosemary. It has anti-oxidant, anti-inflammatory and anti-cancer activities. | ||
| S9502 | Madecassic acid | Madecassic acid (Brahmic acid) 是最早从积雪草中分离的天然三萜，具有多种消炎和抗糖尿病作用，阻断巨噬细胞中的 NF-κB 活化并导致 iNOS、COX-2、TNF-alpha、IL-1beta 和 IL-6 抑制。 | ||
| S9474 | Acetylharpagide | Acetylharpagide是来源于金疮小草（Ajuga decumbens）的一种单体化合物，广泛用于治疗传染性和炎症性疾病。 | ||
| S9146 | Anwuligan | Anwuligan (Macelignan), a natural compound isolated from Myristica fragrans Houtt, has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities. | ||
| E0206 | Ginkgetin | Ginkgetin 是一种来自银杏叶的双黄酮，具有抗癌、抗炎、抗微生物、抗脂肪生成和神经保护作用。 | ||
| S6476 | Eicosapentaenoic Acid (EPA) | Eicosapentaenoic acid (EPA)是omega-3多不饱和脂肪酸，具有消炎活性，在鱼和鱼肝油（包括三文鱼、鳕鱼和磷虾油）中出现。 | ||
| S5686 | Tryptanthrin | Tryptanthrin is a natural alkaloidal compound having basic indoloquinazoline moiety. It has broad spectrum of biological activities including anticancer activity, anti-inflammatory, antiprotozoal, antiallergic, antioxidant, and antimicrobial. | ||
| S5869 | Cortisone | Cortisone是一种孕烷甾类激素，是身体应对压力应激时释放的主要物质。它能抑制免疫系统，从而减少炎症反应和炎性疼痛、伤处肿胀。 | ||
| S1939 | Levamisole hydrochloride | Levamisole，也被称作(-)-Tetramisole，是一种驱虫药物，已经尝试用于治疗风湿性疾病通过增加巨噬细胞的趋化性和T-淋巴细胞的功能显著恢复免疫应答。 | ||
| S1679 | Flurbiprofen | Flurbiprofen 是一种苯基烷酸衍生物，是非甾体类抗炎药（NSAIDs）。 | ||
| S2512 | Tenoxicam | Tenoxicam(Ro-12-0068)是一种有效的自由基清除剂，IC50为56.7 μM。 | ||
| S4098 | Halcinonide | Halcinonide(SQ-18566)是一种高效的皮质类固醇，用作局部制剂，作为抗炎剂。 | ||
| E0212 | Cornuside | Cornuside 是一种从 Cornus officinalis SIEB. et ZUCC 果实中分离出来的双环烯醚萜苷化合物。Cornuside 通过抑制 RAW 264.7 巨噬细胞中的 NF-κB 活化来抑制脂多糖诱导的炎症介质。Cornuside 减弱大鼠皮质神经元的细胞凋亡。 | ||
| S5459 | Aucubin | Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages. | ||
| S3622 | Diammonium Glycyrrhizinate | Diammonium glycyrrhizinate (DG)是一种传统的中草药，从甘草中提取纯化而来。它具有抗炎活性，对生物氧化具有抗性、对膜具有保护性。DG通过抑制NF-κB、TNF-α和细胞间黏附分子1来减少炎症损伤。 | ||
| S5457 | Curculigoside | Curculigoside (Curculigoside A), a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects. | ||
| E0215 | Isorhapontigenin | Isorhapontigenin (ISOR) ，从 Belamcanda chinensis 中分离出来，是二苯乙烯的衍生物。Isorhapontigenin 具有有效的抗氧化活性。Isorhapontigenin 抑制白介素 1β 诱导的大鼠软骨细胞炎症和软骨基质损伤。 | ||
| E3524 | Oregano Extract | Oregano Extract是从牛至草Origanum vulgare中提取的，具有保护心血管、预防癌症和降低胃肠道炎症的功效。 | ||
| S3982 | Batyl alcohol | Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent. | ||
| S5471 | Monotropein | Monotropein, an iridoids glycoside isolated from the roots of Morinda officinalis How, has been demonstrated to exhibit anti-inflammatory activity. | ||
| S5361 | Bendazac | Bendazac (bendazolic acid, AF-983) is a non-steroidal anti-inflammatory drug that delays the cataractogenic process. It may act by preventing protein denaturation. | ||
| E0150 | Carrageenan | Carrageenan (kappa-Carrageenan) 是一种从食用红海藻中提取的天然碳水化合物（多糖）。Carrageenan具有抗凝活性、抗血栓形成活性、抗病毒活性、抗肿瘤活性和免疫调节活性。 | ||
| E0216 | Hinokiflavone | Hinokiflavone，从 Selaginella P. Beauv、Juniperus phoenicea 和 Rhus succedanea 中分离得到，具有优异的药理活性，包括抗炎、抗氧化和抗肿瘤活性。Hinokiflavone 通过 EMT 信号通路诱导细胞凋亡并抑制乳腺癌细胞的迁移。 | ||
| S5871 | Trans-Tranilast | Trans-Tranilast是抗过敏药，用于治疗支气管哮喘、过敏性鼻炎和过敏性皮肤炎。 | ||
| S4842 | Balsalazide | Balsalazide (Colazal, Giazo) 是一种氨基水杨酸盐和口服活性的前药，在结肠中被酶解产生具有抗炎效果的mesalazine。Balsalazide 通过调节 IL-6/STAT3 途径来抑制溃疡性结肠炎相关癌变。 | ||
| S5458 | Verbascoside | Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant. | ||
| E3816 | Emilia Sonchifolia Extract | Emilia Sonchifolia Extract 从一点红Emilia sonchifolia中提取，它是一种有效的免疫反应调节剂。 | ||
| E3527 | Glossy privet fruit Extract | Glossy Privet Fruit Extract是从女贞Ligustrum lucidum的果实中提取的，具有免疫调节作用。 | ||
| S3997 | Oxaceprol | Oxaceprol (N-acetyl-L-hydroxyproline) 是一种抗炎性药物，用于治疗骨关节炎。 | ||
| E3818 | Solidago Decurrens Extract | Solidago Decurrens Extract 提取自一枝黄花Solidago decurrens，可药用促进止血和治疗各种疾病，包括蛇咬伤、痈肿和疔疮。 | ||
| S6249 | Picolinic acid (PCL 016) | Picolinic acid (PCL 016)是色氨酸的吡啶羧酸盐代谢物，一种抗感染试剂和免疫调节剂。 | ||
| E3530 | Boat-fruited sterculia seed Extract | Boat-Fruited Sterculia Seed Extract是从胖大海boat-fruited sterculia中提取的，对急性炎症有抑制作用。 | ||
| E3821 | Alpinia Oxyphyllae Extract | Alpinia Oxyphyllae Extract 提取自益智仁Alpinia oxyphyllae，在调节与β-淀粉样蛋白沉积、tau 蛋白磷酸化、慢性炎症、氧化应激相关的多种信号通路方面具有有效的活性。 | ||
| A2036 | Magrolimab (anti-CD47) | Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) 是一流的巨噬细胞免疫检查点抑制剂，主要与 CD47 的 N 末端焦谷氨酸结合。 |
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| E3824 | Scepteridium Ternatum Extract | Scepteridium Ternatum Extract 提取自阴地蕨Scepteridium ternatum，用于治疗哮喘。 | ||
| S5322 | Sodium gualenate | Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound, which is gradually decomposed in the solid state at room temperature. It has anti-inflammatory and wound-healing effects. | ||
| S9203 | Notopterol | Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities. | ||
| A5212 | CD79a Rabbit Recombinant mAb | |||
| S9204 | Oroxylin A | Oroxylin A (6-Methoxybaicalein) is a flavonoid isolated from Scutellaria root that exhibits multiple pharmacological activities, including anti-oxidative, anti-inflammatory, anti-viral and anti-tumor properties. | ||
| E3139 | Angelica Sinensis Extract | Angelica Sinensis Extract提取自当归Angelica Sinensis (Radix Angelica Sinensis)的干燥根部，其对脑梗死的作用是通过多种途径实现的，包括抗关节硬化、改善微循环、抗血小板聚集、抗炎、抗氧化等作用。 | ||
| S0920 | Ginkgolide J | Ginkgolide J 是银杏叶提取物萜烯三内酯混合物的次要成分，可抑制 GlyR 控制的通道，IC50 为 2.0 μM。Ginkgolide J 还抑制由 Aβ1-42 引起的啮齿动物海马神经元的细胞死亡。银杏内酯 J 具有抗炎活性。 | ||
| E3829 | Epimedium Brevicornu Extract | Epimedium Brevicornu Extract 提取自淫羊藿Epimedium brevicornu Maxim，具有抗炎作用。 | ||
| E3540 | Grapefruit Extract | Grapefruit Extract是从葡萄柚Citrus paradisi Macf.中提取的，可在肠道内作为免疫调节剂，维持肠道巨噬细胞稳态。 | ||
| E3834 | Jasminum Nudiflorum Extract | Jasminum Nudiflorum Extract 从迎春花Jasminum nudiflorum中提取，有助于治疗皮肤病、鼻炎、鼻出血、感染和伤口。 | ||
| A5220 | CD166 Rabbit Recombinant mAb | |||
| E3839 | Houttuynia Cordata Extract | Houttuynia Cordata Extract从鱼腥草Houttuynia cordata中提取，通过抗炎作用改善膀胱损伤并改善膀胱症状。 | ||
| S9216 | Esculentoside A | Esculentoside A, isolated from the Chinese herb phytolacca esculenta, possesses a broad inhibitory effect on a panel of pro-inflammation molecules with less toxicity. | ||
| E3840 | Ulmus Pumila Bark Extract | Ulmus Pumila Bark Extract提取自榆树皮Ulmus pumila L.，可预防由过量产生一氧化氮介导的炎症性疾病。 | ||
| S3956 | Tetramethylpyrazine | Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities. | ||
| S4529 | Idramantone | Idramantone (Kemantane, 5-Hydroxy-2-adamantanone)是一种免疫激动剂。 | ||
| E3069 | Spinach Extract | Spinach Extract从菠菜Spinacia oleracea中提取，对肠道菌群和SCFAs有有益作用。 | ||
| E3554 | Rhizoma homalomenae Extract | Rhizoma Homalomenae Extract是从千年健Rhizoma Homalomenae中提取的，具有抗炎活性。 | ||
| S9222 | Dipotassium glycyrrhizinate | Dipotassium glycyrrhizinate (Neubormitin) 是从甘草根中分离出来的一种广泛使用的抗炎药。 | ||
| E3555 | Acmella oleracea Extract | Acmella Oleracea Extract从千日菊Acmella Oleracea中提取，可降低糜酶活性，抑制氧化应激和炎症。 | ||
| E3846 | Semen Pruni Extract | Semen Pruni Extract提取自郁李仁Semen pruni，用于水肿、皮肤癣菌病、高血压、便秘、慢性气管炎等病症。 | ||
| E3557 | Radix Peucedani Extract | Radix Peucedani Extract是从前胡Peucedani radix中提取的，具有很强的抗炎作用，几个世纪以来一直是治疗呼吸道症状和疾病的重要药物。 | ||
| S9033 | Incensole acetate | Incensole acetate, isolated from Boswellia Resin, is a novel anti-inflammatory compound that inhibits NF-κB activation. | ||
| E3074 | Xanthium Sibiricum Extract | Xanthium Sibiricum Extract从 Xanthium Sibiricum中提取，具有抗炎活性。 | ||
| E3559 | Radix rubiae Extract | Radix Rubiae Extract是从茜草Rubia cordifolia中提取的，具有抗肿瘤、抗氧化、抗血小板聚集、抗炎等作用。 | ||
| S9228 | Schisandrin C | Schisandrin C, a dibenzocyclooctadiene lignan isolated from the fruits of Schisandra chinensis (Turcz.) Baill, has many characteristics including anti-inflammation, anti-tumor, and anti-oxidation. | ||
| S9071 | Nootkatone | Nootkatone, a natural ingredient that occurs in grapefruit and certain other plants, has antioxidant and anti-inflammatory effects. | ||
| E3852 | Oenothera Biennis Extract | Oenothera Biennis Extract提取自月见草Oenothera biennis L.，具有很高的抗炎特性。 | ||
| E3853 | Blueberry Fruit Extract | Blueberry Fruit Extract从越橘Vaccinium的果实中提取，有助于维持血糖水平，减少氧化应激，抗炎作用，预防心血管疾病，抗菌和抗肿瘤活性。 | ||
| E3854 | Coriolus Versicolor Extract | Coriolus Versicolor Extract从云芝Coriolus versicolor中提取，对癌细胞和内皮细胞具有细胞毒活性，并具有抑制与炎症相关的促肿瘤因子表达的能力。 | ||
| E3564 | Celery Extract | Celery Extract提取自芹菜Apium graveolens，对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。 | ||
| S3969 | Veratric acid | Veratric acid (3,4-Dimethoxybenzoic acid)是一种来自植物和水果的简单苯甲酸，具有抗氧化，抗发炎和降血压的作用。Veratric acid 可降低UVB照射后上调的 COX-2 的表达以及 PGE2、IL-6 的水平。 | ||
| E3565 | Celery seed Extract | Celery Seed Extract是从芹菜Apium graveolens的种子中提取的，对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。 | ||
| S0947 | Cafestol | Cafestol是从咖啡豆中提取的天然二萜。Cafestol 诱导细胞凋亡并调节多种炎症介质以减轻炎症。Cafestol 抑制 PI3K/Akt 通路。Cafestol 还可以减少白血病细胞系 HL60 中 ROS 的产生。 | ||
| E3080 | Platycladi Cacumen Extract | Platycladi Cacumen Extract提取自侧柏叶Platycladi Cacumen，传统上用于抗脱发和促进头发生长。 | ||
