STING

抑制剂选择性比较

STING产品

新STING产品
目录号 产品描述 文献引用 实验数据
S6667New

STING inhibitor C-178

C-178是STING的共价抑制剂,与Cys91共价结合。

S6575New

C-176 STING inhibitor

STING inhibitor C-176是一种有效的STING抑制剂。STING是细胞内DNA感应通路的主要信号分子。

S7904New

2',3'-cGAMP

2',3'-cGAMP is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). The binding affinity of 2 ’, 3’-cGAMP to STING is 3.79 nM (Kd value).

S7905New

3',3'-cGAMP

3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

S6652New

H-151

H-151是STING的共价拮抗剂,在人细胞和体内均具有显著的抑制活性。

S8796New

diABZI STING agonist(compound 3)

STING agonist 1 (compound 3)是有效的非核苷类STING激动剂,对于治疗人类癌症具有巨大潜力。

目录号 产品描述 文献引用 实验数据
S6667New

STING inhibitor C-178

C-178是STING的共价抑制剂,与Cys91共价结合。

S6575New

C-176 STING inhibitor

STING inhibitor C-176是一种有效的STING抑制剂。STING是细胞内DNA感应通路的主要信号分子。

目录号 产品描述 文献引用 实验数据
S7904New

2',3'-cGAMP

2',3'-cGAMP is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). The binding affinity of 2 ’, 3’-cGAMP to STING is 3.79 nM (Kd value).

S7905New

3',3'-cGAMP

3',3'-cGAMP activates the endoplasmic reticulum (ER)-resident receptor STING, thereby inducing an antiviral state and the secretion of type I IFNs.

目录号 产品描述 文献引用 实验数据
S6652New

H-151

H-151是STING的共价拮抗剂,在人细胞和体内均具有显著的抑制活性。

目录号 产品描述 文献引用 实验数据
S8796New

diABZI STING agonist(compound 3)

STING agonist 1 (compound 3)是有效的非核苷类STING激动剂,对于治疗人类癌症具有巨大潜力。

Tags: STING antagonist | STING inhibitor | STING agonist