Cyclosporin A (NSC 290193)

For research use only. Not for use in humans.

目录号:S2286 别名: Cyclosporine A, Cyclosporine, Ciclosporin, CsA 中文名称:环孢菌素A

Cyclosporin A (NSC 290193) Chemical Structure

CAS No. 59865-13-3

Cyclosporin A (NSC 290193, Cyclosporine A, Cyclosporine, Ciclosporin, CsA)是一种免疫抑制剂,与亲环素结合,随后抑制calcineurin,无细胞试验中IC50为7 nM,广泛用于预防器官移植反应中的排斥反应。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 1073.15 现货
RMB 786.07 现货
RMB 1957.41 现货
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客户使用Selleck生产的Cyclosporin A (NSC 290193)发表文献44篇:

产品安全说明书

Antineoplastic and Immunosuppressive Antibiotics抑制剂选择性比较

生物活性

产品描述 Cyclosporin A (NSC 290193, Cyclosporine A, Cyclosporine, Ciclosporin, CsA)是一种免疫抑制剂,与亲环素结合,随后抑制calcineurin,无细胞试验中IC50为7 nM,广泛用于预防器官移植反应中的排斥反应。
靶点
calcineurin [1]
(Cell-free assay)
7 nM
体外研究

在T细胞中,Cyclosporin A与亲环蛋白(免疫亲和素)结合[1],形成亲环蛋白-Cyclosporin A复合体,其结合并抑制钙调磷酸酶。[2]Cyclosporin A 抑制钙调磷酸酶,IC50 是7 nM[3],随后阻断NF-AT核转运。 [4]Cyclosporin A通过抑制MTP(线粒体通透性转换孔)的开放而影响线粒体,IC50 是39 nM。[5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
rat H42E cells M4e0VmN6fG:2b4jpZ:Kh[XO|YYm= NVPVXYZZS3m2b4TvfIlkcXS7IHHnZYlve3RicnH0JGg1OkViY3XscJMh[XO|ZYPz[YQh[XNiaX70doFk\WyudXzhdkBCXFBibHX2[YwtKFSFNUC9OFIh|ryP MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTVyMkC1PEc,OTl3MEKwOVg9N2F-
mouse L929 cells MVzDfZRwfG:6aXRCpIF{e2G7 NIPUXo4{KGSjeYO= NU\kfJlsS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVDl{OTDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSVIHHzd4F6NCCLQ{WwQVMxKM7:TR?= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTl6NUG5OUc,OjV7OEWxPVU9N2F-
human Huh-Mono cells MYHDfZRwfG:6aXRCpIF{e2G7 NFvxenc{KGSjeYO= MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIeYguVW:wbzDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F697zOIFPDOVA:OjRizszN M3vaXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NkK1O|Y3Lz5zOE[yOVc3PjxxYU6=
MDCK cells MmnxR5l1d3SxeHnjxsBie3OjeR?= MWrDfZRwfG:6aXPpeJkh[WejaX7zeEBOTEONIHPlcIx{NCCWQ{WwQVkvQSEQvF2= NX7PZ3o{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiyNVIyODBpPkG4NlEzOTByPD;hQi=>
human LCC-6 cells NF21cHVEgXSxdH;4bYPDqGG|c3H5 MX63NkBp NFi0d4NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNS0NvNjDj[YxteyCjZoTldkA4OiCqcoOsJGlEPTB;OD6zJO69VQ>? NV7tPHZ{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKzNlA1ODJpPkKyN|IxPDB{PD;hQi=>
human HeLa cells M3;BUWN6fG:2b4jpZ:Kh[XO|YYm= Mn6wR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{whXEN3ME24MlMh|ryP M1riZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkGyNVAxLz5zOEKxNlExODxxYU6=