| S9225 | Santalol | Santalol is a naturally occuring sesquiterpene that has antibacterial, anti-hyperglycaemic, anti inflammatory and antioxidant effects. | ||
| E3567 | Ash bark Extract | Ash Bark Extract是从白蜡树Fraxinus chinensis的树皮中提取的，具有抗炎作用。 | ||
| E3082 | Bupleurum Extract | Bupleurum Extract从柴胡Bupleurum中提取，用于炎症治疗。 | ||
| S9237 | Berberrubine | Berberrubine (Beroline, 9-Berberoline), an isoquinoline alkaloid isolated from many medicinal plants, possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. | ||
| E3860 | Euphorbia Helioscopia Extract | Euphorbia Helioscopia Extract提取自泽漆Euphorbia helioscopia L.，已被用于治疗各种疾病，包括水肿、痰咳、疟疾、痢疾、结痂、结核性瘘管、骨髓炎和癌症。 | ||
| E3570 | Artemisia annua Extract | Artemisia Annua Extract是从黄花蒿Artemisia Annua中提取的，具有抗疟、抗癌作用。 | ||
| A5236 | IRF1 Rabbit Recombinant mAb | |||
| S9240 | Isofraxidin | Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent. | ||
| E2634 | H-Leu-Leu-OMe Hydrochloride | H-Leu-Leu-OMe Hydrochloride (H-LEU-LEU-OME HCL, L-Leucyl-L-Leucine methyl ester)是人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，可选择性消除具有细胞毒性潜能的淋巴细胞，也可以诱导溶酶体途径应激。 | ||
| S9242 | Narirutin | Narirutin (Naringenin-7-O-rutinoside, Isonaringin), a flavanone abundant in citrus fruits, possesses anti-inflammatory and anti-oxidative effects. | ||
| E0365 | Fucoidan | Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖，具有广泛的生物活性，包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。 | ||
| E3188 | Cissus Quadrangularis Extract | Cissus Quadrangularis Extract is extracted from Cissus quadrangularis, which is used in the treatment of osteoporosis, asthma, haemorrhoids, and menstrual disorders. | ||
| E3864 | Cockroach Extract | Cockroach Extract从蟑螂中提取，用于过敏诊断和蟑螂特异性免疫治疗。 | ||
| S9243 | Protosappanin B | Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties. | ||
| E3867 | Fritillariae Thunbergii Bulbus Extract | Fritillariae Thunbergii Bulbus Extract提取自浙贝母Fritillariae thunbergii球茎，用于治疗病理性感冒和湿痰引起的咳嗽和胸闷气道症状。 | ||
| S9245 | Phellodendrine chloride | Phellodendrine chloride, isolated from the Phellodrndron amurensis, exhibits immunosuppressive and anti-inflammatory activities. | ||
| S9246 | Tiliroside | Tiliroside, a glycosidic flavonoid, possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities. | ||
| E0174 | Betamethasone sodium phosphate | Betamethasone sodium phosphate (Betamethasone 21-Phosphate Disodium Salt) 是一种具有抗炎活性的强效糖皮质激素。 | ||
| E3870 | Gardenia Fruit Extract | Gardenia fruit Extract是从茜草科的开花植物栀子（Gardenia jasminoides Ellis.）果实中提取的。栀子不仅用作食用色素，还用作治疗肝病、头痛、黄疸、炎症和高血压的药物。 | ||
| S9248 | Homoorientin | Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent. | ||
| S9005 | Stearyl Glycyrrhetinate | Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry. | ||
| E3875 | Unripe Bitter Orange Extract | Unripe Bitter Orange Extract是从枳citrus unshiu的苦果中提取的，是一种有效的抗过敏功能食品。 | ||
| E3099 | Fritillaria Cirrhosa Seed Extract | Fritillaria Cirrhosa Seed Extract是从川贝母Fritillaria Cirrhosa的种子中提取的，其具有镇咳、祛痰、抗哮喘和抗炎等特性，被广泛用于治疗呼吸道疾病。 | ||
| S9254 | Skimmin | Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. | ||
| E3878 | Stalactitum Extract | Stalactitum Extract从钟乳石Stalactitum中提取，可用作抗哮喘药。 | ||
| E3879 | Glabrous Sarcandra Herb Extract | Glabrous Sarcandra Herb Extract从肿节风Sarcandra glabra (Thunb.)中提取，已被用于治疗喉咙痛、脓肿甚至肿瘤。 | ||
| S8091New | 25-Hydroxycholesterol | 25-Hydroxycholesterol 是一种侧链氧甾醇，是 B 细胞产生 IgA 的选择性抑制剂，EC50≈65 nM。 它影响免疫系统，并在动脉粥样硬化的发病机制中发挥关键作用。 | ||
| S6058 | β-Caryophyllene | β-Caryophyllene是一种天然存在的双环倍半萜烯，是很多精油的组分之一。它是非类固醇的抗炎药物、香料和代谢物。 | ||
| E3883 | Umbellate Pore Fungus Extract | Umbellate Pore Fungus Extract从伞形毛孔菌中提取，具有化湿利尿的作用。 | ||
| S5138 | Citral | Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil. | ||
| S9266 | Ginsenoside Rc | Ginsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects. | ||
| E3107 | Andrographis Herba Extract | Andrographis Herba Extract提取自穿心莲Andrographis paniculata (Burm. F.) Nees的地上部分，具有多种活性，包括抗菌和抗氧化，抗疟疾，抗血管生成，抗炎，抗糖尿病，和体外α-葡萄糖苷酶和α-淀粉酶抑制活性。 | ||
| E3109 | Cymbidium Extract | Cymbidium Extract是从春兰Cymbidium中提取的，具有镇痛和抗炎活性。 | ||
| E3111 | Tribulus Terrestris Extract | Tribulus Terrestris Extract是从刺蒺藜Tribulus Terrestris中提取的，具有抗炎、镇痛、解痉、抗癌、抗菌、驱虫、杀幼虫和抗龋齿等作用。 | ||
| E3890 | Lithospermum Erythrorhizon Extract | Lithospermum Erythrorhizon Extract提取自紫草Lithospermum erythrorhizon，在支气管上皮细胞中具有抗炎反应。 | ||
| S3837 | Echinocystic acid | Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects. | ||
| S9272 | Koumine | Koumine, a Gelsemium alkaloid, possesses analgesic, anti-inflammatory and neurosteroid modulating activities. | ||
| E3243 | Pinus Pinaster Bark Extract | Pinus Pinaster Bark Extract从海岸松Pinus Pinaster的树皮中提取，具有抗炎作用。 | ||
| E3892 | Viola Philphica Munda Extract | Viola Philphica Munda Extract从紫花地丁Viola philphica munda中提取，含有多糖和止痛剂（具有镇痛作用），是一种利尿剂。 | ||
| S6136 | (±)-α-Bisabolol | α-bisabolol是一种植物来源的油性倍半萜烯醇，具有抗炎和抗菌活性。 | ||
| E3894 | Ardisia Japonica Extract | Ardisia Japonica Extract从紫金牛Ardisia japonica中提取，用于治疗咳嗽和止血。 | ||
| S3841 | Eleutheroside B | Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties. | ||
| E0022 | Ophiopogonin D | Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) 是一种从中草药麦冬中分离得到的甾体糖苷，具有抗肿瘤作用。Ophiopogonin D 可通过调节 ITGB1/FAK/Src/AKT/β-catenin/MMP-9 信号轴抑制TGF-β1介导的MDA-MB-231细胞转移行为。Ophiopogonin D 还通过抑制小鼠肺上皮细胞中的 AMPK/NF-κB 通路来减轻 PM2.5 诱导的炎症。 | ||
| E0020 | Lupenone | Lupenone (Lup-20(29)-en-3-one, lupeone) 是一种分离的化合物，具有抗氧化、抗炎和抗糖尿病活性。 Lupenone 可以通过 PI3K/Akt 通路保护 SH-SY5y 细胞免受 METH 诱导的神经元凋亡。 | ||
| E3247 | Hainan Nightshade Fruit Extract | Hainan Nightshade Fruit Extract是从海南茄Hainan Nightshade的果实中提取的，具有增强免疫力和消除疼痛的作用，因为它可以减少体内的炎症和肿胀。 | ||
| S3501 | Perflubron | Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) 具有抗炎活性，因此会降低人肺泡巨噬细胞中的细胞因子 cytokine 产生。Perflubron 还减弱了对生物和非生物系统的氧化损伤，并且不依赖其抗炎特性。 | ||
| E3603 | Ramulus Mori Extract | Ramulus Mori Extract 来源于桑枝，即植物桑 Morus alba L.的干枝。桑枝是广泛用于治疗糖尿病的传统药物。桑枝的主要活性成分是桑椹苷A、氧化白藜芦醇、白藜芦醇、4-羟基肉桂酸、7-羟基香豆素和桑色素，这些成分已被证明具有抗癌、抗高血压、抗糖尿病和抗炎特性。 | ||
| S3500 | Pentosan Polysulfate Sodium | Pentosan Polysulfate Sodium (PPS, Elmiron) 是一种口服生物可利用的半合成药物，具有抗炎和促软骨形成的特性。Pentosan Polysulfate Sodium 也具有抗 HIV-1 的活性。 | ||
| E3898 | Radix Asteris Extract | Radix Asteris Extract提取自紫苑Aster tataricus L. f.的根和根茎，已用于治疗咳嗽和哮喘。 | ||
| E3899 | Echinacea Extract (flower) | Echinacea Extract (Flower)来源于紫锥花，即紫锥菊（ Echinacea purpurea, Echinacea angustifolia 或 Echinacea pallida）的花朵。紫锥花用于治疗呼吸道感染和炎症，包括普通感冒、咳嗽、支气管炎和口咽炎症。 | ||
| S9280 | Demethoxycurcumin | Demethoxycurcumin, a natural demethoxy derivative of curcumin, has anti-oxidant, anti-inflammatory, anti-cancer, and anti-angiogenesis properties. | ||
| S9281 | Peimine | Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level. | ||
| E3254 | Terminalia Chebula Extract | Terminalia Chebula Extract是从诃子Terminalia Chebula中提取的，具有抗氧化、保护肝脏、保护神经、细胞毒、抗糖尿病和抗炎活性 | ||
| E3609 | Elaeagnus angustifolia Extract | Elaeagnus angustifolia Extract来源于沙枣Elaeagnus angustifolia L.的果实。沙枣果实提取物具有急性和慢性抗炎活性。 | ||
| E3610 | Amomum villosum Extract | Amomum Villosum Extract来源于姜科草本植物砂仁Amomum villosum Lour.。砂仁已被证实可有效治疗肠胃疾病。砂仁水提取物显著减轻炎症性肠病大鼠的肠道炎症。 | ||
| E3257 | Polygoni Multiflori Root Extract | Polygoni Multiflori Root Extract提取自何首乌Polygoni Multiflori的根部，用于治疗已扩散至淋巴结的肺结核、癌症、前列腺炎症（前列腺炎）和便秘。 | ||
| E0025 | 2-Hydroxybenzylamine | 2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) 是一种天然存在于荞麦中的化合物，是二羰基亲电试剂的选择性清除剂，可保护蛋白质和脂质不被这些亲电试剂修饰。2-HOBA 可减少炎症和斑块凋亡细胞，并促进胞吐作用和稳定斑块的特征。2-HOBA 具有用作营养补充剂的潜力，因为它能够防止氧化的破坏作用。 | ||
| A5158 | CD33 Rabbit Recombinant mAb | |||
| S9287 | Genkwanin | Genkwanin (Apigenin 7-methyl ether) is one of the major non-glycosylated flavonoids in herbs. It has a variety of pharmacological effects including anti-inflammatory, anti-bacterial, antiplasmodial, radical scavenging, chemopreventive and inhibiting 17β-Hydroxysteroid dehydrogenase type 1 activities. | ||
| E3613 | Sophora tonkinensis Extract | Sophora Tonkinensis Extract 来源于豆科植物越南槐Sophora tonkinensis Gapnep.的干燥根茎。山豆根用于治疗咽喉疾病。山豆根具有保肝、免疫调节和抗癌作用，对肝脏、神经和心血管系统有明显毒性。 | ||
| S9288 | Casticin | Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation. | ||
| S5973 | Methylprednisolone Acetate | Methylprednisolone (NSC-19987, Medrol) acetate 是一种合成的 glucocorticoid receptor 的激动剂，用于迅速抑制炎症。Methylprednisolone 可以激活 ACE2 并降低 IL-6 的水平，从而改善严重或严重的COVID-19。Methylprednisolone 可显著地降低自噬和细胞凋亡。 | ||
| E3614 | Arnica montana Extract | Arnica Montana Extract是从菊科植物山金车Arnica montana L.的花中提取的。山金车具有抗炎、免疫调节、抗硬化、镇痛、抗真菌、抗氧化、抗菌和抗癌的生物活性。 | ||
| E3261 | Juglandis Semen Extract | Juglandis Semen Extract是从常用于膝关节骨性关节炎治疗的核桃仁Juglandis Semen中提取的。 | ||
| E3309 | Polygala Fallax Hemsl. Rhizome Extract | Polygala Fallax Hemsl. Rhizome Extract提取自Polygala Fallax Hemsl.的根部，其对免疫功能产生影响，具有抗应激、抗炎、活血、调脂、对乙肝病毒体外抑制等作用。 | ||
| E3206 | Spirodelae Herba Extract | Spirodelae Herba Extract是从螺旋藻Spirodelae中提取的，可能是治疗特应性皮炎的有效治疗剂。 | ||