african green monkey Vero cells NFr5cGVHfW6ldHnvckBie3OjeR?= NX:xWINTOjRiaB?= NIjGT41CdnSrdnnyZYwh[WO2aY\peJkh[WejaX7zeEBY\XO2IF7pcIUhfmm{dYOgbY5n\WO2ZXSgbY4h[W[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDhd5Nme3OnZDDhd{Bl\WO{ZXHz[UBqdiC4aYLhcEBTVkFic4nueIhme2m|IHHmeIVzKDJ2IHjyd{BjgSCudXPp[oVz[XOnIILldI9zfGW{IHflcoUh[XO|YYmsJGlEPTB;ODFOwG0> MmG4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2NUGyPFYoRjF7NEWxNlg3RC:jPh?=
human Huh-9-13 cells NF[0e3ZEgXSxdH;4bYPDqGG|c3H5 MmH5N{Bl[Xm| NGLmd45EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJfWhvOT2xN{Bk\WyuczDh[pRmeiB|IHThfZMh[nliTWTUJIF{e2G778{MJGNEPTB;NzFOwG0> MnHKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4MkW3OlYoRjF6NkK1O|Y3RC:jPh?=
human HuH6 cells MnLLR5l1d3SxeHnjxsBie3OjeR?= M{fPXFMh\GG7cx?= Mm\UR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTJVJPiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBESzVyPUeg{txO NUXpNVBVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2NlU4PjZpPkG4OlI2PzZ4PD;hQi=>
human Huh5-2 cells NXLLblFWS3m2b4TvfIlkyqCjc4PhfS=> MWmzJIRigXN? NWDlfmhnS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUHWqNT2yJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XliLDDDR|UxRTZizszN MkLoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4MkW3OlYoRjF6NkK1O|Y3RC:jPh?=
human HuH7 cells MWnDfZRwfG:6aXRCpIF{e2G7 MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIeWg4KGOnbHzzJIF{e2W|c3XkJIF{KHKnbHXhd4Uhd2ZibHHjeIF1\SCmZXj5[JJw\2WwYYPlMEBKSzVyPUWuPFEh|ryP NHO1NIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEm0N|M6OCd-MkC5OFM{QTB:L3G+
human 2008 cells NIjEe|hHfW6ldHnvckBie3OjeR?= NVzSUYtEUW6qaXLpeIlwdiCxZjDoeY1idiCPUmCxJIlvKGi3bXHuJFIxODhiY3XscJMtKEmFNUC9OE44QCEQvF2= Ml6yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEe4PFQoRjF6N{C3PFg1RC:jPh?=
human HeLa cells NUP2PJh1TnWwY4Tpc44h[XO|YYm= NH;r[3dCdnSrdnnyZYwh[WO2aY\peJkh[WejaX7zeEBJWFZvMUigbY5n\WO2ZXSgbY4hcHWvYX6gTIVN[SClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJZqemGuIILldIxq[2G2aX;uJIFnfGW{IEeg[IF6e+,:jDDUR|UxRTRwNjFOwG0> MlPVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{MUKxNFAoRjF6MkGyNVAxRC:jPh?=
leukemia CEM cells NEeyRolHfW6ldHnvckBie3OjeR?= NGjwc3hKdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUHWvYX6gUWRTOSCSLVfsfYNweHKxdHXpckBCSkNiVILhcpNxd3K2ZYKgeZNqdmdibHX1b4VucWFiQ1XNJINmdGy|LDDJR|UxRTNwNDFOwG0> NEjQfog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkO2NVM5Pyd-MUKzOlE{QDd:L3G+
human Caco2 cells MUPGeY5kfGmxbjDhd5NigQ>? MkXOcohq[mm2aX;uJI9nKFBvZ4CgbY4hcHWvYX6gR4FkdzJiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJIRq\2:6aX6g[YZndHW6LDDJR|UxRTJwOTFOwG0> NWTvWoRLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzPFI1PThpPkKzN|gzPDV6PD;hQi=>