| A5160 | CD23 Rabbit Recombinant mAb | |||
| E3727 | Daphne genkwa Sieb.et Zucc. Extract | Daphne Genkwa Sieb.Et Zucc. Extract源自 Daphne genkwa Sieb. et Zucc.的干燥花朵，是具有泻药、利尿和消炎作用用于流产的中草药。 | ||
| S6551 | Adelmidrol | Adelmidrol是十六酰胺乙醇（PEA）的类似物，具有抗炎活性。 | ||
| E3264 | Black Bone Rattan extract | Black Bone Rattan Extract是从黑骨藤Gardneria angustifolia中提取的，具有祛风湿、通经活血的功效。 | ||
| E3619 | Lonicerae Flos Extract | Lonicerae Flos Extract 是从忍冬科植物山银花Lonicera japonica的花蕾中提取的。山银花是一种传统中药，用于治疗炎症和传染病。金银花提取物提高盲肠结扎和穿刺诱导的脓毒症大鼠的存活率。 | ||
| S4165 | Benzydamine HCl | Benzydamine HCl (AF864)是一种外用的非甾体抗炎药（NSAID），具有抗炎，镇痛，解热和局部麻醉剂的活性。 | ||
| E3620 | Corni Fructus Extract | Corni Fructus Extract是从山茱萸Cornus officinalis Sieb. et Zucc.果实中提取的。山茱萸是一种中药，具有抗炎、糖尿病肾病、肿瘤、抗氧化和抗衰老的药理作用。 | ||
| E3316 | Scutellariae rhizome Extract | Scutellariae Rhizome Extract源自黄芩Scutellaria baicalensis的根茎，以黄芩苷为主要成分，长期以来在中国、日本、韩国作为传统药物和功能食品，用于治疗炎症、发热、肝炎、过敏性疾病、高血压等疾病。 | ||
| S9296 | Fraxin | Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis. | ||
| A5289 | L1CAM Rabbit Recombinant mAb | |||
| S9297 | Kirenol | Kirenol is a biologically active substance isolated from Herba Siegesbeckiae. It has been reported to possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities. | ||
| E3624 | Phytolaccae Radix Extract | Phytolaccae Radix Extract是从商陆（Phytolacca acinosa Roxb.或 Phytolacca americana L.）的干燥根中提取的。商陆被广泛用于治疗炎症相关疾病。 | ||
| E3270 | Black Rice Extract | Blackberry Extract是从黑米中提取的。 | ||
| E3735 | Ficus hirta Vahl Extract | Ficus Hirta Vahl Extract从五指毛桃Ficus Hirta Vahl.提取，具有保肝、抗菌、抗炎等生物活性，改善阿尔兹海默小鼠的记忆功能。 | ||
| S9298 | Corylin | Corylin, a main compound isolated from Psoralea corylifolia L. (Fabaceae), has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties. | ||
| E3217 | Penthorum Chinense Pursh Extract | Penthorum Chinense Pursh Extract是从赶黄草Penthorum Chinense Pursh中提取的，用于治疗外伤、水肿和肝脏疾病。 | ||
| E3626 | Snake Gallbladder Extract | Snake Gallbladder Extract 是从蛇胆中提取的。蛇胆具有多种药理作用，如缓解咳嗽和哮喘，以及提高人体免疫力和视力。在亚洲各国，蛇胆被认为可以提高视力和缓解风湿病。 | ||
| S9300 | Methylprotodioscin | Methyl protodioscin, a bioactive natural compound isolated from Dioscorea collettii Makino (Dioscoreaceae), has numerous pharmacological activities, including anti-inflammation, lipid-lowering, and anticancer activities. | ||
| E3627 | Belamcandae Rhizoma Extract | Belamcandae Rhizoma Extract 提取于植物射干Belamcanda chinensis (L.) DC.的干燥根茎。射干主要用于治疗咽喉痛、支气管炎和慢性气管炎。从射干根茎中提取的异黄酮，包括野鸢尾苷元，被认为不仅具有抗氧化和抗炎作用，而且还具有抗肿瘤活性。 | ||
| S5261 | Ufenamate | Ufenamate (Butyl flufenamate, Flufenamic acid butyl ester, Fenazol) is an anthranilic acid derivative with anti-inflammatory activity. | ||
| S6243 | Ethyl pyruvate | Ethyl pyruvate (CTI-01)是丙酮酸一种简单的脂肪族酯，通过发挥消炎、抗氧化和抗凋亡活性而具有神经保护作用。 | ||
| E3629 | Lycopodii Herba Extract | Lycopodii Herba Extractt提取自伸筋草，即干燥的石松科植物石松Lycopodium japonicum Thunb.的全株。石松具有抗炎、抗氧化、抗肿瘤活性；传统上用于预防和治疗各种疾病，如类风湿性关节炎、挫伤、四肢瘫痪、痛经。 | ||
| S4966 | 4-Methylesculetin | 4-methylesculetin是香豆素衍生物，具有强大的抗氧化和抗炎活性。4-Methylesculetin 可抑制 myeloperoxidase (MPO) 活性并降低 IL-6 水平。 | ||
| E0760 | Neotuberostemonine | Neotuberostemonine (NTS) 是对叶百部(Stemona tuberosa)中的主要镇咳生物碱之一，能够通过抑制巨噬细胞的募集和M2极化对BLM诱导的肺纤维化起到显著的保护作用。 | ||
| E3275 | Nigella Sativa Extract (Seed) | Nigella Sativa Extract (Seed) 从黑种草Nigella Sativa 的种子中提取，可能具有抗糖尿病、抗癌、免疫调节剂、镇痛、抗菌、抗炎和抗氧化特性。 | ||
| E3822 | Coix Lacryma-Jobi Seed Extract | Coix lacryma-jobi seed Extract从薏米Coix lacryma-jobi L.中提取。薏米具有抗炎、降血糖、降低血清中脂质成分含量和降胆固醇活性。 | ||
| E3632 | Rehmanniae Radix Extract | Rehmanniae Radix Extract是从生地黄Rehmannia中提取的，中药用于治疗骨骼疾病，是一种有效的抗骨质疏松症。 | ||
| E3327 | Chinese Fevervine Herb Extract | Chinese Fevervine Herb Extract是从鸡屎藤Paederia foetida中提取的，用于治疗炎症、痔疮和腹泻。 | ||
| S9013 | Paulownin | Paulownin, a furofuran lignan from Paulownia tomentosa, has anti-inflammation, analgesia, immunity, hypoglycemia properties. | ||
| E3226 | Devil's Claw Extract | Devil'S Claw Extract是从钩果草Harpagophytum 中提取的，可用于多种健康状况，包括消化不良、发烧、过敏反应和风湿病。 | ||
| S3780 | Secoisolariciresinol diglucoside | Secoisolariciresinol diglucoside (SDG), a plant lignan isolated from flaxseed, has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer. | ||
| E3063 | Pygeum Topengii Bark Extract | Pygeum Topengii Bark Extract从臀果木Pygeum Topengii树皮中提取，有助于前列腺和肾脏健康和一般炎症。 | ||
| S9309 | Micheliolide | Micheliolide, a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders. | ||
| S9019 | Quillaic acid | Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity. | ||
| S9313 | Atractylenolide III | Atractylenolide III, a major component of Atractylodes rhizome, has anti-inflammatory and anti-angiogenesis activities. | ||
| S5969 | Dicloxacillin Sodium hydrate | Dicloxacillin Sodium hydrate (DLX, Dycill, Dynapen, Pathocil) 是一种青霉素类的窄谱β-内酰胺抗生素，可在临床上水平上诱导药物代谢有关的 CYP enzymes 水平。 | ||
| E3283 | Red Bean Extract | Red Bean Extract是从红豆中提取的，具有多种功能特性，如抗糖尿病、抗衰老、抗炎、抗癌和保护肝脏等。 | ||
| E3358 | Rhizoma Fagopyri Dibotryis Extract | Rhizoma Fagopyri Dibotryis Extract是从金荞麦Rhizoma Fagopyri Dibotryis中提取的，用于治疗急性肺损伤。 | ||
| S4832 | Tolmetin | Tolmetin (Tolectin) 是一种非类固醇的抗炎药，属于杂环乙酸衍生物类，具有止痛和退热作用。 | ||
| S9022 | 20S-Ginsenoside Rg3 | 20S-Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It exihits neuromodulatory, cognition enhancing, anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities. | ||
| E3337 | Larva of a Silkworm with Batrytis Extract | Larva Of A Silkworm With Batrytis Extract是从蚕Bombyx的幼虫中提取的，用于治疗过敏性鼻炎。 | ||
| S9023 | 20S-Ginsenoside Rh2 | 20S-Ginsenoside Rh2 is a ginsenoside found in Panax species and inhibits cancer development, progression, and metastasis. | ||
| E3361 | Calendula officinalis flower Extract | Calendula Officinalis Flower Extract是从金盏菊Calendula Officinalis的花中提取的，具有伤口愈合的特性。 | ||
| S9317 | Forsythoside A | Forsythoside A, one of the main active ingredients in Forsythiae fructus, has been shown to possess anti-bacterial and immunomodulatory properties. | ||
| S9318 | (20R)-Ginsenoside Rh1 | (20R)-Ginsenoside Rh1, isolated from the root of Panax Ginseng, exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer. | ||
| E3288 | Red Raspberry Extract | Red Raspberry Extract提取自红树莓Rubus idaeus，其中含有丰富的生物活性成分，具有降低氧化应激的作用。 | ||
| E3289 | Knoxia Valerianoides Extract | Knoxia Valerianoides Extract从红大戟Knoxia Valerianoides中提取，与其他草药联合应用可用于解毒和治疗癌症和炎症性疾病。 | ||
| S4188 | Sasapyrine | Sasapyrine (Salsalate, NSC-49171) 是一种口服的非甾体类抗炎药。 | ||
| E3366 | Fineleaf Schizonepeta Herb Extract | Fineleaf Schizonepeta Herb Extract是从荆芥Schizonepeta的叶子中提取的，它是一种具有解热、消炎、镇痛和止血作用的传统药物。 | ||
| S4835 | Aceclofenac | Aceclofenac (Preservex, Airtal)是一种非类固醇的抗炎药，具有抗炎和止痛作用。 | ||
| S3932 | Astilbin | Astilbin (Isoastilbin, Neoastilbin, Neoisoastilbin, Taxifolin 3-O-rhamnoside), a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. | ||
| S9324 | Alnustone | Alnustone, a naturally occuring compound found in the rhizomes of Curcuma xanthorrhiza, exhibits anti-inflammatory, antihepatotoxic and antiemetic activities. | ||
| E3346 | Oriental Paperbush flower Extract | Oriental Paperbush flower Extract是从结香Edgeworthia chrysantha的花中提取的，可能是治疗骨质疏松等骨质溶解性疾病的潜在药物。 | ||
| E3294 | Piper Nigrum Seed Extract | Piper Nigrum Seed Extract从胡椒Piper nigrum L.中提取，具有抗菌、抗氧化、抗糖尿病、降血脂、抗炎、镇痛、抗惊厥和神经保护作用。 | ||
| E3374 | Exocarpium Citri Rubrum Extract | Exocarpium Citri Rubrum Extract是从橘红Exocarpium Citri Rubrum中提取的，具有护胃除湿化痰的作用。 | ||
| E3759 | Periploca Sepium Extract | Periploca Sepium Extract来自香加皮Periploca sepium，传统上在东方医学中用于治疗类风湿关节炎(RA)。 | ||
| S3893 | Bornyl acetate | Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic. | ||
| E3351 | Abrus mollis Extract | Abrus mollis Extract从鸡骨草Abrus mollis中提取，是一种民间饮料和汤，有净化肝脏毒素、预防肝脏疾病的作用。 | ||
| E3377 | Symphytum officinale Extract | Symphytum officinale Extract从聚合草Symphytum officinale中提取，在民间医学中常用于促进伤口愈合、消炎和治疗骨折。 | ||
| S9054 | Pectolinarin | Pectolinarin 是Cirsium setidens的一种主要化合物，具有抗炎活性。Pectolinarin 可抑制 IL-6 和 IL-8 的分泌以及 PGE2 和 NO 的产生。Pectolinarin 通过 PI3K/Akt 信号通路的失活来诱导凋亡。 | ||
| E0119New | Iptacopan (LNP023) Hydrochloride | Iptacopan (LNP023) Hydrochloride 是一流的、口服给药、有效且高度选择性的 B 因子（factor B）抑制剂，IC50 为 12 nM，Kd 值为 7.9 nM。Iptacopan 表现出优于其他蛋白酶的出色选择性，在 41 种人类蛋白酶组中IC50都 >30 μM。 | ||
| E3298 | Viscum Coloratum Extract | Viscum Coloratum Extract提取自槲寄生Viscum Coloratum，用于治疗炎症性疾病。 | ||
| E3352 | Radix Tinosporae Extract | Radix Tinosporae Extract从金果榄Radix Tinosporae中提取，是一种治疗各种炎症性疾病的中药。 | ||
| E3378 | Selaginella Extract | Selaginella Extract从卷柏Selaginella中提取，具有相当的生物学特性，可用于新兴护理中的疼痛管理。 | ||
| S9053 | Irisflorentin | Irisflorentin derived from the roots of Belamcanda chinensis (L.) DC. is an herb which has been used for the treatment of inflammatory disorders in traditional Chinese medicine. | ||
| E3505 | Hibiscus syriacus flower Extract | Hibiscus syriacus flower Extract是从木槿Hibiscus syriacus的花中提取的，其中含有有助于皮肤再生和保湿的化合物。 | ||
| S4682 | Loxoprofen | Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) 是非类固醇的消炎药，属于丙酸衍生物。 | ||
| E3574 | Cyclocarya paliurus Extract | Cyclocarya Paliurus Extract是从青钱柳Cyclocarya Paliurus中提取的，具有抗纤维化活性。 | ||
| E3503 | Papaya Leaf Extract | Papaya Leaf Extract是从番木瓜Carica papaya的叶子中提取的，具有抗癌、抗炎、抗糖尿病和抗病毒活性。 | ||
| S3765 | Picroside II | Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. | ||
| S9051 | Asperuloside | Asperuloside, an iridoid glycoside found in Herba Paederiae, is a component from traditional Chinese herbal medicine and exerts anti-inflammatory effect. | ||
| S6593 | Methylprednisolone sodium succinate | Methylprednisolone sodium succinate (U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium)是一种皮质类固醇药物，可减少炎症反应。 | ||
| E3382 | Camu Camu fruit Extract | Camu Camu fruit Extract是从桃金娘科卡姆果Myrciaria dubia McVaugh的果实中提取的，有助于预防氧化应激和由高糖水平引起的皮肤炎症。 | ||
| S9037 | Tenacissoside H | Tenacissoside H, a natural compound found in M. tenacissima, exerts anti-inflammatory and anti-tumor effects. | ||
| E2699 | Tris(2-butoxyethyl) phosphate | 口服暴露于相当于每日可耐受的低剂量Tris (2-butoxyethyl) phosphate (TBEP)水平可能通过促进T辅助2细胞反应、ERα的上调以及MLN和BM微环境的失调而加剧过敏性肺部炎症。 | ||
| E3387 | Sophora flavescens Extract | Sophora Flavescens Extract从苦参Sophora flavescens中提取，用于治疗溃疡性结肠炎湿热积证。 | ||
| E3389 | Sophora alopecuroides seed Extract | Sophora Alopecuroides Seed Extract是从苦豆子Sophora alopecuroides的种子中提取的，具有抗炎活性。 | ||
| S5016 | Isoprinosine | Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) 是一种免疫药理试剂，具有抗病毒活性。 | ||
| S9061 | Hydroxy safflor yellow A | Hydroxy safflor yellow A, a monomer extracted from Carthamus tinctorius L., possesses various kinds of bio-activities, including anti-oxidation, anti-inflammatory actions, anti-platelet aggregation, anti-tumor and anti-myocardial injury effects. | ||
| S3774 | Dehydroandrographolide Succinate Potasium Salt | Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. | ||
| S0836 | TMN355 | TMN355 (Compound 3i) 是一种有效的 cyclophilin A (CypA) 的抑制剂，其IC50值为1.52 nM，可减少泡沫细胞的形成和细胞因子的分泌。TMN355 可用于治疗动脉粥样硬化。 | ||
| S3775 | Ligustrazine hydrochloride | Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities. | ||
| S9064 | Trilobatin | Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect. | ||
| S6404 | Salicylamide | Salicylamide (o-hydroxybenzamide)是一种非处方药，具有镇痛和退热的效果。 | ||
| S3776 | Sophoricoside | Sophoricoside (SOPH)是一种分离自槐花（豆科）的异黄酮，具有多种药理作用，如消炎、抗癌、抑制免疫力等效应。 | ||
| E3589 | Evodia Lepta Bark Extract | Evodia Lepta Bark Extract是从三叉苦Melicope pteleifolia的树皮中提取的，具有抗炎活性。 | ||
| E1134 | ABR-238901 | ABR-238901是一种新型的S100A8/A9阻滞剂，可有效抑制S100A8/A9与晚期糖基化终末产物受体（receptor for advanced glycation endproducts，RAGE）和toll样受体4（toll-like receptor 4，TLR4）的相互作用。 | ||
| E3397 | Coltsfoot Extract | Coltsfoot Extract从款冬花Tussilago farfara中提取，用于缓解人类的炎症以及呼吸道和传染病。 | ||
| S9067 | Pseudoprotodioscin | Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. | ||
| S9036 | (20R)Ginsenoside Rh2 | (20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor. | ||
| S9068 | Trillin | Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation. | ||
| S9384 | Sophocarpine Monohydrate | Sophocarpine, a naturally occurring tetracyclic quinolizidine alkaloid derived from Sophora alopecuroides L, has shown promising therapeutic properties, including anti-inflammatory, anti-nociceptive, and antivirus activities. | ||
| E1386New | KP-457 | KP-457 (TNF-α-converting enzyme) 是 ADAM17 的选择性抑制剂，IC50 为 11.1 nM/L（无细胞试验）。 它还可切割各种分子，如 GPIbα、GPV 和 TNF-α。 | ||
| S9072 | Sweroside | Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects. | ||
| S5044 | Isoxepac | Isoxepac是一种非类固醇的芳基乙酸衍生物，具有抗炎症、解热镇痛活性。 | ||
| E3596 | Phellinus linteus Extract | Phellinus Linteus Extract是从桑黄Phellinus Linteus中提取的，具有免疫调节作用。 | ||
| E3404 | Raphanus sativus seed Extract | Raphanus sativus seed Extract从莱菔 Raphanus sativus种子中提取，具有伤口愈合特性。 | ||
| S5046 | Clonixin | Clonixin (Clonixic acid)是一种非类固醇的消炎药物，具有镇痛、解热和抑制血小板作用。 | ||
| S3790 | Methyl gallate | Methyl Gallate (Methylgallate, Gallic acid methyl ester, Gallicin) is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities. | ||
| S5162 | Isovanillic acid | Isovanillic acid (Acide isovanillique, 3-Hydroxyanisic acid, 3-Hydroxy-p-anisic acid), a metabolite of isovanillin, is a selective inhibitor of aldehyde oxidase. | ||
| E3658 | Double coptis chinensis Extract | Double Coptis Chinensis Extract是从双黄连中提取的，具有解热消炎的作用。 | ||
| S9083 | Rhapontin | Rhapontin (Ponticin, Rhaponticin, Rhapontigenin glucoside), a stibene-type glycoside distributed widely in medicinal plants of Rheum genus (Polygonaceae), has anti-inflammatory effect and anti-proliferative activity. | ||
| S9084 | Rhoifolin | Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects. | ||
| S3799 | Gentisic acid | Gentisic acid (2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Hydroquinonecarboxylic acid, DHB), an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties. | ||
| S9085 | Corynoline | Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc. | ||
| S9405 | Sesamoside | Sesamoside, a main chemical ingredient iridoid glycoside from Lamiophlomic rotata, has analgesic and anti-inflammatory effects in animal studies. | ||
| E3696 | Panax notoginseng Extract | Panax notoginseng Extract是由三七Panax notoginseng的干根制成，用于治疗炎症和出血，也抑制酿脓链球菌Streptococcus pyogenes而不影响口腔共生细菌。 | ||
| S9088 | Calycosin-7-O-beta-D-glucoside | Calycosin-7-O-beta-D-glucoside, an isoflavone glycoside isolated from A. mongholicus and A. membranaceus, has antioxidant, anti-inflammatory, and neuroprotective biological activities. | ||
| S9406 | Sauchinone | Sauchinone, one of the active lignan isolated from the roots of Saururus chinensis, possesses diverse pharmacological properties, such as hepatoprotective, anti-inflammatory and anti-tumor effects. | ||
| E3578 | Fringed pink Extract | Fringed Pink Extract是从具有抗炎活性的瞿麦Dianthus superbus中提取的。 | ||
| E3418 | Rhizoma Anemones Raddeanae Extract | Rhizoma Anemones Raddeanae Extract从两头尖Anemone raddeana Regel的根茎中提取，用于治疗风寒症状、手足病痉挛、关节痛、溃疡痛。 | ||
| S9407 | Angoroside C | Angoroside C, an important phenylpropanoid glycoside of the traditional Chinese medicine Scrophulariae Radix, possesses the effects of preventing ventricular remodeling, reducing pulmonary oedema, and reducing blood pressure, as well as having the properties of anti-platelet aggregation, hepatoprotection and anti-nephritis, etc. | ||
| S9090 | Corilagin | Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α. | ||
| S9408 | Beta-Elemonic acid | Beta-Elemonic acid (3-Oxotirucallenoic Acid), a known triterpene isolated from Boswellia (Burseraceae), exhibits anti‑inflammatory effects. | ||
| S9091 | 10-Gingerol | 10-Gingerol is a bioactive compound found in ginger with anti-inflammatory and antioxidant activity. | ||
| E3702 | Eupolyphage sinensis Walker Extract | Eupolyphage sinensis Walker Extract是从土鳖虫 eupolyyphaga sinensis Walker水提物中获取的，该提取物对小鼠的免疫反应有增强作用。 | ||
| S4753 | Ganoderic acid A | Ganoderic acid A (GAA)，是Ganoderma lucidum中具有活性的三萜系化合物，具有镇痛、抗氧化、细胞毒性、保护肝脏和抗肿瘤活性。 | ||
| E3704 | Rumex madaio Makino Extract | Rumex Madaio Makino Extract从蓼科Rumex Madaio Makino中提取，其叶和根组织具有清热解毒、化瘀、排便杀虫等入药作用。 | ||
| S3881 | Scopoletin | Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities. | ||
| S9095 | Senegenin | Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity. | ||
| S5834 | p-Coumaric acid ethyl ester | p-Coumaric acid ethyl ester是p-Coumaric acid的乙酯形式。p-Coumaric acid是一种植物代谢物，具有抗氧化和消炎活性。 | ||
| S9512 | 1,3-Dicaffeoylquinic acid | 1,3-Dicaffeoylquinic acid (Cynarin; Cinarine; 1,5-Dicaffeoylquinic acid) is a phenolic compound found in artichoke. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent. | ||
| E3124 | Cirsii Japonici Herba Extract | Cirsii Japonici Herba Extract提取自大蓟Cirsii Japonici，可用于治疗慢性肾小球肾炎。 | ||
| E3426 | Piper betle L. Extract | Piper Betle L. Extract是从蒌叶Piper betel l.中提取的，这是一种潜在的伤口愈合剂来源。 | ||
| S9417 | Homoplantaginin | Homoplantaginin (Hispidulin-7-glucoside) 是中草药丹参中的主要类黄酮，具有抗炎和抗氧化作用。Homoplantaginin 可抑制 TNF-α 和 IL-6 mRNA 表达，IKKβ和NF-κB 磷酸化。 | ||
| S9098 | Dehydrodiisoeugenol | Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition. | ||
| S9099 | Orientin | Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects. | ||
| S9100 | Fraxinellone | Fraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities. | ||
| S6073 | Diclofenac acid | Diclofenac acid是一种非类固醇的消炎药，具有止痛、消炎和退热活性，在治疗多种急性和慢性疼痛、炎症反应中有效。它能抑制cyclooxygenase-1 (COX-1)和cyclooxygenase-2 (COX-2)，具有相近的效力。 | ||
| E3713 | Vaccariae semen Extract | Vaccariae semen Extract是从王不留行Vaccaria hispanica (Mill.) Rauschert的干燥成熟种子中提取的，用于治疗泌尿系疾病，如良性前列腺增生(benign prostatic hyperplasia, BPH)和泌尿系感染。 | ||
| E3714 | Clematis chinensis Extract | Clematis Chinensis Extract来自毛茛科威灵仙Clematis chinensis Osbeck的干根，广泛用于各种关节炎相关疾病的治疗。 | ||