human MDA435/LCC6MDR cells NGm4N|dEgXSxdH;4bYPDqGG|c3H5 M2HZSlczcA>? M1\mN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSTR|NT;MR2M3VUSUIHPlcIx{KGW6cILld5NqdmdiTVTSJIFnfGW{IEeyJIhze+,:jDDJR|UxRTJwODFOwG0> MmfHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ|MkC0NFIoRjJ{M{KwOFAzRC:jPh?=
guinea pig ventricular myocytes MojNSpVv[3Srb36gZZN{[Xl? MYnJcohq[mm2aX;uJI9nKExvdInw[UBk[WylaYXtJINp[W6wZXygcYVie3W{ZXSgeZNqdmdid3jvcIUu[2WubDDwZZRkcCClbHHtdEBqdiCpdXnu[YEheGmpII\lcpRzcWO3bHHyJI16d2O7dHXzMEBKSzVyPUKg{txO NVLMd3VURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OlExODBpPkKyO|YyODByPD;hQi=>
KB/MDR cell MmW2SpVv[3Srb36gZZN{[Xl? MmfMO|IhcA>? NIjkR5hKdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhU0JxTVTSJINmdGxibHnu[UBi\nSncjC3NkBpeiCxZjDkdpVoKGW6cH;zeZJmNCCLQ{WwQVEvPSEQvF2= M{OzSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NEixPVkyLz5zNUS4NVk6OTxxYU6=
A2780/ADR cells MVPGeY5kfGmxbjDhd5NigQ>? M3faemlvcGmkaYTpc44hd2ZiUD3ncJlkd3C{b4TlbY4h\XiycnXzd4VlKGmwIFGyO|gxN0GGUjDj[YxteyCkeTDjZYxk\WmwIFHNJIF{e2G778{MJGlEPTB;MT60NVI2PCEQvF2= M1nrTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEmwNFk1Lz5zN{i5NFA6PDxxYU6=
human K562/R7 cells MYrGeY5kfGmxbjDhd5NigQ>? MXexJO69VQ>? MlLLO|IhcA>? MoDXVI91\W62aXH0bY9vKG:oIHTvfI9zfWKrY3nuMYlv\HWlZXSgZ5l1d3SxeHnjbZR6KGGpYXnud5Qh\G:6b4L1ZolkcW5vcnXzbZN1[W62IHj1cYFvKEt3NkKvVlch[2WubIOgZZN{\XO|ZXSgZZMh\G:6b4L1ZolkcW5iSVO1NEBifCBzIIXNJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MD63JO69VQ>? MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ|NEC0NUc,OjV4M{SwOFE9N2F-
LLC-PK1 epithelial cells M4ftOWZ2dmO2aX;uJIF{e2G7 MVvJcohq[mm2aX;uJI9nKFBvZ3z5Z49xem:2ZXnuMEBud3W|ZTDMMY1lejGkIHX4dJJme3OnZDDpckBNVENvUFuxJIVxcXSqZXzpZYwh[2WubIOgeZNqdmdiY3HsZ4Vqdi2DTTDwc4xiemm|YYTpc44h[XO|YYpvwKwhUUN3ME2wMlch|ryP NHT5blg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMk[5PVM5QSd-MUK2PVk{QDl:L3G+
mouse L5178 cells M4S4Z2Z2dmO2aX;uJIF{e2G7 NUL2U3Z5OjBibXnudy=> NVPVb|Z4UW6qaXLpeIlwdiCxZjDoeY1idiCDQlPCNU1u\WSrYYTl[EBzcG:mYX3pcoUhOTJ|IHXm[ox2gCCrbjDtc5V{\SCONUG3PEBk\WyuczDlfJBz\XO|aX7nJIh2dWGwIF3EVlEh[W[2ZYKgNlAhdWmwczDifUBHSUOVIHHuZYx6e2m|LDDJR|UxRTBwNkWg{txO MoK1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|NEG3OFUoRjJzM{SxO|Q2RC:jPh?=
KB cell NYi3[oRZTnWwY4Tpc44h[XO|YYm= NHmwPJpKdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhU0JiY3XscEBtcW6nIHHmeIVzKDd{IHigc4Yh\HK3ZzDlfJBwe3W{ZTygTWM2OD1yLk[g{txO NGHZTow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUS4NVk6OSd-MUW0PFE6QTF:L3G+
mouse mammary carcinoma cell line EMT6/AR 1.0 NGK5N4ZHfW6ldHnvckBie3OjeR?= MV\S[ZZmenOjbDDl[oZm[3Rib36geIhmKGGlY4XteYxifGmxbjDv[kBcO0ifLTDkZZVvd3K3YnnjbY4hcW5ibX;1d4UhdWGvbXHyfUBk[XKlaX7vcYEh[2WubDDsbY5mKEWPVE[vRXIhOS5yLDDJR|UxRTBwNESg{txO MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODB7OE[3NUc,OTByOUi2O|E9N2F-
CK1 cells NFjp[HBHfW6ldHnvckBie3OjeR?= MmXrRY51cX[rcnHsJIFkfGm4aYT5JIFo[Wmwc4SgTHBXNTN|IHnu[oVkfGWmIHnuJGNMOSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJZqemGuIILldIxq[2G2aX;uJIFnfGW{IEeg[IF6eyxiVFO1NF0xNjNizszN NHzpOGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEKxNlExOCd-MUiyNVIyODB:L3G+
HEK293 cells NGDpdJBHfW6ldHnvckBie3OjeR?= NH3ndGNKdmirYnn0bY9vKG:oIF;BWHAySjFiKIXub45wf25ib4Lp[4lvMSCneIDy[ZN{\WRiaX6gTGVMOjl|IHPlcIx{KGG|c3Xzd4VlKGG|IIDyc5RmcW5vbXXkbYF1\WRicHn0ZZZie3SjdHnuJJVxfGGtZf-8kEBMcT1yLkKg{txO MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV6N{m4Okc,OjJ3OEe5PFY9N2F-
human MDA435/LCC6MDR cells M{DPTGZ2dmO2aX;uJIF{e2G7 NGfsXVY2KGSjeYO= NGj5O3lOd2S3bHH0bY9vKG:oIGCt[5AhMHWwa37ve44hd3KrZ3nuLUB1emGwc3\lZ5Rm\CCrbjDoeY1idiCPRFG0N|UwVEOFNl3EVkBk\WyuczDhd5Nme3OnZDDhd{Bz\X[ncoPpcocheGGlbHn0ZZhmdCC{ZYPpd5RidmOnIH3lZZN2emWmIHHzJINmdGxic4Xyeol3[WxiYX\0[ZIhPSCmYYnzJIJ6KE2WUzDhd5NigSxiRVO1NF0xNjB|MjFOwG0v MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTl6NUG5OUc,OjV7OEWxPVU9N2F-
human PBMC NEPGUJhRem:uaX\ldoF1cW:wIHHzd4F6 NX:zOZRMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQRm1ENCCLQ{WwQVEzKG6P MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTZ5OUOwPUc,OTV4N{mzNFk9N2F-
mouse T cells Mn\FSpVv[3Srb36gZZN{[Xl? NG[0O5Q1KGSjeYO= M4T2SmludXWwb4P1dJBz\XO|aY\lJIFkfGm4aYT5JIlvKG2xdYPlJHQh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjD0e48hf2G7IH3pfIVlKGy7bYDoc4N6fGVicnXhZ5Rqd25iYX\0[ZIhPCCmYYnzJIJ6KE2WVDDhd5NigSxiaXO1NF0yOSCwTR?= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl6NEm4O{c,OjJ7OES5PFc9N2F-
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MDA-435/LCC6 and MDA-435/LCC6-MDRI NXn2XlBiTnWwY4Tpc44h[XO|YYm= NYO5PYFlS2:wY3XueJJifGmxbjD0bIF1KHKnZIXj[ZMh\GmoZnXy[Y5k\SCrbjDy[ZZmenOjbDDv[kBcO0ifVlLMJIFk[3WvdXzheIlwdiCkZYT3[YVvKE2GQT20N|UwVEOFNjDhcoQhVUSDLUSzOU9NS0N4LV3EVmkh[2WubIOgZpkhPTBnLDDFR|UxKD1iMD62JO69VS5? Mnv0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5OESxOFMoRjFzN{i0NVQ{RC:jPh?=
MDA435/LCC6 MDR1 Mn3LSpVv[3Srb36gZZN{[Xl? M1K1OpJmfmW{c3HsJI9nKF[rbnLsZZN1cW6nIHHjZ5VufWyjdHnvckApXmmwYnzhd5RqdmV8IECuNFA2KHWPKTDpckBOTEF2M{WvUGNEPiCPRGKxJINmdGy|LDDFR|UxKD1iMD62JO69VS5? MnHtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5OESxOFMoRjFzN{i0NVQ{RC:jPh?=
MDA-435/LCC6 (Pgp-negative) NU\BRlR5TnWwY4Tpc44h[XO|YYm= MlrmSYZn\WO2IH;uJJJmfmW{c3HsJI9nKESRWDDhZ4N2dXWuYYTpc44hcW5iTVTBMVQ{PS:OQ1O2JEhR\3BvbnXnZZRqfmVrIHPlcIx{NixiRVO1NEA:KDBwNzFOwG0v MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTd6NEG0N{c,OTF5OESxOFM9N2F-