| E3715 | Crinum Asiaticum Extract | Crinum Asiaticum Extract提取自文殊兰Crinum asiaticum L. var. sinicum (Roxb. ex Herb.) Baker，用于临床治疗抗炎、活血，尤其是紫癜、风湿关节痛、创伤性损伤，现在也用于治疗癌症。 | ||
| S4706 | Eugenol | Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol)是一种自然存在的香味化合物，发现于丁香油和其他植物中。Eugenol通过增加组胺释放和细胞免疫发挥其生理作用。 | ||
| S9106 | Eleutheroside E | Eleutheroside E, a principal component of Eleutherococcus senticosus (ES), has anti-inflammatory effects by inhibiting NF-κB and protecting against myocardial infarction. | ||
| S9425 | Trifolirhizin | Trifolirhizin, a natural pterocarcan flavonoid extracted from Sophora flavescens, has many pharmacological activities, such as hepatoprotective, anti-inflammatory, anti-proliferation, and skin-whitening. | ||
| A2033 | Vibostolimab (anti-TIGIT) | Vibostolimab (anti-TIGIT, MK-7684) 是一种人源化单克隆抗体，与具有免疫球蛋白和 ITIM 结构域 (TIGIT) 的 T 细胞免疫受体结合，阻断 TIGIT 与其配体 CD112 和 CD155 之间的相互作用，从而激活 T 淋巴细胞，帮助破坏肿瘤细胞。 | ||
| E3717 | Lactuca sativa Extract | Lactuca Sativa Extract来自菊科莴苣Lactuca Sativa ，这种植物的种子用于缓解炎症和骨痛。 | ||
| S9427 | Tabersonine | Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus and shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity. | ||
| E3718 | Glaucescent Fissistigma Root Extract | Glaucescent Fissistigma Root Extract提取自番荔枝科乌骨藤Fissistigma glaucescens (Hance) Merr.根部，可能通过提高免疫功能而起到抗肿瘤作用。 | ||
| S5579 | Chelidonic acid | Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) 是在几种植物中发现的次级代谢产物，对实验动物的过敏性疾病具有治疗潜力。Chelidonic acid 通过阻断HMC-1细胞中的 NF-κB 和 caspase-1 来抑制 IL-6 的产生。Chelidonic acid 也是 glutamate decarboxylase 的抑制剂，其Ki值为1.2 μM。 | ||
| E3440 | Tamarindus indica seed Extract | Tamarindus indica seed Extract提取自罗望子Tamarindus indica种子提取物，有助于减轻炎症和炎症引起的软骨退变。 | ||
| S9431 | Dehydrocorydalin | Dehydrocorydalin is an alkaloidal component isolated from Rhizoma corydalis. It has anti-inflammatory and anti-tumor effects and can protect the cardiovascular system. | ||
| E3145 | Kochiae Fructus Extract | Kochiae Fructus Extract从地肤子Kochia scoparia (L.) Schrad.中提取，由于具有抗炎、抗糖尿病、杀虫、抗过敏、止痒、抗类风湿性关节炎等药理活性而受到广泛关注。 | ||
| E3722 | Zaocys dhumnades Extract | Zaocys Dhumnades Extract提取自乌梢蛇 Zaocys dhumnades 的干燥成体，具有驱寒祛风、疏通经络、镇静等功效，主要用于治疗风湿、腿手麻木、截瘫、抽搐痉挛，以及中国等亚洲国家破伤风、麻风病螨病。 | ||
| S9112 | Kaempferitrin | Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities. | ||
| S9113 | Ononin | Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects. | ||
| S9433 | Tubeimoside II | Tubeimoside II (Tubeimoside B), a natural triterpenoid saponin isolated from herb, show anti-inflammatory, antitumor, and antitumor-promoting effects. | ||
| S4709 | Latanoprost | Latanoprost (Xalatan, PhXA41) 是前列腺素F2α的类似物，是前列腺素类选择性FP受体的激动剂。Latanoprost增加葡萄膜巩膜外流，因而减少眼压。 | ||
| E3149 | Pheretima Extract | Pheretima Extract 从地龙Pheretima中提取，对哮喘、咳嗽、发烧等多种炎症性疾病有疗效。 | ||
| E3445 | Hibiscus sabdariffa flower Extract | Hibiscus sabdariffa flower Extract从洛神葵Hibiscus sabdariffa的花中提取，通过增加抗炎细胞因子表达和减少促炎细胞因子表达来增强抗炎作用。 | ||
| E0202 | Benzoylmesaconine | Benzoylmesaconine (Mesaconine 14-benzoate) 是一种主要的乌头生物碱，从几种乌头属植物中分离出来，具有很强的药理活性，如镇痛和抗炎。 | ||
| E3446 | Chinese Starjasmine stem Extract | Chinese Starjasmine Stem Extract是从络石藤Trachelospermum jasminoides的茎中提取的，用于治疗炎症相关疾病。 | ||
| S9116 | Chikusetsusaponin IVa | Chikusetsusaponin IVa (Calenduloside F) 是三萜类皂苷的主要活性成分，具有多种药理活性，包括对各种癌细胞的细胞毒活性，抗炎活性，预防龋齿和诱导人五味子霉素肾毒性。Chikusetsusaponin IVa 也是一种新型的 AMPK 激活剂。 | ||
| E3739 | Panax quinquefolium Extract | Panax Quinquefolium Extract是从西洋参Panax quinquefolium L.中提取的，其活性成分-人参皂苷-已被证明具有广泛的不同的生物活性，导致低血糖、抗炎、心脏保护和抗肿瘤的效果。 | ||
| S9437 | Echinatin | Echinatin is a licorice extract that displays antioxidant properties and anti-inflammatory activities. | ||
| S6439 | Talniflumate | Talniflumate (MSI-1995)是一种抗炎药，在治疗囊胞性纤维症、慢性阻塞性肺病和哮喘中被用作粘蛋白调节剂。Talniflumate 也是一种人钙激活的氯离子通道(chloride channels)抑制剂。 | ||
| S6448 | Ibuprofen piconol | Ibuprofen piconol (U75630) 是一种非甾体抗炎药 (NSAID)，可局部缓解主要的热灼伤和晒伤。 | ||
| E0205 | Strictosamide | Strictosamide 是 Nauclea officinalis Pierre ex Pitard（茜草科）的主要代表性成分，具有抗炎和镇痛活性。 | ||
| S3106 | Pidotimod | Pidotimod(Pidotomod)是一种合成的二肽分子，对适应性和先天性免疫反应都有生物学免疫活性。对动物和人的样本进行体外研究发现Pidotimod对适应性和先天性免疫反应都有很好的活性，这一结论也在体内实验中得到了确认。这些活性已经应用到临床，在减轻儿童上呼吸道和尿道感染复发率上效果良好。在成人呼吸道感染复发的抑制上也有同样效果。 | ||
| S9120 | Scutellarein | Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities. | ||
| S9439 | Kaurenoic acid | Kaurenoic acid (kaurenoate, kaur-16-en-18-oic acid) is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, the mechanisms may through inhibition of iNOS and COX-2 expression. | ||
| S9440 | Naringenin chalcone | Naringenin chalcone (Chalconaringenin, Isosalipurpol, trans-2'4'6'4-tetrahydroxychalcone) is the main active component of tomato skin extract, has been proposed as an antioxidant, an anti-inflammatory, and a regulator of fat and sex hormone metabolism. | ||
| S6472 | Tinoridine hydrochloride | Tinoridine hydrochloride (Y-3642)是一种非类固醇的消炎药物，具有有效的抗氧化活性。 | ||
| E3157 | Erycibes Caulis Extract | Erycibes Caulis Extract 从丁公藤Erycibes Caulis中提取，用于治疗类风湿性关节炎。 | ||
| S3892 | Isopsoralen | Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses. | ||
| S9123 | Eriodictyol | Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties. | ||
| S9125 | Apigetrin | Apigetrin (Cosmetin, Cosmosioside, Thalictiin, Cosmosin, Apigenin 7-glucoside), a flavonoid found in many plant leaves and seeds, has been known to possess antimutagenic, anti-cancer, antioxidant and anti-inflammatory properties. | ||
| E3748 | Epimedium Extract | Epimedium Extract是从淫羊藿Epimedium中提取的，初步证实淫羊藿对骨关节炎有抗骨质疏松和抗炎作用。 | ||
| S9128 | Isoacteoside | Isoacteoside, a phenylethanoid isolated from Monochasma savatieri Franch. ex Maxim., is an anti‐inflammatory herb widely used in traditional Chinese medicine. | ||
| S9129 | 20(S)-Ginsenoside Rh1 | 20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1)是从红参中提取的主要生物活性化合物之一，在世界范围内，红参已越来越多地用于增强认知和身体健康。它具有抗发炎、抗氧化、免疫调节作用和对神经系统有积极作用的有效特性。20(S)-Ginsenoside Rh1 可抑制 PPAR-γ、TNF-α、IL-6 和 IL-1β 的表达。 | ||
| E3164 | Malvae Fructus Extract | Malvae Fructus Extract是从冬葵子（锦葵Malvae Fructus的种子）中提取的，具有通脉利水消肿、干脓、止泻、止渴的作用，用于治疗坐骨和膀胱结石。 | ||
| E3750 | Opuntia dillenii Extract | Opuntia Dillenii Extract是从仙人掌Opuntia Dillenii Haw (Nagphana)中提取的，传统上用于对抗炎症。 | ||
| E3165 | Rabdosiae Rubescentis Herba Extract | Rabdosiae Rubescentis Herba Extract提取自唇形科冬凌草Rabdosia rubescens (Hemsl.) Hara的地上干燥部分，具有抗菌、抗寄生虫、抗炎、抗癌等多种生物活性。 | ||
| E3462 | Coriaria Root Extract | Coriaria Root Extract从马桑coriaria根中提取，用于治疗麻木、风热引起的牙痛、痰潴留综合征、外伤、急性结膜炎等。 | ||
| S4690 | Escin | Escin (Aescin) 是在欧洲七叶树中所发现的皂苷混合物，具有抗炎、血管收缩的、血管保护作用。 | ||
| S9132 | Harpagide | Harpagide, isolated from the secondary roots of Harpagophytum procumbens (Hp), has valuable medicinal properties, such as anti-inflammatory, analgesic and potential antirheumatic effects. | ||
| E3760 | Cymbopogon Citratus Extract | Cymbopogon Citratus Extract来自香茅Cymbopogon Citratus DC (Stapf.)，具有抗菌、抗原虫、抗风湿、抗肿瘤、保护心脏、抗炎和保护胃的特性。 | ||
| S9136 | Neochlorogenic acid | Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia. | ||
| S2307 | Roquinimex | Roquinimex (FCF 89, Linomide, LS 2616) 可抑制 TNF-α 的分泌。Roquinimex是一种新型的免疫调节剂，可增强自然杀伤细胞(NK)活性和T淋巴细胞相关效应功能。Roquinimex是一种有效的、口服活性的肿瘤抗血管生成剂。 | ||
| E3470 | Mango leaf Extract | Mango Leaf Extract是从芒果Mangifera indica的叶子中提取的，可以减轻肌肉疼痛和损伤，加速肌肉性能的恢复。 | ||
| S4789 | 5-Acetylsalicylic acid | 5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) is a nonsteroidal anti-inflammatory drug. | ||
| E3472 | Spicate clerodendranthus Extract | Spicate Clerodendranthus Extract是从猫须草Spicate Clerodendranthus中提取的，对呼吸道炎症和上呼吸道疾病如口干舌燥、口臭、口苦等有疗效。 | ||
| E3473 | Ternate buttercup root Extract | Ternate Buttercup Root Extract是从猫爪草Ternate Buttercup的根中提取的，能增强免疫系统的活性，减少炎症，清除被称为自由基的有害颗粒，并摧毁癌细胞。 | ||
| E3767 | Justicia Gendarussa Extract | Justicia Gendarussa Extract是从小驳骨Justicia Gendarussa 中提取，在儿童哮喘，风湿病和腹绞痛中有效，也可能有潜力成为男性避孕药的基础成分。 | ||
| S9144 | Solasonine | Solasonine, a natural glycoalkaloid compound, has anti-inflammation and anti-tumor properties. | ||
| E3477 | Rose hip Extract | Rose Hip Extract从玫瑰Rosa L.的果实中提取，用于治疗肾结石、肠胃疾病、高血压和呼吸系统疾病，如支气管炎、咳嗽和感冒。 | ||
| S9220 | Stylopine hydrochloride | Stylopine (Tetrahydrocoptisine, Coptisine), a major component of the leaf of Chelidonium majus L., is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity. | ||
| E3482 | Buddleja Officinalis Extract | Buddleja Officinalis Extract从密蒙花Buddleja officinalis的中提取的，据报道在传统的东方草药中对治疗炎症、结膜高血压和头痛有效。 | ||
| S5043 | Benorylate | Benorylate (Benorilate, Benoral, Benortan) 是阿司匹林和扑热息痛经拼合原理制成，具有消炎、止痛和解热活性。 | ||
| S9148 | Peiminine | Peiminine (Verticinone, Zhebeinone, Raddeanine), a biologically active component extracted from Fritillaria walujewii Regel, has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth. | ||
| S9488 | Praeruptorin D | Praeruptorin D是前胡中的成分，具有抗肿瘤和消炎活性。 | ||
| E0208 | Herbacetin | Herbacetin 是一种存在于亚麻籽中的天然类黄酮化合物，具有很强的抗氧化、抗肿瘤和抗炎活性。 | ||
| S9264 | Decursin | Decursin is a pyranocoumarin obtained from the roots of Angelica gigas Nakai that exhibits anti-cancer, anti-inflammatory and neuroprotective activities. | ||
| E3487 | Ecliptae Herba Extract | Ecliptae Herba Extract是从墨旱莲Eclipta中提取的，具有抗骨质疏松作用。 | ||
| A2044 | Omalizumab (anti-IgE) | Omalizumab (anti-IgE)是一种针对人免疫球蛋白 E (IgE)的重组人源化单克隆抗体，KD 为 0.393 nM。Omalizumab (anti-IgE)与人 FcγRIIb 受体结合的 KD 为 6.37 uM。 | ||
| E3001 | Donkey-hide gelatin Extract | Donkey-hide gelatin Extract来源于阿胶，阿胶是药食同源，可以增强免疫反应，改善代谢平衡，治疗妇科疾病。 | ||
| A5170 | Phospho-LAT (Y191) Rabbit Recombinant mAb | |||
| S9920 | GYY4137 | GYY4137 是一种新型水溶性硫化氢 (hydrogen sulfide, H2S) 释放分子，具有血管扩张剂和抗高血压活性。GYY4137 通过阻断 STAT3 通路显示出有效的抗肝细胞癌活性。GYY4137 还显示出抗炎活性。 | ||
| E3492 | Vitex negundo seed Extract | Vitex Negundo Seed Extract是从牧荆Vitex negundo的果实中提取的，用于治疗风湿病和关节炎症。 | ||
| E0193 | Mometasone Furoate Hydrate | Mometasone Furoate (SCH 32088) Hydrate 是一种具有抗炎活性的合成糖皮质激素。 | ||
| S9157 | Neoandrographolide | Neoandrographolide, a principle diterpenoids isolated from A. paniculata, exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities. | ||
| E3494 | Oyster Shell Extract | Oyster Shell Extract是从牡蛎Ostreidae的壳中提取的，具有抗炎作用。 | ||
| E0129 | Oxysophocarpine | Oxysophocarpine (OSC) 是从 Sophora alopecuroides 中提取的生物碱。Oxysophocarpine 通过靶向 Nrf2/ HO-1 轴抑制口腔鳞状细胞癌 (OSCC) 的生长和转移。OSC 通过减弱 MAPK 来保护细胞免受细胞凋亡和炎症反应并削弱 miR-155 活性和 NF-κB 通路。 | ||
| S4524 | 2-Ethoxybenzamide | 2-Ethoxybenzamide (Ethenzamide) 是一种常见的止痛剂和消炎药，用于缓解发热发烧、头痛和其他的轻微疼痛。 | ||
| S5466 | Saikosaponin A | Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inflammatory, immunomodulatory, and anti-bacterial activities. | ||
| E3497 | Momordicae Semen Extract | Momordicae Semen Extract是从木鳖子Momordicae semen中提取的，具有抗胃炎和伤口愈合的作用。 | ||
| S5463 | Curcurbitacin IIA | Curcurbitacin IIA (Cucurbitacin Iia, CuIIa, Hemslecin A, Dihydrocucurbitacin Q1) is the major active component of the Helmseya amabilis root and is known to have antiviral and anti-inflammatory effects. | ||
| S9161 | Ziyuglycoside II | Ziyuglycoside II is an active compound of Sanguisorba officinalis L. that has anti-inflammation, antioxidation, antibiosis, and homeostasis properties. | ||
| E0131 | Luteolin-7-O-glucuronide | Luteolin-7-O-glucuronide (Luteolin 7-glucuronide) 是一种存在于植物中的黄酮糖苷。Luteolin-7-O-glucuronide 具有抗微生物、抗氧化、抗诱变、抗基因毒性、抗炎和抗关节炎活性。 | ||
| E3787 | Flos Inulae Extract | Flos Inulae Extract提取自旋复花Flos Inulae，具有抗突变、抗酪氨酸酶、抗炎等作用。 | ||
| S3906 | Astragalus polyphenols | Astragalus polyphenols(2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside) is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions. | ||
| E0222 | Glaucocalyxin A | Glaucocalyxin A 是一种从 Rabdosia japonica var 中分离出来的具有生物活性的 ent-kauranoid 二萜。Glaucocalyxin A具有抗肿瘤和抗炎活性。Glaucocalyxin A 通过人膀胱癌细胞中的 PI3K/Akt 通路诱导 G2/M 细胞周期停滞和凋亡。 | ||
| S9551 | Uvaol | Uvaol是一种从橄榄渣油的非甘油酯组分发现的五环三萜，具有促炎-抗炎活性。 | ||
| E3789 | Saussurea Involucrata Extract | Saussurea Involucrata Extract来自雪莲Saussurea involucrata Matsum. & Koidz.的花朵，在维吾尔和中医中，长期用于治疗类风湿关节炎、感冒咳嗽、胃痛、痛经、高原反应等。 | ||
| S9165 | Poncirin | Poncirin (Isosakuranetin-7-neohesperidoside), extracted from trifoliate orange, has anti-bacterial and anti-inflammatory activities. | ||
| E0226 | Chebulagic acid | Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的，是一种可逆的、非竞争性的麦芽糖酶（maltase）抑制剂，Ki 值为 6.6 μM。Chebulagic acid 在 LPS 刺激的 RAW 264.7 细胞中显示出有效的抗炎作用。Chebulagic acid 还显示出有效的 COX-LOX双重抑制活性，对 COX-1、COX-2 和 5-LOX 的 IC50 值分别为 15 μM、0.92 μM 和 2.1 μM。 | ||
| E3476 | Myrrh Extract | Myrrh Extract是从没药Commiphora myrrha中提取的，用于治疗炎症性肠病。 | ||
| S9167 | Columbin | Columbin, a diterpenoid furanolactone, is a potential anti-inflammatory drug. | ||
| S9560 | Anisodamine Hydrobromide | Anisodamine (6-Hydroxyhyoscyamine)是天然存在的阿托品（atropine）衍生物，具有消炎活性。它能抑制α1-adrenergic receptors和mAChRs。 | ||
| E0233 | 14-Deoxy-11,12-didehydroandrographolide | 14-Deoxy-11,12-didehydroandrographolide (deAND)，一种在穿心莲 (Burm. f.) Nees 中的二萜类化合物，具有降血压、抗炎、抗哮喘和抗癌活性。 | ||
| E3791 | Surgentodoxa Cuneata Extract | Surgentodoxa Cuneata Extract来自血藤Surgentodoxa Cuneata，具有抗炎、抗氧化、抗肿瘤、抗菌和抗败血症活性。 | ||
| A5093 | NFAT1 Rabbit Recombinant mAb | |||
| S5360 | Diflorasone | Diflorasone acts as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties. | ||
| E3793 | Urtica Fissa Extract | Urtica Fissa Extract是从荨麻科荨麻Urtica Fissa 中提取的，荨麻根是民族医学中治疗风湿病和荨麻疹的常用中药。 | ||
| A5183 | CD14 Rabbit Recombinant mAb | |||
| S9171 | Harpagoside | Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects. | ||
| E3500 | Agaric Extract | Agaric Extract是从木耳agaricales中提取的，具有抗炎和相关药理活性。 | ||
| S9172 | Phellodendrine | Phellodendrine, a quaternary ammonium alkaloid extracted from the dried bark of Phellodendrom chinensis Schneid and Phellodendrom amurense Rupr, has the effect of suppressing cellular immune response, reducing blood pressure and antinephritis. | ||
| S6742 | Etofenamate | Etofenamate是一种非甾体抗炎药，用于治疗关节及肌肉痛。 | ||
| E3501 | Hibiscus mutabilis flower Extract | Hibiscus Mutabilis Flower Extract是从木芙蓉Hibiscus mutabilis的花中提取的，具有预防过敏的作用。 | ||
| S5412 | Loxoprofen Sodium | Loxoprofen sodium is a non-steroidal anti-inflammatory drug. | ||
| S9174 | Xanthotoxol | Xanthotoxol (8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen), a biologically active linear furocoumarin found in a large number of plants, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects. | ||
| S9175 | Macranthoidin A | Macranthoidin A, found in the herbs of Lonicera japonica Thunb., has anti-inflammation activity. | ||
| E0148 | Linalyl Acetate | Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate)是一种天然存在的植物化学物质，存在于许多花卉和香料植物中。Linalyl Acetate是一种潜在的抗炎剂。 | ||
| S9180 | Tussilagone | Tussilagone, isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is used as a traditional oriental medicine for asthma and bronchitis. It shows anti-inflammatory activity in in vitro studies. | ||
| E0780 | MNITMT | MNITMT是一种强效的免疫抑制剂，且无骨髓毒性。 | ||
| S5729 | Fosfosal | Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro. | ||
| S9183 | Ruscogenin | Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities. | ||
| S5451 | Ferulic acid methyl ester | Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer. | ||
| S9184 | Forsythoside B | Forsythoside B 是从中药民间植物轮枝（Lamiophlomis rotata Kudo）的叶子中分离出来的一种苯乙胺类苷。Forsythoside B 具有有效的神经保护作用，并具有抗发炎、抗氧化和防腐特性。Forsythoside B 可以抑制 TNF-alpha、IL-6、IκB 并调节 NF-κB。 | ||
| S3928 | Baccatin Ⅲ | Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It exhibits immunomodulatory and anticancer chemotherapeutic activities. | ||
| E0211 | Dihydroberberine | Dihydroberberine是小檗碱 (BBR) 的氢化衍生物，通过双重调节 NF-κB 和 MAPK 信号通路发挥抗炎作用。 | ||
| A2102 | Anti-mouse CD8α-InVivo | Anti-mouse CD8α(克隆号：2.43)可与小鼠CD8α结合反应。CD8是一种穿膜糖蛋白，是T细胞受体（TCR）的协同受体。有助于后续与抗原呈递细胞的交流通讯。 |
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| A2028 | Tiragolumab (anti-TIGIT) | Tiragolumab (anti-TIGIT) (RG6058, MTIG7192A) 是一种人源化 IgG1/kappa 单克隆抗体，可与 TIGIT 结合以防止其与其配体 PVR (CD155) 相互作用。 | ||
| A2036 | Magrolimab (anti-CD47) | Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) 是一流的巨噬细胞免疫检查点抑制剂，主要与 CD47 的 N 末端焦谷氨酸结合。 |
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| A2033 | Vibostolimab (anti-TIGIT) | Vibostolimab (anti-TIGIT, MK-7684) 是一种人源化单克隆抗体，与具有免疫球蛋白和 ITIM 结构域 (TIGIT) 的 T 细胞免疫受体结合，阻断 TIGIT 与其配体 CD112 和 CD155 之间的相互作用，从而激活 T 淋巴细胞，帮助破坏肿瘤细胞。 | ||
| A2044 | Omalizumab (anti-IgE) | Omalizumab (anti-IgE)是一种针对人免疫球蛋白 E (IgE)的重组人源化单克隆抗体，KD 为 0.393 nM。Omalizumab (anti-IgE)与人 FcγRIIb 受体结合的 KD 为 6.37 uM。 | ||
| S2286 | Cyclosporin A | Cyclosporin A, 一种非极性环寡肽，是一种免疫抑制剂，与亲环素结合，随后抑制calcineurin，无细胞试验中IC50为7 nM，广泛用于预防器官移植反应中的排斥反应,并已用于在灌注的3D近端小管模型上测试其毒性作用。 |
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| S7434 | TAPI-1 | TAPI-1 是一种ADAM17/TACE抑制剂, 其对细胞因子受体有抑制作用。TAPI-1 也是 Matrix Metalloproteinase (MMP) 的抑制剂。 |
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| S3032 | Bindarit | Bindarit是天然化合物，具有特定抗炎活性，因为选择性抑制炎症趋化因子亚家族，包括单核细胞趋化蛋白MCP-1/CCL2, MCP-3/CCL7, 和 MCP-2/CCL8。 |
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| S1576 | Sulfasalazine | Sulfasalazine是一种磺胺剂，是Mesalazine的衍生物，主要用作抗炎剂。Sulfasalazine 是一种有效的、特异性的 nuclear factor kappa B (NF-κB)、TGF-β 和 COX-2 的抑制剂。Sulfasalazine 可诱导铁死亡、凋亡和自噬。 | ||
| S5004 | Pimecrolimus | Pimecrolimus (Elidel,ASM 981,SDZ-ASM 981)是一种抑免蛋白配体, 可以特异地与胞质受体macrophilin-12结合；是钙调蛋白抑制剂。 |
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| S1514 | Cyclosporine | Cyclosporine是一种钙调酶抑制剂，用作免疫抑制剂药物来组织器官移植中的免疫排斥。 | ||
| S1654 | Phenylbutazone | Phenylbutazone (Butazolidine) 是一种非甾体抗炎剂，用于治疗慢性疼痛，包括关节炎的症状。 | ||
| S8660 | GI254023X | GI254023X (GI 4023, SRI028594)是ADAM10的选择性抑制剂，对ADAM10的选择性是对ADAM17的100倍。它对重组型ADAM10和ADAM17的IC50值分别为5.3 nM和541 nM。GI254023X能够抑制MMP9。 | ||