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MDA-435/LCC6-MDRI MmDoS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MXvHdo94fGhiaX7obYJqfG:{eTDhZ5Rqfmm2eTDvckBOTEFvNEO1M2xESzZvTVTSTUApWGeyLX7l[4F1cX[nKTDoeY1idiCkcnXhd5Qh[2GwY3XyJINmdGy|LjygTWM2OCB;IEGuNUDPxE1w NFnhO|U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUe4OFE1Oyd-MUG3PFQyPDN:L3G+
BTI-TN5B1-4 M1TpRWZ2dmO2aX;uJIF{e2G7 M3vPXGFVWCCqeXTyc4x6e2m|IHnuJI1mdWK{YX7lJIZz[WO2aX;uJIZzd21iSHnnbEBHcX[nIDjCWGkuXE53QkGtOEkh[2WubIOsJGtuKD1iMD6xO{DPxE1w MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTd6NU[4OEc,OTF5OEW2PFQ9N2F-
Jurkat MYDGeY5kfGmxbjDhd5NigQ>? MoXPTY5pcWKrdHnvckBw\iCycn;keYN1cW:wIH;mJGlNNTJic3XjdoV1cW:wIHnuJGp2emujdDDj[YxteyxiSVO1NEA:KDBwMEC3JO69VS5? M2naVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzOEixPVg1Lz5zMUi4NVk5PDxxYU6=
Jurkat MnvZSpVv[3Srb36gZZN{[Xl? M3fVNmlvcGmkaYTpc44hd2ZicILv[JVkfGmxbjDv[kBj\XSjLXfhcIFkfG:|aXThd4UhUUxvMjDSS2EhcW5iSoXyb4F1KGOnbHzzMEBKSzVyIE2gNE4xODhizszNMi=> MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTh6MUm4OEc,OTF6OEG5PFQ9N2F-
LLC-PK1 NXHERnl5TnWwY4Tpc44h[XO|YYm= MV\pcoNz\WG|ZTDpckBXcW6kbHHzeIlv\SCrboTyZYNmdGy3bHHyJIFk[3WvdXzheIlwdiCrbjDNSHIyNWW6cILld5NqdmdiTFzDMXBMOSClZXzsd{whU2liPTCxMlMh|ryPLh?= Ml3HQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF7NkGxNVMoRjFzOU[xNVE{RC:jPh?=
LLC-PK1 NEn1R2RHfW6ldHnvckBie3OjeR?= Mmj1bY5kemWjc3WgbY4hS2GuY3Xpck1CVSCrboTyZYNmdGy3bHHyJIFk[3WvdXzheIlwdiCrbjDNSHIyNWW6cILld5NqdmdiTFzDMXBMOSClZXzsd{whU2liPTC0MlY3KM7:TT6= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTl4MUGxN{c,OTF7NkGxNVM9N2F-
MDCK M1fWfGZ2dmO2aX;uJIF{e2G7 NX\qUZJ7cW6qaXLpeIlwdiCxZjDEbYdwgGmwIITyZY5{\XCrdHjlcIlidCC2cnHud5BwenRiKHLhd4FtKHSxIHHwbYNidCliaX6gUWRTOS2neIDy[ZN{cW6pIF3ER2sh[2WubIOsJGtqKD1iMj6xPEDPxE1w M2HGflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MUO0PVQ2Lz5zMkGzOFk1PTxxYU6=
MDCK MWPGeY5kfGmxbjDhd5NigQ>? NELGT4pqdmirYnn0bY9vKG:oIG\pcoJt[XO2aX7lJJRz[W6|ZYDpeIhmdGmjbDD0doFve3CxcoSgLIJie2GuIITvJIFxcWOjbDmgbY4hVVKSMj3lfJBz\XO|aX7nJG1FS0tiY3XscJMtKEurIE2gPE4yOSEQvF2u M1\BSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MUO0PVQ3Lz5zMkGzOFk1PjxxYU6=
LLC-PK1 M1viSWZ2dmO2aX;uJIF{e2G7 MlLBbY5kemWjc3WgbY4hS2GuY3Xpck1CVSCrboTyZYNmdGy3bHHyJIFk[3WvdXzheIlwdiCrbjDt[JIy[i2neIDy[ZN{cW6pIFzMR{1RUzFiY3XscJMtKEurIE2gN{42KM7:TT6= NXXmNow1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKyN|UzPjdpPkGyNlM2OjZ5PD;hQi=>