| S1591 | Bestatin (Ubenimex) | Bestatin (Ubenimex)是竞争性氨肽酶B抑制剂，作用于K562细胞，IC50为100 mg/ml。 |
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| S1622 | Prednisone | Prednisone是一种人工合成的皮质类固醇剂，是特别有效的免疫抑制剂的化合物。 | ||
| S8291 | Atractylenolide I | Atractylenolide I 是A. macrocephala根茎的主要类倍半萜烯类化合物。具有广谱的药理活性，如抗炎、促消化、抗氧化作用。 | ||
| S3758 | Sinomenine hydrochloride | Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent. | ||
| S3608 | Demethylzeylasteral (T-96) | Demethylzeylasteral (T-96)是从Tripterygium wilfordii Hook F.中分离出的活性成分，能够抑制UDP-glucuronosyltransferase (UGT)的亚型UGT1A6和UGT2B7，具有免疫抑制活性。 | ||
| S4268 | Flufenamic acid | Flufenamic acid 是一种非甾体抗炎药物，离子通道调节剂。 | ||
| S9032 | Sanguinarine | Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation. | ||
| S6812 | Z-Guggulsterone | Z-Guggulsterone 是阿育吠陀药用植物 Commiphora mukul 的一种成分，在体外和体内抑制血管生成。Z-Guggulsterone 在小胶质细胞中具有抗炎作用。Z-Guggulsterone 通过内在的线粒体依赖性途径诱导胃癌细胞凋亡。 | ||
| S6239 | PMX-53 | PMX-53 是一种有效的CD88 (C5aR)拮抗剂，抑制C5a诱导的中性粒细胞髓过氧化物酶释放和趋化性，IC50值分别为22 nM 和 75 nM。PMX-53也是Mas-related gene 2 (MrgX2)的激动剂。 | ||
| S5661 | Tiaprofenic acid | Tiaprofenic acid (Tiaprofensaeure, Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain. | ||
| S9055 | Salvianolic acid A | Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck. | ||
| E0206 | Ginkgetin | Ginkgetin 是一种来自银杏叶的双黄酮，具有抗癌、抗炎、抗微生物、抗脂肪生成和神经保护作用。 | ||
| S2512 | Tenoxicam | Tenoxicam(Ro-12-0068)是一种有效的自由基清除剂，IC50为56.7 μM。 | ||
| S3622 | Diammonium Glycyrrhizinate | Diammonium glycyrrhizinate (DG)是一种传统的中草药，从甘草中提取纯化而来。它具有抗炎活性，对生物氧化具有抗性、对膜具有保护性。DG通过抑制NF-κB、TNF-α和细胞间黏附分子1来减少炎症损伤。 | ||
| S5361 | Bendazac | Bendazac (bendazolic acid, AF-983) is a non-steroidal anti-inflammatory drug that delays the cataractogenic process. It may act by preventing protein denaturation. | ||
| E0150 | Carrageenan | Carrageenan (kappa-Carrageenan) 是一种从食用红海藻中提取的天然碳水化合物（多糖）。Carrageenan具有抗凝活性、抗血栓形成活性、抗病毒活性、抗肿瘤活性和免疫调节活性。 | ||
| E3530 | Boat-fruited sterculia seed Extract | Boat-Fruited Sterculia Seed Extract是从胖大海boat-fruited sterculia中提取的，对急性炎症有抑制作用。 | ||
| E3824 | Scepteridium Ternatum Extract | Scepteridium Ternatum Extract 提取自阴地蕨Scepteridium ternatum，用于治疗哮喘。 | ||
| S0920 | Ginkgolide J | Ginkgolide J 是银杏叶提取物萜烯三内酯混合物的次要成分，可抑制 GlyR 控制的通道，IC50 为 2.0 μM。Ginkgolide J 还抑制由 Aβ1-42 引起的啮齿动物海马神经元的细胞死亡。银杏内酯 J 具有抗炎活性。 | ||
| E3829 | Epimedium Brevicornu Extract | Epimedium Brevicornu Extract 提取自淫羊藿Epimedium brevicornu Maxim，具有抗炎作用。 | ||
| E3834 | Jasminum Nudiflorum Extract | Jasminum Nudiflorum Extract 从迎春花Jasminum nudiflorum中提取，有助于治疗皮肤病、鼻炎、鼻出血、感染和伤口。 | ||
| E3839 | Houttuynia Cordata Extract | Houttuynia Cordata Extract从鱼腥草Houttuynia cordata中提取，通过抗炎作用改善膀胱损伤并改善膀胱症状。 | ||
| E3840 | Ulmus Pumila Bark Extract | Ulmus Pumila Bark Extract提取自榆树皮Ulmus pumila L.，可预防由过量产生一氧化氮介导的炎症性疾病。 | ||
| E3554 | Rhizoma homalomenae Extract | Rhizoma Homalomenae Extract是从千年健Rhizoma Homalomenae中提取的，具有抗炎活性。 | ||
| E3555 | Acmella oleracea Extract | Acmella Oleracea Extract从千日菊Acmella Oleracea中提取，可降低糜酶活性，抑制氧化应激和炎症。 | ||
| S9033 | Incensole acetate | Incensole acetate, isolated from Boswellia Resin, is a novel anti-inflammatory compound that inhibits NF-κB activation. | ||
| E3074 | Xanthium Sibiricum Extract | Xanthium Sibiricum Extract从 Xanthium Sibiricum中提取，具有抗炎活性。 | ||
| E3559 | Radix rubiae Extract | Radix Rubiae Extract是从茜草Rubia cordifolia中提取的，具有抗肿瘤、抗氧化、抗血小板聚集、抗炎等作用。 | ||
| E3852 | Oenothera Biennis Extract | Oenothera Biennis Extract提取自月见草Oenothera biennis L.，具有很高的抗炎特性。 | ||
| E3853 | Blueberry Fruit Extract | Blueberry Fruit Extract从越橘Vaccinium的果实中提取，有助于维持血糖水平，减少氧化应激，抗炎作用，预防心血管疾病，抗菌和抗肿瘤活性。 | ||
| E3854 | Coriolus Versicolor Extract | Coriolus Versicolor Extract从云芝Coriolus versicolor中提取，对癌细胞和内皮细胞具有细胞毒活性，并具有抑制与炎症相关的促肿瘤因子表达的能力。 | ||
| E3564 | Celery Extract | Celery Extract提取自芹菜Apium graveolens，对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。 | ||
| E3565 | Celery seed Extract | Celery Seed Extract是从芹菜Apium graveolens的种子中提取的，对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。 | ||
| S0947 | Cafestol | Cafestol是从咖啡豆中提取的天然二萜。Cafestol 诱导细胞凋亡并调节多种炎症介质以减轻炎症。Cafestol 抑制 PI3K/Akt 通路。Cafestol 还可以减少白血病细胞系 HL60 中 ROS 的产生。 | ||
| E3567 | Ash bark Extract | Ash Bark Extract是从白蜡树Fraxinus chinensis的树皮中提取的，具有抗炎作用。 | ||
| E3860 | Euphorbia Helioscopia Extract | Euphorbia Helioscopia Extract提取自泽漆Euphorbia helioscopia L.，已被用于治疗各种疾病，包括水肿、痰咳、疟疾、痢疾、结痂、结核性瘘管、骨髓炎和癌症。 | ||
| E3570 | Artemisia annua Extract | Artemisia Annua Extract是从黄花蒿Artemisia Annua中提取的，具有抗疟、抗癌作用。 | ||
| E0365 | Fucoidan | Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖，具有广泛的生物活性，包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。 | ||
| E3188 | Cissus Quadrangularis Extract | Cissus Quadrangularis Extract is extracted from Cissus quadrangularis, which is used in the treatment of osteoporosis, asthma, haemorrhoids, and menstrual disorders. | ||
| E3867 | Fritillariae Thunbergii Bulbus Extract | Fritillariae Thunbergii Bulbus Extract提取自浙贝母Fritillariae thunbergii球茎，用于治疗病理性感冒和湿痰引起的咳嗽和胸闷气道症状。 | ||
| E3875 | Unripe Bitter Orange Extract | Unripe Bitter Orange Extract是从枳citrus unshiu的苦果中提取的，是一种有效的抗过敏功能食品。 | ||
| E3099 | Fritillaria Cirrhosa Seed Extract | Fritillaria Cirrhosa Seed Extract是从川贝母Fritillaria Cirrhosa的种子中提取的，其具有镇咳、祛痰、抗哮喘和抗炎等特性，被广泛用于治疗呼吸道疾病。 | ||
| E3878 | Stalactitum Extract | Stalactitum Extract从钟乳石Stalactitum中提取，可用作抗哮喘药。 | ||
| E3879 | Glabrous Sarcandra Herb Extract | Glabrous Sarcandra Herb Extract从肿节风Sarcandra glabra (Thunb.)中提取，已被用于治疗喉咙痛、脓肿甚至肿瘤。 | ||
| S8091New | 25-Hydroxycholesterol | 25-Hydroxycholesterol 是一种侧链氧甾醇，是 B 细胞产生 IgA 的选择性抑制剂，EC50≈65 nM。 它影响免疫系统，并在动脉粥样硬化的发病机制中发挥关键作用。 | ||
| E3890 | Lithospermum Erythrorhizon Extract | Lithospermum Erythrorhizon Extract提取自紫草Lithospermum erythrorhizon，在支气管上皮细胞中具有抗炎反应。 | ||
| E3892 | Viola Philphica Munda Extract | Viola Philphica Munda Extract从紫花地丁Viola philphica munda中提取，含有多糖和止痛剂（具有镇痛作用），是一种利尿剂。 | ||
| E3894 | Ardisia Japonica Extract | Ardisia Japonica Extract从紫金牛Ardisia japonica中提取，用于治疗咳嗽和止血。 | ||
| E0022 | Ophiopogonin D | Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) 是一种从中草药麦冬中分离得到的甾体糖苷，具有抗肿瘤作用。Ophiopogonin D 可通过调节 ITGB1/FAK/Src/AKT/β-catenin/MMP-9 信号轴抑制TGF-β1介导的MDA-MB-231细胞转移行为。Ophiopogonin D 还通过抑制小鼠肺上皮细胞中的 AMPK/NF-κB 通路来减轻 PM2.5 诱导的炎症。 | ||
| E0020 | Lupenone | Lupenone (Lup-20(29)-en-3-one, lupeone) 是一种分离的化合物，具有抗氧化、抗炎和抗糖尿病活性。 Lupenone 可以通过 PI3K/Akt 通路保护 SH-SY5y 细胞免受 METH 诱导的神经元凋亡。 | ||
| E3247 | Hainan Nightshade Fruit Extract | Hainan Nightshade Fruit Extract是从海南茄Hainan Nightshade的果实中提取的，具有增强免疫力和消除疼痛的作用，因为它可以减少体内的炎症和肿胀。 | ||
| S3501 | Perflubron | Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) 具有抗炎活性，因此会降低人肺泡巨噬细胞中的细胞因子 cytokine 产生。Perflubron 还减弱了对生物和非生物系统的氧化损伤，并且不依赖其抗炎特性。 | ||
| S3500 | Pentosan Polysulfate Sodium | Pentosan Polysulfate Sodium (PPS, Elmiron) 是一种口服生物可利用的半合成药物，具有抗炎和促软骨形成的特性。Pentosan Polysulfate Sodium 也具有抗 HIV-1 的活性。 | ||
| E3898 | Radix Asteris Extract | Radix Asteris Extract提取自紫苑Aster tataricus L. f.的根和根茎，已用于治疗咳嗽和哮喘。 | ||
| E3217 | Penthorum Chinense Pursh Extract | Penthorum Chinense Pursh Extract是从赶黄草Penthorum Chinense Pursh中提取的，用于治疗外伤、水肿和肝脏疾病。 | ||
| E3283 | Red Bean Extract | Red Bean Extract是从红豆中提取的，具有多种功能特性，如抗糖尿病、抗衰老、抗炎、抗癌和保护肝脏等。 | ||
| E3358 | Rhizoma Fagopyri Dibotryis Extract | Rhizoma Fagopyri Dibotryis Extract是从金荞麦Rhizoma Fagopyri Dibotryis中提取的，用于治疗急性肺损伤。 | ||
| E3288 | Red Raspberry Extract | Red Raspberry Extract提取自红树莓Rubus idaeus，其中含有丰富的生物活性成分，具有降低氧化应激的作用。 | ||
| E3289 | Knoxia Valerianoides Extract | Knoxia Valerianoides Extract从红大戟Knoxia Valerianoides中提取，与其他草药联合应用可用于解毒和治疗癌症和炎症性疾病。 | ||
| E3366 | Fineleaf Schizonepeta Herb Extract | Fineleaf Schizonepeta Herb Extract是从荆芥Schizonepeta的叶子中提取的，它是一种具有解热、消炎、镇痛和止血作用的传统药物。 | ||
| E3346 | Oriental Paperbush flower Extract | Oriental Paperbush flower Extract是从结香Edgeworthia chrysantha的花中提取的，可能是治疗骨质疏松等骨质溶解性疾病的潜在药物。 | ||
| E3294 | Piper Nigrum Seed Extract | Piper Nigrum Seed Extract从胡椒Piper nigrum L.中提取，具有抗菌、抗氧化、抗糖尿病、降血脂、抗炎、镇痛、抗惊厥和神经保护作用。 | ||
| E0119New | Iptacopan (LNP023) Hydrochloride | Iptacopan (LNP023) Hydrochloride 是一流的、口服给药、有效且高度选择性的 B 因子（factor B）抑制剂，IC50 为 12 nM，Kd 值为 7.9 nM。Iptacopan 表现出优于其他蛋白酶的出色选择性，在 41 种人类蛋白酶组中IC50都 >30 μM。 | ||
| E3298 | Viscum Coloratum Extract | Viscum Coloratum Extract提取自槲寄生Viscum Coloratum，用于治疗炎症性疾病。 | ||
| E3352 | Radix Tinosporae Extract | Radix Tinosporae Extract从金果榄Radix Tinosporae中提取，是一种治疗各种炎症性疾病的中药。 | ||
| E3574 | Cyclocarya paliurus Extract | Cyclocarya Paliurus Extract是从青钱柳Cyclocarya Paliurus中提取的，具有抗纤维化活性。 | ||
| E3382 | Camu Camu fruit Extract | Camu Camu fruit Extract是从桃金娘科卡姆果Myrciaria dubia McVaugh的果实中提取的，有助于预防氧化应激和由高糖水平引起的皮肤炎症。 | ||
| E3389 | Sophora alopecuroides seed Extract | Sophora Alopecuroides Seed Extract是从苦豆子Sophora alopecuroides的种子中提取的，具有抗炎活性。 | ||
| S0836 | TMN355 | TMN355 (Compound 3i) 是一种有效的 cyclophilin A (CypA) 的抑制剂，其IC50值为1.52 nM，可减少泡沫细胞的形成和细胞因子的分泌。TMN355 可用于治疗动脉粥样硬化。 | ||
| S9064 | Trilobatin | Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect. | ||
| E3589 | Evodia Lepta Bark Extract | Evodia Lepta Bark Extract是从三叉苦Melicope pteleifolia的树皮中提取的，具有抗炎活性。 | ||
| E1134 | ABR-238901 | ABR-238901是一种新型的S100A8/A9阻滞剂，可有效抑制S100A8/A9与晚期糖基化终末产物受体（receptor for advanced glycation endproducts，RAGE）和toll样受体4（toll-like receptor 4，TLR4）的相互作用。 | ||
| E1386New | KP-457 | KP-457 (TNF-α-converting enzyme) 是 ADAM17 的选择性抑制剂，IC50 为 11.1 nM/L（无细胞试验）。 它还可切割各种分子，如 GPIbα、GPV 和 TNF-α。 | ||
| S9072 | Sweroside | Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects. | ||
| E3596 | Phellinus linteus Extract | Phellinus Linteus Extract是从桑黄Phellinus Linteus中提取的，具有免疫调节作用。 | ||
| E3658 | Double coptis chinensis Extract | Double Coptis Chinensis Extract是从双黄连中提取的，具有解热消炎的作用。 | ||
| E3578 | Fringed pink Extract | Fringed Pink Extract是从具有抗炎活性的瞿麦Dianthus superbus中提取的。 | ||
| E3418 | Rhizoma Anemones Raddeanae Extract | Rhizoma Anemones Raddeanae Extract从两头尖Anemone raddeana Regel的根茎中提取，用于治疗风寒症状、手足病痉挛、关节痛、溃疡痛。 | ||
| S9090 | Corilagin | Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α. | ||
| S4753 | Ganoderic acid A | Ganoderic acid A (GAA)，是Ganoderma lucidum中具有活性的三萜系化合物，具有镇痛、抗氧化、细胞毒性、保护肝脏和抗肿瘤活性。 | ||
| E3426 | Piper betle L. Extract | Piper Betle L. Extract是从蒌叶Piper betel l.中提取的，这是一种潜在的伤口愈合剂来源。 | ||
| S9106 | Eleutheroside E | Eleutheroside E, a principal component of Eleutherococcus senticosus (ES), has anti-inflammatory effects by inhibiting NF-κB and protecting against myocardial infarction. | ||
| E3440 | Tamarindus indica seed Extract | Tamarindus indica seed Extract提取自罗望子Tamarindus indica种子提取物，有助于减轻炎症和炎症引起的软骨退变。 | ||
| E3149 | Pheretima Extract | Pheretima Extract 从地龙Pheretima中提取，对哮喘、咳嗽、发烧等多种炎症性疾病有疗效。 | ||
| E3445 | Hibiscus sabdariffa flower Extract | Hibiscus sabdariffa flower Extract从洛神葵Hibiscus sabdariffa的花中提取，通过增加抗炎细胞因子表达和减少促炎细胞因子表达来增强抗炎作用。 | ||
| E3446 | Chinese Starjasmine stem Extract | Chinese Starjasmine Stem Extract是从络石藤Trachelospermum jasminoides的茎中提取的，用于治疗炎症相关疾病。 | ||
| E3157 | Erycibes Caulis Extract | Erycibes Caulis Extract 从丁公藤Erycibes Caulis中提取，用于治疗类风湿性关节炎。 | ||
| S3892 | Isopsoralen | Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses. | ||
| S9148 | Peiminine | Peiminine (Verticinone, Zhebeinone, Raddeanine), a biologically active component extracted from Fritillaria walujewii Regel, has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth. | ||
| E3487 | Ecliptae Herba Extract | Ecliptae Herba Extract是从墨旱莲Eclipta中提取的，具有抗骨质疏松作用。 | ||
| S9920 | GYY4137 | GYY4137 是一种新型水溶性硫化氢 (hydrogen sulfide, H2S) 释放分子，具有血管扩张剂和抗高血压活性。GYY4137 通过阻断 STAT3 通路显示出有效的抗肝细胞癌活性。GYY4137 还显示出抗炎活性。 | ||
| E3492 | Vitex negundo seed Extract | Vitex Negundo Seed Extract是从牧荆Vitex negundo的果实中提取的，用于治疗风湿病和关节炎症。 | ||
| E3494 | Oyster Shell Extract | Oyster Shell Extract是从牡蛎Ostreidae的壳中提取的，具有抗炎作用。 | ||
| E0129 | Oxysophocarpine | Oxysophocarpine (OSC) 是从 Sophora alopecuroides 中提取的生物碱。Oxysophocarpine 通过靶向 Nrf2/ HO-1 轴抑制口腔鳞状细胞癌 (OSCC) 的生长和转移。OSC 通过减弱 MAPK 来保护细胞免受细胞凋亡和炎症反应并削弱 miR-155 活性和 NF-κB 通路。 | ||
| S5466 | Saikosaponin A | Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inflammatory, immunomodulatory, and anti-bacterial activities. | ||
| E0131 | Luteolin-7-O-glucuronide | Luteolin-7-O-glucuronide (Luteolin 7-glucuronide) 是一种存在于植物中的黄酮糖苷。Luteolin-7-O-glucuronide 具有抗微生物、抗氧化、抗诱变、抗基因毒性、抗炎和抗关节炎活性。 | ||
| E0226 | Chebulagic acid | Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的，是一种可逆的、非竞争性的麦芽糖酶（maltase）抑制剂，Ki 值为 6.6 μM。Chebulagic acid 在 LPS 刺激的 RAW 264.7 细胞中显示出有效的抗炎作用。Chebulagic acid 还显示出有效的 COX-LOX双重抑制活性，对 COX-1、COX-2 和 5-LOX 的 IC50 值分别为 15 μM、0.92 μM 和 2.1 μM。 | ||
| E3476 | Myrrh Extract | Myrrh Extract是从没药Commiphora myrrha中提取的，用于治疗炎症性肠病。 | ||
| S5360 | Diflorasone | Diflorasone acts as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties. | ||
| S5412 | Loxoprofen Sodium | Loxoprofen sodium is a non-steroidal anti-inflammatory drug. | ||
| E0148 | Linalyl Acetate | Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate)是一种天然存在的植物化学物质，存在于许多花卉和香料植物中。Linalyl Acetate是一种潜在的抗炎剂。 | ||
| E0780 | MNITMT | MNITMT是一种强效的免疫抑制剂，且无骨髓毒性。 | ||
| A2001 | Ipilimumab (anti-CTLA-4) | Ipilimumab (anti-CTLA-4)是一种免疫调节单克隆抗体，靶向细胞表面抗原CTLA-4；也是一种免疫检查点抑制剂；MW：148 KD。 |
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| A2009 | Rituximab (anti-CD20) | Rituximab (anti-CD20)是嵌合的anti-CD20单克隆抗体，与B细胞上的CD20抗原结合，结合亲和力为5 nM。MW: 143.86 KD。 | ||
| A5212 | CD79a Rabbit Recombinant mAb | |||
| A5220 | CD166 Rabbit Recombinant mAb | |||
| A5236 | IRF1 Rabbit Recombinant mAb | |||
| A5158 | CD33 Rabbit Recombinant mAb | |||
| A5160 | CD23 Rabbit Recombinant mAb | |||
| A5289 | L1CAM Rabbit Recombinant mAb | |||
| A5170 | Phospho-LAT (Y191) Rabbit Recombinant mAb | |||
| A5093 | NFAT1 Rabbit Recombinant mAb | |||
| A5183 | CD14 Rabbit Recombinant mAb | |||
| E3702 | Eupolyphage sinensis Walker Extract | Eupolyphage sinensis Walker Extract是从土鳖虫 eupolyyphaga sinensis Walker水提物中获取的，该提取物对小鼠的免疫反应有增强作用。 | ||
| S1829 | Pranlukast | Pranlukast (ONO-1078,ono-rs-411) 是一种选择性白三烯受体拮抗剂。 | ||
| S4529 | Idramantone | Idramantone (Kemantane, 5-Hydroxy-2-adamantanone)是一种免疫激动剂。 | ||
| S4709 | Latanoprost | Latanoprost (Xalatan, PhXA41) 是前列腺素F2α的类似物，是前列腺素类选择性FP受体的激动剂。Latanoprost增加葡萄膜巩膜外流，因而减少眼压。 | ||
| S1737 | Prednisolone | Prednisolone是一种人工合成的糖皮质激素，具有抗炎和免疫调节特性。 |
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| S3648 | Amlexanox | Amlexanox是一种抗炎抗过敏免疫调节剂，也是蛋白激酶 TBK1 和 IKK-ε 的抑制剂。 | ||
| S8301 | Ossirene (AS101) | Ossirene (AS101)，一种有效的体内体外免疫调节剂，是新型的IL-1beta转化酶的抑制剂。 | ||
| S8760 | Iberdomide (CC220) | Iberdomide (CC-220) 是一种新型口服免疫调节化合物，靶向cereblon（cereblon是CRL4CRBN E3泛素连接酶复合体的一部分），IC50为60 nM。Iberdomide (CC-220) 可诱导凋亡并具有抗肿瘤和免疫刺激的活性。 | ||
| S7892 | Avadomide (CC-122) | Avadomide (CC-122)，一种新型的多效性修饰剂化合物，在弥漫性大B细胞淋巴瘤（DLBCL）中具有抗肿瘤、免疫调节活性。其分子靶标为cereblon (CRBN)，CRBN是E3泛素化连接酶复合体CRL4CRBN的底物受体。 | ||
| S7516 | Y-320 | Y-320 是一种口服有效的 immunomodulator, 它通过 CD4 T 细胞刺激 IL-15 从而抑制IL-17的产生，其IC50为20到60 nM。 | ||
| S1733 | Methylprednisolone | Methylprednisolone是一种人工合成的皮质类固醇，具有抗炎和免疫调节特性。Methylprednisolone 可激活 ACE2 和降低 IL-6 水平，这样来改善严重或危重的 COVID-19。Methylprednisolone 可显著地减少自噬和凋亡。 |
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| S2787 | Laquinimod | Laquinimod (ABR-215062, LAQ)是有效的免疫调节剂。Phase 3。 | ||
| S7515 | VGX-1027 | VGX-1027 (GIT 27) 是一种口服有效的免疫调节剂。 Phase 1。 | ||
| S3668 | Thymopentin | Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells. | ||
| S5083 | Lentinan | Lentinan (A823605, Bromoduline)，分离纯化自香菇子实体水煮提取物，是一种真菌多糖免疫调制剂，具有抗肿瘤活性。 | ||
| S4842 | Balsalazide | Balsalazide (Colazal, Giazo) 是一种氨基水杨酸盐和口服活性的前药，在结肠中被酶解产生具有抗炎效果的mesalazine。Balsalazide 通过调节 IL-6/STAT3 途径来抑制溃疡性结肠炎相关癌变。 | ||
| E3816 | Emilia Sonchifolia Extract | Emilia Sonchifolia Extract 从一点红Emilia sonchifolia中提取，它是一种有效的免疫反应调节剂。 | ||
| E3527 | Glossy privet fruit Extract | Glossy Privet Fruit Extract是从女贞Ligustrum lucidum的果实中提取的，具有免疫调节作用。 | ||
| E3821 | Alpinia Oxyphyllae Extract | Alpinia Oxyphyllae Extract 提取自益智仁Alpinia oxyphyllae，在调节与β-淀粉样蛋白沉积、tau 蛋白磷酸化、慢性炎症、氧化应激相关的多种信号通路方面具有有效的活性。 | ||
| E3540 | Grapefruit Extract | Grapefruit Extract是从葡萄柚Citrus paradisi Macf.中提取的，可在肠道内作为免疫调节剂，维持肠道巨噬细胞稳态。 | ||
| E3082 | Bupleurum Extract | Bupleurum Extract从柴胡Bupleurum中提取，用于炎症治疗。 | ||
| S5973 | Methylprednisolone Acetate | Methylprednisolone (NSC-19987, Medrol) acetate 是一种合成的 glucocorticoid receptor 的激动剂，用于迅速抑制炎症。Methylprednisolone 可以激活 ACE2 并降低 IL-6 的水平，从而改善严重或严重的COVID-19。Methylprednisolone 可显著地降低自噬和细胞凋亡。 | ||
| E3270 | Black Rice Extract | Blackberry Extract是从黑米中提取的。 | ||
| S5969 | Dicloxacillin Sodium hydrate | Dicloxacillin Sodium hydrate (DLX, Dycill, Dynapen, Pathocil) 是一种青霉素类的窄谱β-内酰胺抗生素，可在临床上水平上诱导药物代谢有关的 CYP enzymes 水平。 | ||
| S2307 | Roquinimex | Roquinimex (FCF 89, Linomide, LS 2616) 可抑制 TNF-α 的分泌。Roquinimex是一种新型的免疫调节剂，可增强自然杀伤细胞(NK)活性和T淋巴细胞相关效应功能。Roquinimex是一种有效的、口服活性的肿瘤抗血管生成剂。 | ||
| S8091New | 25-Hydroxycholesterol | 25-Hydroxycholesterol 是一种侧链氧甾醇，是 B 细胞产生 IgA 的选择性抑制剂，EC50≈65 nM。 它影响免疫系统，并在动脉粥样硬化的发病机制中发挥关键作用。 | ||
| E0119New | Iptacopan (LNP023) Hydrochloride | Iptacopan (LNP023) Hydrochloride 是一流的、口服给药、有效且高度选择性的 B 因子（factor B）抑制剂，IC50 为 12 nM，Kd 值为 7.9 nM。Iptacopan 表现出优于其他蛋白酶的出色选择性，在 41 种人类蛋白酶组中IC50都 >30 μM。 | ||
| E1386New | KP-457 | KP-457 (TNF-α-converting enzyme) 是 ADAM17 的选择性抑制剂，IC50 为 11.1 nM/L（无细胞试验）。 它还可切割各种分子，如 GPIbα、GPV 和 TNF-α。 |
Immunology & Inflammation related抑制剂选择性比较
Tags: Immunology & Inflammation related inhibitor|Immunology & Inflammation related agonist|Immunology & Inflammation related activator|Immunology & Inflammation related inducer|Immunology & Inflammation related antagonist|Immunology & Inflammation related signaling pathway|Immunology & Inflammation related assay kit