LLC-PK1 NGPnSGZHfW6ldHnvckBie3OjeR?= NIDNelZqdmO{ZXHz[UBqdiCFYXzj[YlvNUGPIHnueJJi[2WubIXsZZIh[WOldX31cIF1cW:wIHnuJI1lejGjLXX4dJJme3OrbnegUGxENVCNMTDj[YxteyxiS3mgQUA{NjZ3IN88UU4> MoLvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ{M{WyOlcoRjF{MkO1NlY4RC:jPh?=
HL-60 MnHxSpVv[3Srb36gZZN{[Xl? M4LGXWlvcGmkaYTvdpkh[WO2aY\peJkh[WejaX7zeEBJfW2jbjDmc5JugWyyZYD0bYRmKHKnY3XweI9zKCiIUGKpJI9nKGi3bXHuJIxmfWunbXnhJGhNNTZyIHPlcIx{NCCLQ{KwJF0hOy54IN88UU4> NX7aU3dORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKzOlE{QDhpPkGyN|YyOzh6PD;hQi=>
High Five cells NUXFTYp[TnWwY4Tpc44h[XO|YYm= NWHXRVNrcW6qaXLpeIlwdiCxZjDUZZVzd2OqZX7v[IVwgHmlaH;sZZRmKHWydHHr[UhEe0FiM{D1UUwhOzBiJTDv[kBkd262cn;sLUBqdiCvZX3idoFv\SC4ZYPpZ4xmeyCycnXwZZJm\CCocn;tJGhq\2hiRnn2[UBk\WyuczDpcoZm[3SnZDD3bZRpKHSqZTDBRmNDOTFiYnHjeYxwfmm{dYOsJGtqKD1iOT61JO69VS5? NXPQOI5lRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK0NFQzOzlpPkGyOFA1OjN7PD;hQi=>
MDCKII MojPSpVv[3Srb36gZZN{[Xl? M4HSV4lvcGmkaYTpc44hd2ZiQ3XybZZie3SjdHnuJJVxfGGtZTDpckBQSVSSMj3lfJBz\XO|aX7nJG1FS0uLSTDj[YxteyxiS3mgQUAxNjJ|ODFOwG0v MoXOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ3M{i4NVMoRjF{NUO4PFE{RC:jPh?=
Caco-2 NHTnZZJHfW6ldHnvckBie3OjeR?= M1nPRZRz[W6|ZYDpeIhmdGmjbDD0doFve3CxcoSgc4Yh\Gmpb4jpckAp[mG|YXygeI8h[XCrY3HsLUBqdiCFYXPvMVIh[2WubIOsJGtqKD1iMD6zOUDPxE1w NYLIZZMzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK2N|YyPTNpPkGyOlM3OTV|PD;hQi=>
SK-E2 NU\KWWxXTnWwY4Tpc44h[XO|YYm= M3HKN4lv[3KnYYPlJIlvKGKxZHnwfUBqdnS{YXPlcIx2dGG{IHHjZ5VufWyjdHnvckApSm:maYD5PkAxNjJidV2pJIlvKFONLVWyJINmdGy|IDjlfJBz\XO|aX7nJGJUTVBrLDDJR|UxKD1iNz61JO69VS5? MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjd|OUe1PUc,OTJ5M{m3OVk9N2F-
SK-E2 NVHBT|VnTnWwY4Tpc44h[XO|YYm= NVrLbHJscW6lcnXhd4UhcW5iZHnofYRzd2[udX;y[ZNk\WmwIHnueJJi[2WubIXsZZIh[WOldX31cIF1cW:wIDjkbYh6\HKxZnz1c5Jme2OnaX66JFEhfU1rIHnuJHNMNUV{IHPlcIx{KCineIDy[ZN{cW6pIFLTSXAqNCCLQ{WwJF0hPy56IN88UU4> NVm5blhLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK3N|k4PTlpPkGyO|M6PzV7PD;hQi=>
HEK293 NGrWWWlHfW6ldHnvckBie3OjeR?= Mke1bY5pcWKrdHnvckBw\iCSaHHscI9q\GmwIIXweIFs\SBqUHjhcIxwcWSrbkqgNUB2VSliaX6gU2FVWC2FLXX4dJJme3OrbnegTGVMOjl|IHPlcIx{NCCNaTC9JFAvOiEQvF2u NGDOOIQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEWzNFkxPyd-MUS1N|A6ODd:L3G+
T-cells Moq4SpVv[3Srb36gZZN{[Xl? NV6wbYdZUW6qaXLpeIlwdiCxZjDhcIxw\2WwaXOgZ4VtdHNvc4TpcZVt[XSnZDDwdo9tcW[ncnH0bY9vKGmwIH3veZNmKFRiY3XscJMh[nlibXn4[YQhdHmvcHjvZ5l1\SC{ZXHjeIlwdiCvZYToc4QtKEmFNUCgQUAxNjB|MjFOwG0v NEnC[m89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEW5N|E5Oid-MUS1PVMyQDJ:L3G+
T-cells NUTTSmQ5TnWwY4Tpc44h[XO|YYm= NF7MUlVKdmirYnn0bY9vKG:oIHHscI9o\W6rYzDj[Yxtey2|dHnteYxifGWmIIDyc4xq\mW{YYTpc44hcW5iaIXtZY4hXCClZXzsd{BjgSCvaYjl[EBtgW2yaH;jfZRmKHKnYXP0bY9vKG2ndHjv[EwhUUN3MDC9JFAvODd2IN88UU4> NEfiWWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEW5N|E5Oid-MUS1PVMyQDJ:L3G+
PMBC NHj4RW5HfW6ldHnvckBie3OjeR?= MYG3NkBpenN? MlroSYZn\WO2IH;uJJBzd2yrZnXyZZRqd25ib3[gbJVu[W5icHXybZBp\XKjbDDicI9w\CCvb37vcpVkdGWjcjDj[YxteyBqUF3CR{kh[XRiN{KgbJIhfXOrbnegUXRVKGG|c3H5MEBKSzVyIE2gPE46PyEQvF2u MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTJyM{G2N{c,OTV{MEOxOlM9N2F-
mouse spleen cells M{DDPWN6fG:2b4jpZ4l1gSCjc4PhfS=> NY\v[4hPS3m2b4TvfIlkcXS7IHHnZYlve3RiQlHMRk9kKG2xdYPlJJNxdGWnbjDj[YxteyxiQ1O1NEA:KDFwM{Wg{txONg>? MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzB6MUe2NUc,OTdyOEG3OlE9N2F-
MDCK2 NGHzNXZHfW6ldHnvckBie3OjeR?= NGjUXVZKdmirYnn0bY9vKG:oIHj1cYFvKE2GUkGt[IVx\W6mZX70JIFk[3WvdXzheIlwdiCxZjDjZYxk\WmwLVHNJIV5eHKnc4Pl[EBqdiCPRFPLNkBk\WyuczygTWM2OCB;IEmuN|Qh|ryPLh?= NV\XPIdHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2OlQ{OjdpPkG3OlY1OzJ5PD;hQi=>
HEK293 NXfNeGV6TnWwY4Tpc44h[XO|YYm= NHLxboZKdmirYnn0bY9vKG:oIHPyc5N{NWyrbnvpcochd2ZiaIXtZY4hWGeyIGTNNUBNPjWUL2TNOkBNOzN7Qz;UUVchTjd{ODDteZRidnRiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyCjc4Pld5Nm\CCjczDkdpVoKGyndnXsJINifXOrbnegOVAmKGmwaHnibZRqd25ib3[gZ5Jwe3NibHnub4lv\yCkeTDpcY12dm:kbH;0MEBC[3Srdnn0fUA:KDBwNTFOwG0v MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzh2OEW2N{c,OTd6NEi1OlM9N2F-
HEK293 NH\0cppHfW6ldHnvckBie3OjeR?= MV;Jcohq[mm2aX;uJI9nKGO{b4PzMYxqdmurbnegc4YhcHWvYX6gVIdxKFSPNjDMN|M6Sy:WTUegSlczQENibYX0ZY51KGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMh[XO|ZYPz[YQh[XNiZIL1[{Bt\X[nbDDjZZV{cW6pIEWwKUBqdmirYnn0bY9vKG:oIHPyc5N{KGyrbnvpcoch[nliaX3teY5w[myxdDygRYN1cX[rdImgQUAxNjZizszNMi=> MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzh2OEW2N{c,OTd6NEi1OlM9N2F-
HEK293 M{LqZmZ2dmO2aX;uJIF{e2G7 M3O5SGlvcGmkaYTpc44hd2ZiY4Lvd5MudGmwa3nu[{Bw\iCqdX3hckBR\3BiVF2zWFE6QVJxVF22JGw{OzmFL2TNO{BHPzJ6QzDteZRidnRiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyCjc4Pld5Nm\CCjczDkdpVoKGyndnXsJINifXOrbnegOVAmKGmwaHnibZRqd25ib3[gZ5Jwe3NibHnub4lv\yCkeTDpcY12dm:kbH;0MEBC[3Srdnn0fUA:KDFwMTFOwG0v NEjrdpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{i0PFU3Oyd-MUe4OFg2PjN:L3G+
HEK293 Mk\2SpVv[3Srb36gZZN{[Xl? MV\Jcohq[mm2aX;uJI9nKGO{b4PzMYxqdmurbnegc4YhcHWvYX6gVIdxKFSPNjDGN|Q{Wi:WTU[gUFM{QUNxVF23JGY4OjiFIH31eIFvfCCneIDy[ZN{\WRiaX6gTGVMOjl|IHPlcIx{KGG|c3Xzd4VlKGG|IHTyeYchdGW4ZXygZ4F2e2mwZzC1NEUhcW6qaXLpeIlwdiCxZjDjdo9{eyCuaX7rbY5oKGK7IHntcZVvd2Kub4SsJGFkfGm4aYT5JF0hOTFizszNMi=> MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzh2OEW2N{c,OTd6NEi1OlM9N2F-
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... Click to View More Cell Line Experimental Data

体内研究 Cyclosporin A是一种免疫抑制剂,小鼠,大鼠,和荷兰猪经非肠道给药或者口服给药都有效[6],临床上用于器官移植中预防免疫排斥。[7]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

激酶实验:[3]
- 合并

磷酸酶试验:

纯化的牛脑钙调磷酸酶和钙调蛋白是购买的。含纯化酶的反应混合物包含100 nM 钙调磷酸酶,100 nM 钙调蛋白,以及5 μM 32P-标记磷酸化多肽,60 μl (总体积) 试验缓冲液包含20 mM Tris (pH 8),100 mM NaCI,6 mM MgCl2,0.5 mM 二硫苏糖醇, 每毫升0.1毫克牛血清白蛋白,以及0.1 mM CaCl2或5 mM EGTA。含细胞裂解物的反应混合物包含20 μl of未稀释裂解物, 5 μM 32P-标记的磷酸肽,和40 μl 试验缓冲液。反应混合物包含50 μM 多肽412或413和/或 500 nM冈田酸,一种磷酸酶1和2A的特异性抑制剂; 500 nM 冈田酸足以抑制Ca2+-不依赖性磷酸酶,而更高浓度时也会部分抑制Ca2+-依赖性的活性。30°C下培育15分钟,加入0.5 ml包含5% 三氯乙酸的100 mM 磷酸钾缓冲液(pH 7.0)终止反应。Dowex阳离子交换色谱分离无机磷酸盐,用闪烁计数测定数量。
细胞实验:[3]
- 合并
  • Cell lines: Jurkat细胞(无性繁殖J77)
  • Concentrations: ~100 nM
  • Incubation Time: 1小时
  • Method: 免疫抑制剂以细胞治疗浓度的1000倍溶于乙醇。细胞(106)悬浮于微量离心管1ml完全培养基中;1 μl乙醇或者Cyclosporin A乙醇溶液加入反应液中,细胞在37°C下培育1小时。细胞在冰浴下用1ml PBS洗两次,在50μl低渗缓冲液中裂解,缓冲液每毫升包含50 mM Tris (pH 7.5); 0.1 mM EGTA; 1 mM EDTA; 0.5 mM二硫苏糖醇; 以及50 微克苯甲基磺酰氯,50 微克胰蛋白酶抑制剂,5微克亮抑酶肽,和5 微克抑肽酶。裂解液用液氮冷冻,再在30°C下融化,循环3次,随后在 4°C下以12,000×g离心10分钟。
    (Only for Reference)
动物实验:[6]
- 合并
  • Animal Models: 大鼠
  • Dosages: 45毫克/千克
  • Administration: 口服
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 100 mg/mL warmed (83.15 mM)
Water Insoluble
Ethanol '''100 mg/mL warmed
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
5mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 1202.61
化学式

C62H111N11O12

CAS号 59865-13-3
储存条件 粉状
溶于溶剂
别名 Cyclosporine A, Cyclosporine, Ciclosporin, CsA

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03865888 Completed Drug: Cyclosporins|Drug: Tacrolimus Dry Eye|Sjogren Syndrome Pavly Moawd|Cairo University October 30 2018 Phase 3
NCT01762657 Withdrawn Drug: Oral Cyclosporine and Oral Lansoprazole|Drug: Placebos Type 1 Diabetes Perle Bioscience Inc. September 2014 Phase 3
NCT02130414 Completed Drug: Sandimmun® IV|Drug: CyCol® capsules Healthy Sigmoid Pharma July 2014 Phase 1
NCT01693393 Completed Drug: Cyclosporine A Sjögren´s Syndrome Charite University Berlin Germany March 2010 Phase 2

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

常见问题及建议解决方法

  • 问题 1:

    What is the difference between S2286 (cyclosporin A) and S1514 (cyclosporin)?

  • 回答:

    Cyclosporine is a mixture of Cyclosporine A, derivatives of Cyclosporine A, salts of Cyclosporine A. Cyclosporine A is an especially useful Cyclosporine component.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID